Patents by Inventor Leslie Bell
Leslie Bell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11771658Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.Type: GrantFiled: December 9, 2021Date of Patent: October 3, 2023Assignee: Cerion, LLCInventor: Eric Leslie Bell
-
Publication number: 20220096392Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.Type: ApplicationFiled: December 9, 2021Publication date: March 31, 2022Applicant: Cerion, LLCInventor: Eric Leslie Bell
-
Publication number: 20200345650Abstract: A process for making nanoparticles of biocompatible materials, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Also, biocompatibe nanoparticles comprised of cerium oxide, ethyenediaminedisuccinic acid, and optionally citric acid. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.Type: ApplicationFiled: May 28, 2020Publication date: November 5, 2020Applicant: Cerion, LLCInventor: Eric Leslie Bell
-
Patent number: 10729717Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.Type: GrantFiled: May 7, 2018Date of Patent: August 4, 2020Assignee: Cerion Enterprises LLCInventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
-
Patent number: 10722474Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible, nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.Type: GrantFiled: January 20, 2016Date of Patent: July 28, 2020Assignee: Cerion, LLCInventor: Eric Leslie Bell
-
Publication number: 20180325832Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible, nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.Type: ApplicationFiled: January 20, 2016Publication date: November 15, 2018Applicant: Cerion, LLCInventor: Eric Leslie Bell
-
Publication number: 20180250333Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.Type: ApplicationFiled: May 7, 2018Publication date: September 6, 2018Applicant: CERION, LLCInventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
-
Patent number: 9962406Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.Type: GrantFiled: December 22, 2016Date of Patent: May 8, 2018Assignee: CERION, LLCInventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
-
Publication number: 20170100430Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.Type: ApplicationFiled: December 22, 2016Publication date: April 13, 2017Applicant: CERION, LLCInventors: KENNETH JOSEPH REED, WENDI ANN COSTANZO, JOSEPH SAMUEL ERLICHMAN, ERIC LESLIE BELL
-
Patent number: 9533007Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.Type: GrantFiled: April 20, 2015Date of Patent: January 3, 2017Assignee: CERION, LLCInventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
-
Publication number: 20150231174Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.Type: ApplicationFiled: April 20, 2015Publication date: August 20, 2015Applicant: CERION, LLCInventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
-
Patent number: 9034392Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.Type: GrantFiled: March 15, 2013Date of Patent: May 19, 2015Assignee: CERION, LLCInventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
-
Publication number: 20130337083Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.Type: ApplicationFiled: March 15, 2013Publication date: December 19, 2013Applicant: Cerion Enterprises, LLCInventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
-
Patent number: 6766056Abstract: Disclosed is method of detecting a predetermined mark (30) forming part of an image. A digitized form (48, 49) of the image (21) comprising a plurality of picture elements is provided and within a current region of the image a set of features is determined. The features typically comprise a dominant color feature (44) within the current region; and at least one moment feature (111) based on picture elements pertaining to the predetermined mark within the current region. Each determined feature is compared (113) with a corresponding predetermined feature (114) of the predetermined mark. Using the comparison, a confidence level for a detection of said predetermined mark within the current region calculated. Based on the confidence level, whether or not said predetermined mark is detected in the current region can then be determined.Type: GrantFiled: November 30, 1999Date of Patent: July 20, 2004Assignee: Canon Kabushiki KaishaInventors: Kai Huang, Yu-Ling Chen, Peter Leslie Bell, Michael John Webb, Yoong-Chert Foo
-
