Patents by Inventor Liang Yu

Liang Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7502634
    Abstract: A high-density information presentation is provided on a space-constrained display device by associating individual display indications with user-definable states. For example, using a portion of a space-constrained display of a mobile phone, pager personal digital assistant, or other portable device, one or more external states may be presented as a simple graphical or character indication that corresponds, in a user-defined way, to the external state or states. In general, implementations allow monitoring and access of a large amount of data on a space-constrained display device. Usability problems associated with traditional systems that split data access and navigation over paged small screens are generally avoided.
    Type: Grant
    Filed: July 31, 2006
    Date of Patent: March 10, 2009
    Assignee: Versata Development Group, Inc.
    Inventor: Liang-Yu Chi
  • Publication number: 20090062510
    Abstract: Human chemotactic cytokine I polypeptides and DNA (RNA) encoding such chemotactic cytokines and a procedure for producing such polypeptides by recombinant techniques is disclosed. Also disclosed are methods for utilizing such chemotactic cytokines for the treatment of leukemia, tumors, chronic infections, auto-immune disease, fibrotic disorders, wound healing and psoriasis. Antagonists against such chemotactic cytokines and their use as a therapeutic to treat rheumatoid arthritis, auto-immune and chronic and acute inflammatory and infective diseases, allergic reactions, prostaglandin-independent fever and bone marrow failure are also disclosed. Also disclosed are diagnostic assays for detecting diseases related to mutations in the nucleic acid sequences and altered concentrations of the polypeptides. Also disclosed are diagnostic assays for detecting mutations in the polynucleotides encoding the chemotactic cytokines and for detecting altered levels of the polypeptide in a host.
    Type: Application
    Filed: April 19, 2007
    Publication date: March 5, 2009
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Guo-Liang Yu, Pedro Alfonso, Reiner L. Gentz, Jeffrey Y. Su
  • Publication number: 20090011983
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: May 8, 2007
    Publication date: January 8, 2009
    Applicant: Human Genome Sciences, Inc.
    Inventors: Steven M. Ruben, Craig A. Rosen, Daniel R. Soppet, Kenneth C. Carter, Daniel P. Bednarik, Gregory A. Endress, Guo-Liang Yu, Jian Ni, Ping Feng, Paul E. Young, John M. Greene, Ann M. Ferrie, D. Roxanne Duan, Jing-Shan Hu, Kimberly A. Florence, Henrik S. Olsen, Carrie L. Fischer, Reinhard Ebner, Laurie A. Brewer, Paul A. Moore, Yanggu Shi, David W. LaFleur, Yi Li, Zhizhen Zeng, Hla Kyaw
  • Publication number: 20090005301
    Abstract: The present invention relates to novel human secreted proteins and isolated nucleic acids containing the coding regions of the genes encoding such proteins. Also provided are vectors, host cells, antibodies, and recombinant methods for producing human secreted proteins. The invention further relates to diagnostic and therapeutic methods useful for diagnosing and treating diseases, disorders, and/or conditions related to these novel human secreted proteins.
    Type: Application
    Filed: June 7, 2007
    Publication date: January 1, 2009
    Applicant: Human Genome Sciences, Inc.
    Inventors: Jian Ni, Reinhard Ebner, David W. LaFleur, Paul A. Moore, Henrik S. Olsen, Craig A. Rosen, Steven M. Ruben, Daniel R. Soppet, Paul E. Young, Yanggu Shi, Kimberly A. Florence, Ying-Fei Wei, Charles Florence, Jing-Shan Hu, Yi Li, Hla Kyaw, Carrie L. Fischer, Ann M. Ferrie, Ping Fan, Ping Feng, Gregory A. Endress, Patrick J. Dillon, Kenneth C. Carter, Laurie A. Brewer, Guo-Liang Yu, Zhizhen Zeng, John M. Greene
  • Publication number: 20090000529
    Abstract: A glass table comprises a glass table plate, a retainer including a first side to cohere to the glass table plate and a second side, with a compartment defined in the interior of the second side and a fixed block disposed in the compartment, a table leg including a first end coupled to the second side of the retainer and a second end placed on the ground, with a receiving hole defined in the first end thereof and receiving the fixed block, and a fixed element inserted through the first end of the table leg and engaging with the fixed block of the retainer as to fix the table leg to the glass table.
    Type: Application
    Filed: January 31, 2008
    Publication date: January 1, 2009
    Inventor: Liang-Yu Cheng
  • Publication number: 20080313359
    Abstract: In accordance with an embodiment of the present invention, an assistance mechanism tracks a plurality of time intervals between a plurality of input events. Each input event of said plurality of input events is generated by a user physically manipulating an input device at a client. Based on the plurality of time intervals, the assistance mechanism dynamically determines a threshold period. Then the assistance mechanism determines whether a subsequent input event has been generated within said threshold period. In response to determining that an input event has not been generated within said threshold period, the assistance mechanism may cause information to be displayed at the client.
