Abstract: The present disclosure relates to a medical silicon rubber having high mechanical property and a preparation method thereof. The medical silicon rubber comprises the following raw materials in parts by weight: 50˜90 parts of silicon rubber, 10˜50 parts of polyurethane, 10˜50 parts of fillers, 2˜6 parts of hydrogen-containing silicon oil and 2˜5 parts of a vulcanizing agent. The preparation method comprises: evenly mixing a part of fillers with silicon rubber in an internal mixer, and evenly mixing the other part of fillers with polyurethane in the internal mixer; and mixing the mixed polyurethane on an open type rubber refining machine, then successively adding hydrogen-containing silicon oil, the evenly mixed silicon rubber and the vulcanizing agent into the open type rubber refining machine many times by small portions, and finally vulcanizing the mixed rubber on a plate rubber vulcanizing machine for 5˜15 min at 150˜190° C.

Abstract: A cell culture device includes a cell culture circuit, a sensor that is disposed in the cell culture circuit and is configured to measure turbidity of a cell fluid, and a calibration unit. The calibration unit is configured to calculate, as a first concentration, a cell concentration of a culture medium that includes the cell fluid, to calculate, as a second concentration, a cell concentration of a culture medium that includes no cells, and to create a calibration curve for a measurement value of the sensor and the turbidity of the cell fluid by associating the first concentration with a first measurement value for the culture medium that includes the cell fluid and associating the second concentration with a second measurement value for the culture medium that includes no cells.

Abstract: The disclosure discloses construction and application of an engineered strain of E. coli for producing malic acid by fixing CO2, and belongs to the field of fermentation. The engineered strain is obtained by performing genetic engineering transformation on Escherichia coli MG1655; the genetic engineering transformation includes knocking out a fumarate reductase gene, a fumarase gene, a lactate dehydrogenase gene and an alcohol dehydrogenase gene and freely overexpressing a formate dehydrogenase, an acetyl coenzyme A synthetase, an acylated acetaldehyde dehydrogenase, a formaldehyde lyase, a dihydroxyacetone kinase, a malic enzyme and a phosphite oxidoreductase to obtain a strain GH0407. The strain is used for producing malic acid by fermentation, anaerobic fermentation is performed for 72 hours with CO2 and glucose as a co-substrate, the production of malic acid reaches 39 g/L, the yield is 1.53 mol/mol, and accumulation of malic acid in the original strain is not achieved.

Abstract: A robotic device for reducing electromagnetic interference (EMI) noise and suppress leakage current is provided. The robotic device comprises a controller configured to control phase-shift switching of a plurality of axes to reduce electromagnetic interference (EMI) noise and suppress leakage current, an electrical circuit, and a plurality of loads coupled to a plurality of motors of the plurality of axes. The electrical circuit comprises a power source and rectifier; an EMI filter configured to further reduce the EMI noise and suppress the leakage current from the plurality of axes; and the plurality of axes comprising a plurality of drives and a plurality of motors that are configured to operate the plurality of loads.

Abstract: The invention provides a recombinant Escherichia coli strain for producing succinic acid and a construction method thereof. The by-product encoding genes in the E. coli strain FMME-N-2 are knocked out to obtain the E. coli strain FMME-N-5 (?focA-pflB-?ldhA-?pta-ackA); and the phosphoenolpyruvate carboxykinase pck derived from Actinobacillus succinogenes and the phosphite dehydrogenase ptxD derived from Pseudomonas stutzeri were overexpressed. The constructed plasmid pTrcHisA-pck-ptxD was introduced into the expression host E. coli FMME-N-5 (?focA-pflB-?ldhA-?pta-ackA), and the cells were screened in a plate containing ampicillin, to obtain an engineered strain E. coli FMME-N-5 (?focA-pflB-?ldhA-?pta-ackA)-pck-ptxD that can efficiently produce succinic acid. After fermentation by a two-stage fermentation strategy, the production of succinic acid reaches 137 g/L, the yield of succinic acid is up to 1 g/g glucose, and the space time yield is 1.

