Abstract: Embodiments of the present disclosure relate to a coupler, antenna module and electronic device. The coupler comprises a first substrate layer and a second substrate layer located below the first substrate layer. The coupler also comprises a first coupling line located on an upper surface of the first substrate layer and a second coupling line located on a lower surface of the second substrate layer. The coupler further comprises a first ground layer located between a lower surface of the first substrate layer and an upper surface of the second substrate layer, a plurality of hole groups being formed in the first ground layer and being geometrically designed such that an electromagnetic field of the first coupling line is coupled to the second coupling line through the plurality of hole groups. In this way, PCB space and size may be saved, RF performance may be improved, and PCB cost may be reduced.

Abstract: Aspects of the disclosure provide compounds, compositions, and methods for modulating the expression or activity of angiotensinogen (AGT). In some aspects, the compounds, compositions, and methods of the disclosure can be used to reduce the expression of AGT mRNA in a cell or animal. In some aspects, the compounds, compositions, and methods of the disclosure can be used to reduce the expression of AGT protein in a cell or animal.

Abstract: Disclosed is a turbine vane thermal barrier coating working condition simulation experiment test system, including: a working state simulation device, a service environment simulation device and a detection device. The working state simulation device is provided on one side of the turbine vane thermal barrier coating to be tested, is connected to the turbine vane thermal barrier coating to be tested, and is configured to simulate a high-speed rotation working state of the turbine vane thermal barrier coating to be tested. The service environment simulation device is provided on the other side of the turbine vane thermal barrier coating to be tested. The detection device is configured to detect damage generated when the turbine vane thermal barrier coating to be tested rotates at a high speed in the service environment.

Abstract: Disclosed are a compound as an inhibitor of complement factor D, and a pharmaceutical composition thereof and the use thereof. Specifically disclosed are a compound as represented by formula (I), a tautomer thereof, a stereoisomer thereof and a prodrug thereof, or a pharmaceutically acceptable salt of any one of the above-mentioned compounds, or a solvate of any one of the above-mentioned compounds. The compound has a good inhibitory activity on complement factor D, and has an excellent pharmacokinetic and pharmacodynamic activity.

Abstract: An example system can include a memory device and a processing device. The memory device can include a group of memory cells. The processing device can be coupled to the memory device. The processing device can be configured to determine a distance of a memory die from a center of a memory component. The processing device can be configured to perform a read disturb operation on the memory die based on the determined distance use a first voltage window for a set of memory cells of the group of memory cells during a first time period.

Abstract: The disclosure provides an optical imaging lens assembly, which sequentially includes from an object side to an image side along an optical axis: a first lens with a positive refractive power; a second lens with a refractive power; a third lens with a refractive power; a fourth lens with a refractive power; a fifth lens with a refractive power, an object-side surface thereof is a convex surface, and an image-side surface thereof is a concave surface; a sixth lens with a positive refractive power, an object-side surface thereof is a convex surface, and an image-side surface thereof is a concave surface; a seventh lens with a negative refractive power; wherein an on-axis distance TTL from an object-side surface of the first lens to an imaging surface and a half of a diagonal length ImgH of an effective pixel region on the imaging surface satisfy: TTL/ImgH<1.25.

Abstract: Backup and restore of client-managed tables and system-managed tables in a same database may be performed. A request to restore a database with both a client-managed table and system-managed table may be received. The request may specify a point in time to restore the database. A metadata volume for the database that describes both the client-managed table and the system-managed table may be restored and used to identify the volumes for both the client-managed table and shards of the system-managed table. Redo logs for each of the volumes may be used according to timestamps that are synchronized according to a time synchronization service to generate restored versions of the volumes for the client-managed table and the shards of the system-managed table from backup copies, which can then be made available for accessing the database.

Abstract: The present disclosure provides methods for the prevention and treatment of Langerhans cell sarcoma (LCS) and Langerhans cell histiocytosis (LCH) in a subject comprising administering an effective or therapeutically effective dose of a HDAC3 inhibitor to the subject in need thereof.

Abstract: Provided are new compositions and methods useful for the treatment, prevention, and potential cure of Alzheimer's Disease by disrupting the genomic locus of IL1LR1 gene including rs1921622 and/or other 574 sST2-associated genomic sites and/or 3?-UTR of sST2 gene/transcript.

Abstract: Provided are an inspection method, and an inspection system including: at least one ray source; a detector assembly and a conveying device. At least one ray source and the detector assembly may move in a traveling direction relative to the conveying device, so that the to-be-inspected object may enter an inspection region. When viewed along a central axis of the inspection region, at least one ray source may translate between scanning positions, and a translation distance of at least one ray source between two adjacent scanning positions is greater than a spacing between adjacent target spots of each ray source. When at least one ray source is located at one scanning position, at least one ray source and the detector assembly move in the traveling direction and at least one ray source emits X-rays. After moving a predetermined distance, at least one ray source translates to another scanning position.

