Patents by Inventor Lei Duan

Lei Duan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11946002
    Abstract: Provided is a method for treating an oil gas, which can realize high-efficiency separation for and recovery of gasoline components, C2, C3, and C4 components. The method first conducts separation of light hydrocarbon components from gasoline components, and then performs subsequent treatment on a stream rich in the light hydrocarbon components, during which it is no longer necessary to use gasoline to circularly absorb liquefied gas components, which significantly reduces the amount of gasoline to be circulated and reduces energy consumption throughout the separation process. Besides, in this method, impurities, such as H2S and mercaptans, in the stream rich in the light hydrocarbon components are removed first before the separation for the components. This ensures that impurities will not be carried to a downstream light hydrocarbon recovery section, thus avoiding corrosion issues caused by hydrogen sulfide in the light hydrocarbon recovery section.
    Type: Grant
    Filed: June 5, 2020
    Date of Patent: April 2, 2024
    Assignees: SINOPEC ENGINEERING INCORPORATION, SINOPEC ENGINEERING (GROUP) CO., LTD.
    Inventors: Mengqi Huang, Longhong Yu, Lei Wu, Shengyang Jiang, Yuwen Ding, Na Gao, Di Wu, Dan Duan
  • Patent number: 11921782
    Abstract: The present disclosure provides a technical solution of multi-modal chatting, which may provide response to user query by using multi-modal response in the interaction between chatbot and human beings, so that the expressing ways and the expressed content by the chatbot could be richer by using such response in a multi-modal way.
    Type: Grant
    Filed: November 1, 2019
    Date of Patent: March 5, 2024
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Nan Duan, Lei Ji, Ming Zhou
  • Patent number: 11795475
    Abstract: Provided are a cell strain HEK293.CS for reducing the production of a replication competent adenovirus, and a construction method and the use thereof. HEK293.CS is a safe adenovirus-producing cell line constructed by knocking out a gene fragment homologous to the Ad5 adenovirus E1 gene in HEK293 and providing a template plasmid to replace said gene fragment with a non-homologous sequence that stabilizes the expression of the E1 gene. Compared with the unmodified HEK293 cell strain, HEK293.CS shows no decrease in growth ability and virus production ability, but does not produce a detectable RCA. HEK293.CS can be used for the mass culture of a recombinant human type 5 adenovirus, and reducing the probability of RCA production in the manufacture process of drugs such as vaccines and antibodies.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: October 24, 2023
    Assignee: CANSINO BIOLOGICS INC.
    Inventors: Tao Zhu, Haiyan Cui, Weiwei Chen, Lei Duan, Junqiang Li, Jin Ma, Chunlin Xin, Zhongqi Shao, Xuefeng Yu, Huihua Mao
  • Publication number: 20200255862
    Abstract: Provided are a cell strain HEK293.CS for reducing the production of a replication competent adenovirus, and a construction method and the use thereof. HEK293.CS is a safe adenovirus-producing cell line constructed by knocking out a gene fragment homologous to the Ad5 adenovirus E1 gene in HEK293 and providing a template plasmid to replace said gene fragment with a non-homologous sequence that stabilizes the expression of the E1 gene. Compared with the unmodified HEK293 cell strain, HEK293.CS shows no decrease in growth ability and virus production ability, but does not produce a detectable RCA. HEK293.CS can be used for the mass culture of a recombinant human type 5 adenovirus, and reducing the probability of RCA production in the manufacture process of drugs such as vaccines and antibodies.
