Abstract: The present invention provides a writing implement, including a pen tube, a guiding element, a motion sensor, and a controller. An end portion of the pen tube is provided with a nib. The guiding element and the motion sensor are disposed on the pen tube, and the guiding element is controlled by the controller. In the process of writing, the motion sensor detects words and pencraft characteristics when a user holds the pen tube for writing, and the controller controls the guiding element to generate a guiding force to guide the words and pencraft characteristics when writing, to approach or be equal to words and pencraft characteristics prepared to be written. Therefore, the present invention may train a user to copy the handwriting of a master or actively guide the user to wield the pen by means of the writing implement.

Abstract: The present invention relates to a method for the synthesis of a halo olefin of formula (I) wherein Ha1, R1, R2, R3, R4, X and Y are as defined herein, or a salt thereof.

Abstract: An authenticating server is coupled to a blockchain network is configured to: (1) receive a transaction application data from a user, wherein the transaction application data includes a wallet data containing a wallet address data and a user's signature data; (2) check whether an amount of a cryptocurrency corresponding to the wallet address data on the blockchain network is sufficient to perform the transaction; and (3) when the amount of the cryptocurrency corresponding to the wallet address data on the blockchain network is sufficient to perform the transaction, transmit a multi-signature wallet transaction data to the blockchain network for validating a blockchain operation, and send a confirmation data of the transaction associated with the transaction application data to an opposing party of the transaction. The multi-signature wallet transaction data includes the wallet address data, the user's signature data and a signature date of the authenticating server.

Abstract: The present invention is directed to a process for preparing a compound of formula I-11 through multiple-step reactions:

Abstract: The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.

Abstract: The present invention is directed to Compounds of Formula (I) and salts thereof, wherein R1, R2, R3 and R4 are defined above herein. The present invention is also directed to uses of the compounds of Formula (I) to add phosphoramidate groups onto organic alcohols.

Abstract: Method for fabricating A packaging structure is provided. The packaging structure includes a base substrate including a solder pad body region and a trench region adjacent to and around the solder pad body region. The packaging structure includes a passivation layer on the base substrate and exposing the solder pad body region and the trench region. The packaging structure includes a main body solder pad on the solder pad body region of the base substrate, and one or more trenches on the trench region of the base substrate and between the passivation layer and the main body solder pad. The packaging structure includes a bonding conductive wire having one end connected to the main body solder pad.

Abstract: Disclosed is an optometry apparatus capable of measuring para-central defocus, comprising a diopter measurement module. The diopter measurement module comprises a first light source (1) emitting a first light beam. The optometry apparatus also comprises a scanning module for adjusting the position of a light spot formed on the retina by the first light beam. The scanning module comprises a first reflecting mirror (3) and a second reflecting mirror (5) rotatably positioned in sequence in the emergent optical path of the first light source (1). The rotation axis of the first reflecting mirror (3) and the rotation axis of the second reflecting mirror (5) form therebetween an angle greater than 0 degree and less than 180 degrees.

Abstract: An underwater propulsion apparatus includes a motor and a control system for controlling the motor. The control system includes a remote controller and a motor driving device, wirelessly communicating with the remote controller. The motor driving device includes a communication repeater module and a motor driving module. The communication repeater module is configured for detecting interruptions or non-receipt of a wireless signal transmitted by the remote controller. Wireless signals to the motor driving module are transmitted by the remote controller to the communication repeater module. The motor driving module is configured for receiving the wireless signal, and outputs a driving signal for driving the motor according to the wireless signal, the motor driving module shutting down when no signal is received.

Abstract: A packaging structure and a method for fabricating the packaging structure are provided. The packaging structure includes a base substrate including a solder pad body region and a trench region adjacent to and around the solder pad body region. The packaging structure also includes a passivation layer on a surface of the base substrate and exposing the solder pad body region and the trench region. In addition, the packaging structure includes a main body solder pad on the solder pad body region of the base substrate, and one or more trenches on the trench region of the base substrate and between the passivation layer and the main body solder pad. Further, the packaging structure includes a bonding conductive wire having one end connected to the main body solder pad.

