Patents by Inventor Lihong Sun

Lihong Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170174710
    Abstract: Compounds of formula (I) can modulate the activity of one or more S1P receptors and/or the activity of autotaxin (ATX).
    Type: Application
    Filed: December 2, 2016
    Publication date: June 22, 2017
    Inventors: Kevin M. Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Hairuo Peng, Zhaohui Shao, Lihong Sun, Arthur G. Taveras, Zhili Xin, Lei Zhang
  • Publication number: 20170158687
    Abstract: Disclosed are bicyclic aryl compounds of formula (I), that can modulate the activity of the autotaxin (ATX) enzyme. This invention further relates to compounds that are ATX inhibitors, and methods of making and using such compounds in the treatment of demyelination due to injury or disease, as well as for treating proliferative disorders such as cancer.
    Type: Application
    Filed: October 18, 2016
    Publication date: June 8, 2017
    Inventors: Kevin M. Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Hairuo Peng, Zhaohui Shao, Lihong Sun, Arthur G. Taveras, Deping Wang, Zhili Xin, Lei Zhang
  • Patent number: 9555050
    Abstract: Compounds of formula (I) can modulate the activity of autotaxin (ATX).
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: January 31, 2017
    Assignee: BIOGEN MA INC.
    Inventors: Kevin Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Zhaohui Shao, Lihong Sun, Arthur Taveras, Deping Wang, Zhili Xin, Lei Zhang
  • Patent number: 9550798
    Abstract: Compounds of formula (I) can modulate the activity of one or more SIP receptors and/or the activity of autotaxin (ATX).
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: January 24, 2017
    Assignee: BIOGEN MA INC.
    Inventors: Kevin Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Hairuo Peng, Zhaohui Shao, Lihong Sun, Arthur Taveras, Zhili Xin, Lei Zhang
  • Patent number: 9546165
    Abstract: The present invention provides compounds useful as inhibitors of PDK1. The present invention also provides compositions thereof, and methods of treating PDK1-mediated diseases.
    Type: Grant
    Filed: October 5, 2010
    Date of Patent: January 17, 2017
    Assignees: Sunesis Pharmaceuticals, Inc., Millennium Pharmaceuticals, Inc.
    Inventors: Joseph Arndt, Timothy Chan, Kevin Guckian, Gnanasambandam Kumaravel, Wen-Cherng Lee, Edward Yin-Shiang Lin, Daniel Scott, Lihong Sun, Jermaine Thomas, Kurt van Vloten, Deping Wang, Lei Zhang, Daniel Erlanson
  • Patent number: 9522889
    Abstract: Disclosed are bicyclic aryl compounds of formula (I), that can modulate the activity of the autotaxin (ATX) enzyme. This invention further relates to compounds that are ATX inhibitors, and methods of making and using such compounds in the treatment of demyelination due to injury or disease, as well as for treating proliferative disorders such as cancer.
    Type: Grant
    Filed: July 26, 2013
    Date of Patent: December 20, 2016
    Assignee: BIOGEN MA INC.
    Inventors: Kevin Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Hairuo Peng, Zhaohui Shao, Lihong Sun, Arthur Taveras, Deping Wang, Zhili Xin, Lei Zhang
  • Patent number: 9499485
    Abstract: Compounds of formula (I) can modulate the activity of one or more SIP receptors and/or the activity of autotaxin (ATX).
    Type: Grant
    Filed: August 5, 2013
    Date of Patent: November 22, 2016
    Assignee: BIOGEN MA INC.
    Inventors: Kevin Guckian, Gnanasambandam Kumaravel, Bin Ma, Lihong Sun, Zhili Xin, Lei Zhang
  • Publication number: 20160331756
    Abstract: The present invention provides compounds useful as inhibitors of PDK1. The present invention also provides compositions thereof, and methods of treating PDK1-mediated diseases.
    Type: Application
    Filed: December 11, 2015
    Publication date: November 17, 2016
    Inventors: Joseph Arndt, Timothy Chan, Kevin Guckian, Gnanasambandam Kumaravel, Wen-Cherng Lee, Edward Yin-Shiang Lin, Daniel Scott, Lihong Sun, Jermaine Thomas, Kurt van Vloten, Deping Wang, Lei Zhang, Daniel Erlanson
  • Publication number: 20160311802
    Abstract: The present invention provides compounds and compositions thereof which are useful as inhibitors of Bruton's tyrosine kinase and which exhibit desirable characteristics for the same.
    Type: Application
    Filed: December 11, 2014
    Publication date: October 27, 2016
    Inventors: Brian T. Hopkins, Bin Ma, Timothy Raymond Chan, Lihong Sun, Lei Zhang, Gnanasambandam Kumaravel, Joseph P. Lyssikatos, Kevin Koch, Hua Miao
  • Patent number: 9455794
    Abstract: A master device transmits beacon messages to a plurality of slave devices. The beacon messages specify upstream time slots, downstream time slots, and contention-based time slots. To register a respective slave device with the master device, the respective slave device transmits an association request to the master device during a contention-based time slot and receives an association response from the master device during a first downstream time slot. In response to receiving the association response, the respective slave device transmits an authentication request to the master device during an upstream time slot and receives an authentication response from the master device during a second downstream time slot.
