Abstract: A method of maintaining a circuit card in a card rack and a circuit card rack system are disclosed. A card rack including a laterally oriented clamping slot is provided. The clamping slot is at least partially formed from a temperature-contractible material. A circuit card having a clamped side region is provided. At least a portion of the clamped side region is inserted into the clamping slot. A predetermined temperature differential is applied to the clamping slot to reduce a longitudinal dimension of at least a portion of the clamping slot. A compressive force is exerted on the portion of the clamped side region which is located longitudinally within the clamping slot, via thermal expansion of the clamping slot.

Abstract: The present invention concerns modified recombinant J-chain polypeptides, binding molecules, such as antibodies comprising the same, and their uses.

Abstract: A method of maintaining a circuit card in a card rack and a circuit card rack system are disclosed. A card rack including a laterally oriented clamping slot is provided. The clamping slot is at least partially formed from a temperature-contractible material. A circuit card having a clamped side region is provided. At least a portion of the clamped side region is inserted into the clamping slot. A predetermined temperature differential is applied to the clamping slot to reduce a longitudinal dimension of at least a portion of the clamping slot. A compressive force is exerted on the portion of the clamped side region which is located longitudinally within the clamping slot, via thermal expansion of the clamping slot.

Abstract: The present invention concerns binding molecules that comprise an IgM, IgA, IgG/IgM or IgG/IgA antibody with a J-chain modified to include an AD-ME-modulating moiety, and their uses.

Abstract: The present invention concerns modified recombinant J-chain polypeptides, binding molecules, such as antibodies, comprising the same, and their uses.

Abstract: The present invention concerns modified recombinant J-chain polypeptides, binding molecules, such as antibodies comprising the same, and their uses.

Abstract: The present invention concerns modified recombinant J-chain polypeptides, binding molecules, such as antibodies, comprising the same, and their uses.

Abstract: An apparatus for, and method of, providing a desired temperature-differential circuit card environment includes a plurality of card units. Each card unit comprises a first thermal plate having front and back first plate sides oriented in a lateral-longitudinal plane, the first thermal plate operating at a first plate temperature. A second thermal plate has front and back second plate sides oriented in the lateral-longitudinal plane, the second thermal plate operating at a second plate temperature. A coupler is oriented in the lateral-longitudinal plane and is connected to front and/or back first plate sides and to the front and/or back second plate sides to form a card unit. The card units are arranged in a transversely oriented stack with the front first and second plate sides of a second card unit being directly transversely adjacent the back first and second plate sides of the first card unit.

Abstract: A method of maintaining a circuit card in a card rack and a circuit card rack system are disclosed. A card rack including a laterally oriented clamping slot is provided. The clamping slot is at least partially formed from a temperature-contractible material. A circuit card having a clamped side region is provided. At least a portion of the clamped side region is inserted into the clamping slot. A predetermined temperature differential is applied to the clamping slot to reduce a longitudinal dimension of at least a portion of the clamping slot. A compressive force is exerted on the portion of the clamped side region which is located longitudinally within the clamping slot, via thermal expansion of the clamping slot.

Abstract: An apparatus for, and method of, providing a desired temperature-differential circuit card environment includes a plurality of card units. Each card unit comprises a first thermal plate having front and back first plate sides oriented in a lateral-longitudinal plane, the first thermal plate operating at a first plate temperature. A second thermal plate has front and back second plate sides oriented in the lateral-longitudinal plane, the second thermal plate operating at a second plate temperature. A coupler is oriented in the lateral-longitudinal plane and is connected to front and/or back first plate sides and to the front and/or back second plate sides to form a card unit. The card units are arranged in a transversely oriented stack with the front first and second plate sides of a second card unit being directly transversely adjacent the back first and second plate sides of the first card unit.

Abstract: A circuit card assembly includes a substrate having longitudinally spaced first and second substrate end edges and transversely spaced top and bottom substrate surfaces. The top and/or bottom substrate surface has first, second, and third substrate regions. The first substrate region is directly laterally adjacent the first substrate side edge. The third substrate region is directly laterally adjacent the second substrate side edge. The second substrate region is located between the first and third substrate regions. At least one circuit trace is located on the selected substrate surface. The portion of the circuit trace in the first substrate region is made of only a first material. The portion of the circuit trace in the third substrate region is made of only a second material. The portion of the circuit trace in the second substrate region is made of both the first and second materials.

