Patents by Inventor Lene Teuber

Lene Teuber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
    Patent number: 11254681
    Abstract: Disclosed are compounds active towards nuclear receptors, pharmaceutical compositions containing the compounds and use of the compounds in therapy.
    Type: Grant
    Filed: May 11, 2020
    Date of Patent: February 22, 2022
    Assignee: NUEVOLUTION A/S
    Inventors: Sanne Schrøder Glad, Niels Grøn Nørager, Ian Sarvary, Alex Haahr Gouliaev, Lene Teuber, Luigi Piero Stasi
  • OPTIONALLY FUSED HETEROCYCLYL- SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES
    Publication number: 20200392140
    Abstract: Disclosed are compounds active towards nuclear receptors, pharmaceutical compositions containing the compounds and use of the compounds in therapy.
    Type: Application
    Filed: May 11, 2020
    Publication date: December 17, 2020
    Inventors: Sanne Schrøder Glad, Niels Grøn Nørager, Ian Sarvary, Alex Haahr Gouliaev, Lene Teuber, Luigi Piero Stasi
  • Compounds active towards bromodomains
    Patent number: 10752640
    Abstract: Disclosed are compounds towards bromodomains, pharmaceutical compositions containing the compounds and use of the compounds in therapy.
    Type: Grant
    Filed: July 29, 2015
    Date of Patent: August 25, 2020
    Assignee: NUEVOLUTION A/S
    Inventors: Jimmi Gerner Seitzberg, Tine Titilola Akinlemnu Kronborg, Visnja Poljak, Gitte Friberg, Lene Teuber
  • Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
    Patent number: 10689383
    Abstract: Disclosed are compounds of Formula I, which are active toward nuclear receptors such as nuclear retinoic acid receptor-related orphan receptors (RORs), pharmaceutical compositions containing the compounds of Formula I, and methods of treating inflammatory, metabolic, oncologic and autoimmune diseases or disorders using the of the compounds Formula I in therapy.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: June 23, 2020
    Assignee: NUEVOLUTION A/S
    Inventors: Sanne Schrøder Glad, Kim Birkebæk Jensen, Niels Grøn Nørager, Ian Sarvary, Mikkel Vestergaard, Alex Haahr Gouliaev, Lene Teuber, Luigi Piero Stasi
  • Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases
    Patent number: 10683293
    Abstract: Disclosed are compounds active towards nuclear receptors, pharmaceutical compositions containing the compounds and use of the compounds in therapy.
    Type: Grant
    Filed: July 31, 2015
    Date of Patent: June 16, 2020
    Assignee: NUEVOLUTION A/S
    Inventors: Sanne Schrøder Glad, Niels Grøn Nørager, Ian Sarvary, Alex Haahr Gouliaev, Lene Teuber, Luigi Piero Stasi
  • COMPOUNDS ACTIVE TOWARDS BROMODOMAINS
    Publication number: 20170349607
    Abstract: Disclosed are compounds towards bromodomains, pharmaceutical compositions containing the compounds and use of the compounds in therapy.
    Type: Application
    Filed: July 29, 2015
    Publication date: December 7, 2017
    Inventors: Jimmi Gerner SEITZBERG, Tine Titilola Akinlemnu KRONBORG, Visnja POLJAK, Gitte FRIBERG, Lene TEUBER
  • OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES
    Publication number: 20170342074
    Abstract: Disclosed are compounds active towards nuclear receptors, pharmaceutical compositions containing the compounds and use of the compounds in therapy.
    Type: Application
    Filed: July 31, 2015
    Publication date: November 30, 2017
    Inventors: Sanne Schrøder GLAD, Niels Grøn NØRAGER, Ian SARVARY, Alex Haahr GOULIAEV, Lene TEUBER, Luigi Piero STASI
  • OPTIONALLY FUSED HETEROCYCLYL-SUBSTITUTED DERIVATIVES OF PYRIMIDINE USEFUL FOR THE TREATMENT OF INFLAMMATORY, METABOLIC, ONCOLOGIC AND AUTOIMMUNE DISEASES
    Publication number: 20170327503
    Abstract: Disclosed are compounds active towards nuclear receptors, pharmaceutical compositions containing the compounds and use of the compounds in therapy.
    Type: Application
    Filed: July 31, 2015
    Publication date: November 16, 2017
    Inventors: Sanne Schrøder GLAD, Kim Birkebæk JENSEN, Niels Grøn NØRAGER, Ian SARVARY, Mikkel VESTERGAARD, Alex Haahr GOULIAEV, Lene TEUBER, Luigi Piero STASI
  • Benzimidazole derivatives and their use for modulating the GABAreceptor complex
    Patent number: 8288418
    Abstract: Benzimidazole derivatives, pharmaceutical compositions containing them, and methods of treatment therewith involving modulation of the GABAA receptor complex. The compounds have the formula I: wherein the variables are as described in the specification. The compounds are useful in the treatment of central nervous system diseases and disorders which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: October 16, 2012
    Assignee: Neurosearch A/S
    Inventors: Janus S. Larsen, Lene Teuber, Philip K. Ahring, Elsebet Østergaard Nielsen, Naheed Mirza
  • Potassium channel modulating agents and their medical use
    Patent number: 8252806
    Abstract: This invention relates to novel potassium channel modulating agents, and their use in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: March 13, 2006
    Date of Patent: August 28, 2012
    Assignee: Neurosearch A/S
    Inventors: Birgitte L. Eriksen, Lene Teuber, Charlotte Hougaard, Ulrik Svane Sørensen
  • Indazolyl derivatives useful as potassium channel modulating agents
    Patent number: 8222262
    Abstract: Potassium channel modulating agents of Formula Ia or Ib and enantiomers and mixtures enantiomers and N-oxides thereof, and pharmaceutically acceptable salts thereof, and their use in the preparation of pharmaceutical compositions. Also, pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels, e.g.
