Patents by Inventor Leonid M Litvak

Leonid M Litvak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240100342
    Abstract: Devices, systems, and techniques are described that use electric field imaging (often referred to as the sensed stimulation artifact representative of a delivered stimulus) as an informative feedback signal to provide closed loop control of electrical stimulation therapy. In some examples, the electric field imaging may be used in combination with other feedback signals, such as ECAP do monitor and adjust the delivered electrical stimulation therapy.
    Type: Application
    Filed: February 23, 2022
    Publication date: March 28, 2024
    Inventors: Jerel K. Mueller, Leonid M. Litvak, Vinod Sharma, Katelynn M. Johnson, Jiashu Li
  • Patent number: 11918411
    Abstract: An exemplary diagnostic system may be configured to direct an acoustic stimulation generator to apply acoustic stimulation to a recipient of a cochlear implant during an insertion procedure in which an electrode lead coupled to the cochlear implant is supposed to be inserted into a cochlea of the recipient, direct the cochlear implant to use an electrode on the electrode lead to record an evoked response signal that occurs within the recipient in response to the acoustic stimulation, detect an anomaly in the evoked response signal, and determine, based on the anomaly, that the electrode lead is being inserted into a vestibular canal instead of into the cochlea.
    Type: Grant
    Filed: November 4, 2020
    Date of Patent: March 5, 2024
    Assignee: Advanced Bionics AG
    Inventors: Kanthaiah Koka, Leonid M. Litvak
  • Patent number: 11904170
    Abstract: A system for selecting a sensitivity level for adjusting an intensity setting for therapy provided to a patient includes one or more processors and one or more processors coupled to the memory. The one or more processors are configured to receive an indication of an input to adjust an intensity setting related to the therapy provided to the patient and determine a sensitivity level for adjustment of the intensity setting based on an efficacy of the therapy provided to the patient. The one or more processors are further configured to determine an updated intensity level for the intensity setting based on the sensitivity level and the input to adjust the intensity setting and output an instruction to cause a medical device to provide the therapy at the updated intensity level.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: February 20, 2024
    Assignee: Medtronic, Inc.
    Inventors: Todd D. Zenisek, Touby A. Drew, Brian Andrew Smith, Juan G. Hincapie, Leonid M. Litvak
  • Publication number: 20240050742
    Abstract: Methods, systems, and devices are configured delivering one or more sequences of different pulse trains to a patient. For example, a system includes processing circuitry configured to control stimulation circuitry to deliver a sequence of a plurality of trains of electrical stimulation pulses, wherein each train of the plurality of trains of electrical stimulation pulses comprises respective pulses at least partially defined by a unique parameter variation pattern of a plurality of parameter variation patterns, and control the stimulation circuitry to repeatedly deliver the sequence of the plurality of trains of electrical stimulation pulses.
    Type: Application
    Filed: August 9, 2023
    Publication date: February 15, 2024
    Inventors: Lisa M. Jungbauer Nikolas, Sarah J. Offutt, Katie C. Bittner, Julia P. Slopsema, Thaddeus S. Brink, Leonid M. Litvak
  • Publication number: 20240009463
    Abstract: Examples for controlling electrical stimulation therapy are described. One example includes delivering a pulse train at a frequency to a patient, the pulse train comprising a plurality of first pulses at least partially interleaved with a plurality of second pulses, wherein the plurality of first pulses are configured to facilitate sensing elicited electrical signals, each pulse of the plurality of first pulses having an active first phase and active second phase. Each pulse of the plurality of second pulses may include an active first phase and a passive second phase. Additionally, or alternatively, the plurality of second pulses may alternate between a cathodic active first phase and an anodic active first phase according to a ratio. At least one pulse of the plurality' of second pulses may have an interphase interval that is longer than an interphase interval of at least one pulse of the plurality of first pulses.
    Type: Application
    Filed: December 22, 2021
    Publication date: January 11, 2024
    Applicant: Medtronic, Inc.
    Inventors: David A. Dinsmoor, Ricardo Vallejo, Abigail Lauren Skerker, Leonid M. Litvak, Kristin N. Hageman, Hank T. Bink
  • Publication number: 20240001125
    Abstract: Example devices and techniques for improving signal quality of a sensed evoked response signal include processing circuitry communicatively coupled to stimulation generation circuitry and sensing circuitry. The processing circuitry is configured to control the stimulation generation circuitry to generate a stimulation signal and receive from the sensing circuitry the sensed evoked response signal. The processing circuitry is configured to determine that a characteristic value of at least one of the artifact or the sensed evoked response signal meets a threshold and automatically change, based on the determination that the characteristic value of the at least one of an artifact in the sensed evoked response signal or the sensed evoked response signal meets the threshold, at least one sensing parameter.
