Patents by Inventor Li Yu
Li Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250144867Abstract: A polygonal cluster includes a plurality of substantially parallel polymeric columns disposed inside an outermost polygonal perimeter of the polygonal cluster and extending along a thickness direction between opposing first and second major surfaces of the polygonal cluster; and a common first material substantially filling regions within the polygonal perimeter between the polymeric columns and across the thickness of the polygonal cluster, such that in a cross-section of the polygonal cluster in a plane substantially orthogonal to the thickness of the cluster, for at least each of a plurality of first polymeric columns in the plurality of polymeric columns disposed adjacent the perimeter of the cluster, the first polymeric column has a pear shape having a wider portion facing the perimeter and a narrower portion facing away from the perimeter.Type: ApplicationFiled: February 3, 2023Publication date: May 8, 2025Inventors: Andrew C. Clausen, Li Yu, Michael R. Berrigan, Samuel E. Marmon, Timothy J. Lindquist, William J. Kopecky
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Publication number: 20250143046Abstract: A light emitting diode package structure includes one or more lead frame units, a light emitting element, and an encapsulation unit that completely covers the light emitting element and partially covers the lead frame units. Each lead frame unit includes a chip-mounted portion, a first electrode portion, and a second electrode portion. The first and the second electrode portion extend along a first direction, and are disposed on two sides of the chip-mounted portion. Each lead frame unit further includes multiple first connecting portions extending from the chip-mounted portion along the first direction, and multiple second connecting portions formed by extension of the first and the second electrode portion along a second direction. The light emitting element is fixed to the chip-mounted portion and electrically connected to the electrode portions. A lead frame that includes the at least one lead frame unit is also provided.Type: ApplicationFiled: October 25, 2024Publication date: May 1, 2025Inventors: HSIN-HUI LIANG, CHENG-HONG SU, CHEN-HSIU LIN, CHIH-LI YU, CHENG-HAN WANG, SHENG-YUN WANG
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Patent number: 12285594Abstract: The invention provides a syringe for detecting pressure change. The syringe includes a barrel defining a reservoir for receiving a constituent, a piston movable within the reservoir and a plunger. The barrel further includes a proximal end and a distal end with an outlet, an engaging member with a pair of fingers formed on an outer periphery of the barrel and a rib extending from the outer periphery of the barrel and disposed proximally to the engaging member. The plunger includes a first plunger part, a second plunger part and a baseplate supporting the first and second plunger parts. The first plunger part is partially received by the reservoir and slidably engaged with the piston. The second plunger part further includes at least one stop ledge to which the fingers of the engaging member releasably latch, and the stop ledge formed on a periphery of the second plunger part, and a compartment for accommodating a first biasing member with first and second ends.Type: GrantFiled: April 21, 2020Date of Patent: April 29, 2025Inventors: Li-Yu Lin, Wen-Fu Luo
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Publication number: 20250132944Abstract: An automatically matching system for intelligent devices comprises an intelligent device, at least one sensor, and a matching device. The intelligent device executes an intelligent function and includes at least one input property. The at least one sensor comprises at least one output property and outputs a sensing value. The matching device is connected to the intelligent device and the at least one sensor to receive the at least one input property of the intelligent device and the at least one output property of at least one sensor. Wherein, the matching device makes the intelligent device and the at least one sensor in a group when the at least one input property matches the at least one output property. The intelligent device in the group is configured to execute and adjust the intelligent function according to the sensing value of the at least one sensor.Type: ApplicationFiled: December 5, 2023Publication date: April 24, 2025Inventor: LI YU
