Abstract: The present invention provides a method and system for customized search results in an advanced search results page including vertical searching pivot points for personalizing and refining searching operations. The method includes tracking user network activities and receiving a search query from the user, the search query including a plurality of search terms. The method and system includes identifying a plurality of preferred content sources based on the tracked network activities and retrieving content items in response to the search query. The method and system filters the content items based on the preferred content sources and therein generates a search result page displaying at least a portion of the filtered content items and at least one of the preferred content sources, wherein the display of the at least one preferred content source allows the user to pivot the search results portion based solely on the preferred content source.

Abstract: The present invention provides a method and system for generating search results including receiving a search request and accessing a corpus of data to determine relevant content for inclusion in a search result set on the basis of the search request. The method and system includes determining at least one pivot data point, the at least one pivot data point being contextually related to the search result set on the basis of a review of the search result set and generating an active data link for refinement of the search result set on the basis of the data pivot point. The method and system further includes generating a search result output display for the presentation of at least a portion of the search result set and the active data links and toggling the search result output display to present refinement of the search results set.

Abstract: In certain embodiments, the method may comprise: a) obtaining the antibody sequences from a population of B cells; b) grouping the antibody sequences to provide a plurality of groups of lineage-related antibodies; c) testing a single antibody from each of the groups in a bioassay and, after the first antibody has been identified, d) testing further antibodies that are in the same group as the first antibody in a second bioassay. In another embodiment, the method may comprise: a) testing a plurality of antibodies obtained from a first portion of an antibody producing organ of an animal; b) obtaining the sequence of a first identified antibody; c) obtaining from a second portion of said antibody producing organ the sequences of further antibodies that are related by lineage to said first antibody; and, c) testing the further antibodies in a second bioassay.

Abstract: The present invention relates to a Neutrokine-alpha antibody and a process for producing a Neutrokine-alpha antibody. The invention further relates to screening methods for identifying compounds that inhibit or enhance the action of Neutrokine-alpha. Also provided are diagnostic methods for detecting autoimmune disorders and therapeutic methods for treating autoimmune disorders using a Neutrokine-alpha antibody.

Abstract: A vehicle collision avoidance system is implemented in a host vehicle. A wireless communication module in the host vehicles wirelessly broadcasts vehicle information packages of the host vehicle and receives external vehicle information packages from other neighboring vehicles. Based on the received vehicle information packages, a collision avoidance process is performed. The process has steps of mapping coordinates system, categorizing collision zones, determining whether a possible collision position exists, calculating a collision time and outputting warning messages. The estimations of the possible collision position and the collision time are not affected by the positions of the neighboring vehicles. Therefore, the neighboring vehicles approaching the host vehicle from different direction are effectively monitored.

Abstract: A compression device for medical treatment includes an upper colloid sheet, a lower colloid sheet, and a plurality of gas ports. The upper colloid sheet is stacked with the lower colloid sheet and welded, so as to form a plurality of isolated cells with welded walls, and each cell respectively corresponds to one of the gas ports. Therein, the welded walls that neighbors each cell extend diagonally along an angle that is between an x-axis direction and an y-axis direction, so that the welded walls extends from an edge of the upper colloid sheet and the lower colloid sheet to another edge of the upper colloid sheet and the lower colloid sheet. Per aforementioned, the compression device for medical treatment has diagonally formed cells, which results in compression from two directions, so that the medical benefits are increased.

Abstract: An antibody is provided. In certain cases, the antibody comprises: a) a heavy chain variable domain that comprises CDR regions that are substantially identical to the heavy chain CDR regions of a selected antibody and b) a light chain variable domain that comprises CDR regions that are substantially identical to the light chain CDR regions of the selected antibody, where the antibody binds a selected target.

Abstract: A foldable handheld device is disclosed, which includes a first casing, a second casing, a connecting mechanism for connecting the first casing to the second casing, and an elastic piece disposed on the first casing. The second casing has a support surface and a curved surface connecting to the support surface, wherein the curved surface has a concave portion. An end of the elastic piece has a protrusion disposed thereon, wherein the protrusion is kept touching the second casing when the second casing is rotated related to the first casing along a rotating axle.

Abstract: Human TNF-gamma-alpha and TNF-gamma-beta polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing such polypeptides to inhibit cellular growth, for example in a tumor or cancer, for facilitating wound-healing, to provide resistance against infection, induce inflammatory activities, and stimulating the growth of certain cell types to treat diseases, for example restenosis. Also disclosed are diagnostic methods for detecting a mutation in the TNF-gamma-alpha and TNF-gamma-beta nucleic acid sequences or overexpression of the TNF-gamma-alpha and/or TNF-gamma-beta polypeptides. Antagonists against such polypeptides and their use as a therapeutic to treat cachexia, septic shock, cerebral malaria, inflammation, arthritis and graft-rejection are also disclosed.

Abstract: The present invention relates to a novel Neutrokine-alpha, and a splice variant thereof designated Neutrokine-alphaSV, polynucleotides and polypeptides which are members of the TNF family. In particular, isolated nucleic acid molecules are provided encoding the human Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides, including soluble forms of the extracellular domain. Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of Neutrokine-alpha and/or Neutrokine-alphaSV activity. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders.