Abstract: A circuit card assembly includes a substrate having longitudinally spaced first and second substrate end edges and transversely spaced top and bottom substrate surfaces. The top and/or bottom substrate surface has first, second, and third substrate regions. The first substrate region is directly laterally adjacent the first substrate side edge. The third substrate region is directly laterally adjacent the second substrate side edge. The second substrate region is located between the first and third substrate regions. At least one circuit trace is located on the selected substrate surface. The portion of the circuit trace in the first substrate region is made of only a first material. The portion of the circuit trace in the third substrate region is made of only a second material. The portion of the circuit trace in the second substrate region is made of both the first and second materials.

Abstract: The present invention concerns IgA multi-specific binding molecules. In particular, the invention concerns multi-specific, including bispecific, binding molecules comprising IgA heavy chain sequences, and methods for their preparation and use.

Abstract: In an automated data storage library, selective encryption for data stored or to be stored on removable media is provided. One or more encryption policies are established, each policy including a level of encryption, one or more encryption keys and the identity of one or more data cartridges. The encryption policies are stored in a policy table and the encryption keys are stored in a secure key server. A host requests access to a specified data cartridge and the cartridge is transported from a storage shelf in the library to a storage drive. Based on the identity of the specified cartridge, the corresponding encryption policy is selected from the table and the appropriate encryption key is obtained from the key server. The storage drive encrypts data in accordance with the key and stores the data on the media within the specified data cartridge.

Abstract: A system for evaluating the condition of a pantograph, the system comprising: a track-side pantograph monitoring station that captures one or more images of a pantograph, while a locomotive comprising the pantograph is in normal service; a station management system that analyzes one or more images captured at the monitoring site and determines the condition of the pantograph; and a user interface that controls the system and presents the results of the analysis to the user. A user may control the track-side monitoring station and station management system remotely.

Abstract: Apparatus and methods for cooling liquid coolant, such as nitrous oxide, to be delivered to a cryo-ablation device such as a balloon catheter. A hose or conduit in fluid communication with the ablation device includes an outer member and inner tubes. A first inner tube disposed within a lumen of the outer member carries liquid coolant to the ablation device. Another inner tube also disposed within the lumen carries liquid coolant and terminates within the lumen such that gaseous coolant derived from liquid coolant flowing through the second inner tube flows within the lumen to cool or chill the first inner tube and liquid coolant carried by the first inner tube to the ablation device.

Abstract: Provided are a method, system, and article of manufacture for rekeying encryption keys for removable storage media. A rekey request is received for a coupled removable storage media, wherein encryption on the coupled removable storage media uses a first key and wherein the rekey request indicates a second key. The first key and the second key are accessed in response to the rekey request. The first key is used to perform decryption for the coupled removable storage media and the second key is used to perform encryption for the coupled removable storage media.

Abstract: Write protection for data of a rewritable data storage cartridge having partitions is provided in certain circumstances by providing logical write protection; and in response to detection of an application issuing at least one partition-based command with respect to the rewritable data storage cartridge, the logical write protection is disabled with respect to the detected application. Thus, where the cartridge has a non-default index addressing location, in response to detection of an application issuing at least one command initially addressing a location other than the non-default index location, logical write protection is enabled with respect to the detected application; and if the non-default index location is addressed, the logical write protection is disabled.

Abstract: A method, system and a computer program product to increase the availability of an automated data storage library for accessing and storing data storage media are provided. Work requests received by an accessor controller of the library from a host computer are also received and stored by a work request tracking controller. The accessor controller converts the work request into commands necessary to direct an accessor to fulfill the work request, and then sends such commands to an accessor. Upon detection by the work request tracking controller that the so-directed accessor failed to conduct the command issued by the accessor controller, the work request tracking controller reconstructs the work request and sends it to an accessor controller.

Abstract: An approach for automatically sharing a tape drive in a heterogeneous computing environment that includes a first computer and second computer is presented. The first computer receives a message that includes a shared tape drive identifier, a source port identifier of the second computer, and a reservation status change for the tape drive. Based on the tape drive identifier, the first computer determines that the tape drive is connected to the first computer. The source port identifier is determined to not identify any host bus adapter installed in the first computer. In response to the first computer determining that the reservation status change indicates a reservation or a release of the tape drive for the second computer, the first computer sets the tape drive offline or online, respectively, in an application executing in the first computer.