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Publication number: 20250127726Abstract: A method for preparing a migrasome by suppressing the cell volume-regulatory function and then produce a migrasome derived from the cell and a method for preparing a delivery system including a migrasome.Type: ApplicationFiled: December 26, 2024Publication date: April 24, 2025Applicant: BEIJING MIGRASOME THERAPEUTICS LIMITEDInventors: Li YU, Dongju WANG, Chen DAI, Moye JIA, Shuo WANG, Tianlun DING, Takami SHO, Yi ZHENG
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Patent number: 12264194Abstract: The present disclosure is directed to methods of treating subjects colonized with S aureus with an anti-alpha toxin antibody or antigen-binding fragment thereof. The methods can decrease the incidence of infection attendant to the presence of S. aureus in the subject.Type: GrantFiled: March 12, 2020Date of Patent: April 1, 2025Assignee: MedImmune, LLCInventors: Mark Esser, Alexey Ruzin, Hasan Jafri, Kathryn Shoemaker, Bret Sellman, Li Yu
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Patent number: 12259319Abstract: A gas sensing device for detecting a to-be-detected substance in a respiratory gas exhaled by a user includes a housing permitting entrance of the respiratory gas, and a sensing module disposed in the housing. The sensing module includes a light chamber permitting the respiratory gas to pass therethrough, a light source unit emitting light into the light chamber, first and second light sensing units outputting respectively first and second detected signals indicating first and second detected intensities respectively of first and second portions of the light whose wavelengths fall within first and second wavelength ranges, respectively, and a processing unit electrically connected to the first and second light sensing units and determining, based on the first and second detected signals, that the to-be-detected substance exists in the respiratory gas when a difference occurs in each of the first and second detected intensities over time.Type: GrantFiled: May 17, 2023Date of Patent: March 25, 2025Assignee: GODSMITH SENSOR INC.Inventors: Yu-Ren Huang, Li-Yu Wang, Ming-Chun Hsiao, Chun-Han Huang, Yu-Da Chiu
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Patent number: 12260161Abstract: A method for establishing a variation model related to circuit characteristics for performing circuit simulation includes: performing first, second, third, and fourth Monte Carlo simulation operations according to a first netlist file and predetermined process model data to generate a first, a second, a third, and a fourth performance simulation results, respectively, where the first netlist file is arranged to indicate a basic circuit in a circuit system; and execute a performance simulation results expansion procedure according to the first, the second, the third, and the fourth performance simulation results to generate a plurality of performance simulation results to establish the variation model, for performing the circuit simulation to generate at least one circuit simulation result according to one or more performance simulation results among the plurality of performance simulation results, where the number of the plurality of performance simulation results is greater than four.Type: GrantFiled: March 13, 2022Date of Patent: March 25, 2025Assignee: Realtek Semiconductor Corp.Inventors: Wei-Ming Huang, Szu-Ying Huang, Mei-Li Yu, Yu-Lan Lo
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Patent number: 12243966Abstract: A light-emitting device comprises a semiconductor stack emitting a light with a peak wavelength ?; and a light field adjustment layer formed on the semiconductor stack, wherein the light field adjustment layer comprises a plurality of first layers and a plurality of second layers alternately stacked on top of each other, the plurality of first layers each comprises a first optical thickness, and the plurality of second layers each comprises a second optical thickness.Type: GrantFiled: June 22, 2021Date of Patent: March 4, 2025Assignee: EPISTAR CORPORATIONInventors: Heng-Ying Cho, Li-Yu Shen, Chih-Hao Chen, Keng-Lin Chuang
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Patent number: 12239252Abstract: An artificial Christmas tree includes an elongated trunk extending between proximal and distal ends thereof. A base may support the trunk of the artificial tree in an upright position relative to floor. The proximal end of the trunk may be coupled to the base and the distal end of the trunk extending outwardly from the base. A plurality of frame sections may extend circumferentially around the trunk and being moveable in an axial direction relative to the trunk. Each frame section may extend longitudinally between axially spaced apart ends thereof and being connected with at least one other frame section, whereby axial movement of a given frame section along the trunk causes corresponding axial movement of each other frame section to which the given frame section is connected.Type: GrantFiled: October 20, 2022Date of Patent: March 4, 2025Assignee: BALSAM INTERNATIONAL UNLIMITED COMPANYInventors: Jonathan I. Kaplan, Ta-li Yu, David Jason Wilkins, Nathaniel C. Roland