    Type: Application
    Filed: June 18, 2007
    Publication date: December 18, 2008
    Inventors: Liang-Yu Chi, Julien F. Lecomte
  • Patent number: 7462697
    Abstract: The invention provides a method for identifying positions of an antibody that can be modified without significantly reducing the binding activity of the antibody. In many embodiments, the method involves identifying a substitutable position in a parent antibody by comparing its amino acid sequence to the amino acid sequences of a number of related antibodies that each bind to the same antigen as the parent antibody. The amino acid at the substitutable position may be substituted for a different amino acid without significantly affecting the activity of the antibody. The subject methods may be employed to change the amino acid sequence of a CDR without significantly reducing the affinity of the antibody of the antibody, in humanization methods, or in other antibody engineering methods. The invention finds use in a variety of therapeutic, diagnostic and research applications.
    Type: Grant
    Filed: November 8, 2004
    Date of Patent: December 9, 2008
    Assignee: Epitomics, Inc.
    Inventors: Fernando Jose Rebelo Do Couto, Kristin B. Hendricks, S. Ellen Wallace, Guo-Liang Yu
  • Publication number: 20080297521
    Abstract: The present invention is directed towards systems and methods for dynamically modifying the appearance of a resource based on skins. The method of the present invention comprises building a user skin library based upon user selected skins and receiving requests to change the appearance of a resource from a user. Upon receiving a request, the present invention dynamically updates the appearance of a resource based upon a selected skin.
    Type: Application
    Filed: May 31, 2007
    Publication date: December 4, 2008
    Inventors: Liang-Yu Chi, Ashley Hall
  • Publication number: 20080301573
    Abstract: The present invention relates to systems and methods for providing content items containing components utilizing focus indication focus indication. The method according to one embodiment comprises receiving a request from a client by a content delivery network for a resource that comprises a plurality of resources. The plurality of resources are then concatenated at the content delivery network to generate a concatenated resource and propagated to the client through the content delivery network.
    Type: Application
    Filed: May 30, 2007
    Publication date: December 4, 2008
    Inventor: Liang-Yu Chi
  • Publication number: 20080301113
    Abstract: The present invention relates to providing vector terms for use in formulating search requests in response to a user query. The method according to one embodiment comprises receiving a search query from a client and identifying links to one or more content items corresponding to the search query. One or more term vectors are then generated corresponding to the content items and one or more vector terms are selected from the term vectors. The links to the one or more content items and selected vector terms are combined to form a final result page.
    Type: Application
    Filed: May 31, 2007
    Publication date: December 4, 2008
    Inventors: Liang-Yu Chi, Swati Raju, Ashley Hall, Peter Anick
  • Publication number: 20080254473
    Abstract: This invention provides a method for predicting the post-treatment survival prospect of a cancer patient based on the expression level(s) of microRNAs hsa-miR137, hsa-miR372, hsa-miR182*, hsa-miR221, and hsa-let-7a in that cancer patient.
    Type: Application
    Filed: April 9, 2008
    Publication date: October 16, 2008
    Inventors: Jian-Wei Chen, Sung-Liang Yu, Hsuan-Yu Chen, Gee-Chen Chang, Chih-Yi Chen, Pan-Chyr Yang
  • Publication number: 20080248046
    Abstract: The present invention relates to novel Death Domain Containing Receptor-5 (DR5) proteins which are members of the tumor necrosis factor (TNF) receptor family, and have now been shown to bind TRAIL. In particular, isolated nucleic acid molecules are provided encoding the human DR5 proteins. DR5 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying antagonists and antagonists of DR5 activity. The invention also relates to the treatment of diseases associated with reduced or increased levels of apoptosis using antibodies specific for DR5, which may be agonists and/or antagonists of DR5 activity.
    Type: Application
    Filed: January 18, 2008
    Publication date: October 9, 2008
    Inventors: Jian Ni, Reiner L. Gentz, Guo-Liang Yu, Craig A. Rosen
  • Publication number: 20080220431
    Abstract: The invention provides methods for fusing a first cell with a second cell to form a hybrid cell. The methods involve incubating a first parental cell producing a first partner of a fusogenic binding partner pair on its surface with a second parental cell producing a second partner of the fusogenic binding partner pair on its surface. In certain embodiments, the parental cells are incubated with a known fusogen such as polyethylene glycol and the fusogenic binding partner pair increases the rate of cell fusion. In many embodiments, the first cell is an antibody producing cell, the second cell is an immortal cell, and the hybrid cell is a hybridoma cell that produces a monoclonal antibody. Also provided by the invention are methods for producing hybridoma cells, and methods for screening those cells for production of a monoclonal antibody of interest. The invention further provides systems and kits for carrying out the subject methods.
    Type: Application
    Filed: November 8, 2007
    Publication date: September 11, 2008
    Inventor: Guo-Liang Yu
  • Publication number: 20080212208
    Abstract: The invention discloses a lens set adapted to a webcam. The webcam has a first focal length. The lens set according to the invention includes a first lens and a second lens. The first lens is used to refract a light to generate a refracted light substantially parallel to an optical axis of the first lens. The second lens is used to focus the refracted light and project it to the webcam. The combination of the lens set and the webcam has a second focal length smaller than the first focal length.
