Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.

Abstract: Mobile management method and system. The method includes receiving from an application on a client a DNS query for a host name; retrieving reputation data associated with the host name from a local cache on the client; determining whether a policy associated with the host name and the reputation data associated with the host name exists; and one of: sending network flows one of: through a VPN tunnel to a server or out a local proxy on the client to a private or public network; or blocking the network flow based on the determined policy for the host name.

Abstract: The invention features methods, systems, and cartridges for amplification of target nucleic acids in complex samples, for example, whole blood. The invention also features diagnostic and therapeutic methods based on amplification of target nucleic acids characteristic of pathogens present in complex samples containing cells and/or cell debris, for example, whole blood.

Abstract: The invention features methods, systems, and panels for rapid detection of Candida species (e.g., Candida auris, Candida lusitaniae, Candida haemulonii, Candida duobushaemulonii, and Candida pseudohaemulonii) in biological samples (e.g., whole blood) and environmental samples (e.g., environmental swabs, e.g., surface swabs), and for diagnosis and monitoring of diseases, including Candidiasis and sepsis.

Abstract: A well casing security device and method. The security device includes a cover including a sidewall, a top, one or more stabilizers, and a means for attaching the cover to a well casing or to its concrete slab to render it vandal-resistant. A locking support ring is provided for attachment to either the well casing or to the concrete slab surrounding the casing. The locking support ring includes a ring body with a plurality of braces. Each of the braces includes an arm defining a slot between the arm and the ring body. The cover includes a plurality of brackets enabling rotational engagement cover with the locking support ring. Locking means are provided on the cover to lock the cover to the locking support ring. The locking means includes a key operated lock that is tamper resistant and insures that the well casing cannot be accessed easily by an intruder.

Abstract: The invention features methods, systems, and panels for rapid detection of tick-borne pathogens in a sample (including Borrelia spp. such as B. burgdorferi, B. afzelii, and B. garinii) and for diagnosis and monitoring of tick-transmitted diseases, including Lyme disease, Rocky Mountain spotted fever, Q-fever, babesiosis, ehrlichiosis, tularemia, and anaplasmosis.

Abstract: A well casing security device and method. The security device includes a cover including a sidewall, a top, one or more stabilizers, and a means for attaching the cover to a well casing or to its concrete slab to render it vandal-resistant. A locking support ring is provided for attachment to either the well casing or to the concrete slab surrounding the casing. The locking support ring includes a ring body with a plurality of braces. Each of the braces includes an arm defining a slot between the arm and the ring body. The cover includes a plurality of brackets enabling rotational engagement cover with the locking support ring. Locking means are provided on the cover to lock the cover to the locking support ring. The locking means includes a key operated lock that is tamper resistant and insures that the well casing cannot be accessed easily by an intruder.

Abstract: Methods and devices for determining device usability, e.g., for point of care assay devices. In one embodiment, the invention is to a method of determining device usability in a sensing device, including the steps of: providing a device comprising a first electrical pad; a second electrical pad; and a first polymer layer contacting at least a portion of the first and the second electrical pads and a second polymer layer contacting the first polymer layer and not the first and second electrical pads; applying a potential across the first and the second electrical pads; measuring an electrical property associated with the first and the second polymer layers; and determining whether the measured electrical property associated with the first and the second polymer layers has exceeded a threshold level associated with the device usability.

Abstract: An integrated lock and latch device for use in sliding sash windows includes a lock assembly including a sweep cam that has a pinion portion adjacent and extending downwardly from it. The pinion portion presents gear teeth extending outwardly. A tilt latch assembly including a sliding bolt is biased toward an extended position where a terminal portion of the sliding bolt extends outwardly. The sliding bolt has at least one track portion. The sweep cam is rotatably shiftable between a locked position where the sweep cam is engaged to the keeper, an intermediate unlocked position where the sweep cam is disengaged from the keeper and a tilt position where the sweep cam is disengaged from the keeper and the first gear teeth are engaged to the second gear teeth and the sliding bolt is withdrawn inwardly from the extended position.

