Patents by Inventor Lijun Sun

Lijun Sun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SEAWEED MEAL AND METHOD OF MAKING THE SAME
    Publication number: 20200329749
    Abstract: Provided are methods of making high quality seaweed meal suitable for food applications. The method comprises the steps of cleaning the fresh, dried, or rehydrated red seaweed, pretreating the red seaweed with a salt under heat, and drying and grinding the treated red seaweed to obtain the seaweed meal. Optionally, the method comprises bleaching the red seaweed, and/or hydrolyzing the red seaweed with cellulase. The seaweed meal produced by the disclosed technology has a light color, good flavor and taste, good mouthfeel, high gelling capability, great stability, and ideal smoothness and slipperiness suitable for food applications.
    Type: Application
    Filed: July 6, 2020
    Publication date: October 22, 2020
    Inventor: Lijun SUN
  • PHARMACEUTICAL TARGETING OF A MAMMALIAN CYCLIC DI-NUCLEOTIDE SIGNALING PATHWAY
    Publication number: 20200308216
    Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2?3-cGAMP, 2?2-cGAMP, 3?2?-cGAMP and 3?3?-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.
    Type: Application
    Filed: June 16, 2020
    Publication date: October 1, 2020
    Applicant: The Board of Regents of the University of Texas System
    Inventors: Zhijian CHEN, Lijun SUN, Jiaxi WU, Heping SHI, Chuo CHEN
  • Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
    Patent number: 10696710
    Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2?3-cGAMP, 2?2-cGAMP, 3?2?-cGAMP and 3?3?-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.
    Type: Grant
    Filed: December 13, 2019
    Date of Patent: June 30, 2020
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Zhijian Chen, Lijun Sun, Jiaxi Wu, Heping Shi, Chuo Chen
  • COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES
    Publication number: 20200199078
    Abstract: The present disclosure provides compounds of Formula (I). The compounds described herein may be useful in treating and/or preventing proliferative diseases (e.g., cancer). Also provided in the present disclosure are pharmaceutical compositions, kits, methods, and uses including or using a compound described herein.
    Type: Application
    Filed: November 30, 2016
    Publication date: June 25, 2020
    Applicants: Children's Medical Center Corporation, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Bruce R. Zetter, Lijun Sun
  • SUPERABSORBENT MATERIALS AND METHODS OF MAKING THE SAME
    Publication number: 20200197904
    Abstract: Provided are superabsorbent materials composed of agar, and one or more water-soluble natural polysaccharides, and dietary compositions containing such superabsorbent materials. The disclosed superabsorbent materials have various food and therapeutic applications and can be used as loading vehicles for nutrients and therapeutic agents. Also provided are methods for preparing such superabsorbent materials.
    Type: Application
    Filed: March 2, 2020
    Publication date: June 25, 2020
    Inventor: Lijun SUN
  • MAST-CELL MODULATORS AND USES THEREOF
    Publication number: 20200148638
    Abstract: Provided are novel compounds of Formula I: pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders associated with mast cells. Also provided are pharmaceutical compositions comprising the novel compounds of Formula I and methods for their use in treating one or more diseases and disorders associated with mast cells.
    Type: Application
    Filed: January 9, 2020
    Publication date: May 14, 2020
    Inventors: Lijun Sun, Aristidis Veves
  • PHARMACEUTICAL TARGETING OF A MAMMALIAN CYCLIC DI-NUCLEOTIDE SIGNALING PATHWAY
    Publication number: 20200140477
    Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2?3-cGAMP, 2?2-cGAMP, 3?2?-cGAMP and 3?3?-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.
