Patents by Inventor Lei Shen
Lei Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250145464Abstract: A method for preparing mesoporous iron phosphate by induction of block copolymers is provided. The method comprises preparing a ferric salt solution having a certain concentration and evenly dispersing it into a dispersant, then evenly mixing a structure directing agent solution with a phosphorus source solution, next adding the mixed solution to the ferric salt solution while dropwise adding an oxidant and stirring to react, thus after ending the reaction, washing, drying and calcinating the reaction product to obtain mesoporous iron phosphate.Type: ApplicationFiled: April 21, 2023Publication date: May 8, 2025Applicant: YIDU XINGFA CHEMICAL CO., LTDInventors: Jie WANG, Baorui LUO, Weiyun SHEN, Chi ZHANG, Lei ZHENG, Haiquan TAN, Zujing WANG, Dong WANG
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Publication number: 20250150373Abstract: A network bandwidth estimation method and apparatus, an electronic device and a storage medium are provided. The method includes: sending a bandwidth test file to a service terminal, and respectively acquiring network state parameters before and after sending the bandwidth test file, wherein a volume of the bandwidth test file is less than a preset file volume threshold; determining a first network bandwidth and a second network bandwidth based on the network state parameters and the volume of the bandwidth test file; inputting the network state parameters, the first network bandwidth, and the second network bandwidth into a current latest network bandwidth estimation model to obtain a target network bandwidth estimation result.Type: ApplicationFiled: February 6, 2023Publication date: May 8, 2025Inventors: Liyang SUN, Mingming SHEN, Lei ZHAI, Hao DONG, Qian MA
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Publication number: 20250121005Abstract: The compositions and methods described herein are directed to treating solid tumors using CAR T therapy. For example, the compositions include CAR T cells comprising an extracellular domain that binds OR2I1P, LY6G6D, LRRC15, LY6K, GCC, GFRA4, F2RL2, QRFPR, IQGAP3, SIGLEC15, HAVCR1, PSG9, KISS1R, PRAME, HCN4, DPEP3, TMEM270, HER2, SLC7A3, SPRR2F, SLC45A2, CHRM1, CHRNA2, STEAP1B, FCRL2, Luteinizing hormone receptor, EDB, or CLDN18.2.Type: ApplicationFiled: January 31, 2023Publication date: April 17, 2025Applicants: Innovative Cellular Therapeutics Holdings, Ltd., Innovative Cellular Therapeutics, Inc.Inventors: Wei Ding, Xiaogang Shen, Xianyang Jiang, Guiting Han, Wensheng Wang, Xudong Tang, Chengfei Pu, Zhiyuan Cao, Zhao Wu, Lei Xiao, Le Tian
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Publication number: 20250120492Abstract: A multifunctional nail polishing head includes a grinding head and a grinding handle, a plurality of first helical grooves are defined on a circumferential wall of the grinding head at intervals, the grinding head is provided with a rack between every two adjacent ones of the plurality of first helical grooves, in a radial section of the grinding head, a plurality of sets of large tooth segment are formed along a circumferential direction of the grinding head, each set of the plurality of sets of large tooth segment consists of a plurality of racks, an arrangement density of the plurality of racks in one set of the plurality of sets of large tooth segment is from sparse to dense, or from dense to sparse, or alternates dense and sparse along the circumferential direction of the grinding head.Type: ApplicationFiled: January 22, 2024Publication date: April 17, 2025Inventors: Mengyi WANG, Jishun WANG, Jing SUN, Wenlong JIANG, Bo SUN, Lei LIU, Ren LIU, Jiahe SHEN, Caiyun YANG
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Publication number: 20250126730Abstract: A hinge mechanism and a foldable electronic device are provided. The hinge mechanism is disposed in a foldable electronic device. When one rotation portion of the foldable electronic device moves, the hinge mechanism drives the other rotation portion to move. The hinge mechanism includes a fastening support, a transmission assembly, two first transmission shafts, a clamping assembly, and a first elastic portion. The fastening support is configured to be fastened to a base of the foldable electronic device, and the fastening support is coupled to the first transmission shaft to limit relative positions of the first transmission shaft and the fastening support. The first transmission shaft is coupled to the clamping assembly and the first elastic portion. The first elastic portion provides an elastic force for the clamping assembly such that friction between the clamping assembly and the transmission assembly generates damping.Type: ApplicationFiled: December 23, 2024Publication date: April 17, 2025Inventors: Hewen Shen, Xuechan Wang, Li Liao, Lei Yu, Wenwen Wu