Patent number: 6664902Abstract: An apparatus includes a DCT unit for transforming blocks of pixels into respective blocks of transform coefficients, entropy encoders for encoding respective partitions of the DCT blocks where at least one partition comprises bit-plane data from each block of transform coefficients, and a scan output manager for storing the entropy encoded partitions in a buffer of fixed memory size. The manager manages the storing of the coded partitions in the buffer whereby during the storing of the coded partitions if it is determined the buffer is full, a coded least perceptually significant partition currently stored in the buffer is overwritten by data from a coded more perceptually significant partition.Type: GrantFiled: December 6, 2001Date of Patent: December 16, 2003Assignee: Canon Kabushiki KaishaInventors: James Philip Andrew, Timothy Merrick Long, Peter Leslie Bell, Kevin John Moore, James David Clark
-
Publication number: 20020131084Abstract: Apparatus 100 is disclosed that comprises a DCT unit 104 for transforming blocks of pixels into respective blocks of transform coefficients, entropy encoders 106(1), . . . 106(18) for encoding respective partitions of the DCT blocks where at least one partition comprises bit-plane data from each of the block of transform coefficients, a scan output manager 108 for storing the entropy encoded partitions in a buffer 110 of fixed memory size. The manager 108 manages the storing of the coded partitions in the buffer 110 whereby during the storing of the coded partitions if it is determined the buffer 110 is full, a coded least perceptually significant partition currently stored in the buffer 110 is overwritten by data from a coded more perceptually significant partition.Type: ApplicationFiled: December 6, 2001Publication date: September 19, 2002Inventors: James Philip Andrew, Timothy Merrick Long, Peter Leslie Bell, Kevin John Moore, James David Clark
-
Patent number: 6240457Abstract: A computer network operating in accordance with a management protocol such as SNMP modifies the protocol such that a request communication from a management agent can be a type specifying multiplicity of data items and has a first part which identifies the type of the request.Type: GrantFiled: December 3, 1998Date of Patent: May 29, 2001Assignee: 3Com TechnologiesInventor: Ernest Leslie Bell
-
Patent number: 5871957Abstract: Methods are provided for producing protein products in host cells and for selecting transformed cells comprising the step of transforming the host cell with a DNA molecule comprising a gene which complements a deficiency in the host cell. The host cell is s strain having a deficiency in a function necessary for normal cell growth. The gene in the DNA molecule, such as a plasmid, which complements the deficiency serves as a selection marker whereby the growth conditions for selection may comprise a conventional complex medium.Type: GrantFiled: August 22, 1994Date of Patent: February 16, 1999Assignee: ZymoGenetics, Inc.Inventors: Glenn H. Kawasaki, Leslie Bell
-
Patent number: 5792601Abstract: A radiation sensitive emulsion is disclosed containing iridium doped composite silver halide grains comprised of (a) host portions having an average aspect ratio of less than 1.3 and consisting essentially of monodisperse silver iodochloride grains containing from 0.05 to 3 mole percent iodide, based on total silver forming the host portions, with maximum iodide concentrations located nearer the surface of the host portions than their center and (b) epitaxially deposited portions containing the iridium dopant and silver bromide accounting for from 0.1 to 5 mole percent of total silver forming the composite grains.The emulsions are prepared by (a) first providing an emulsion containing grains which form the host portions of the grains and (b) modifying the performance properties of the host grains by a combination of silver bromide addition, iridium dopant incorporation and antifoggant addition, in which, prior to antifoggant addition, silver bromide in the amount of from 0.1 to 5.Type: GrantFiled: July 29, 1996Date of Patent: August 11, 1998Assignee: Eastman Kodak CompanyInventors: James Lawrence Edwards, Benjamin Teh-Kung Chen, Eric Leslie Bell, Roger Lok
-
Patent number: 5723292Abstract: Methods are provided for producing protein products in host cells and for selecting transformed cells comprising the step of transforming the host cell with a DNA molecule comprising a gene which complements a deficiency in the host cell. The host cell is s strain having a deficiency in a function necessary for normal cell growth. The gene in the DNA molecule, such as a plasmid, which complements the deficiency serves as a selection marker whereby the growth conditions for selection may comprise a conventional complex medium.Type: GrantFiled: June 7, 1995Date of Patent: March 3, 1998Assignee: ZymoGenetics, Inc.Inventors: Glenn H. Kawasaki, Leslie Bell, Meher Irani