    Type: Application
    Filed: December 13, 2019
    Publication date: May 7, 2020
    Applicant: Board of Regents, The University of Texas System
    Inventors: Zhijian CHEN, Lijun SUN, Jiaxi WU, Heping SHI, Chuo CHEN
  • Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
    Patent number: 10633411
    Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2?3-cGAMP, 2?2-cGAMP, 3?2?-cGAMP and 3?3?-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: April 28, 2020
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Zhijian Chen, Lijun Sun, Jiaxi Wu, Heping Shi, Chuo Chen
  • PHARMACEUTICAL TARGETING OF A MAMMALIAN CYCLIC DI-NUCLEOTIDE SIGNALING PATHWAY
    Publication number: 20200102342
    Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2?3-cGAMP, 2?2-cGAMP, 3?2?-cGAMP and 3?3?-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.
    Type: Application
    Filed: November 18, 2019
    Publication date: April 2, 2020
    Applicant: Board of Regents, The University of Texas System
    Inventors: Zhijian CHEN, Lijun SUN, Jiaxi WU, Heping SHI, Chuo CHEN
  • Enhanced ATRA-related compounds for the treatment of proliferative diseases, autoimmune diseases, and addiction conditions
    Patent number: 10548864
    Abstract: The invention features all-trans retinoic acid (ATRA)-related compounds capable of associating with Pin1 and methods of treating a proliferative disorder characterized by elevated Pin1 marker levels, Pin1 degradation, and/or reduced Pin1 Ser71 phosphorylation in a subject by administering an ATRA-related compound. The invention also features methods of treating proliferative disorders, autoimmune diseases, and addiction conditions (e.g., diseases, disorders, and conditions characterized by elevated Pin1 marker levels) by administering an ATRA-related compound in combination with another therapeutic compound.
    Type: Grant
    Filed: March 10, 2016
    Date of Patent: February 4, 2020
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Kun Ping Lu, Xiao Zhen Zhou, Shuo Wei, Lijun Sun, Michelle Lynn Hall
  • CYCLIC DI-NUCLEOTIDE COMPOUNDS AND METHODS OF USE
    Publication number: 20200010501
    Abstract: Disclosed are cyclic-di-nucleotide cGAMP analogs, methods of synthesizing the compounds, pharmaceutical compositions comprising the compounds thereof, and use of compounds and compositions in medical therapy.
    Type: Application
    Filed: June 11, 2019
    Publication date: January 9, 2020
    Applicants: ImmuneSensor Therapeutics, Inc., The Board of Regents of the University of Texas System
    Inventors: Boyu ZHONG, Heping SHI, Yuanwei DAI, Qi WEI, Chuo CHEN, Zhijian CHEN, Lijun SUN
  • Cyclic di-nucleotide compounds and methods of use
    Patent number: 10519188
    Abstract: Disclosed are cyclic-di-nucleotide cGAMP analogs, methods of synthesizing the compounds, pharmaceutical compositions comprising the compounds thereof, and use of compounds and compositions in medical therapy.
    Type: Grant
    Filed: April 15, 2018
    Date of Patent: December 31, 2019
    Assignees: ImmuneSensor Therapeutics, Inc., The Board of Regents of the University of Texas System
    Inventors: Boyu Zhong, Lijun Sun, Heping Shi, Qi Wei, Yuanwei Dai, Chuo Chen, Zhijian Chen
  • Chalcone compounds
    Patent number: 10512631
    Abstract: This disclosure relates to the compounds of formula (I): [INSERT FORMULA], in which A and R1-R12 are defined in the Specification. The compounds of formula (I) have therapeutic effects, such as treating cancers.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: December 24, 2019
    Assignee: Beth Israel Deaconess Medical Center, Inc.
    Inventors: Barbara Wegiel, Lijun Sun
  • Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
    Patent number: 10508129
    Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2?3-cGAMP, 2?2-cGAMP, 3?2?-cGAMP and 3?3?-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: December 17, 2019
    Assignee: THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
    Inventors: Zhijian Chen, Lijun Sun, Jiaxi Wu, Heping Shi, Chuo Chen
  • SEAWEED MEAL AND METHOD OF MAKING THE SAME
    Publication number: 20190343158
    Abstract: Provided are methods of making high quality seaweed meal suitable for food applications. The method comprises the steps of cleaning the fresh, dried, or rehydrated red seaweed, pretreating the red seaweed with a salt under heat, and drying and grinding the treated red seaweed to obtain the seaweed meal. Optionally, the method comprises bleaching the red seaweed, and/or hydrolyzing the red seaweed with cellulase. The seaweed meal produced by the disclosed technology has a light color, good flavor and taste, good mouthfeel, high gelling capability, great stability, and ideal smoothness and slipperiness suitable for food applications.