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Patent number: 12221631Abstract: The present invention relates to the field of biomedicine, and in particular to an engineered migrasome, a method for preparing the engineered migrasome, a delivery system comprising the engineered migrasome, and a method for preparing the delivery system.Type: GrantFiled: July 13, 2023Date of Patent: February 11, 2025Assignee: BEIJING MIGRASOME THERAPEUTICS LIMITEDInventors: Li Yu, Dongju Wang, Chen Dai, Moye Jia, Shuo Wang, Tianlun Ding, Qiushi Zhong, Yi Zheng
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Patent number: 12224043Abstract: Methods for determining treatments for cancer patients are disclosed.Type: GrantFiled: September 13, 2023Date of Patent: February 11, 2025Assignee: MEDIMMUNE, LLCInventors: Li Yu, Harry Yang, Mohammed Dar, Lorin Roskos, Jean-Charles Soria, Charles Ferte, Wei Zhao, Aline Gendrin Brokmann, Jolyon Faria, Pralay Mukhopadhyay, Ikbel Achour
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Publication number: 20250048792Abstract: A light-emitting device including a semiconductor stack generating a first light, and a filter formed on the semiconductor stack, including a first surface facing the semiconductor stack and a second surface opposite to the first surface. The filter includes pairs of layers with different refractive indexes alternately stacked. A portion of the first light is transmitted by the filter. The light emitting device emits a second light including the portion of the first light, and the second light includes a first directional part with a first FWHM and a second directional part with a second FWHM smaller than the first FWHM. The first directional part has a first angle with a normal direction of the second surface in a range of 45-90 degrees and the second directional part having a second angle with the normal direction of the second surface in a range of 0-30 degrees.Type: ApplicationFiled: October 25, 2024Publication date: February 6, 2025Inventors: Heng-Ying CHO, Li-Yu SHEN, Yu-Yi HUNG, Chen OU, Li-Ming CHANG
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Patent number: 12215358Abstract: Provided is a Coxsackievirus A6 (CVA6) strain CVA6-KM-J33 and use thereof, and belongs to the technical field of biomedicine. The present invention provides a CVA6 strain CVA6-KM-J33, which belongs to a CVA6 virus. In the present invention, the strain CVA6-KM-J33 is susceptible to KMB17 cells and can achieve a relatively high titer. The strain has strong virulence, high pathogenicity and lethality to suckling mice, and desirable immunogenicity, and is a highly effective virus strain for CVA6 vaccine development. This strain can be used for immunogenicity evaluation or protective evaluation of CVA6 vaccine to improve the accuracy and reproducibility of vaccine immunogenicity evaluation. This strain can also be used to prepare animal models of Coxsackievirus (CV) infection, and exhibits desirable application prospects.Type: GrantFiled: May 3, 2024Date of Patent: February 4, 2025Assignee: INSTITUTE OF MEDICAL BIOLOGY, CAMSInventors: Longding Liu, Li Yu, Guorun Jiang, Dandan Li, Heng Zhao, Huiwen Zheng, Ying Zhang, Yun Liao, Haijing Shi, Xin Zhao, Heng Li
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Patent number: 12194917Abstract: A light-emitting device is provided. The light-emitting device includes a light-emitting diode, a reflective structure, and a package structure. The reflective structure includes a bottom surface and a lateral part. The light-emitting diode is disposed on the bottom surface. The lateral part is disposed surrounding the bottom surface and disposed on the bottom surface. The package structure is configured to package the light-emitting diode and the reflective structure. The package structure includes a first package part and a second package part. The first package part has a phosphorescent powder. An interface is between the first package part and the second package part. The interface is disposed below a top surface of the lateral part.Type: GrantFiled: January 20, 2022Date of Patent: January 14, 2025Assignee: Lite-On Technology CorporationInventors: Cheng-Han Wang, Cheng-Hong Su, Chih-Li Yu