    Type: Application
    Filed: June 26, 2023
    Publication date: January 4, 2024
    Inventors: Benjamin P. Isaacson, David A. Dinsmoor, Leonid M. Litvak, Kristin N. Hageman, Hank Bink
  • Publication number: 20230414946
    Abstract: Systems and methods for controlling and optimizing closed-loop neuromodulation therapies are provided. The system may include a pulse generator configured to generate an electrical signal that may be transmitted to a plurality of a electrodes. The plurality of electrodes may include at least one stimulating electrode and at least one recording electrode. The at least one stimulating electrode may be configured to stimulate an anatomical element based on the electrical signal and the at least one recording electrode configured to record a physiological response.
    Type: Application
    Filed: May 22, 2023
    Publication date: December 28, 2023
    Inventors: Andrew Jay Cleland, Todd D. Zenisek, Andrew L. Schmeling, Juan G. Hincapie, Leonid M. Litvak
  • Publication number: 20230381521
    Abstract: For example, a system includes stimulation generation circuitry configured to deliver a multiphasic stimulation pulse to the patient and sensing circuitry configured to sense a composite evoked compound action potential (ECAP) signal elicited by the multiphasic stimulation pulse. The system further includes processing circuitry electrically connected to the sensing circuitry and the stimulation generation circuitry, the processing circuitry being configured to control the stimulation generation circuitry to deliver the multiphasic stimulation pulse that comprises a first phase and a second phase and determine, based on the composite ECAP signal, a propagation characteristic for the composite ECAP signal that is elicited by the multiphasic stimulation pulse.
    Type: Application
    Filed: May 23, 2023
    Publication date: November 30, 2023
    Inventors: David A. Dinsmoor, Aleksandra P. Kharam, Leonid M. Litvak
  • Publication number: 20230364425
    Abstract: Processing circuitry of a system configured to determine a patient state based on sensed signals including posture and activity information and control delivery of electrical stimulation therapy to the patient via electrodes implanted proximal to target tissue of the patient. The sensed signals also include impedance measurement, and other bioelectrical signals, where sensing is interleaved with the electrical stimulation therapy. Responsive to determining the patient state, select an action, wherein the selected action comprises one or more of: store collected information, upload the collected information to an external computing device, and output an electronic signal comprising an alert.
    Type: Application
    Filed: April 21, 2023
    Publication date: November 16, 2023
    Inventors: Hank T. Bink, Erik J. Peterson, Jiashu Li, Vinod Sharma, Juan G. Hincapie, Eric J. Panken, Leonid M. Litvak, David A. Dinsmoor, Todd D. Zenisek, Andrew L. Schmeling, Andrew J. Cleland
  • Publication number: 20230364426
    Abstract: Processing circuitry for a medical system configured to determine posture and activity information of a patient and sense bioelectrical signals as well as receive information about the environment of the patient. The processing circuitry is configured to determine respiration activity of the patient based on the sensed signals and determine a degree of distress of the patient based on the sensed signals and the determined respiration activity. Responsive to determining the degree of distress, the processing circuitry is configured to output a command signal, which may adjust the output of stimulation circuitry configured to deliver electrical stimulation to a patient via a set of electrodes implanted proximal target tissue of the patient, upload the received information, cause the communication circuitry to send an electronic message comprising a notification of the degree of distress of the patient or take other actions.
    Type: Application
    Filed: April 21, 2023
    Publication date: November 16, 2023
    Inventors: Juan G. Hincapie, Eric J. Panken, Leonid M. Litvak, David A. Dinsmoor, Todd D. Zenisek, Andrew L. Schmeling, Andrew J. Cleland
  • Publication number: 20230364427
    Abstract: Processing circuitry for a medical system configured to sense bioelectrical signals and determine posture and activity information as well as information about the environment of the patient. The processing circuitry is also configured to control stimulation generation circuitry to deliver the electrical stimulation therapy, and interleaved with the electrical stimulation therapy, control the stimulation generation circuitry to output an impedance measurement signal. The processing circuitry is further configured to determine respiration of the patient based on the impedance. Responsive to determining the respiration of the patient, the processing circuitry may then determine a patient state based on the determined respiration, and the posture and activity information of the patient.