    Type: Application
    Filed: June 15, 2018
    Publication date: November 14, 2019
    Inventor: Lijun SUN
  • A SYSTEM FOR DETECTING CRACK GROWTH OF ASPHALT PAVEMENT BASED ON BINOCULAR IMAGE ANALYSIS
    Publication number: 20190339209
    Abstract: A binocular image analysis-based asphalt road surface damage detection system, comprising five sub-systems for crack development degree detection model establishment, information collection, information analysis, information transmission and information distribution. Specifically, road surface damage information detection is performed by means of a mobile platform, a processing end, a temperature measurement-type infrared thermal imaging instrument, an ordinary image collector, a vibration sensor, image processing technology, edge cloud computing technology, an embedded system, system integration technology and real-time positioning technology.
    Type: Application
    Filed: December 30, 2017
    Publication date: November 7, 2019
    Inventors: Yuchuan DU, Xiaoming Zhang, Shengchuan Jiang, Yue Qiu, Guangzhao Chang, Lijun Sun
  • Seaweed meal and method of making the same
    Patent number: 10426184
    Abstract: Provided are methods of making high quality seaweed meal suitable for food applications. The method comprises the steps of cleaning the fresh, dried, or rehydrated red seaweed, pretreating the red seaweed with alkali, pre-treating the red seaweed with acid, hydrolyzing the red seaweed with cellulase, and drying and grinding the treated red seaweed to obtain the seaweed meal. The seaweed meal produced by the disclosed technology has light color, good flavor and taste, good mouthfeel, high gelling capability, great stability, and ideal smoothness and slipperiness suitable for food applications.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: October 1, 2019
    Assignee: NUTRIOMIX, INC.
    Inventor: Lijun Sun
  • PHARMACEUTICAL TARGETING OF A MAMMALIAN CYCLIC DI-NUCLEOTIDE SIGNALING PATHWAY
    Publication number: 20190263851
    Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2?3-cGAMP, 2?2-cGAMP, 3?2?-cGAMP and 3?3?-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies, and diagnostics.
    Type: Application
    Filed: May 7, 2019
    Publication date: August 29, 2019
    Applicant: Board of Regents, The University of Texas System
    Inventors: Zhijian CHEN, Lijun SUN, Jiaxi WU, Heping SHI, Chuo CHEN
  • Pharmaceutical targeting of a mammalian cyclic di-nucleotide signaling pathway
    Patent number: 10336786
    Abstract: Cyclic-GMP-AMP synthase (cGAS) and cyclic-GMP-AMP (cGAMP), including 2?3-cGAMP, 2?2-cGAMP, 3?2?-cGAMP and 3?3?-GAMP, are used in pharmaceutical formulations (including vaccine adjuvants), drug screens, therapies and diagnostics.
    Type: Grant
    Filed: December 16, 2013
    Date of Patent: July 2, 2019
    Assignee: Board of Regents, The University of Texas System
    Inventors: Zhijian Chen, Lijun Sun, Jiaxi Wu, Heping Shi, Chuo Chen
  • MAST-CELL MODULATORS AND USES THEREOF
    Publication number: 20190016680
    Abstract: Provided are novel compounds of Formula I pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders associated with mast cells. Also provided are pharmaceutical compositions comprising the novel compounds of Formula I and methods for their use in treating one or more diseases and disorders associated with mast cells.
    Type: Application
    Filed: January 13, 2017
    Publication date: January 17, 2019
    Inventors: Lijun Sun, Aristidis Veves