Abstract: A method for producing a library of engineered-antibody producing cells is provided. In certain cases, the method includes isolating nucleic acid sequences encoding IgH variable regions and IgL variable regions from a plurality of antibody producing cells, and introducing the nucleic acids into host cells to obtain cells that produce antibodies comprising non-naturally paired IgH and IgL variable chains.

Abstract: The present invention relates to a blood flow simulation system, which comprises a first container, a phantom, and a second container. The blood flow simulation system according to the present invention contains a fluid by the first container. Then the phantom is used for transporting the fluid. Afterwards, the second container is used for containing the fluid output by the phantom, and transporting the fluid to the first container by way of the phantom. Thereby, the blood-vessel characteristics, the blood-flow characteristics, and the human muscle characteristics can be simulated effectively and hence facilitating experimental convenience.

Abstract: A keyboard connecting mechanism includes a frame, a cable, and a socket. The frame is connected to a keyboard. At least one first positioning structure is disposed on the frame. The cable is disposed on a side of the frame. The cable includes a plurality of pins, and at least one hole is formed on the cable. The socket includes a base. At least one second positioning structure is formed on a first side of the base for connecting with the first positioning structure so as to fix the frame and the cable. The socket further includes a plurality of fragments disposed on the first side of the base for applying elastic force to the plurality of pins of the cable. The socket further includes at least one elastic structure disposed on a lateral side of the base for fixing the frame elastically.

Abstract: A dual-mode electrical plug includes an insulating body formed with a channel and an elongate guiding aperture; a pair of conductive components disposed on the insulating body; a ground prong including a hollow prong body disposed in the channel and movable between an extended position and a retracted position, and the prong body defining a wire containing space, the ground prong further including an operating part disposed on an outer surface of the prong body, the operating part extending through and being movable in the elongate guiding aperture so as to drive movement of the prong body; and a ground wire extending into the wire containing space and including a connecting end for connecting electrically to an inner surface of the prong body.

Abstract: Human TNF-gamma-alpha and TNF-gamma-beta polypeptides and DNA (RNA) encoding such polypeptides and a procedure for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing such polypeptides to inhibit cellular growth, for example in a tumor or cancer, for facilitating wound-healing, to provide resistance against infection, induce inflammatory activities, and stimulating the growth of certain cell types to treat diseases, for example restenosis. Also disclosed are diagnostic methods for detecting a mutation in the TNF-gamma-alpha and TNF-gamma-beta nucleic acid sequences or overexpression of the TNF-gamma-alpha and/or TNF-gamma-beta polypeptides. Antagonists against such polypeptides and their use as a therapeutic to treat cachexia, septic shock, cerebral malaria, inflammation, arthritis and graft-rejection are also disclosed.

Abstract: An opening mechanism includes a base whereon an opening is disposed, and a covering including a main body for covering the opening. The covering further includes a hook connected to the main body for hooking the base. The covering further includes a buckling part connected to a side of the main body. The opening mechanism further includes a sliding component passing through the buckling part. An end of the sliding component is disposed on a breach of the main body. An engaging part is formed on a side of the sliding component for engaging with a fixing end. The opening mechanism further includes an elastic component installed on the side of the main body and disposed on a side of the sliding component for providing elastic force to the sliding component so as to drive the engaging part of the sliding component to engage with the fixing end.

Abstract: The present invention relates to novel Death Domain Containing Receptor (DR3 and DR3-V1) proteins that are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR3 and DR3-V1 proteins. DR3 and DR3-V1 polypeptides are also provided, as are vectors, host cells and recombinant methods for producing the same. Also provided are antibodies and fragments thereof that bind to polypeptides of the invention. The invention further relates to screening methods for identifying agonists and antagonists of DR3 and DR3-V1 activity.

Abstract: A cavity free, broadband approach for engineering photon emitter interactions via sub-wavelength confinement of optical fields near metallic nanostructures. When a single CdSe quantum dot (QD) is optically excited in close proximity to a silver nanowire (NW), emission from the QD couples directly to guided surface plasmons in the NW, causing the wire's ends to light up. Nonclassical photon correlations between the emission from the QD and the ends of the NW demonstrate that the latter stems from the generation of single, quantized plasmons. Results from a large number of devices show that the efficient coupling is accompanied by more than 2.5-fold enhancement of the QD spontaneous emission, in a good agreement with theoretical predictions.

Abstract: The present invention relates to nucleic acid molecules encoding Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides, including soluble forms of the extracellular domain Neutrokine-alpha and/or Neutrokine-alphaSV polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to antibodies or portions thereof that specifically bind Neutrokine-alpha and/or Neutrokine-alphaSV and diagnostic and therapeutic methods using these antibodies. Also provided are diagnostic methods for detecting immune system-related disorders and therapeutic methods for treating immune system-related disorders using the compositions of the invention.

Abstract: The present invention relates to a Neutrokine-alpha antibody and a process for producing a Neutrokine-alpha antibody. The invention further relates to screening methods for identifying compounds that inhibit or enhance the action of Neutrokine-alpha. Also provided are diagnostic methods for detecting autoimmune disorders and therapeutic methods for treating autoimmune disorders using a Neutrokine-alpha antibody.