    Type: Application
    Filed: April 21, 2023
    Publication date: November 16, 2023
    Inventors: Hank T. Bink, Erik J. Peterson, Jiashu Li, Vinod Sharma, Juan G. Hincapie, Eric J. Panken, Leonid M. Litvak, David A. Dinsmoor, Todd D. Zenisek, Andrew L. Schmeling, Andrew J. Cleland
  • Publication number: 20230355965
    Abstract: System and methods for stimulating or blocking a nerve are provided. The system may include an implantable pulse generator configured to generate a current and an electrode device in communication with the implantable pulse generator and configured to surround the nerve. The electrode device may include a housing comprising an inner surface, a first edge, and a second edge opposite the first edge; at least one electrode disposed on the inner surface and configured to apply the current to the nerve; and at least one closure configured to couple the first edge to the second edge to form a seal.
    Type: Application
    Filed: April 6, 2023
    Publication date: November 9, 2023
    Inventors: Maneesh Shrivastav, ShaileshKumar V. Musley, Kanthaiah Koka, Steven M. Goetz, Suryakiran Vadrevu, Rebecca K. Gottlieb, David John Miller, Leonid M. Litvak
  • Publication number: 20230355980
    Abstract: Systems and methods for wirelessly providing therapy to one or more anatomical elements may comprise a first capsule and a second capsule. The first capsule may be configured to wirelessly transmit instructions to a second capsule and the second capsule may be configured to receive the wirelessly transmitted instructions. The first capsule may receive an activation signal and apply a first current to a first anatomical element. The first capsule may also wirelessly transmit a first set of instructions to the second capsule to cause the second capsule to apply a second current to a second anatomical element.
    Type: Application
    Filed: April 6, 2023
    Publication date: November 9, 2023
    Inventors: Maneesh Shrivastav, ShaileshKumar V. Musley, Kanthaiah Koka, Steven M. Goetz, Suryakiran Vadrevu, Rebecca K. Gottlieb, David John Miller, Leonid M. Litvak
  • Publication number: 20230355141
    Abstract: A system is provided herein for stimulating an anatomical element of a patient. For example, the system may include a device (e.g., an implantable pulse generator) and an electrode device electrically coupled to the device. In some examples, the device may be configured to generate a current that is to be applied to the anatomical element via the electrode device to stimulate the anatomical element as part of a therapy aimed at achieving or supporting glycemic control in the patient. Additionally, the current may be applied to the anatomical element based on a machine learning algorithm that uses inputs gathered for determining one or more characteristics for the current. Accordingly, the machine learning algorithm may be configured to determine the one or more characteristics for the current specific to the patient (e.g., to provide personalized therapy settings for the patient).
    Type: Application
    Filed: April 7, 2023
    Publication date: November 9, 2023
    Inventors: Maneesh Shrivastav, ShaileshKumar V. Musley, Kanthaiah Koka, Steven M. Goetz, Suryakiran Vadrevu, Rebecca K. Gottlieb, David John Miller, Leonid M. Litvak
  • Publication number: 20230355982
    Abstract: A system is provided herein for stimulating an anatomical element of a patient. For example, the system may include a device configured to generate a current (e.g., implantable pulse generator), a first electrode device configured to apply the current to the anatomical element, and a second electrode device configured to record one or more response measurements associated with applying the current to the anatomical element. In some examples, the one or more response measurements may be used to generate growth curves associated with applying the current to the anatomical element, where the growth curves can be used to adjust one or more parameters of the current. Additionally, the one or more response measurements may include an evoked compound action potential (eCAP) measurement, an electromyography (EMG) measurement, a glucose level measurement, or a combination thereof.
    Type: Application
    Filed: April 7, 2023
    Publication date: November 9, 2023
    Inventors: Maneesh Shrivastav, ShaileshKumar V. Musley, Kanthaiah Koka, Steven M. Goetz, Suryakiran Vadrevu, Rebecca K. Gottlieb, David John Miller, Leonid M. Litvak
  • Publication number: 20230355969
    Abstract: A system is provided herein for stimulating an anatomical element of a patient. For example, a device may be configured to generate a current, and an electrode device coupled to the device may be configured to apply the current to the anatomical element. Additionally, the system may include a user interface in communication with the implantable pulse generator, the electrode device, or both. In some examples, the user interface may include a first element that is configured to display information associated with the patient. Additionally, the user interface may include a second element that is configured to receive inputs for programming parameters of the current. The user interface may also include a third element that is configured to display diagnostic information associated with applying the current to the anatomical element.
