Patents by Inventor Leslie A. Williams

Leslie A. Williams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8561175
    Abstract: A prevention-based network auditing system includes a central compliance server providing a user interface allowing a user to schedule and configure a network audit. The configured audit is stored in an audit repository until its scheduled time. At such a time, the compliance server automatically invokes one or more audit servers to gather information about the network. The compliance server receives the gathered information and electronically applies a network policy to the information for determining compliance with the policy. A remediation task may be generated if the policy has been violated, and the task monitored until its completion.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: October 15, 2013
    Assignee: Preventsys, Inc.
    Inventors: John Leslie Williams, Brian Costello, John Patrick Ravenel, Stephen J. Ritter, John Pelly, M. Celeste Rutherford, John Payne
  • Patent number: 8552240
    Abstract: Process for producing propylene from a propanol feedstock A2 by reacting the propanol feedstock A2 in a vapor phase dehydration reactor wherein the propanol is convened at a temperature comprised between 160 and 270° C. and at a pressure of above 0.1 MPa but less than 4.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: October 8, 2013
    Assignee: BP Chemicals Limited
    Inventors: Craig Bailey, Leslie William Bolton, Benjamin Patrick Gracey, Michael Keith Lee, Stephen Roy Partington
  • Publication number: 20130164823
    Abstract: An immunogenic reagent which produces an immune response which is protective against Bacillus anthracis, said reagent comprising one or more polypeptides which together represent up to three domains of the full length Protective Antigen (PA) of B. anthracis or variants of these, and at least one of said domains comprises domain 1 or domain 4 of PA ro a variant thereof. The polypeptides of the immunogenic reagent as well as full length PA are produced by expression from E. coli. High yields of polypeptide are obtained using this method. Cells, vectors and nucleic acids used in the method are also described and claimed.
    Type: Application
    Filed: September 26, 2012
    Publication date: June 27, 2013
    Inventors: Ethel Diane Williamson, Julie Miller, Nicola Jane Walker, Leslie William James Baillie, Paula Thomson Holden, Helen Claire Flick-Smith, Helen Lisa Bullifent, Richard William Titball, Andrew William Topping
  • Patent number: 8440873
    Abstract: Process for producing mono-olefins(s) from a feedstock A containing ethanol and propanol, wherein ethanol and propanol are dehydrated into the corresponding same carbon number olefins. The process is performed by 1. reacting feedstock A in a vapor phase dehydration reactor wherein the ethanol and propanol alcohols are converted into a product stream B comprising ethylene, propylene, ethers, water and unconverted alcohols, 2. cooling the product stream B, 3. disengaging the cooled product stream B in a separation unit to give a first stream C containing ethylene, propylene and ethers, and a second product stream D containing water, ethers and unconverted alcohols, 4. feeding the product stream D to a dewatering column wherein the water stream F is separated from the ethers and unconverted alcohols stream E, 5. recycling the stream E into the dehydration reactor of step 1, and 6. cooling the product stream C.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: May 14, 2013
    Assignee: BP Chemicals Limited
    Inventors: Craig Bailey, Leslie William Bolton, Benjamin Patrick Gracey, Michael Keith Lee, Stephen Roy Partington
  • Patent number: 8426664
    Abstract: Process for producing ethylene from an ethanol feedstock A by (1) reacting the ethanol feedstock A in a vapor phase reactor wherein the ethanol is converted at a temperature between 160 and 270° C. and at a pressure of above 0.1 MPa but less than 4.5 MPa, into a product stream B containing ethylene, diethyl ethers, water and unconverted ethanol, (2) cooling the product stream B, (3) disengaging the cooled product stream B in a separation unit to give a first stream C containing ethylene and diethyl ethers, and a second product stream D containing water, diethyl ethers and unconverted ethanol, (4) feeding the product stream D to a dewatering unit wherein the water stream F is separated from the diethyl ethers and unconverted ethanol stream E, (5) recycling the stream E into the dehydration reactor of step 1, (6) cooling the product stream C, and (7) feeding the cooled product stream C to a purification unit wherein the diethyl ethers stream G is separated from the ethylene stream H.
    Type: Grant
    Filed: November 22, 2006
    Date of Patent: April 23, 2013
    Assignee: BP Chemicals Limited
    Inventors: Craig Bailey, Leslie William Bolton, Benjamin Patrick Gracey, Michael Keith Lee, Stephen Roy Partington
  • Publication number: 20130079323
    Abstract: Novel gyrase inhibitors and related compositions and methods are useful for impeding bacterial growth.
    Type: Application
    Filed: September 10, 2010
    Publication date: March 28, 2013
    Applicant: TRIUS THERAPEUTICS, INC.