    Type: Application
    Filed: March 2, 2020
    Publication date: August 13, 2020
    Inventors: Tao ZHU, Haiyan CUI, Weiwei CHEN, Lei DUAN, Junqiang LI, Jin MA, Chunlin XIN, Zhongqi SHAO, Xuefeng YU, Huihua MAO
  • Patent number: 10376572
    Abstract: The invention provides an immunogenic composition for preventing pneumococcal diseases, comprising PspA-MRX1, PspA-EF5668, PspA-EF3296 and PlyL460D, wherein the amount of each component is 10-100 ?g/ml; the immunogenic composition is prepared by adding to aluminum adjuvant the corresponding dosages of the four stock solutions PspA-mRX1, PspA-EF5668, PspA-EF3296 and PlyL460D, and mixing them homogeneously; the immunogenic composition can prevent infection and invasion by Streptococcus pneumonia, covering more than 95% of the strains in clinic. The immunogenic composition has a wide application in the prevention of pneumonia, and is suitable for large-scale production in industry for its simple preparation method, low production cost, and short production cycle.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: August 13, 2019
    Assignee: CANSINO BIOLOGICS INC.
    Inventors: Tao Zhu, Lei Duan, Mingming Yang, Zhongqi Shao, Xuefeng Yu, Helen Huihua Mao, Dongxu Qiu
  • Publication number: 20180296660
    Abstract: The invention provides an immunogenic composition for preventing pneumococcal diseases, comprising PspA-MRXI, PspA-EF5668, PspA-EF3296 and PlyL460D, wherein the amount of each component is 10-100 ?g/ml; the immunogenic composition is prepared by adding to aluminum adjuvant the corresponding dosages of the four stock solutions PspA-mRXI, PspA-EF5668, PspA-EF3296 and PlyL460D, and mixing them homogeneously; the immunogenic composition can prevent infection and invasion by Streptococcus pneumonia, covering more than 95% of the strains in clinic. The immunogenic composition has a wide application in the prevention of pneumonia, and is suitable for large-scale production in industry for its simple preparation method, low production cost, and short production cycle.
    Type: Application
    Filed: April 28, 2017
    Publication date: October 18, 2018
    Inventors: Tao ZHU, Lei DUAN, Mingming YANG, Zhongqi SHAO, Xuefeng YU, Helen Huihua MAO, Dongxu QIU
  • Patent number: 9959579
    Abstract: Architecture that automatically generate concise descriptions of users in social media. The descriptions communicate classification or category of a given social media user in a small amount of viewing space. The description can be based on available metadata (e.g., user profile biography) and/or other information about that person, as may be obtained from the information data sources (e.g., structured knowledge bases) on networks such as the Internet and enterprises, for example. The descriptions can also be query-dependent, by assuming there is some relationship between the social media user and a query, in which case, the descriptions illustrate that relationship.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: May 1, 2018
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Hemant Purohit, Paul Alexander Dow, Lei Duan, Omar Alonso
  • Patent number: 9750728
    Abstract: A method of treating a patient in need of treatment for a disease selected from the group consisting of cancer, hamartoma syndrome and hereditary myopathy, the method comprising administering to the patient an effective dose of at least one PRCP and PREP dual antagonist pyridine compound of Formula (I) or an acid salt thereof, which can be administered either alone or in combination with at least one mTOR inhibitor.
    Type: Grant
    Filed: November 22, 2016
    Date of Patent: September 5, 2017
    Assignee: Targeted Therapeutics, LLC
    Inventors: Lei Duan, Victor Levenson, GuoGuang Ying
  • Patent number: 9646032
    Abstract: One or more techniques and/or systems are provided for indexing content based upon index features (e.g., temporal features, user engagement features, and/or outlier features), and/or for providing content within a search result interface based upon such index features and/or rankings. For example, user reaction data associated with content (e.g., a microblog message, a social network post, etc.) may be evaluated to generate a user engagement feature that may be constrained to a time window feature (e.g., the number of shares of a message within the first 10 minutes from publication of the message) to create an index feature for indexing the content within a content index. Responsive to the index feature corresponding to a search query, the content may be provided with search results for the search query. For example, the content may correspond to trending or breaking news associated with the search query.
    Type: Grant
    Filed: October 24, 2013
    Date of Patent: May 9, 2017
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Wenbo Wang, Lei Duan
  • Publication number: 20170119747
    Abstract: A method of treating a patient in need of treatment for a disease selected from the group consisting of cancer, hamartoma syndrome and hereditary myopathy, the method comprising administering to the patient an effective dose of at least one PRCP and PREP dual antagonist pyridine compound of Formula (I) or an acid salt thereof, which can be administered either alone or in combination with at least one mTOR inhibitor.
