Patents by Inventor Leslie Bell

Leslie Bell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable DNA constructs
    Patent number: 5527668
    Abstract: Methods are provided for producing protein products in host cells and for selecting transformed cells comprising the step of transforming the host cell with a DNA molecule comprising a gene which complements a deficiency in the host cell. The host cell is a strain having a deficiency in a function necessary for normal cell growth. The gene in the DNA molecule, such as a plasmid, which complements the deficiency serves as a selection marker whereby the growth conditions for selection may comprise a conventional complex medium.
    Type: Grant
    Filed: October 12, 1993
    Date of Patent: June 18, 1996
    Assignee: ZymoGenetics, Inc.
    Inventors: Glenn Kawasaki, Leslie Bell
  • Stable DNA constructs for expression of .alpha.-1 antitrypsin
    Patent number: 4931373
    Abstract: Methods are provided for producing .alpha.-1-antitrypsin in host cells and for selecting transformed cells comprising the step of transforming the host cell with a DNA molecule comprising a gene which complements a deficiency in the host cell. The host cell is a strain having a deficiency in a function necessary for normal cell growth. The gene in the DNA molecule, such as a plasmid, which complements the deficiency serves as a selectable marker whereby the growth conditions for selection may comprise a conventional complex medium.
    Type: Grant
    Filed: October 22, 1984
    Date of Patent: June 5, 1990
    Assignee: ZymoGenetics, Inc.
    Inventors: Glenn Kawasaki, Leslie Bell