Patents by Inventor Lily Lu

Lily Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Water-soluble rhodamine dye conjugates
    Patent number: 7504496
    Abstract: The present invention provides novel, water-soluble, red-emitting fluorescent rhodamine dyes and red-emitting fluorescent energy-transfer dye pairs, as well as labeled conjugates comprising the same and methods for their use. The dyes, energy-transfer dye pairs and labeled conjugates are useful in a variety of aqueous-based applications, particularly in assays involving staining of cells, protein binding, and/or analysis of nucleic acids, such as hybridization assays and nucleic acid sequencing.
    Type: Grant
    Filed: February 14, 2005
    Date of Patent: March 17, 2009
    Inventors: Linda G. Lee, Ronald J. Graham, William E. Werner, Elana Swartzman, Lily Lu
  • Isoforms of eIF-5A: senescence-induced eLF5A; wounding-induced eIF-4A; growth eIF-5A; and DHS
    Patent number: 7358418
    Abstract: The present invention relates to unique isoforms of eukaryotic initiation Factor 5A (“eIF-5A”): senescence-induced eIF-5A; wounding-induced eIF-5A; and growth eIF-5A, as well as polynucleotides that encode these three factors. The present invention also relates to methods involving modulating the expression of these factors. The present invention also relates to deoxyhypusine synthase (“DHS”), polynucleotides that encode DHS, and methods involving modulating the expression of DHS.
    Type: Grant
    Filed: June 8, 2004
    Date of Patent: April 15, 2008
    Assignee: Senesco Technologies, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • Polynucleotides encoding carnation senescence-induced DHS
    Patent number: 7265280
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced elF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced elF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: September 4, 2007
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • Isolated nucleotides encoding arabidopsis senescence-induced elF-5A
    Patent number: 7226784
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced eIF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: June 5, 2007
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants
    Patent number: 7217866
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced eIF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: May 15, 2007
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • Splice variant of the vanilloid receptor VR1A
    Publication number: 20060292639
    Abstract: The invention provides a splice variant of the vanilloid receptor termed “VR1A.” VR1A has a unique N-terminus as compared with wild type VR1. The invention provides nucleic acid sequences encoding VR1A, expression vectors for expressing VR1A, amino acid sequences of VR1A, antibodies against VR1A and methods of making and using the polynucleotides, polypeptides and antibodies of the invention.
    Type: Application
    Filed: August 11, 2005
    Publication date: December 28, 2006
    Applicant: Adolor Corporation
    Inventors: Per-Erik Mansson, Diane DeHaven-Hudkins, Lily Lu
  • Isolated nucleotides encoding tomato senescence-induced eIF-5A
    Patent number: 7070997
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced eIF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: July 4, 2006
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • Polynucleotides encoding carnation senescense-induced EIF-5A
    Patent number: 7033833
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced eIF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: April 25, 2006
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • DNA encoding a plant deoxyhpusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants
    Patent number: 6989258
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced elF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced elF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: January 24, 2006
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • Water-soluble rhodamine dye conjugates
    Publication number: 20050153355
    Abstract: The present invention provides novel, water-soluble, red-emitting fluorescent rhodamine dyes and red-emitting fluorescent energy-transfer dye pairs, as well as labeled conjugates comprising the same and methods for their use. The dyes, energy-transfer dye pairs and labeled conjugates are useful in a variety of aqueous-based applications, particularly in assays involving staining of cells, protein binding, and/or analysis of nucleic acids, such as hybridization assays and nucleic acid sequencing.
    Type: Application
    Filed: February 14, 2005
    Publication date: July 14, 2005
    Applicant: Applera Corporation
    Inventors: Linda Lee, Ronald Graham, William Werner, Elana Swartzman, Lily Lu
  • Tomato antisense deoxyhypusine synthase molecule and method of inhibiting deoxyhypusine synthase expression in plants
    Patent number: 6900368
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced elF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced elF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: May 31, 2005
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • Carnation antisense deoxyhypusine synthase molecule and method of inhibiting deoxyhypusine synthase expression in plants
    Patent number: 6897359
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced elF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced elF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: May 24, 2005
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants
    Patent number: 6878860
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced elF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced elF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: November 29, 2000
    Date of Patent: April 12, 2005
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • Separation of olefinic isomers
    Patent number: 6861512
    Abstract: The geometric isomers of olefins and olefinic compounds are separated by means of liquid chromatography using a stationary phase comprising an organosilane with a pendant aliphatic functional group such as C18 and a mobile phase which includes an additive comprising alkanes and alkenes.
    Type: Grant
    Filed: March 1, 2001
    Date of Patent: March 1, 2005
    Assignee: Eisai Co., Ltd.
    Inventors: Lily Lu, John D. Orr
  • DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants
    Patent number: 6855529
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced elF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced elF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: February 15, 2005
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • Arabidopsis antisense deoxyhypusine synthase molecule and method of inhibiting deoxyhypusine synthase expression in plants
    Patent number: 6849782
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced eIF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Grant
    Filed: January 13, 2003
    Date of Patent: February 1, 2005
    Assignee: Senesco, Inc.
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants
    Publication number: 20030182688
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced eIF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Application
    Filed: January 13, 2003
    Publication date: September 25, 2003
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants
    Publication number: 20030140377
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced eIF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Application
    Filed: January 13, 2003
    Publication date: July 24, 2003
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants
    Publication number: 20030115635
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced eIF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Application
    Filed: January 13, 2003
    Publication date: June 19, 2003
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu
  • DNA encoding a plant deoxyhypusine synthase, a plant eukaryotic initiation factor 5A, transgenic plants and a method for controlling senescence programmed and cell death in plants
    Publication number: 20030115636
    Abstract: Regulation of expression of programmed cell death, including senescence, in plants is achieved by integration of a gene or, gene fragment encoding senescence-induced deoxyhypusine synthase, senescence-induced eIF-5A or both into the plant genome in antisense orientation. Plant genes encoding senescence-induced deoxyhypusine synthase and senescence-induced eIF-5A are identified and the nucleotide sequences of each, alone and in combination are used to modify senescence in transgenic plants.
    Type: Application
    Filed: January 13, 2003
    Publication date: June 19, 2003
    Inventors: John E. Thompson, Tzann-Wei Wang, Dongen Lily Lu