    Type: Application
    Filed: November 22, 2016
    Publication date: May 4, 2017
    Inventors: Lei Duan, Victor Levenson, GuoGuang Ying
  • Patent number: 9545396
    Abstract: The present invention relates to a pharmaceutical composition of PRCP antagonist, PREP antagonist, or PRCP-PREP dual antagonist. The present invention also relates to a pharmaceutical composition jointly using PRCP antagonist and mTOR antagonist, or jointly using PREP antagonist and mTOR antagonist, or jointly using PRCP-PREP dual antagonist and mTOR antagonist. In addition, the present invention also relates to a method for utilizing the pharmaceutical compositions to treat and prevent cancers and diseases related to insulin receptor substrate protein and PI3K/AKT/mTOR signal pathway.
    Type: Grant
    Filed: September 29, 2013
    Date of Patent: January 17, 2017
    Assignee: Targeted Therapeutics, LLC
    Inventors: Lei Duan, Victor Levenson, Guoguang Ying
  • Patent number: 9514216
    Abstract: Exemplary methods and apparatuses are provided which may be used for classifying and indexing segmented portions of web pages and providing related information for use in information extraction and/or information retrieval systems. In an embodiment, an index of segmented portions may be used by a search engine to respond to a search query. In an embodiment, one or more machine learned models may be used to identify one or more feature properties of a plurality of segmented portions within one or more files, or otherwise inferable from the one or more files. In an embodiment, one or more machine learned models may be used to classify one or more of a plurality of segmented portions as being at least one of a plurality of segment types.
    Type: Grant
    Filed: September 8, 2014
    Date of Patent: December 6, 2016
    Assignee: Yahoo! Inc.
    Inventors: Lei Duan, Fan Li, Srinivas Vadrevu, Emre Velipasaoglu, Swapnil Hajela, Deepayan Chakrabarti
  • Patent number: 9196534
    Abstract: A method for preparing semiconductor devices in a flip chip process comprises forming deep grooves surrounding each of the semiconductor chips; depositing a first plastic package material to form a first plastic package layer covering front surface of the semiconductor wafer and filling the deep grooves; depositing a metal layer at back surface of the semiconductor wafer after grinding; grinding an outermost portion of the metal layer thus forming a ring area located at back surface around edge of the semiconductor wafer not covered by the metal layer; cutting the first plastic package layer, the semiconductor wafer, the metal layer and the first plastic package material filled in the deep grooves along a straight line formed by two ends of each of the deep grooves filled with the first plastic package material; and picking up the semiconductor devices and mounting on a substrate without flipping the semiconductor devices.
    Type: Grant
    Filed: February 24, 2013
    Date of Patent: November 24, 2015
    Assignee: Alpha and Omega Semiconductor Incorporated
    Inventors: Yan Xun Xue, Ping Huang, Hamza Yilmaz, Yueh-Se Ho, Lei Shi, Liang Zhao, Ping Li Wu, Lei Duan, Yuping Gong
  • Publication number: 20150328197
    Abstract: The present invention relates to a pharmaceutical composition of PRCP antagonist, PREP antagonist, or PRCP-PREP dual antagonist. The present invention also relates to a pharmaceutical composition jointly using PRCP antagonist and mTOR antagonist, or jointly using PREP antagonist and mTOR antagonist, or jointly using PRCP-PREP dual antagonist and mTOR antagonist. In addition, the present invention also relates to a method for utilizing the pharmaceutical compositions to treat and prevent cancers and diseases related to insulin receptor substrate protein and PI3K/AKT/mTOR signal pathway.
