Patents by Inventor Lin Ai

Lin Ai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compostions for enhancing transdermal drug delivery
    Patent number: 8062663
    Abstract: Methods and compositions for enhancing transdermal delivery of a bioactive agent. The method contains the step of applying to a skin tissue an effective amount of a composition comprising: (a) a drug vehicle; (b) a bioactive agent encapsulated within the drug vehicle; (c) a plurality of proteolytic enzyme molecules conjugated onto the surface of the drug vehicle; and (d) a pharmaceutically acceptable carrier, for a period of time effective to deliver the bioactive agent across the skin tissue at a desired dosage.
    Type: Grant
    Filed: May 14, 2009
    Date of Patent: November 22, 2011
    Assignee: National Health Research Instittues
    Inventors: Yu-Jing Wang, Yu-Chao Wang, Yi-Ting Wu, Lin-Ai Tai, Leu-Wei Lo, Chung-Shi Yang
  • PROCESS FOR PREPARING OPTICAL PURE MILNACIPRAN AND ITS PHARMACEUTICALLY ACCEPTED SALTS
    Publication number: 20100016636
    Abstract: The present invention discloses a process for preparing optically pure milnacipran and their pharmaceutically acceptable salts, which adopts racemic milnacipran as starting material, tartaric acid derivatives and their compositions as resolving agents to resolve.
    Type: Application
    Filed: November 28, 2007
    Publication date: January 21, 2010
    Inventors: Lin Ai, Xiao Liu
  • METHODS AND COMPOSTIONS FOR ENHANCING TRANSDERMAL DRUG DELIVERY
    Publication number: 20090291133
    Abstract: Methods and compositions for enhancing transdermal delivery of a bioactive agent. The method contains the step of applying to a skin tissue an effective amount of a composition comprising: (a) a drug vehicle; (b) a bioactive agent encapsulated within the drug vehicle; (c) a plurality of proteolytic enzyme molecules conjugated onto the surface of the drug vehicle; and (d) a pharmaceutically acceptable carrier, for a period of time effective to deliver the bioactive agent across the skin tissue at a desired dosage.
    Type: Application
    Filed: May 14, 2009
    Publication date: November 26, 2009
    Applicant: NATIONAL HEALTH RESEARCH INSTITUTES
    Inventors: Yu-Jing WANG, Yu-Chao Wang, Yi-Ting Wu, Lin-Ai Tai, Leu-Wei Lo, Chung-Shi Yang
  • Drug Release from Thermosensitive Liposomes by Applying an Alternative Magnetic Field
    Publication number: 20090004258
    Abstract: Thermosensitive liposomes encapsulating paramagnetic iron oxide nanoparticles are used as a drug controlled release system. Paramagnetic iron oxide nanoparticles are used to generate heat by applying alternative magnetic field to cause leakage of drugs in the liposomes.
    Type: Application
    Filed: May 30, 2008
    Publication date: January 1, 2009
    Applicant: National Health Research Institutes
    Inventors: Chung-Shi Yang, Leu-Wei Lo, Lin-Ai Tai
  • Use of ubenimex and the pharmaceutical composition containing it for treating virus hepatitis
    Patent number: 6245813
    Abstract: The present invention relates to the use of Ubenimex or salts thereof and the pharmaceutical composition containing them for the treatment of virus hepatitis, espcially chronic hepatitis B.
    Type: Grant
    Filed: March 19, 1998
    Date of Patent: June 12, 2001
    Assignee: Sichuan Industrial Institute of Antibiotics
    Inventors: Shanxue Zhou, Lin Ai, Ping Wang, Chuanhua Ye, Mingxiu Peng