Abstract: Methods and devices for determining sensing device usability, e.g., for point of care immunoassay devices. In one embodiment, the invention is to a method of determining device usability, comprising the steps of providing a device comprising a first electrical pad; a second electrical pad; and a continuous polymer layer contacting at least a portion of the first and second electrical pads; applying a potential across the first and second electrical pads; measuring an electrical property associated with the continuous polymer layer; and determining whether the measured electrical property associated with the continuous polymer layer has exceeded a threshold level associated with the device usability.

Abstract: An improved method for processing coiled metal sheet is provided, wherein a line threading device is inserted between the metal sheet and the process line surface at the leading edge of the metal sheet. The device is rigid and adapted to glide easily along the process line surface when propelled in a forward direction. The device has an upper surface that includes a plurality of grooves that run perpendicular to the forward direction, and the leading edge of the sheet, when it curves toward the process line surface, does not come into contact with a recess of the process line surface, but instead becomes lodged in a groove of the device, which guides the sheet along the process line surface, and does not impede forward progress.

Abstract: An improved method for processing coiled metal sheet is provided, wherein a line threading device is inserted between the metal sheet and the process line surface at the leading edge of the metal sheet. The device is rigid and adapted to glide easily along the process line surface when propelled in a forward direction. The device has an upper surface that includes a plurality of grooves that run perpendicular to the forward direction, and the leading edge of the sheet, when it curves toward the process line surface, does not come into contact with a recess of the process line surface, but instead becomes lodged in a groove of the device, which guides the sheet along the process line surface, and does not impede forward progress.

Abstract: A storage system for single serve beverage devices is provided. The storage system includes a slidable rack, capable of being positioned or mounted within a variety of known or preexisting features and having a plurality of apertures for selectively storing the devices. Beverage devices include, for example, pods or K-Cups® for providing single-serve coffee, espresso, hot chocolate, or tea drinks.

Abstract: Methods and devices for correcting sensing device signals, e.g., for point of care immunoassay devices. In one embodiment, the invention is to a method of correcting a signal in a sensing device, comprising the steps of: providing a sensing device comprising a sensor, a first electrical pad, a second electrical pad, and a continuous polymer layer contacting at least a portion of the first and second electrical pads; applying a potential across the first and second electrical pads; measuring an electrical property associated with the continuous polymer layer; determining a correction factor associated with the measured electrical property; and applying the correction factor to a signal generated by the sensor to produce a corrected signal.

Abstract: Methods and devices for determining device usability, e.g., for point of care assay devices. In one embodiment, the invention is to a method of determining device usability in a sensing device, including the steps of: providing a device comprising a first electrical pad; a second electrical pad; and a first polymer layer contacting at least a portion of the first and the second electrical pads and a second polymer layer contacting the first polymer layer and not the first and second electrical pads; applying a potential across the first and the second electrical pads; measuring an electrical property associated with the first and the second polymer layers; and determining whether the measured electrical property associated with the first and the second polymer layers has exceeded a threshold level associated with the device usability.

Abstract: Methods and devices for determining sensing device usability, e.g., for point of care immunoassay devices. In one embodiment, the invention is to a method of determining device usability, comprising the steps of providing a device comprising a first electrical pad; a second electrical pad; and a continuous polymer layer contacting at least a portion of the first and second electrical pads; applying a potential across the first and second electrical pads; measuring an electrical property associated with the continuous polymer layer; and determining whether the measured electrical property associated with the continuous polymer layer has exceeded a threshold level associated with the device usability.

Abstract: A deformable computer mouse for easy storage and portability. The mouse housing includes a flat top layer having at least two splitable pieces and an intermediate layer sliding mounted underneath. By pulling the two splitable pieces upward, the intermediate layer slides out and forms an arced surface together with the two splitable pieces, thus forming a full sized computer mouse.

Abstract: A deformable computer mouse for easy storage and portability. The mouse housing includes a flat top layer having at least two splittable pieces and an intermediate layer sliding mounted underneath. By pulling the two splittable pieces upward, the intermediate layer slides out and forms an arced surface together with the two splittable pieces, thus forming a full sized computer mouse.

Abstract: A delivery device and method for the delivery of a substance to the eye or other bodily site of a user. The device delivers the substance to the eye in the form of a non-aerosol spray or mist. The delivery device is particularly suitable for the delivery of artificial tear compositions to the ocular surface.