Patents by Inventor Leif Andersson

Leif Andersson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7785778
    Abstract: Identification of a pig as resistant or non-resistant to enterotoxigenic E. Coli (ETEC). Particularly, there is provided methods, probes and DNA molecules involved in identifying a pig as resistant or non-resistant to ETEC. There is also provided methods for breeding pigs using the information of resistance/non-resistance, mixed boar semen, and methods for developing drugs to compensate for non-resistance to ETEC.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: August 31, 2010
    Assignee: University of Copenhagen
    Inventors: Claus Böttcher Jörgensen, Susanna Cirera, Alan Archibald, Leif Andersson, Merete Fredholm, Inger Edfors-Lilia
  • Patent number: 7732137
    Abstract: The invention relates to methods to select animals, such as mammals, particularly domestic animals, such as breeding animals or animals destined for slaughter, for having desired genotypic or potential phenotypic properties, in particular, related to muscle mass and/or fat deposition lean meat, lean back fat, sow prolificacy and/or sow longevity. Provided is a method for selecting an animal for having desired genotypic or potential phenotypic properties comprising testing the animal, a parent of the animal or its progeny for the presence of a nucleic acid modification affecting the activity of an evolutionary conserved CpG island, located in intron 3 of an IGF2 gene and/or for the presence of a nucleic acid modification affecting binding of a nuclear factor to an IGF2 gene.
    Type: Grant
    Filed: February 17, 2006
    Date of Patent: June 8, 2010
    Assignees: University of Liege, Melica HB, Gentec N.V.
    Inventors: Leif Andersson, Goran Andersson, Michel Georges, Nadine Buys
  • Publication number: 20090197252
    Abstract: The present invention relates to a polypeptide which is flavin-containing monooxygenase 3 (FMO3), wherein said FMO3 is a polypeptide comprising at least a sequence having at least 85% identity with the polypeptide sequence SEQ ID NO: 15, in particular to a polypeptide which is a functionally altered mutant of flavin-containing mono oxygenase 3 (FMO3) leading to a buildup of trimethylamine in an animal. Further, the invention relates to nucleic acid sequences encoding said polypeptide, and to the complements of such nucleic acid sequences. Such nucleic acid sequences and fragments thereof may be useful e.g. as primers. The invention further relates to various methods for determining the presence in e.g. a nucleic acid sample of a nucleic acid sequence encoding a mutated FMO3 polypeptide.
    Type: Application
    Filed: September 10, 2007
    Publication date: August 6, 2009
    Inventors: Anne Lunden, Leif Andersson, Stefan Marklund
  • Patent number: 7462693
    Abstract: Variants of the gamma chain of vertebrate AMP-activated kinase (AMPK), as well as nucleic acid sequences encoding the variants and use thereof for the diagnosis or treatment of dysfunction of energy metabolisms.
    Type: Grant
    Filed: January 24, 2007
    Date of Patent: December 9, 2008
    Assignee: Arexis AB
    Inventors: Leif Andersson, Christian Looft, Ernst Kalm, Denis Milan, Annie Robic, Claire Rogel-Gaillard, Nathalie Iannuccelli, Joel Gellin, Pascale Le Roy, Patrick Chardon
  • Patent number: 7382444
    Abstract: The invention relates to an electronic distance measuring apparatus for surveying, e.g. for measuring the distance from the apparatus to an object. The apparatus comprises: a) an objective lens (101), defining an optical axis (OA), b) at least two sources (111, 112) of structured light for transmitting beams (?1, ?2) of separate wavelengths towards said object, said beams on reflection from said object received by the objective lens (101), (c) at least two receivers (141, 142) arranged outside a beam path (109) as defined by the objective lens (101), and adapted to receive said received beams (?1, ?2) of structured light.
    Type: Grant
    Filed: June 18, 2003
    Date of Patent: June 3, 2008
    Assignee: Trimble AB
    Inventors: Leif Andersson, Mikael Herzman, Christian Grässer, Rolf Richter
  • Patent number: 7371521
    Abstract: Methods for determining the KIT genotype of pigs are provided. These methods are useful in determining coat colour genotype, breed determination and for screening pigs to determine those likely to produce larger litters, and/or those less likely to produce large litters. Kits for use in such methods are also provided.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: May 13, 2008
    Assignee: Pig Improvement Company UK, Limited
    Inventors: Leif Andersson, Elisabetta Giuffra, Graham Stuart Plastow, Olwen Irene Southwood
  • Patent number: 7371205
    Abstract: A rotor assembly for centrifuging reaction vessels containing reaction mixtures in a device for asymmetric heating and cooling of reaction mixtures during centrifugation. The rotor contains at least one fan blade used to force ambient gas to pass the reaction mixture. Also provided is a device for asymmetric heating and cooling of reaction mixtures during centrifugation.