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Publication number: 20250125723Abstract: A direct current (DC)-DC conversion circuit for balancing direct current buses is provided, including: a first switching transistor, a second switching transistor, a third switching transistor, and a fourth switching transistor that are connected in series between direct current buses, and are respectively connected in antiparallel with a diode; a first inductor, one end of which is connected to a positive electrode of a battery, and a second end is connected to a first node; a second inductor, one end of which is connected to a negative electrode of the battery, and a second end of which is connected to a third node; a first switch, connected between the first inductor and the positive electrode of the battery or between the second inductor and the negative electrode of the battery; and a third switch and a third inductor that are connected in parallel, connected between a second node and a ground.Type: ApplicationFiled: October 2, 2024Publication date: April 17, 2025Inventors: Zhimin Shen, Lei Cao, Binchuang Zhu, Yulong Hao, Jin Ouyang
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Patent number: 12278595Abstract: A cleaning robot includes a supporting mechanism, cleaning mechanisms and a walking mechanism. The supporting mechanism is used for supporting the cleaning robot; the cleaning mechanisms are symmetrically arranged at the two ends of the supporting mechanism and can clean the surface of a photovoltaic panel; the walking mechanism is arranged in the middle of the supporting mechanism and can fix the cleaning robot to the surface of the photovoltaic panel and drive the cleaning robot to move on the surface of the photovoltaic panel; and the supporting mechanism can adjust the cleaning ranges of the cleaning mechanisms, so that the cleaning mechanisms at least have a first cleaning range and a second cleaning range, and the first cleaning range and the second cleaning range can be concentric circles. The cleaning robot is small and exquisite in structure and light. One person can operate multiple robots at the same time.Type: GrantFiled: June 17, 2021Date of Patent: April 15, 2025Assignee: SUZHOU IFBOT INTELLIGENT TECHNOLOGY CO., LTD.Inventors: Xiangbo Shen, Xiangming Dun, Wujun Chen, Zhongliang Jing, Xiangyong Dun, Lei Shan, Xincheng Lu, Jiageng Chen, Ying Gao, Sihai Zhou, Hongbo Zhou, Zhixiong Hu
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Fully bio-based, highly filled lignin-rubber masterbatch, method for preparing same, and use thereof
Patent number: 12269952Abstract: The present invention discloses a fully bio-based, highly filled lignin-rubber masterbatch, a method for preparing same, and use thereof. The lignin-rubber masterbatch is prepared by a method comprising: (1) reacting a lignin, acetic acid, and oleic acid in the presence of a catalyst to give a modified lignin; and (2) blending the modified lignin and a rubber, and granulating to give the lignin-rubber masterbatch. The highly filled lignin-rubber masterbatch prepared by the present invention can replace the conventional reinforcing agent carbon black and provide a better reinforcing effect and higher mechanical properties for rubber materials. The present invention can also reduce the rubber content of the rubber composite materials while retaining the mechanical properties, thus featuring cost-efficiency.Type: GrantFiled: August 17, 2024Date of Patent: April 8, 2025Assignee: NANJING TECH UNIVERSITYInventors: Chenjie Zhu, Haifeng Liu, Ming Li, Lei Ji, Zhiwei Chang, Yixin Feng, Zhuotao Tan, Tao Shen, Hanjie Ying -
Publication number: 20250108122Abstract: A pharmaceutical composition comprising an anti-CD79b antibody-drug conjugate and use thereof. The pharmaceutical composition comprises a ligand-drug conjugate and a buffer. In the ligand-drug conjugate, the ligand is an anti-CD79b antibody or an antigen-binding fragment thereof, and the drug is selected from MMAE or a derivative thereof, exatecan or a derivative thereof, and eribulin or a derivative thereof. The buffer is selected from an acetate buffer, a histidine salt buffer, a Tris-hydrochloride buffer, a Tris-citrate buffer, a phosphate buffer, and a succinate buffer. The composition is used for preparing a medicament for treating or preventing a proliferative disease.Type: ApplicationFiled: January 19, 2023Publication date: April 3, 2025Inventors: Lijun SHEN, Zhilong ZHAO, Chenxiang TANG, Lei LI
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Patent number: 12267303Abstract: A structural encoding unit and an error correction decoding unit are divided. The structure encoding unit is divided into input branch processor and an input proxy processor; and the error correction decoding unit is divided into an output routing processor, an output proxy processor, an adjudication branch processor, an adjudication proxy processor and a voting processor. The input branch processor is used for duplicating and distributing messages, the arbitration branch processor is used for duplicating and distributing data, the voting processor is used for performing voting, and the output routing processor is used for selecting an output result from processing results of the output proxy processor according to a voting result of the voting processor.Type: GrantFiled: June 7, 2021Date of Patent: April 1, 2025Assignees: CHINA NATIONAL DIGITAL SWITCHING SYSTEM ENGINEERING & TECHNOLOGICAL R&D CENTER, PURPLE MOUNTAIN LABORATORIESInventors: Lei He, Jiangxing Wu, Qinrang Liu, Ke Song, Shuai Wei, Jianliang Shen, Libo Tan, Yu Li, Quan Ren, Jun Zhou, Min Fu, Weili Zhang, Ruihao Ding, Yiwei Guo
