Patents by Inventor Lene Teuber

Lene Teuber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Kcnq channel modulating compounds and their pharmaceutical use
    Publication number: 20060173058
    Abstract: This invention relates to novel compounds useful as modulators of the KCNQ channel, to pharmaceutical compositions comprising these compounds, and to methods of treatment herewith.
    Type: Application
    Filed: March 11, 2004
    Publication date: August 3, 2006
    Inventors: William Brown, Lene Teuber, Bjarne Dahl
  • Benzimidazole derivatives and their use for modulating the gabaa receptor complex
    Publication number: 20060148856
    Abstract: This invention relates to novel benzimidazole derivatives of formula (I), pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Application
    Filed: April 1, 2004
    Publication date: July 6, 2006
    Inventor: Lene Teuber
  • Benzimidazole derivatives and their use for modulating the gaba-a receptor complex
    Publication number: 20060069135
    Abstract: This invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.
    Type: Application
    Filed: April 1, 2004
    Publication date: March 30, 2006
    Inventors: Lene Teuber, Janus Larsen
  • Ion channel modulating agents
    Patent number: 7012146
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SK Ca, IK Ca and BK Ca channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, for methods of therapy, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: March 14, 2006
    Assignee: Poseidon Pharmaceuticals A/S
    Inventors: Bo Skaaning Jensen, Dorte Strobaek, Palle Christophersen, Lene Teuber, Jurgen Beyer
  • Use of isatin derivatives as ion channel activating agents
    Patent number: 6969729
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Grant
    Filed: October 16, 2002
    Date of Patent: November 29, 2005
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jørgensen, Philip K. Ahring, Palle Christophersen, Dorte Strøbaek, Lene Teuber, Søren Peter Olesen
  • Benzimidazole derivatives and pharmaceutical compositions comprising these compounds
    Patent number: 6936613
    Abstract: The present invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for inducing and maintaining anesthesia, sedation and muscle relaxation, as well as for combating febrile convulsions in children. The compounds of the invention may also be used by veterinarians.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: August 30, 2005
    Assignee: Neurosearch A/S
    Inventors: Lene Teuber, Frank Watjen
  • Potassium channel blocking agents
    Patent number: 6878701
    Abstract: Compounds of Formula I: wherein A and B are linking groups; R1, R2, R3 and R4 are defined moieties. An exemplary compound is: These compounds function as potassium channel blocking agents, and can be used in a wide variety of pharmaceutical compositions for the treatment of a wide variety of diseases.
    Type: Grant
    Filed: December 28, 2001
    Date of Patent: April 12, 2005
    Assignee: Neurosearch A/S
    Inventors: Lene Teuber, Soren Peter Olesen, Dorte Strobaek
  • Potassium channel modulators
    Publication number: 20050009816
    Abstract: This invention relates to novel compounds useful as potassium channel modulators. More specifically the invention provides chemical compounds useful as modulators of SKCa and/or IKCa channels.
    Type: Application
    Filed: January 6, 2003
    Publication date: January 13, 2005
    Inventors: Alex Gouliaev, Frank Slok, Lene Teuber, Joachim Demnitz
  • Ion channel modulating agents
    Patent number: 6759422
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: August 2, 2002
    Date of Patent: July 6, 2004
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds
    Publication number: 20040097570
    Abstract: The present invention relates to novel benzimidazole derivatives, pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABAA receptor complex, and in particular for inducing and maintaining anesthesia, sedation and muscle relaxation, as well as for combating febrile convulsions in children. The compounds of the invention may also be used by veterinarians.
    Type: Application
    Filed: July 15, 2003
    Publication date: May 20, 2004
    Applicant: NEUROSEARCH A/S
    Inventors: Lene Teuber, Frank Watjen
  • Technical field
    Patent number: 6710044
    Abstract: Chemical compounds of the formula as well as pharmaceutical compositions containing them and methods for their use in the treatment of disorders and diseases responsive to modulation of the GABAA receptor complex of the central nervous system, such disorders and diseases including anxiety, sleep disorders, anesthesia, memory disorders, and epilepsy and other convulsive disorders.
    Type: Grant
    Filed: November 20, 2002
    Date of Patent: March 23, 2004
    Assignee: NeuroSearch A/S
    Inventors: Lene Teuber, Frank Wätjen
  • Benzimidazolone-, benzoxazolone-, or benzothiazolone derivatives as ion channel modulating agents
    Publication number: 20040029937
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Application
    Filed: July 1, 2003
    Publication date: February 12, 2004
    Applicant: NEUROSEARCH A/S.