    Type: Grant
    Filed: November 18, 2003
    Date of Patent: May 13, 2008
    Assignee: Alphahelix Molecular Diagnostics AB
    Inventors: Leif Andersson, Mats Malmqvist
  • Publication number: 20080050767
    Abstract: Transgenic non-human animals that express the ?3 subunit of PRKAG are described, as well as methods of using the transgenic non-human animals as models for improving treatment, prevention, or diagnosis of diseases related to energy metabolism, including obesity, dyslipidemia, insulin resistance syndrome, and type 2 diabetes.
    Type: Application
    Filed: May 4, 2007
    Publication date: February 28, 2008
    Inventors: Leif Andersson, Stefan Marklund
  • Patent number: 7285385
    Abstract: The present invention provides methods for analysing animal products. In particular methods for differentiating animal products on the basis of breed origin or validating an animal product are provided.
    Type: Grant
    Filed: January 16, 2004
    Date of Patent: October 23, 2007
    Assignee: Pig Improvement Company UK Limited
    Inventors: Leif Andersson, James Kijas, Elisabetta Giuffra, Gary Jon Evans, Richard Wales, Graham Stuart Plastow
  • Patent number: 7273703
    Abstract: The present invention relates to a polypeptide which is a flavin-containing monooxygenase 3 (FMO3), wherein said FMO3 is a polypeptide comprising at least a sequence having at least 85% identity with the polypeptide sequence SEQ ID NO: 15, in particular to a polypeptide which is a functionally altered mutant of flavin-containing mono oxygenase 3 (FMO3) leading to a buildup of trimethylamine in an animal. Further, the invention relates to nucleic acid sequences encoding said polypeptide, and to the complements of such nucleic acid sequences. Such nucleic acid sequences and fragments thereof may be useful e.g. as primers. The invention further relates to various methods for determining the presence in e.g. a nucleic acid sample of a nucleic acid sequence encoding a mutated FMO3 polypeptide.
    Type: Grant
    Filed: January 9, 2003
    Date of Patent: September 25, 2007
    Assignee: FunboGen AB
    Inventors: Anne Lunden, Leif Andersson, Stefan Marklund
  • Publication number: 20070199081
    Abstract: Variants of the gamma chain of vertebrate AMP-activated kinase (AMPK), as well as nucleic acid sequences encoding the variants and use thereof for the diagnosis or treatment of dysfunction of energy metabolisms.
    Type: Application
    Filed: January 24, 2007
    Publication date: August 23, 2007
    Inventors: Leif Andersson, Christian Looft, Ernst Kalm, Denis Milan, Annie Robic, Claire Rogel-Gaillard, Nathalie Iannuccelli, Joel Gellin, Pascale Le Roy, Patrick Chardon
  • Patent number: 7255987
    Abstract: The invention relates to methods to select breeding animals or animals destined for slaughter for having desired genotypic or potential phenotypic properties, in particular related to muscle mass and/or fat deposition. The invention provides a method for selecting a pig for having desired genotypic or potential phenotypic properties comprising testing a sample from said pig for the presence of a quantitative trait locus (QTL) located at a Sus scrofa chromosome 2 mapping at position 2p1.7.
    Type: Grant
    Filed: December 16, 1999
    Date of Patent: August 14, 2007
    Assignees: Melica HB, University of Liege, Seghersgentec N.V.
    Inventors: Leif Andersson, Michel Georges, Geert Spincemaille, Carina Danielle A. Nezer
  • Patent number: 7214850
    Abstract: Transgenic non-human animals that express the ?3 subunit of PRKAG are described, as well as methods of using the transgenic non-human animals as models for improving treatment, prevention, or diagnosis of diseases related to energy metabolism, including obesity, dyslipidemia, insulin resistance syndrome, and type 2 diabetes.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: May 8, 2007
    Assignee: Arexis AB
    Inventors: Leif Andersson, Stefan Marklund
  • Publication number: 20070006333
    Abstract: The invention relates to methods to select animals, such as mammals, particularly domestic animals such as breeding animals or animals destined for slaughter for having desired genotypic or potential phenotypic properties, in particular related to muscle mass and/or fat deposition lean meat, lean back fat, sow prolificacy and/or sow longevity. Provided is a method for selecting an animal for having desired genotypic or potential phenotypic properties comprising testing said animal, a parent of said animal or its progeny for the presence of a nucleic acid modification affecting the activity of an evolutionary conserved CpG island, located in intron 3 of an IGF2 gene and/or for the presence of a nucleic acid modification affecting binding of a nuclear factor to an IGF2 gene.
    Type: Application
    Filed: February 17, 2006
    Publication date: January 4, 2007
    Applicants: University of Liege, Melica HB, Gentec B.V.