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Patent number: 12264104Abstract: The invention relates to a multi-component composition for the manufacture of polyurethane/urea cementitious hybrid system, comprising at least one isocyanate component selected from the group consisting of monoisocyanate, polyisocyanate and NCO terminated prepolymer, at least one polyol, water, catalyst, at least one acidic additive, and hydraulic binder, wherein the acidic additive is at least one selected from the group consisting of Lewis acids, acid precursors and acidic buffers and is in an amount of 0.01 to 3 wt %, based on the total weight of the composition, to the preparation thereof, and to the use of the composition for the preparation of a flooring, waterproofing, screed, grouting, primer, wall paint, roofing or coating in construction applications.Type: GrantFiled: January 31, 2020Date of Patent: April 1, 2025Assignee: SIKA TECHNOLOGY AGInventors: Hang Xu, Jie Shen, ShengZhong Zhou, Stefan Hirsemann, Andrew Tasker, Josef Weichmann, Lei Guo
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Patent number: 12255721Abstract: A method which may be performed by a base station, may include obtaining a predicted transmission configuration indicator (TCI) subset for a user equipment (UE); and determining the TCI subset corresponding to the UE based on the predicted TCI subset. The step of obtaining the predicted TCI subset in the solution may be implemented by using a trained artificial intelligence model. Since the beams in the predicted TCI subset may fit the movement trend of the UE, then the target serving beam for the UE when performing serving beam switching may belong to the predicted TCI subset with a greater possibility, thus reducing the occurrence of high delay scenarios when the UE performs the serving beam switching, and thus reducing the beam switching delay.Type: GrantFiled: May 8, 2023Date of Patent: March 18, 2025Assignee: Samsung Electronics Co., Ltd.Inventors: Liying Zhou, Lei Wang, Yiyan Zhang, He Wang, Songhui Shen, Chaeman Lim
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Patent number: 12247036Abstract: The present invention relates to compounds of formula (Ib), wherein R1 to R3, M and L are as described herein, and their pharmaceutically acceptable salt, enantiomers and diastereomers thereof, and compositions including the compounds and methods of using the compounds.Type: GrantFiled: August 22, 2024Date of Patent: March 11, 2025Assignee: Hoffmann-La Roche Inc.Inventors: Jianguo Chen, Lei Guo, Haixia Liu, Hong Shen, Junwei Xi, Weixing Zhang, Dan Zhao, Wei Zhu
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Patent number: 12249008Abstract: A method for diagnostic imaging reconstruction uses a prior image xpr from a scan of a subject to initialize parameters of a neural network which maps coordinates in image space to corresponding intensity values in the prior image. The parameters are initialized by minimizing an objective function representing a difference between intensity values of the prior image and predicted intensity values output from the neural network. The neural network is then trained using subsampled (sparse) measurements of the subject to learn a neural representation of a reconstructed image. The training includes minimizing an objective function representing a difference between the subsampled measurements and a forward model applied to predicted image intensity values output from the neural network. Image intensity values output from the trained neural network from coordinates in image space input to the trained neural network are computed to produce predicted image intensity values.Type: GrantFiled: September 14, 2022Date of Patent: March 11, 2025Assignee: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Liyue Shen, Lei Xing
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Publication number: 20250075933Abstract: A building chiller/heat pump system includes a chiller/heat pump system for supplying a conditioned fluid to change a temperature of air being delivered into a building. The chiller/heat pump system is provided with a control to achieve a desired setpoint of the air delivered into the building. The control is programmed to receive a prediction of expected remission levels in energy that will be delivered to power the chiller/heat pump system. The control is programmed to change the setpoint such that an energy level required to operate the chiller/heat pump system to achieve the setpoint will drop when the expected emissions level increases, and adjusts the setpoint in an opposed direction when the expected emissions drops. A method is also disclosed.Type: ApplicationFiled: August 28, 2024Publication date: March 6, 2025Inventors: Wei Huang, Lei Yu, Claus Daniel, Stella Maris Oggianu, Runfu Shi, Guy DeLuca, Mark Makwinski, Rebecca Shen, Mann-Fai Yip, Shaw Ping Lee, Chai Kheh Chew