Abstract: The present invention provides a method for integrating a nucleic acid analysis system and measuring at least one target nucleic acid in a sample. The integrated nucleic acid analysis system includes one DMF device, which includes a substrate, a cover plate, and an instrument for performing a series of operations including magnetic beads based nucleic acid extraction, purification, thermal amplification, and optical measurement of nucleic acids in samples in a DMF device. The nucleic acid extraction and purification are based on the magnetic bead method, which uses instruments to move magnetic beads in different functional areas of the digital microfluidic chip, such as lysis reservoirs, cleaning reservoirs, and elution reservoirs, etc. The present invention integrates sample processing and detection on the same microfluidic chip, and the entire process is automatically completed by the corresponding instrument.

Abstract: An optical element with a lanthanide compound layer in accordance with the present invention comprises: an optical substrate including a first surface; the lanthanide compound layer made of lanthanide compound and being disposed on the first surface, and the lanthanide compound layer including a second surface; and an optical film stack disposed on the second surface. With the design of the lanthanide compound layer, the optical element has a blocking effect. Therefore, during the cleaning process of the optical element, a large number of particles can be removed, while effectively suppressing the expansion and generation of pinhole defects, and maintaining the original performance of the optical element.

Abstract: Novel cyclic ?-AA peptides and methods of use thereof in modulating E3 activity are presented. Each novel compound is comprised of four ?-AA building blocks. It was found that in particular, compound P6 activated E6AP to stimulate self-ubiquitination of E6AP and E6AP-catalyzed substrate ubiquitination as well as enhance the ubiquitination of E6AP substrates in the cell and accelerate their degradation.

Abstract: A ray scanning apparatus, including: a conveying device for conveying an object under inspection to pass through a scanning area; a ray source assembly including a plurality of ray source modules arranged around the scanning area on an upper side of the conveying device and fixed in a plane perpendicular to a conveying direction of the object under inspection; and a detector assembly including a plurality of detector sets fixed in a plane perpendicular to the conveying direction of the object under inspection; the detector assembly is located between the ray source assembly and the scanning area in a direction perpendicular to the conveying direction of the object under inspection, the ray source assembly and the detector assembly are arranged to overlap at least partially in the conveying direction of the object under inspection, and the plurality of ray source modules are mounted and detached independently of each other.

Abstract: An inspection system, including: a carrying device; at least one ray source and a detector assembly. When the at least one ray source is located at one of scanning positions relative to the carrying device, the at least one ray source and the detector assembly are lifted or lowered along the rotation axis relative to the carrying device and the at least one ray source emits X-rays. After the at least one ray source and the detector assembly are lifted or lowered a predetermined distance relative to the carrying device, the at least one ray source rotates around the rotation axis relative to the carrying device to another one of scanning positions. The inspection system further reconstructs a three-dimensional scanning image of the object to be inspected based on detection data of the detector assembly.

Abstract: An example method of performing memory access operations comprises: receiving a request to perform a memory access operation; identifying a block family associated with a set of memory cells; determining, for each logical programming level of a plurality of logical programming levels, a corresponding default block family error avoidance (BFEA) threshold voltage offset value associated with the block family; determining a value of a data state metric associated with the set of memory cells; determining, for each logical programming level of a plurality of logical programming levels, a corresponding sub-BFEA threshold voltage offset value; and performing the memory access operation by applying, for each logical programming level of the plurality of logical programming levels, a combination of the default BFEA threshold voltage value, the sub-BFEA threshold voltage value, and a corresponding base voltage level.

Abstract: Disclosed are a device and method for fully enclosed and fully automatic dispensing of cells. The device includes a sample feeding module, a liquid replenishment module, and a liquid distribution module. By means of the device, cell dispensing can be performed under enclosed conditions, such that the risk of infection due to contact with an external environment is reduced. In addition, the survival rate of dispensed cells is ensured, and the degree of precision of cells obtained after dispensing is high, thereby improving the quality of the dispensed cells.

Abstract: A collaborative-manipulation robotic arm for kitchen waste and a working method thereof are provided. The robotic arm includes: a base, including a transverse first mounting seat and a second mounting seat connected to the first mounting seat and extending downward; a driving mechanism, disposed at an end of the first mounting seat away from the second mounting seat; a front guide claw, an upper end of the front guide claw being connected to the driving mechanism; a fixed blade, disposed on a side of the second mounting seat facing the front guide claw; and a retractable finger, disposed at a lower end on the side of the second mounting seat facing the front guide claw. The fixed blade, the retractable finger, and the second mounting seat form a rear cutting claw.

Abstract: The present invention provides a device and method for analyzing quality indicators of a natural gas product and an application.

Abstract: The present disclosure discloses a method for constructing an efficient Bacillus subtilis promoter, and belongs to the technical field of gene engineering. According to the present disclosure, natural promoters identified by different sigma subunits are connected in series to obtain some double-series and triple-series promoters, the lengths of intervening sequences between core areas of the promoters are optimized on the basis of series connection of the promoters to further improve the activity of the promoters, finally, different RBS designs are performed on the promoters, and it is verified that this strategy can not only improve the compatibility between the promoters and other gene expression regulating and controlling elements, but also controllably regulate the expression of exogenous genes.