Abstract: The invention provides a method for preparing pyrrolidone, and the invention provides a method for catalytically preparing pyrrolidone with ?-aminobutyric acid in the presence of carnitine-CoA ligase CaiC. The carnitine-CoA ligase CaiC has an amino acid sequence as shown in SEQ ID NO:1. The ligase has catalytic activity in the cyclization of ?-aminobutyric acid to produce pyrrolidone. The carnitine-CoA ligase provided in the present invention affords a yield of pyrrolidone of 3.26 g/L and a molar yield of 39.53% in 24 h when ?-aminobutyric acid is used as a substrate, thus reducing the production period, improving the production of pyrrolidone, and accelerating the industrialization process of producing pyrrolidone by enzymatic conversion method.

Abstract: The present invention is directed to methods and compositions for the production of Fc-containing polypeptides having improved properties and comprising mutations at positions 243 and 264 of the Fc region.

Abstract: The present disclosure relates to light guides and near-eye display apparatuses. One example light guide includes a light guide plate and a two-dimensional grating that is disposed on a surface of the light guide plate. The two-dimensional grating includes a plurality of grating units arranged in a planar shape, the grating units are arranged at an interval of a first distance along a first direction and at an interval of a second distance along a second direction, and the first direction intersects with the second direction. The two-dimensional grating includes a light egress area and a light ingress area that are arranged along a third direction, and a fourth direction is perpendicular to the third direction.

Abstract: According to an aspect of this disclosure, a circuit includes a voltage source and an output load, first and second resonant modules disposed between the voltage source and the output load, and first and second transformers. The circuit is further arranged such that the first transformer is disposed between the first resonant module and the output load, and the second transformer is disposed between the second resonant module and the output load. The circuit also includes a plurality of half-bridges coupled between the first and second resonant modules and the voltage source. The circuit further includes a voltage divider disposed between the voltage source and the plurality of half-bridges.

Abstract: The present invention provides recombinant Escherichia coli for producing glutarate, a construction method and use thereof. A double-plasmid recombinant bacterium is constructed through molecular biological means for co-expressing an aldehyde synthase (AAS) gene, an amine oxidase Mao (gene) and an aldehyde dehydrogenase (Glox) gene. The constructed expression plasmids are introduced into the Escherichia coli to reconstruct to obtain recombinant cells. A recombination strain for efficiently producing glutarate is obtained through amicillin resistance and kanamycin resistance combined plate screening. Efficient production of the glutarate is achieved by optimizing concentration of a substrate, cell concentration and a transformation temperature. L-lysine with a concentration of 30 g/L may be transformed into 19.

Abstract: The disclosure provides a medical sealant glue capable of promoting wound healing and a preparation method thereof. The medical sealant glue is formed by covalent cross-linking of two components after being physically mixed by a mixing tool, wherein the first component is a nucleophilic component, and the second component is an electrophilic component. The medical sealant glue has a gelation time of 1-10 s, a swelling ratio of 0-100%, a bursting strength of 100-250 mmHg, and a degradation time of 0.5-300 days. The nucleophilic component of the medical sealant glue contains exosome or hyaluronic acid and chitosan, and thus the medical sealant glue not only has the effect of promoting wound healing, but also has antibacterial and anti-infection effects.

Abstract: A self-contained actuator for use in a robot manipulator includes: a housing, in which are arranged in axial sequence a gear, a motor, a brake, a sensor and a motor drive. The motor drive includes wide-bandgap/WBG electronics and is arranged in heat-dissipating relationship with a free end of the housing. Through the motor and some further components, there is provided a central channel for receiving a cable connected to at least one further actuator of the robot manipulator. The channel may be angled or straight. In embodiments where the motor drive is hollow, the central channel extends between the axial ends of the actuator. There is further provided an all-in-one industrial robot comprising a robot manipulator, in which one or more self-contained actuators with the above characteristics are installed and a robot controller is physically integrated.