    Type: Application
    Filed: September 29, 2013
    Publication date: November 19, 2015
    Applicant: TARGETED THERAPEUTICS, LLC
    Inventors: Lei Duan, Victor Levenson, Guoguang Ying
  • Patent number: 9104751
    Abstract: Systems, methods, and computer-readable storage media for presenting supplemental search results having indications that identified documents have been endorsed by the user and/or social network connections of the user are provided. A search query is received and it is determined that the user's social networking data is available. Documents that have been endorsed by the user and/or social network connections of the user are searched to identify those that satisfy the input search query. The satisfying documents are assigned a relevance score to determine whether each satisfying document is relevant enough to be shown and to determine placement of the document on the SERP relative to standard search results. Upon rendering of the SERP, a supplemental search result identifying documents that were endorsed by the user and/or social network connections of the user is presented, as is an indication about which social network connection(s) of the user endorsed the document.
    Type: Grant
    Filed: December 30, 2011
    Date of Patent: August 11, 2015
    Assignee: MICROSOFT TECHNOLOGY LICENSING, LLC
    Inventors: Yajie Siamwalla, Rajesh Krishna Shenoy, Lei Duan, Satish Kumar Musukula, Charles C. Carson, Jr., Michael Ching
  • Publication number: 20150120753
    Abstract: One or more techniques and/or systems are provided for indexing content based upon index features (e.g., temporal features, user engagement features, and/or outlier features), and/or for providing content within a search result interface based upon such index features and/or rankings. For example, user reaction data associated with content (e.g., a microblog message, a social network post, etc.) may be evaluated to generate a user engagement feature that may be constrained to a time window feature (e.g., the number of shares of a message within the first 10 minutes from publication of the message) to create an index feature for indexing the content within a content index. Responsive to the index feature corresponding to a search query, the content may be provided with search results for the search query. For example, the content may correspond to trending or breaking news associated with the search query.
    Type: Application
    Filed: October 24, 2013
    Publication date: April 30, 2015
    Applicant: Microsoft Corporation
    Inventors: Wenbo Wang, Lei Duan
  • Patent number: 9015174
    Abstract: A plurality of web documents that include indicators corresponding to one or more selectable like objects may be obtained. A corresponding web domain associated with each of the plurality of obtained web documents may be determined. A domain total like object count of the indicators corresponding to the one or more selectable like objects may be determined for each one of the obtained plurality of web documents, for each determined corresponding web domain. A candidate group of the corresponding web domains may be determined based on a comparison of a predetermined first threshold value with one or more of the domain total like object counts. A likefarm domain confidence score may be determined for each one of a second group of the corresponding web domains based on a decision tree function that is based on a plurality of domain attributes.
    Type: Grant
    Filed: December 16, 2011
    Date of Patent: April 21, 2015
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Lei Duan, Will Chin, Seokkyung Chung, Lei Guo, Guenther Schmuelling
  • Publication number: 20150066934
    Abstract: Exemplary methods and apparatuses are provided which may be used for classifying and indexing segmented portions of web pages and providing related information for use in information extraction and/or information retrieval systems.
    Type: Application
    Filed: September 8, 2014
    Publication date: March 5, 2015
    Inventors: Lei Duan, Fan Li, Srinivas Vadrevu, Emre Velipasaoglu, Swapnil Hajela, Deepayan Chakrabarti
  • Patent number: 8849725
    Abstract: Exemplary methods and apparatuses are provided which may be used for classifying and indexing segmented portions of web pages and providing related information for use in information extraction and/or information retrieval systems.
    Type: Grant
    Filed: August 10, 2009
    Date of Patent: September 30, 2014
    Assignee: Yahoo! Inc.
    Inventors: Lei Duan, Fan Li, Srinivas Vadrevu, Emre Velipasaoglu, Swapnil Hajela, Deepayan Chakrabarti
  • Patent number: D1019030
    Type: Grant
    Filed: October 16, 2021
    Date of Patent: March 19, 2024
    Assignee: Beijing Shunzao Technology Co., Ltd.
    Inventors: Lei Zhao, Chongyue Xu, Cheng Tang, Fei Duan, Liang Zhong