    Inventors: Lene Teuber, Palle Christophersen, Dorte Strobaek, Bo Skaaning Jensen
  • Benzimidazole derivatives and pharmaceutical compositions comprising these compounds
    Patent number: 6649609
    Abstract: The present invention relates to novel 1-phenylbenzimidazole derivatives having particular alkoxycarbonyl substituents in the 5-position of the benz ring and having particular cyclic substituents in the meta-position of the phenyl ring, as well as to pharmaceutical compositions containing these compounds and to methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of GABAA receptor complex, and in particular for inducing and maintaining anaesthesia, sedation, and muscle relaxation, as well as for combating febrile convulsions in children. The compounds of the invention may also be used by veterinarians.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: November 18, 2003
    Assignee: Neurosearch A/S
    Inventors: Lene Teuber, Frank Watjen
  • Ion channel modulating agents comprising novel benzimidazolone derivatives
    Patent number: 6624186
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments, and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Grant
    Filed: May 15, 2001
    Date of Patent: September 23, 2003
    Assignee: Neurosearch A/S
    Inventors: Lene Teuber, Palle Christophersen, Dorte Strobaek, Bo Skaaning Jensen
  • Technical field
    Publication number: 20030166638
    Abstract: Chemical compounds of the formula 1
    Type: Application
    Filed: November 20, 2002
    Publication date: September 4, 2003
    Applicant: NeuroSearch A/S
    Inventors: Lene Teuber, Frank Watjen
  • Use of isatin derivatives as ion channel activating agents
    Publication number: 20030114513
    Abstract: The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SKCa and IKCa channels. In further aspects, the present invention relates to the use of these SK/IK channel activating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK channel activating agents.
    Type: Application
    Filed: October 16, 2002
    Publication date: June 19, 2003
    Applicant: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Tino Dyhring Jorgensen, Philip K. Ahring, Palle Christophersen, Dorte Strobaek, Lene Teuber, Soren Peter Olesen
  • Bis(benzimidazole) derivatives serving as potassium blocking agents
    Patent number: 6569880
    Abstract: This invention relates to novel potassium channel blocking agents, and their use in the preparation of pharmaceutical compositions.
    Type: Grant
    Filed: February 28, 2002
    Date of Patent: May 27, 2003
    Assignee: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Søren Peter Olesen, Lene Teuber, Dan Peters, Dorte Strøbæk
  • Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds
    Publication number: 20030055055
    Abstract: The present invention relates to novel benzimidazole derivatives, pharmaceutical composition containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABA receptor complex, and in particular for inducing and maintaining anesthesia, sedation and muscle relaxation, as well as for combating febrile convulsions in children. The compounds of the invention may also be used by veterinarians.
    Type: Application
    Filed: December 12, 2001
    Publication date: March 20, 2003
    Inventors: Lene Teuber, Frank Watjen
  • Use of ion channel modulating agents
    Patent number: 6525043
    Abstract: The present invention relates to the use of a particular class of chemical compounds as modulators of SKCa, IKCa and BKCa channels, and to pharmaceutical compositions comprising the SK/IK/BK channel modulating agents.
    Type: Grant
    Filed: October 25, 2001
    Date of Patent: February 25, 2003
    Assignee: NeuroSearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen
  • Ion channel modulating agents
    Publication number: 20030008906
    Abstract: The present invention relates to ion channel modulating agents. More particularly, the present invention relates to a particular class of chemical compounds represented by general formula (I) that has proven useful as modulators of SKCa, IKCa and BKCa channels. In further aspects, the present invention relates to the use of these SK/IK/BK channel modulating agents for the manufacture of medicaments and pharmaceutical compositions comprising the SK/IK/BK channel modulating agents. The SK/IK/BK channel modulating agents of the invention are useful for the treatment or alleviation of diseases and conditions associated with the SK/IK/BK channels.
    Type: Application
    Filed: August 2, 2002
    Publication date: January 9, 2003
    Applicant: Neurosearch A/S
    Inventors: Bo Skaaning Jensen, Lene Teuber, Dorte Strobaek, Palle Christophersen, Soren Peter Olesen