Abstract: A rooting agent for woody plants cutting includes raw materials of: sodium naphthalene-1-acetate, naphthalene acetamide, catechol, vitamin C, oxadixyl-mancozeb, boric acid, white sugar and urea. The rooting agent of the present invention contains various beneficial substances and rich nutrients and is easy absorbing. The rooting agent is capable of effectively improving rooting rate of woody plants cutting, and plants which are difficult to root has a high rooting rate after applying the rooting agent.

Abstract: The present invention is directed to processes for preparing beta 3 agonists of Formula (I) and Formula (II) and their intermediates. The beta 3 agonists are useful in the treatment of certain disorders, including overactive bladder, urinary incontinence, and urinary urgency.

Abstract: Disclosed are capsid-mutated rAAV vectors and methods for their use in gene therapy, and particularly for use in delivering therapeutic transgenes to treat a variety of mammalian diseases and disorders, including dysfunctions and abnormal conditions of the human eye. VP3 capsid proteins comprising a modification of one or more of the surface-exposed tyrosine residues are disclosed, and in particular, VP3 capsid protein comprising tyrosine-to-phenylalanine mutations at positions corresponding to Y444F, Y500F, and Y730F of the wild-type AAV2 sequence. Also provided are rAAV virions and viral particles that comprise such a mutated AAV capsid protein and a nucleic acid molecule that expresses one or more selected therapeutic or reporter transgenes in one or more mammalian cells of interest. Advantageously, the capsid-mutated rAAV vectors and virions disclosed herein afford improved transduction efficiency in a variety of cells, tissues and organs of interest, when compared to their unmodified (i.e.

Abstract: A text deduplication method and apparatus, and a storage medium are provided. The method includes: obtaining a text set, the text set including a plurality of to-be-deduplicated texts; capturing, for each to-be-deduplicated text, a corresponding subtext string from the to-be-deduplicated text; and determining, in the text set, to-be-deduplicated texts having a same subtext string, to obtain text subsets. Each subtext string corresponds to a text subset, and each text subset includes one or more to-be-deduplicated texts that have the corresponding subtext string. The method also includes performing text deduplication processing on the text subset corresponding to each subtext string, to obtain a deduplicated text set corresponding to each subtext string; and obtaining, according to the deduplicated text set corresponding to each subtext string, a result text set of the text set after the deduplication.

Abstract: A hot-plate-welded water pipe includes a first water inlet pipe, a second water inlet pipe, a lateral pipe, all of a hollow cylinder shape, and a cover plate. The lateral pipe is connected to and in communication with the first water inlet pipe and second water inlet pipe, an opening is provided on a central portion of the lateral tube, and the opening protrudes from a surface of the lateral pipe. The cover plate is connected onto the opening, and the cover plate is welded onto the opening through hot-plate-welding. The first water inlet pipe, the second water inlet pipe, and the lateral pipe formed integrally into a body through injection molding.

Abstract: A smart household control method, apparatus and system.

Abstract: The present invention relates to a method for the synthesis of a halo olefin of formula (I) wherein Hal, R1, R2, R3, R4, X and Y are as defined herein, or a salt thereof.

Abstract: A method for assisting human-computer interaction and a computer-readable medium applied to a human-computer interaction auxiliary device connected with an executing device. The method includes: acquiring a first control instruction, and the first control instruction includes a voice control instruction and/or a text control instruction parsing the first control instruction, generating a corresponding second control instruction according to the first control instruction, and the second control instruction is a preset control instruction that can be parsed by at least one of the executing device, and searching for, according to the first control instruction, a target executing device corresponding to the first control instruction and sending the second control instruction to the target executing device corresponding to the first control instruction.

Abstract: A multi-function pull head comprises a valve seat, and that includes: a water input connector, an outer shell, a water output portion, a first function switching structure, a second function switching structure, and a water output panel. The water input connector is connected onto the outer shell through a thread structure, and two through holes are provided on the outer shell, for the first function switching structure and second function switching structure to pass through respectively. The water input connector is disposed on a top portion of the valve seat. The outer shell is disposed on a bottom portion of the water input connector, to protect the valve seat. The outer shell is engaged to the water input connector through an engaging ring. The water output portion is disposed at a lower portion of the valve seat.