    Type: Grant
    Filed: October 3, 2007
    Date of Patent: July 17, 2012
    Assignee: Neurosearch A/S
    Inventors: Birgitte L. Eriksen, Ulrik Svane Sørensen, Charlotte Hougaard, Lene Teuber, Dan Peters, Palle Christophersen, Tina Holm Johansen
  • Guanidine derivatives and their medical use
    Patent number: 8048877
    Abstract: This invention relates to novel guanidine derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: November 1, 2011
    Assignee: Neurosearch A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Palle Christophersen
  • 2-aminio-pyridine derivatives and their use as potassium channel modulators
    Patent number: 8039632
    Abstract: This invention relates to novel 2-amino-pyridine derivative useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: November 12, 2007
    Date of Patent: October 18, 2011
    Assignee: Neurosearch A/S
    Inventors: Ulrik Svane Sørensen, Birgitte L. Eriksen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Palle Christophersen
  • Imidazole derivatives for the treatment of anxiety and related diseases
    Patent number: 8030339
    Abstract: This invention relates to novel imidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Grant
    Filed: October 12, 2006
    Date of Patent: October 4, 2011
    Assignee: Neurosearch A/S
    Inventors: William Dalby Brown, Janus S. Larsen, Lene Teuber, David Tristram Brown, Philip K. Ahring, Naheed Mirza, Elsebet Østergaard Nielsen
  • PYRIDINYL-PYRIMIDINE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATING AGENTS
    Publication number: 20110144140
    Abstract: This invention relates to novel pyridinyl-pyrimidine derivatives and their use as potassium channel modulating agents. Moreover the invention is directed to pharmaceutical compositions useful for the treatment or alleviation of diseases or disorders associated with the activity of potassium channels.
    Type: Application
    Filed: September 6, 2007
    Publication date: June 16, 2011
    Inventors: Birgitte L. Eriksen, Ulrik Svane Sorensen, Charlotte Hougaard, Lene Teuber, Dan Peters, Falle Christophersen, Tina Holm Johansen
  • 2-(phenylamino) benzimidazole derivatives and their use as modulators of small-conductance calcium-activated potassium channels
    Patent number: 7960561
    Abstract: This invention relates to novel 2-(phenylamino)benzimidazole derivatives useful as modulators of small-conductance calcium-activated potassium channels (SK channels). In other aspects the invention relates to the use of these compounds in a method for therapy and to pharmaceutical compositions comprising the compounds of the invention.
    Type: Grant
    Filed: June 21, 2006
    Date of Patent: June 14, 2011
    Assignee: Neurosearch A/S
    Inventors: Ulrik Svane Sørensen, Lene Teuber, Dan Peters, Dorte Strøbæk, Tina Holm Johansen, Karin Sandager Nielsen, Palle Christophersen
  • BENZIMIDAZOLE DERIVATIVES AND THEIR USE FOR MODULATING THE GABAA RECEPTOR COMPLEX
    Publication number: 20110118259
    Abstract: This invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Application
    Filed: January 20, 2011
    Publication date: May 19, 2011
    Inventors: Janus S. Larsen, Lene Teuber, Philip K. Ahring, Elsebet Ostergaard Nielsen, Naheed Mirza
  • Imidazole derivatives and their use for modulating the GABAreceptor complex
    Patent number: 7939556
    Abstract: This invention relates to novel imidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Grant
    Filed: October 12, 2006
    Date of Patent: May 10, 2011
    Assignee: Neurosearch A/S
    Inventors: William Dalby Brown, Janus S. Larsen, Lene Teuber, David Tristram Brown, Philip K. Ahring, Naheed Mirza, Elsebet Østergaard Nielsen
  • Benzimidazole derivatives and their use for modulating the GABAreceptor complex
    Patent number: 7923464
    Abstract: This invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: April 12, 2011
    Assignee: Neurosearch A/S
    Inventors: Janus S. Larsen, Lene Teuber, Philip K. Ahring, Elsebet Østergaard Nielsen, Naheed Mirza
  • Benzimidazole derivatives and their use for modulating the GABAreceptor complex
    Patent number: 7902230
    Abstract: This invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Grant
    Filed: March 22, 2007
    Date of Patent: March 8, 2011
    Assignee: Neurosearch A/S
    Inventors: Janus S. Larsen, Lene Teuber, Philip K. Ahring, Elsebet Østergaard Nielsen, Naheed Mirza