    Inventors: Christopher J. Creighton, Leslie William Tari, Zhiyong Chen, Mark Hilgers, Thanh To Lam, Xiaoming Li, Michael Trzoss, Junhu Zhang, John Finn, Daniel Bensen
  • Patent number: 8367886
    Abstract: Process for producing alkene(s) from a feedstock containing at least one monohydric aliphatic paraffinic alcohol having from 2 to 5 carbon atoms. The process is carried out by 1 converting the monohydric aliphatic paraffinic alcohol(s) containing 2 to 5 carbon atoms in a reactive distillation column at elevated pressure and temperature into a heads stream having the corresponding same carbon number alkene(s) and ether(s), 2 separating the heads stream from step 1 into an ether(s) enriched stream and an alkene(s) enriched stream, 3 recycling at least part of the ether(s) enriched stream from step 2 as a reflux return to the reactive distillation column, 4 simultaneously separating the alkene(s) enriched stream from step 2 into alkene(s) and ether(s), and 5 recycling at least part of the separated ether(s) from step 4 into the reactive distillation column. An alkene(s) stream from step 4 is then recovered.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: February 5, 2013
    Assignee: BP Chemicals Limited
    Inventors: Benjamin Patrick Gracey, Leslie William Bolton
  • Patent number: 8313928
    Abstract: An immunogenic reagent which produces an immune response which is protective against Bacillus anthracis, said reagent comprising one or more polypeptides which together represent up to three domains of the full length Protective Antigen (PA) of B. anthracis or variants of these, and at least one of said domains comprises domain 1 or domain 4 of PA or a variant thereof. The polypeptides of the immunogenic reagent as well as full length PA are produced by expression from E. coli. High yields of polypeptide are obtained using this method. Cells, vectors and nucleic acids used in the method are also described and claimed.
    Type: Grant
    Filed: March 26, 2007
    Date of Patent: November 20, 2012
    Assignee: The Secretary of State for Defense
    Inventors: Ethel Diane Williamson, Julie Miller, Nicola Jane Walker, Leslie William James Baillie, Paula Thomson Holden, Helen Claire Flick-Smith, Helen Lisa Bullifent, Richard William Titball, Andrew William Topping
  • Publication number: 20120238751
    Abstract: Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.
    Type: Application
    Filed: March 14, 2012
    Publication date: September 20, 2012
    Applicant: TRIUS THERAPEUTICS, INC.
    Inventors: Daniel Bensen, Zhiyong Chen, John Finn, Thanh To Lam, Suk Joong Lee, Xiaoming Li, Douglas W. Phillipson, Leslie William Tari, Michael Trzoss, Junhu Zhang, Felice C. Lightstone, Toan B. Nguyen, Sergio E. Wong, Paul Aristoff, Michael Jung
  • Patent number: 8224891
    Abstract: An electronic game-based learning system capable of providing a game-based learning environment(s) to at least one user is described. The system having at least one host system capable of selectively providing video and output portions of a game-based learning environment(s) and at least one client system capable of selectively providing input portions to the host system such that the client system provides the user within an interactive game-based learning environment(s).
    Type: Grant
    Filed: June 12, 2008
    Date of Patent: July 17, 2012
    Assignee: The Board of Regents of the University of Oklahoma
    Inventors: Scott N. Wilson, Mary J. O'Hair, Jean L. Cate, Leslie A. Williams, Linda K. Atkinson
  • Publication number: 20120136192
    Abstract: A process for removing water from an ethylene stream comprising water, said process comprising: introducing an ethylene stream comprising water into, and circulating said ethylene stream through, a separation vessel; introducing a liquid diethyl ether stream into, and circulating said liquid diethyl ether stream through, the separation vessel, so that said liquid diethyl ether stream and said ethylene stream comprising water are brought into contact; recovering an ethylene stream having a reduced water content from the separation vessel; and optionally recovering a liquid diethyl ether stream having an increased water content from the separation vessel.
    Type: Application
    Filed: August 10, 2010
    Publication date: May 31, 2012
    Inventors: Leslie William Bolton, Benjamin Patrick Gracey, Michael Keith Lee
  • Publication number: 20120112769
    Abstract: A method is provided for determining timing points indicative of the passage of a blade in a turbine engine. The method comprises the steps of: providing a s first sensing coil proximate to a path of the blade, providing a second sensing coil proximate to the path of the blade, the second sensing coil spaced from the first sensing coil in a direction parallel to the path of the blade, and comparing a signal generated in the first sensing coil with a signal generated in the second sensing coil to derive a timing point indicative of the passage of the blade.
    Type: Application
    Filed: May 18, 2011
    Publication date: May 10, 2012
    Applicant: Weston Aerospace Limited
    Inventors: Anthony Palmer, Matthew Clifton-Welker, Leslie William Allen
  • Publication number: 20120085646
    Abstract: An improved method of separating a macromolecule by isoelectric focusing comprising subjecting the macromolecule to electrophoresis in an isoelectric-focusing medium including a substantially thiol-free reducing agent, preferably a trivalent phosphorous compound and more preferably tributyl phosphine, the improvement being the solubility and focusing of the macromolecule is enhanced compared to isoelectric focusing of the same macromolecule in a similar isoelectric-focusing medium containing a thiol-reducing agent.