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Publication number: 20250013814Abstract: A method of an integrated circuit chip, includes: calculating a first slope of distance-to-spatial relation under first design condition according to spatial distance difference between two circuit elements within integrated circuit chip and a spatial process variation under first design condition; calculating a second slope of the distance-to-spatial relation under a second design condition according to the spatial distance difference and a spatial process variation under second design condition; calculating a ratio coefficient and an exponential coefficient according to the first slope, the second slope, a global process variation under the first design condition, and a global process variation under the second design condition; calculating a third slope of the distance-to-spatial relation under a third design condition according to the ratio coefficient and the exponential coefficient; and estimating a spatial process variation under the third design condition according to the third slope and the spatial dType: ApplicationFiled: May 19, 2024Publication date: January 9, 2025Applicant: Realtek Semiconductor Corp.Inventors: Wei-Ming Huang, Mei-Li Yu, Yu-Lan Lo
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Publication number: 20240423516Abstract: A dressing system for sensing a presence of an analyte includes a first layer, and a second layer facing a first major surface of the first layer. The second layer has a second permeability to the analyte less than a first permeability of the first layer. The dressing system further includes a first fiber configured to deliver an excitation light. The dressing system further includes at least one sensor layer including a sensor material configured to receive the excitation light from the first fiber and emit an emitted light in response to the excitation light. The dressing system further includes a second fiber separate from the first fiber and configured to receive the emitted light from the at least one sensor layer.Type: ApplicationFiled: July 29, 2022Publication date: December 26, 2024Applicant: Solventum Intellectual Properties CompanyInventors: Li YU, Dawn V. MUYRES, Mark A. ROEHRIG, John A. WHEATLEY, Jason W. BJORK, Przemyslaw P. MARKOWICZ
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Patent number: 12166151Abstract: A light-emitting device, including: a semiconductor stack generating a first light; and a filter formed on the semiconductor stack, including a first surface facing the semiconductor stack and a second surface opposite to the first surface; and a transparent conductive layer formed on the semiconductor stack; wherein: the filter includes a plurality of first dielectric layers with a first refractive index and a plurality of second dielectric layers with a second refractive index alternately stacked, a portion of the first light is transmitted by the filter and extracted from the second surface, the light-emitting device has a beam angle in a range of 50 degrees to 110 degrees, and the filter comprises a light transmittance of more than 90% with respect to light incident at an incident angle in a range less than 10 degrees.Type: GrantFiled: July 30, 2021Date of Patent: December 10, 2024Assignee: EPISTAR CORPORATIONInventors: Heng-Ying Cho, Li-Yu Shen, Yu-Yi Hung, Chen Ou, Li-Ming Chang
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Publication number: 20240404611Abstract: A The memory device includes a memory array comprising a plurality of one-time-programmable (OTP) memory cells. Each of the plurality of OTP memory cells comprises: a select transistor; a diode; and a conductor fuse. The diode and the conductor fuse are coupled in series, with the select transistor coupled to a common node between the diode and the conductor fuse.Type: ApplicationFiled: June 2, 2023Publication date: December 5, 2024Inventors: Chrong Jung Lin, Ya-Chin King, Li-Yu Wang
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Publication number: 20240390438Abstract: The present disclosure provides a probiotics of PTA22 from rabbits, a nutritional composition for preparing food of rabbits and a composition for rabbits to degrade oxalic acid. Through this disclosure, the health of rabbits can be ensured and the resistance to pathogenic bacteria can be improved after rabbits consume the food containing PTA22. As well, the probiotic PTA22 can help rabbits reduce the risk of hypercalciuria and calculus.Type: ApplicationFiled: August 12, 2024Publication date: November 28, 2024Inventors: JYH HORNG SHYU, LI YU CHIANG, YU HSIN CHANG, CHING YU CHIU, PEI-JU WANG