    Type: Application
    Filed: April 7, 2023
    Publication date: November 9, 2023
    Inventors: Maneesh Shrivastav, ShaileshKumar V. Musley, Kanthaiah Koka, Steven M. Goetz, Suryakiran Vadrevu, Rebecca K. Gottlieb, David John Miller, Leonid M. Litvak
  • Publication number: 20230355975
    Abstract: A system is provided herein for stimulating an anatomical element of a patient to achieve glycemic control for the patient. In some examples, the system may include a device configured to generate a current and an electrode device electrically coupled to the device that includes a plurality of electrodes configured for placement on or around the anatomical element. The device may receive instructions to apply the current to the anatomical element via the plurality of electrodes of the electrode device. Additionally, the current may be applied using a first waveform of a plurality of waveforms that the device is capable of generating, where each of the plurality of waveforms comprise a substantially similar charge density. Additionally or alternatively, a system is provided that provides a pharmacological blockade at the anatomical element using a micropump that is configured to deliver a pharmacological agent to the anatomical element to achieve glycemic control.
    Type: Application
    Filed: April 6, 2023
    Publication date: November 9, 2023
    Inventors: Maneesh Shrivastav, ShaileshKumar V. Musley, Kanthaiah Koka, Steven M. Goetz, Suryakiran Vadrevu, Rebecca K. Gottlieb, David John Miller, Leonid M. Litvak
  • Publication number: 20230355977
    Abstract: A system is described that includes: a first sensor that measures a glycemic level of a patient; a second sensor that measures at least one of a protein level of the patient, a hormone level of the patient, and an activity level of the patient; a processor that receives inputs from the first sensor and inputs from the second sensor; and memory including data that, when executed by the processor, enables the processor to perform one or more functions. An example of such function(s) include: analyzing the inputs received from the first sensor and the second sensor; determining, based on the analysis, that an electrical treatment is to be applied to the patient, where the electrical treatment includes application of at least one electrical signal to a nervous system of the patient; and causing the electrical treatment to be applied to the nervous system of the patient.
    Type: Application
    Filed: April 7, 2023
    Publication date: November 9, 2023
    Inventors: Maneesh Shrivastav, ShaileshKumar V. Musley, Kanthaiah Koka, Steven M. Goetz, Suryakiran Vadrevu, Rebecca K. Gottlieb, David John Miller, Leonid M. Litvak
  • Publication number: 20230355987
    Abstract: Systems and methods for stimulating an anatomical element are provided. The system may comprise an implantable pulse generator configured to generate a current and an electrode device comprising a plurality of electrodes configured to apply the current to the anatomical element. Each of the plurality of electrodes may comprise at least one of an anode or a cathode. The electrode device may be customized by assigning each of the plurality of electrodes as at least one of an anode or a cathode and at least one of active or inactive. The current may be applied to the anatomical element in a predetermined pattern using the plurality of electrodes.
    Type: Application
    Filed: April 6, 2023
    Publication date: November 9, 2023
    Inventors: Maneesh Shrivastav, ShaileshKumar V. Musley, Kanthaiah Koka, Steven M. Goetz, Suryakiran Vadrevu, Rebecca K. Gottlieb, David John Miller, Leonid M. Litvak
  • Publication number: 20230355244
    Abstract: Systems and methods for mechanically blocking a nerve are provided. The system may comprise a blocking device configured to selectively compress the nerve. The system may also comprise a feedback mechanism configured to measure a response correlating to whether the nerve is blocked. When the blocking device compresses the nerve, a response from the feedback mechanism is received that correlates to the nerve being blocked or unblocked after a period of time.
    Type: Application
    Filed: April 6, 2023
    Publication date: November 9, 2023
    Inventors: Maneesh Shrivastav, ShaileshKumar V. Musley, Kanthaiah Koka, Steven M. Goetz, Suryakiran Vadrevu, Rebecca K. Gottlieb, David John Miller, Leonid M. Litvak