    Type: Application
    Filed: September 6, 2011
    Publication date: April 12, 2012
    Inventors: Ben Herbert, Andrew Arthur Gooley, Keith Leslie Williams
  • Patent number: 8148589
    Abstract: Process for producing alkene(s) from a feedstock containing at least one monohydric aliphatic paraffinic primary (or secondary) alcohol(s), consisting of ethanol or propanol(s) or a mixture thereof. The process includes the steps of converting the monohydric aliphatic paraffinic primary (or secondary) alcohol(s) into the corresponding same carbon number alkene(s) in a reactive distillation column at elevated pressure and temperature so that the heads stream extracted from the top of the reactive distillation column comprises essentially the alkene(s), cooling the heads stream from the first step to a temperature sufficient to condense at least part of the alkene(s) with the highest boiling point, recycling at least part of the condensed alkene(s) from the second step back into the reactive distillation column, as a reflux return, and simultaneously recovering the remaining alkene(s).
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: April 3, 2012
    Assignee: BP Chemicals Limited
    Inventors: Benjamin Patrick Gracey, Leslie William Bolton
  • Publication number: 20120079106
    Abstract: A prevention-based network auditing system includes a plurality of heterogeneous information sources gathering information about the network. An audit server invokes the heterogeneous information sources via a uniform communications interface to gather information about the network, and converts the information gathered by the information sources into a normalized data format such as, for example, into XML (Extensible Markup Language). The converted information is then stored in an audit repository for security and regulatory policy assessment, network vulnerability analysis, report generation, and security improvement recommendations.
    Type: Application
    Filed: December 6, 2011
    Publication date: March 29, 2012
    Inventors: John Leslie Williams, Brian Costello, John Patrick Ravenel, Thomas Paul Walpole
  • Publication number: 20120079107
    Abstract: A prevention-based network auditing system includes a plurality of heterogeneous information sources gathering information about the network. An audit server invokes the heterogeneous information sources via a uniform communications interface to gather information about the network, and converts the information gathered by the information sources into a normalized data format such as, for example, into XML (Extensible Markup Language). The converted information is then stored in an audit repository for security and regulatory policy assessment, network vulnerability analysis, report generation, and security improvement recommendations.
    Type: Application
    Filed: December 6, 2011
    Publication date: March 29, 2012
    Inventors: John Leslie Williams, Brian Costello, John Patrick Ravenel, Thomas Paul Walpole
  • Patent number: 8105613
    Abstract: Spore coat-associated proteins from members of Bacillus genera, and in particular spore-coat associated protein N (CotN), have utilization as adjuvants in vaccine formulations. The vaccine formulations most likely contain a virulence factor of bacterial origin, which in the case of Bacillus genera is the protective antigen.
    Type: Grant
    Filed: March 10, 2006
    Date of Patent: January 31, 2012
    Assignee: The Secretary of State for Defence
    Inventors: Helen Claire Flick-Smith, James Edward Eyles, Emma Louise Waters, Nicola Jane Walker, Ethel Diane Williamson, Leslie William Baillie, Julie Miller
  • Patent number: 8091117
    Abstract: A prevention-based network auditing system includes a plurality of heterogeneous information sources gathering information about the network. An audit server invokes the heterogeneous information sources via a uniform communications interface to gather information about the network, and converts the information gathered by the information sources into a normalized data format such as, for example, into XML (Extensible Markup Language). The converted information is then stored in an audit repository for security and regulatory policy assessment, network vulnerability analysis, report generation, and security improvement recommendations.
    Type: Grant
    Filed: February 13, 2004
    Date of Patent: January 3, 2012
    Assignee: Preventsys, Inc.
    Inventors: John Leslie Williams, Brian Costello, John Patrick Ravenel, Thomas Paul Walpoie
  • Publication number: 20110281961
    Abstract: The present invention relates to an improved process for the conversion of carbon oxide(s) et hydrogen containing feedstocks to oxygen containing hydrocarbon compounds in the presence of a particulate catalyst. In particular, the present invention relates to an improved process for the conversion of carbon oxide(s) (CO et CO2) et hydrogen containing feedstocks, e.g. Synthesis gas or syngas, to alcohols in the presence of a particulate modified molybdenum sulphide based catalyst and/or a modified methanol based catalyst and/or a modified Fischer-Tropsch catalyst and/or a precious metal based catalyst (e.g. rhodium).
    Type: Application
    Filed: May 25, 2007
    Publication date: November 17, 2011
    Inventors: Leslie William Bolton, Benjamin Patrick Gracey
  • Publication number: 20110072979
    Abstract: A portable automatic beverage brewing drinking vessel comprising, an on/off button, a heating element, a receptacle for accepting infusible material, and a means for translating the receptacle through the liquid. The means for translating the receptacle through the liquid includes but is not limited to, an electric motor, and magnets or electromagnets. In one embodiment, a pump transfers the liquid through tubes to the receptacle. The brewing vessel is portable and provides a simple and automatic means for brewing a beverage that can be consumed directly from the vessel.
    Type: Application
    Filed: September 24, 2010
    Publication date: March 31, 2011
    Inventor: Leslie William Fogg, IV