Abstract: T-cell receptors that recognize MART-1 antigen are provided. The TCRs can be used, for example, to treat patients suffering from melanoma.

Abstract: Methods and compositions are provided for delivering a polynucleotide encoding a gene of interest to a target cell using a virus. The virus envelope comprises a cell-specific binding determinant that recognizes and binds to a component on the target cell surface, leading to endocytosis of the virus. A separate fusogenic molecule is also present on the envelope and facilitates delivery of the polynucleotide across the membrane and into the cytosol of the target cell. The methods and related compositions can be used for treating patients having suffering from a wide range of conditions, including infection, such as HIV; cancers, such as non-Hodgkin's lymphoma and breast cancer; and hematological disorders, such as severe combined immunodeficiency.

Abstract: The invention provides systems and methods for the generation of lymphocytes having a unique antigen specificity. In a preferred embodiment, the invention provides methods of virally infecting cells from bone marrow with one or more viral vectors that encode antigen-specific antibodies for the production of, for example B cells and T cells. In some embodiments, the viral vectors include an IRES or 2A element to promote separation of, for example, the ? subunit and ? subunit of a T cell receptor (TCR) or heavy and light chains of a B-cell antibody. The resulting lymphocytes, express the particular antibody that was introduced in the case of B cells and TCR in the case of T cells. The lymphocytes generated can be used for a variety of therapeutic purposes including the treatment of various cancers and the generation of a desired immune response to viruses and other pathogens. The resulting cells develop normally and respond to antigen both in vitro and in vivo.

Abstract: A method for operating a communication station in a communicating environment includes: (a) monitoring the environment to ascertain whether the station is receiving an unintended sensed signal not intended for the station from at least one signal source; (b) if the station has not received a predetermined number of unintended sensed signals during a predetermined time interval, operating the station in an omni-directional mode; and (c) if the station has received a predetermined number of sensed signals during the predetermined time interval, saving an indication of a reception direction from which arrived each unintended sensed signal; and operating the station in a directional mode. While in the directional mode, the station is sensitive to receiving signals arriving from a sensing direction other than from a reception direction, and the station transmits signals toward the sensing direction.

Abstract: Techniques for ordered and duplicate-free delivery of wireless data frames are provided. A source address, a destination address, and a message sequence number are acquired from a wireless data frame. The message sequence number is compared against a last-received message sequence number, and a last-delivered message sequence number. The destination address is also compared to a current address. In response to the compares, a decision is made to forward the wireless data frame to the destination address, discard the wireless frame as a duplicate wireless data frame, queue the wireless data frame, or release the wireless data frame to a next protocol layer.

Abstract: The present disclosure relates to systems, methods and compositions for the generation of antibody-producing B cells in vitro. Some embodiments are related to an in vitro system for generating antibody-producing B cells from hematopoietic stem/progenitor cells (HSPCs).

Abstract: The present disclosure discloses a method, apparatus and system for transmitting UE information in a multimedia subsystem. The method includes: a call session control function entity obtains capability information of UE, and transmits the capability information of the UE to an AS; the AS obtaining the capability information of the UE sent from the call session control function entity. The solution of the present disclosure ensures that the AS in the IMS can obtain the capability information of the UE. Therefore, services based on the capability information of the UE can be implemented on the AS successfully.

Abstract: Methods and apparatus for delivering ordered and duplicate-free wireless data frames are generally described and claimed herein. Other embodiments may also be described herein. In an embodiment, a source address, a destination address, and a message sequence number are acquired from a wireless data frame. The message sequence number is compared against a last-received message sequence number and a last-delivered message sequence number. The destination address is also compared to a current address. In response to the compares, a decision is made to forward the wireless data frame to the destination address, discard the wireless frame as a duplicate wireless data frame, queue the wireless data frame, or release the wireless data frame to a next protocol layer.