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Patent number: 12233844Abstract: A method for controlling an interference torque for a vehicle is provided. The method is applied to a new energy vehicle including an electric motor and an engine, and includes steps of: arbitrating between a pedal torque of a driver and an interference torque required by ESP; performing an initial allocation on the electric motor and/or the engine in response to the pedal torque when the vehicle is in a hybrid drive mode, to meet an engine torque request while ensuring that the engine is operated at an optimal operation point; and determining, based on the initial allocation, whether the motor is capable of fully responding to the arbitrated torque, if so, controlling the motor to respond to the arbitrated torque in priority, otherwise controlling the engine and the motor to cooperatively respond to the arbitrated torque.Type: GrantFiled: June 11, 2021Date of Patent: February 25, 2025Assignee: GREAT WALL MOTOR COMPANY LIMITEDInventors: Jie Zhang, Xiao Wang, Hailan Wang, Lei Zhang, Haijun Song, Nan Zhang, Yan Sun, Yazhou Shen
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Patent number: 12230800Abstract: This application discloses a secondary battery including a positive electrode plate and a negative electrode plate, wherein the positive electrode plate comprises a positive electrode current collector and a positive electrode film disposed on a surface of the positive electrode current collector and comprising a positive active material, the negative electrode plate comprises a negative electrode current collector and a negative electrode film disposed on a surface of the negative electrode current collector and comprising a negative active material. The positive active material comprises one or more of layered lithium transition metal oxides and modified compounds thereof, and a resistance R of the negative electrode plate satisfies: 6.0 m??R?12.0 m?; or the positive active material comprises one or more of lithium-containing phosphates with olivine structure and modified compounds thereof, and a resistance R of the negative electrode plate satisfies: 3.0 m??R?7.0 m?.Type: GrantFiled: December 10, 2021Date of Patent: February 18, 2025Assignee: CONTEMPORARY AMPEREX TECHNOLOGY (HONG KONG) LIMITEDInventors: Jianjun Ma, Rui Shen, Libing He, Baojian Zhu, Lei Chen
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Patent number: 12227811Abstract: A primer group for simultaneous detection of 15 porcine pathogens through high-throughput targeted amplicon sequencing and use thereof are provided. The primer group for simultaneous detection of 15 porcine pathogens through high-throughput targeted amplicon sequencing includes: primers having nucleotide sequences set forth in SEQ ID NO: 1 to SEQ ID NO: 302. The nucleotide sequences of pathogenic target genes are set forth in SEQ ID NO: 303 to SEQ ID NO: 344. The primer group of the present invention is used for amplicon sequencing detection analysis method for 42 target genes of 15 porcine respiratory pathogens, has the technical advantages of rapidness, high efficiency, high targeting, strong specificity, and the like, and is suitable for rapid and accurate simultaneous diagnosis of multiple pathogens of diseased pigs in pig farms.Type: GrantFiled: November 15, 2023Date of Patent: February 18, 2025Assignee: China Agricultural UniversityInventors: Shaolin Wang, Yang Zuo, Zhangqi Shen, Lei Zhou, Jun Han, Jianzhong Shen
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Publication number: 20250055686Abstract: A processor with an elliptic curve cryptographic algorithm and a data processing method thereof are shown. Three elliptic curve cryptographic instructions are proposed in the instruction set architecture for key exchange between an initiator and a responder. The initiator device executes the first elliptic curve cryptographic instruction to generate a key pair (rA, RA). In addition to considering the first temporary public key RA, the responder device further takes the second temporary public key RB into consideration when executing the second elliptic curve cryptographic instruction to generate the responder-generated shared key KB. Based on the temporary private key rA, and the temporary public keys RA and RB, the initiator device executes the third elliptic curve cryptographic instruction to generate the initiator-generated shared key KA.Type: ApplicationFiled: October 18, 2024Publication date: February 13, 2025Inventors: Yanting LI, Zhenhua HUANG, Yingbing GUAN, Yun SHEN, Lei YI, Shuang YANG
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Patent number: 12222550Abstract: A light scattering patch device and preparation method thereof is disclosed. The light scattering patch device is composed of a patch, an air gap, and a tapered optical fiber; the patch is a transparent patch; a refractive index of the patch is greater than a refractive index of a biological tissue; a tip, a tapered transition zone and a partial unstretched zone of the tapered optical fiber are embedded in the patch, and the air gap is formed between the tip and the tapered transition zone of the tapered optical fiber and the patch. The method of preparing the light scattering patch device comprises: first preparing the tapered optical fiber, then performing hydrophobic modification on the surface of the tapered optical fiber; placing the tapered optical fiber in an uncured polymer and curing the uncured polymer, and pulling the unstretched part; connecting the unstretched part of the tapered optical fiber.Type: GrantFiled: August 2, 2022Date of Patent: February 11, 2025Assignee: ZHEJIANG UNIVERSITYInventors: Yang Zhu, Lei Zhang, Yao Tang, Kaicheng Deng, Liyin Shen