Abstract: A probe request sent by at least one second router is received. A router to be networked is determined from the at least one second router according to the probe request. A networking request carrying networking matching information is returned to the router to be networked. Wireless access of the first router is enabled. The networking matching information is provided to the router to be networked for networking matching. After the router to be networked has enabled wireless access of the router to be networked based on the networking request, networking is completed by establishing, based on wireless access of the first router and wireless access of the router to be networked, a connection with the router to be networked.

Abstract: The present invention relates to a recombinant strain for producing shikimic acid, in which a target gene that regulates the asymmetric cell division and target genes that regulate the shikimic acid production are expressed The target gene that regulates the asymmetric cell division includes cytoskeletal protein PopZ coding gene popZ, and the target genes that regulate the shikimic acid production include DAHP synthase coding gene aroG, 3-dehydroquinate synthase coding gene aroB, and transketolase coding gene tktA. The recombinant strain of the present invention realizes the de novo synthesis of shikimic acid using glucose as a substrate, with a low cost. After fermentation with the strain in a 7.5 L fermentor, the highest production of shikimic acid is 88.1 g/L, the yield is 0.33 g/g, and the production intensity of shikimic acid is 1.1 g/L/h.

Abstract: A first network node having gained access to a preset network receives a probe message broadcast by a second network node seeking access to the preset network. The probe message carries a second Internet Protocol (IP) address of the second network node. If the probe message includes a configuration mechanism identifier, the first network node unicasts a reply message of the probe message to the second network node based on the second IP address. The reply message carries a first IP address of the first network node. The first IP address is configured for establishing a network communication channel between the second network node and the first network node. The first network node sends network configuration information to the second network node through the network communication channel. The network configuration information is configured to allow the second network node to access the preset network.

Abstract: Disclosed is an aromatic compound. Such compounds can locally produce a long-lasting nerve blocking effect, have an analgesic effect, an anti-pruritic effect, etc., and can be used in the preparation of a long-acting local anaesthetic drug, a local analgesic drug and an anti-pruritic drug.

Abstract: An access method is provided for an access point (AP). The method is applied to a first AP, and includes: responsive to determining that an access restriction rule allows a second AP to access the first AP, interface configuration information of the first AP is determined according to the access restriction rule; and an access interface of the first AP is configured according to the interface configuration information, where the access interface is configured for the second AP to access the first AP in response to determining that the access interface is configured to allow access.

Abstract: A magnet coil for magnetic Czochralski single crystal growth includes: a first coil, a second coil, and an auxiliary coil arranged between the first coil and the second coil. A distance between the first coil and a first edge of the auxiliary coil close to the first coil is equal to a distance between the second coil and a second edge of the auxiliary coil close to the second coil. The auxiliary coil, the first coil and the second coil have a common central axis. When being energized, a direction of a current in the first coil is opposite to a direction of a current in the second coil, and a magnetic field generated by a current in the auxiliary coil is used for enhancing a cusp magnetic field between the first coil and the second coil.

Abstract: A first network node having gained access to a preset network receives a probe message broadcast by a second network node seeking access to the preset network. The probe message carries a second Internet Protocol (IP) address of the second network node. If the probe message includes a configuration mechanism identifier, the first network node unicasts a reply message of the probe message to the second network node based on the second IP address. The reply message carries a first IP address of the first network node. The first IP address is configured for establishing a network communication channel between the second network node and the first network node. The first network node sends network configuration information to the second network node through the network communication channel. The network configuration information is configured to allow the second network node to access the preset network.

Abstract: An access method is provided for an access point (AP). The method is applied to a first AP, and includes: responsive to determining that an access restriction rule allows a second AP to access the first AP, interface configuration information of the first AP is determined according to the access restriction rule; and an access interface of the first AP is configured according to the interface configuration information, where the access interface is configured for the second AP to access the first AP in response to determining that the access interface is configured to allow access.