    Type: Application
    Filed: February 29, 2008
    Publication date: September 4, 2008
    Applicant: DARFON ELECTRONICS CORP.
    Inventors: Liang Yu YAO, Chun Chung HUANG, Tsai Jung HU, Jung Ying YAO
  • Patent number: 7413763
    Abstract: A method of transferring imprint carbon nano-tube (CNT) field emitting source is disclosed. Firstly, cathode lines are screen printed on a substrate. Then a dielectric layer formation on the cathode lines and substrate is followed. Afterward, gate lines formed on the dielectric layer by screen printing are performed. Next a patterning process is carried out to form openings. Subsequently, an imprint negative mold is dipped with CNT paste and imprinted the CNT paste on the cathode lines through the openings. After drawing of pattern from the imprint mold, the CNT paste is cured by annealing. Since the emitting sources are formed through the imprint negative mold, as a result, the size and shape can be predetermined. Moreover, the intervals between gate line and the emitting source are readily control, which resolve the circuit short problem between gate and cathode. Consequently, the current density, brightness, and uniformity of the emitter sources are significantly improved.
    Type: Grant
    Filed: November 14, 2003
    Date of Patent: August 19, 2008
    Assignee: Industrial Technology Research Institute
    Inventors: Ching-Hsun Chao, Jyh-Rong Sheu, Liang-Yu Chiang, Yu-Yang Chang, Cheng-Chung Lee
  • Publication number: 20080190428
    Abstract: A method for controlling continuous positive airway pressure includes the steps of building up air flow pressure to an initial air flow pressure, increasing the initial air flow pressure to a detection air flow pressure, detecting consistency between the initial air flow pressure and the detection air flow pressure, checking to see if the initial time frame for consistency detection is due, decreasing air flow pressure from the detection air flow pressure to an intermittent air flow pressure and increasing the intermittent air flow pressure to a treatment air flow pressure.
    Type: Application
    Filed: February 12, 2007
    Publication date: August 14, 2008
    Applicant: APEX MEDICAL CORP.
    Inventor: Ching-Liang YU
  • Publication number: 20080187437
    Abstract: An air blower includes a base having a raised column, an arcuate recess between an inner face of the base and an outer periphery of the column and a bottom nozzle, a fan assembly mounted on top of the raised column to generate air flow and having a conical top face, and a cap securely combined with the base and having a top nozzle combined with the bottom nozzle to form an outlet so that the air flow generated by the fan assembly is first directed to the inner face of the cap and then spiraled downward along the raised column to escape the outlet via the arcuate recess.
    Type: Application
    Filed: February 7, 2007
    Publication date: August 7, 2008
    Inventors: Ching-Liang Yu, Yao-Ming Cheng, Kung-Kuan Lai
  • Patent number: 7402409
    Abstract: The invention provides methods for fusing a first cell with a second cell to form a hybrid cell. The methods involve incubating a first parental cell producing a first partner of a fusogenic binding partner pair on its surface with a second parental cell producing a second partner of the fusogenic binding partner pair on its surface. In certain embodiments, the parental cells are incubated with a known fusogen such as polyethylene glycol and the fusogenic binding partner pair increases the rate of cell fusion. In many embodiments, the first cell is an antibody producing cell, the second cell is an immortal cell, and the hybrid cell is a hybridoma cell that produces a monoclonal antibody. Also provided by the invention are methods for producing hybridoma cells, and methods for screening those cells for production of a monoclonal antibody of interest. The invention further provides systems and kits for carrying out the subject methods.
    Type: Grant
    Filed: January 23, 2003
    Date of Patent: July 22, 2008
    Assignee: Epitomics, Inc.
    Inventor: Guo-Liang Yu
  • Publication number: 20080171016
    Abstract: The present invention relates to novel Death Domain Containing Receptor (DR3 and DR3-V1) proteins that are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR3 and DR3-V1 proteins. DR3 and DR3-V1 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Also provided are antibodies and fragments thereof that bind to polypeptides of the invention. The invention further relates to screening methods for identifying agonists and antagonists of DR3 and DR3-V1 activity.
    Type: Application
    Filed: March 11, 2008
    Publication date: July 17, 2008
    Applicant: Human Genome Sciences, Inc.
    Inventors: Guo-Liang Yu, Jian Ni, Reiner L. Gentz, Patrick J. Dillon
  • Publication number: 20080172399
    Abstract: The present invention is directed towards systems and method for organization of bookmarks. The method according to one embodiment comprises retrieving one or more bookmarks associated with one or more content items, a given bookmark generated by a user of a client device and identifying one or more tags associated with one or uniform resource locators corresponding to the or more bookmarks. A bookmark folder hierarchy is created through use of a clustering algorithm on the basis of the one or more tags associated with the one or more uniform resource locators corresponding to the one or more bookmarks.
    Type: Application
    Filed: January 17, 2007
    Publication date: July 17, 2008
    Inventors: Liang-Yu Chi, Dmitry Yurievich Pavlov, Yun Fu, Eren Manavoglu, Paul Heymann, Zhichen Xu