    Type: Grant
    Filed: October 29, 2012
    Date of Patent: September 27, 2016
    Assignee: QUALCOMM Incorporated
    Inventors: Haipeng Wu, Patrick Tse, Xin Liang, Lihong Sun
  • Publication number: 20160039825
    Abstract: Compounds of formula (I), and pharmaceutically acceptable salts thereof, can modulate the activity of one or more SIP receptors and/or the activity of autotaxin (ATX).
    Type: Application
    Filed: March 14, 2014
    Publication date: February 11, 2016
    Inventors: Hairuo Peng, Zhili Xin, Lei Zhang, Lihong Sun, Gnanasambandam Kumaravel, Art Taveras, Deping Wang
  • Publication number: 20150299123
    Abstract: Compounds of formula (I), and pharmaceutically acceptable salts thereof, can modulate the activity of one or more SIP receptors and/or the activity of autotaxin (ATX).
    Type: Application
    Filed: November 20, 2013
    Publication date: October 22, 2015
    Inventors: Hairuo Peng, Zhili Xin, Lihong Sun, Timothy Chan, Gnanasambandam Kumaravel, Arthur G. Taveras
  • Publication number: 20150249515
    Abstract: A master device transmits beacon messages to a plurality of slave devices. The beacon messages specify upstream time slots, downstream time slots, and contention-based time slots. To register a respective slave device with the master device, the respective slave device transmits an association request to the master device during a contention-based time slot and receives an association response from the master device during a first downstream time slot. In response to receiving the association response, the respective slave device transmits an authentication request to the master device during an upstream time slot and receives an authentication response from the master device during a second downstream time slot.
    Type: Application
    Filed: October 29, 2012
    Publication date: September 3, 2015
    Inventors: Haipeng Wu, Patrick Tse, Xin Liang, Lihong Sun
  • Publication number: 20150246063
    Abstract: Compounds of formula (I) can modulate the activity of autotaxin (ATX).
    Type: Application
    Filed: July 26, 2013
    Publication date: September 3, 2015
    Applicant: BIOGEN IDEC MA INC.
    Inventors: Kevin Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Zhaohui Shao, Lihong Sun, Arthur Taveras, Deping Wang, Zhili Xin, Lei Zhang
  • Publication number: 20150210647
    Abstract: Disclosed are bicyclic aryl compounds of formula (I), that can modulate the activity of the autotaxin (ATX) enzyme. This invention further relates to compounds that are ATX inhibitors, and methods of making and using such compounds in the treatment of demyelination due to injury or disease, as well as for treating proliferative disorders such as cancer.
    Type: Application
    Filed: July 26, 2013
    Publication date: July 30, 2015
    Inventors: Kevin Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Hairuo Peng, Zhaohui Shao, Lihong Sun, Arthur Taveras, Deping Wang, Zhili Xin, Lei Zhang
  • Publication number: 20150203493
    Abstract: Compounds of formula (I) can modulate the activity of one or more SIP receptors and/or the activity of autotaxin (ATX).
    Type: Application
    Filed: August 5, 2013
    Publication date: July 23, 2015
    Applicant: BIOGEN IDEC MA INC.
    Inventors: Kevin Guckian, Gnanasambandam Kumaravel, Bin Ma, Lihong Sun, Zhili Xin, Lei Zhang
  • Publication number: 20150203515
    Abstract: Compounds of formula (I) can modulate the activity of one or more SIP receptors and/or the activity of autotaxin (ATX).
    Type: Application
    Filed: July 26, 2013
    Publication date: July 23, 2015
    Inventors: Kevin Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Hairuo Peng, Zhaohui Shao, Lihong Sun, Arthur Taveras, Zhili Xin, Lei Zhang
  • Publication number: 20150183741
    Abstract: Compounds of formula (I) can modulate the activity of one or more SIP receptors and/or the activity of autotaxin (ATX).
    Type: Application
    Filed: August 5, 2013
    Publication date: July 2, 2015
    Inventors: Kevin Guckian, Gnanasambandam Kumaravel, Bin Ma, Lihong Sun, Zhili Xin, Lei Zhang
  • Publication number: 20150018351
    Abstract: The present invention provides pyridinonyl PDK1 inhibitors and methods of treating cancer using the same.
    Type: Application
    Filed: July 10, 2014
    Publication date: January 15, 2015
    Inventors: Kenneth Egnard Lind, Kathy Cao, Edward Yin-shiang Lin, Thinh Ba Nguyen, Bradley T. Tangonan, Daniel A. Erlanson, Kevin Guckian, Robert Lowell Simmons, Wen-cherng Lee, Lihong Sun, Stig Hansen, Nuzhat Pathan, Lei Zhang
  • Patent number: 8778977
    Abstract: The present invention provides pyridinonyl PDK1 inhibitors and methods of treating cancer using the same.
    Type: Grant
    Filed: July 2, 2007
    Date of Patent: July 15, 2014
    Assignee: Sunesis Pharmaceuticals, Inc.
    Inventors: Kenneth Egnard Lind, Kathy Cao, Edward Yin-shiang Lin, Thinh Ba Nguyen, Bradley T. Tangonan, Daniel A. Erlanson, Kevin Guckian, Robert Lowell Simmons, Wen-cherng Lee, Lihong Sun, Stig Hansen, Nuzhat Pathan, Lei Zhang