    Inventors: Leif Andersson, Goran Andersson, Michel Georges, Nadine Buys
  • Publication number: 20060288433
    Abstract: The present invention relates to a method for selecting a domestic animal having desired genotypic properties comprising testing the animal for the presence of a parentally imprinted quantitative trait locus (QTL). The invention further relates to the use of an isolated and/or recombinant nucleic acid comprising a QTL or functional fragment derived therefrom to select a breeding animal or animal destined for slaughter having desired genotypic or potential phenotypic properties. In particular, the properties are related to muscle mass, fat deposition, sow prolificacy, and/or sow longevity.
    Type: Application
    Filed: August 17, 2006
    Publication date: December 21, 2006
    Applicants: University of Liege, Melica HB, SEGHERSgentec N.V.
    Inventors: Leif Andersson, Michel Georges, Geert Spincemaille, Carine Nezer
  • Publication number: 20060275763
    Abstract: Identification of a pig as resistant or non-resistant to enterotoxigenic E. Coli (EIEC). Particularly, there is provided methods, probes and DNA molecules involved in identifying a pig as resistant or non-resistant to ETEC. There is also provided methods for breeding pigs using the information of resistance/non-resistance, mixed boar semen, and methods for developing drugs to compensate for non-resistance to ETEC.
    Type: Application
    Filed: November 25, 2003
    Publication date: December 7, 2006
    Inventors: Claus Jorgensen, Susanna Cirera, Alan Archibald, Leif Andersson, Merete Fredholm, Inger Edfors-Lilia
  • Publication number: 20060147910
    Abstract: The present invention relates to a polypeptide which is a flavin-containing monooxygenase 3 (FMO3), wherein said FMO3 is a polypeptide comprising at least a sequence having at least 85% identity with the polypeptide sequence SEQ ID NO: 15, in particular to a polypeptide which is a functionally altered mutant of flavin-containing mono oxygenase 3 (FMO3) leading to a buildup of trimethylamine in an animal. Further, the invention relates to nucleic acid sequences encoding said polypeptide, and to the complements of such nucleic acid sequences. Such nucleic acid sequences and fragments thereof may be useful e.g. as primers. The invention further relates to various methods for determining the presence in e.g. a nucleic acid sample of a nucleic acid sequence encoding a mutated FMO3 polypeptide.
    Type: Application
    Filed: January 9, 2003
    Publication date: July 6, 2006
    Applicant: Arexis AB, a corporation of Sweden
    Inventors: Anne Lunden, Leif Andersson, Stefan Marklund
  • Publication number: 20060142134
    Abstract: The invention relates to rotor means (5) for centrifuging reaction vessels containing reaction mixtures in a device for asymmetric heating and cooling of reaction mixtures during centrifugation. The rotor means (5) comprise/-s at least one fan blade (18), which force ambient gas to pass the reaction mixtures. The invention also relates to a device for asymmetric heating and cooling of reaction mixtures during centrifugation comprising said rotor means (5).
    Type: Application
    Filed: November 18, 2003
    Publication date: June 29, 2006
    Inventors: Leif Andersson, Mats Malmqvist
  • Publication number: 20060114448
    Abstract: The invention relates to an electronic distance measuring apparatus for surveying, e.g. for measuring the distance from the apparatus to an object. The apparatus comprises: a) an objective lens (101), defining an optical axis (OA), b) at least two sources (111, 112) of structured light for transmitting beams (?1, ?2) of separate wavelengths towards said object, said beams on reflection from said object received by the objective lens (101), (c) at least two receivers (141, 142) arranged outside a beam path (109) as defined by the objective lens (101), and adapted to receive said received beams (?1, ?2) of structured light.
    Type: Application
    Filed: June 18, 2003
    Publication date: June 1, 2006
    Inventors: Leif Andersson, Mikael Herzman, Christian Grasser, Rolf Richter
  • Publication number: 20060037090
    Abstract: The invention relates to methods to select animals, such as mammals, in particular, domestic animals such as breeding animals or animals destined for slaughter, for having desired genotypic or potential phenotypic properties, in particular, related to muscle mass and/or fat deposition or, in the case of mammals, to teat number. The invention provides a method for selecting an animal for having desired genotypic or potential phenotypic properties comprising testing the animal, a parent of the animal or its progeny for the presence of a nucleic acid modification affecting the activity of an evolutionary conserved CpG island, located in intron 3 of an IGF2 gene and/or for the presence of a nucleic acid modification affecting binding of a nuclear factor to an IGF2 gene.
    Type: Application
    Filed: July 8, 2005
    Publication date: February 16, 2006
    Applicants: University of Liege, Melica HB, Gentec B.V.
    Inventors: Leif Andersson, Goran Andersson, Michel Georges, Nadine Buys