Abstract: A method, apparatus and system for communicating in a wireless mesh network may relate to a mesh point observing beacon transmissions of one or more neighboring mesh points and dynamically determining if and when to transmit its own beacon based on these observations. Determining when to transmit the beacon may be performed without time synchronization between the one or more neighboring mesh points and be dynamically selected based on the observed transmission time pattern of the neighboring mesh points. Various additional details and embodiments are also disclosed.

Abstract: Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.

Abstract: Methods and compositions are provided for delivery of a polynucleotide encoding a gene of interest, typically an antigen, to a dendritic cell (DC). The virus envelope comprises a DC-SIGN specific targeting molecule. The methods and related compositions can be used to treat patients suffering from a wide range of conditions, including infection, such as HIV/AIDS, and various types of cancers.

Abstract: Network node power management methods and apparatus are generally described herein. Other embodiments may be described and claimed.

Abstract: In a communication device compatible with either a SISO or MIMO access point, a set of antennas is configured as either sector-directional or omni-directional, depending upon whether the communication channel is characterized by the communication device as either strongly line of sight, or strongly scattering, respectively. In some embodiments, for the case in which a MIMO access point is utilized, the singular values of an estimated channel matrix are generated, and based upon the singular values, the characteristics of the communication channel is estimated. Other embodiments are described and claimed.

Abstract: A system and method is provided for remote session control of IP Multimedia Subsystem (IMS) sessions. A remote media flow may be established as part of an origination process wherein the controller UE requests that the media flow is established on a remote media UE as part of the origination request. A remote media flow may also be established as part of a termination process wherein the controller UE identified in the termination request identifies a remote media UE on which a remote media is to be established. Embodiments also allow for the session control to be transferred from a first device to a second device, while maintaining one or more media flows on the first device.

Abstract: Embodiments of methods and apparatus for providing a flow control system for traffic flow in a wireless mesh network based on traffic prioritization are generally described herein. Other embodiments may be described and claimed.

Abstract: A nanostructure and methods of synthesizing same. In one embodiment, the nanostructure includes a magnetic iron oxide nanoparticle, a hydrophobic protection structure including at least an amphiphilic copolymer, wherein the hydrophobic protection structure encapsulates the magnetic iron oxide nanoparticle, and at least one amino-terminal fragment (ATF) peptide or epidermal growth factor receptor (EGFR) antibody conjugated to the amphiphilic copolymer.

Abstract: A nanostructure and methods of synthesizing same. In one embodiment, the nanostructure includes a nanospecies, a hydrophobic protection structure including at least one compound selected from a capping ligand, an amphiphilic copolymer, and combinations thereof, wherein the hydrophobic protection structure encapsulates the nanospecies, and at least one histidine-tagged peptide or protein conjugated to the hydrophobic protection structure, wherein the at least one histidine-tagged peptide or protein has at least one binding site.

Abstract: A media access controller (MAC) for wireless mesh networks comprises a quality-of-service (QoS) manager to monitor consumed bandwidth of a current application flow and to compare the consumed bandwidth with a contracted bandwidth for the current application flow. The MAC also comprises a contention manager to coordinate access to a wireless communication channel for communications with other nodes of the wireless mesh network. The QoS manager instructs the contention manager to employ signaling to request additional resources for the current application flow after the consumed bandwidth is significantly less than the contracted bandwidth.

Abstract: Apparatuses and methods for dynamically adjusting carrier sensing threshold levels in a wireless, such as CSMA, system. A station may use the carrier sensing measurement made in normal CSMA operation to determine a threshold level for the local station, and transmit the determined level to other stations in the system. The station also receives similar information from other stations in the system and determines, based at least in part on the information received and the local determined threshold level, an optimal carrier sensing threshold level.

Abstract: An embodiment of the present invention provides an apparatus, comprising a network interface (NIC) card operable in communication with a mobile platform to monitor network traffic and perform filtering to enable decreased system resource use in said mobile platform when in an Always On Always Connected (AOAC) state.