Abstract: In a method for producing acetoin, butanediol, or butanol from ethanol according to the present invention, a cell-free catalysis method was used by designing an artificial synthetic pathway so that proteins of NOX, EtDH, FLS, BDH, and DDH and variant proteins thereof exhibit cascade catalytic activity as enzymes. Compared to existing fermentation methods using microorganisms, the production method according to the present invention does not require cell growth and has a short synthetic pathway, a fast reaction rate, high yield and productivity, adjustment of targeted reaction conditions is convenient, and butanol may be effectively produced. Moreover, same may be reused numerous times by fixing the proteins to nano-particles, and are also effective for producing acetoin, butanediol, or butanol, thus being economical. Therefore, the production method may be usefully adopted in the relevant industries requiring acetoin, butanediol, or butanol.

Abstract: Provided herein, inter alia, are methods of using bispecific antibody compounds which may bind immune cells and are, inter alia, useful for treating cancers. Anti-tumor antigen antibodies are connected to anti-immune antibodies through their hinge regions using, for example, click chemistry to form dual-specific, bivalent BiTES with high in vivo tumor targeting ability and tumor cytotoxicity.

Abstract: An energy storage system includes a battery cluster, a battery control system, at least two first power conversion modules, a bus, and a second power conversion module. A plurality of battery packs in the battery cluster are connected in parallel to the bus through the at least two first power conversion modules, one end of the second power conversion module is connected in parallel to the battery cluster, and the other end of the second power conversion module is connected to a load or a power grid. The battery control system obtains a target current value that needs to be provided by the second power conversion module to the load or the power grid. In this application, the battery parameters of the battery packs can be equalized, or the battery cluster is enabled to output the target power, so that system stability is improved.

Abstract: The present invention falls within the technical field of medicine, and in particular relates to PDE9 inhibitor compounds as shown in formula (I) or pharmaceutically acceptable salts or stereoisomers thereof, and also relates to pharmaceutical preparations and pharmaceutical compositions of the compounds and the uses thereof. X1, X2, X3, X4, R1, R2, ring A, L and m are as defined in the description. The compounds can be used to prepare drugs for treating or preventing related diseases mediated by PDE9.

Abstract: A pavement laying method and a polyurethane pavement coating are provided. The pavement laying method includes: providing a solid particle material; mixing a polyester polyol material and an isocyanate material into the solid particle material to form a mixed slurry; and laying the mixed slurry onto a pavement and solidifying the mixed slurry, so as to form a polyurethane pavement coating on the pavement. In addition, at least one of the polyester polyol material and the isocyanate material is derived from biomass resources.

Abstract: A mussel bionic gel composition includes: a mussel bionic copolymer and/or a mussel bionic compound, a cross-linking agent and water, wherein the mussel bionic copolymer includes a structural unit A from a vinyl monomer and a structural unit B from a vinyl-containing mussel bionic catechol group monomer; and the mussel bionic compound includes polyacrylamide and a mussel bionic catechol compound. The self-growth gel particle profile control and water plugging agent prepared from the composition is low in initial apparent viscosity, easy to inject and far in migration, has good shear repairing performance and is particularly applicable to a low-permeability fractured reservoir, thereby adjusting a micro-fracture network, improving a fracture channel and increasing waterflood efficiency and recovery efficiency.

Abstract: Disclosed is a hardware-based protection group switching method and optical communication equipment.

Abstract: Provided is a chimeric hemagglutinin (HA) protein including an HA1 subunit and an HA2 subunit, in which the HA1 subunit is composed of a first domain derived from a parental HA1 subunit of a first subtype influenza virus and a second domain derived from a parental HA1 subunit of a second subtype influenza virus. The chimeric HA protein has improved thermal stability and can be used in a vaccine composition for preventing influenza virus infection. Also provided is a method of inducing an immune response against an influenza virus in a subject in need thereof that includes administering the chimeric HA protein to the subject, thereby conferring protection against the influenza virus infection on the subject.

Abstract: Disclosed are an electronic pen, a method and a device for controlling an electronic pen, and a computer-readable storage medium. The method includes: obtaining state information of the electronic pen; and determining a time for the electronic pen to send coding signal frequency information according to the state information, and controlling the electronic pen to send the coding signal frequency information when reaching the time, to reduce an energy consumption of the electronic pen.

Abstract: An antigen and antibodies prepared based on peptidylarginine deiminase (PADI4) serving as a tumor marker, and application thereof are disclosed. The antigen has an amino acid sequence shown as SEQ ID NO. 1. Specific antibodies prepared by using the antigen are also disclosed. The protein PADI4 monoclonal antibodies include a protein PADI4 monoclonal antibody coated onto an ELISA plate and a biotin-labeled protein PADI4 monoclonal antibody. A kit prepared by using the antibodies of the present disclosure can effectively and stably determine a protein PADI4 level of a human serum, and has a broad spectrum, detectability, and high test repeatability.

Abstract: An abnormal packet detection apparatus and method are provided. The abnormal packet detection apparatus stores a whitelist corresponding to a protocol port, wherein the whitelist includes at least one legal packet record. Each legal packet record includes a legal packet length, a legal source address, and a legal variation position set, and corresponds to a reference packet. The abnormal packet detection apparatus determines that a current packet length and a current source address of a to-be-analyzed packet are respectively the same as the legal packet length and the legal source address of a reference packet record among the at least one legal packet record, determines a current variation position of the to-be-analyzed packet by comparing the to-be-analyzed packet with the reference packet corresponding to the reference packet record, and generates a detection result by comparing the current variation position with the legal variation position set of the reference packet record.

Abstract: The invention relates to a decorative surface covering element, in particular a floor panel, ceiling panel or wall panel. The invention also relates to a panel covering, such as a floor covering, ceiling covering or wall covering, comprising a plurality of panels according to the invention. The invention further relates to a method of producing a decorative surface covering element according to the invention.

Abstract: The invention relates to a decorative panel, in particular a floor panel, ceiling panel or wall panel. The invention also relates to a panel covering, such as a floor covering, ceiling covering or wall covering, comprising a plurality of panels according to the invention. The invention further relates to a method of producing a decorative panel according to the invention.

Abstract: A converter system includes a plurality of converters, a sampling circuit, and a control circuit. The plurality of converters are connected in parallel. Each converter includes a detection circuit which includes a first switch and at least two resistors. The first switch is connected in parallel with one of the at least two resistors. The control circuit control the sampling circuit to collect a first voltage and a second voltage, where the first voltage is a voltage that is between a second bus and a ground cable and that is collected by the sampling circuit when first switches in detection circuits of a first quantity are in a turn-on state, the second voltage is a voltage that is between the second bus and the ground cable and that is collected by the sampling circuit when first switches in detection circuits of a second quantity are in a turn-on state.

Abstract: A voltage source inverter includes a bus capacitor, a bidirectional power tube, a filter inductor, and a filter capacitor. A voltage control method includes: respectively obtaining a first feedback current and a first feedback voltage from an output end of the filter inductor and an output end of the filter capacitor; obtaining a first duty cycle and a second duty cycle based on the first feedback current, a maximum current reference value, and a minimum current reference value in a current loop; obtaining a third duty cycle based on the first feedback voltage and a voltage reference value in a voltage loop; and selecting one of the first duty cycle, the second duty cycle, and the third duty cycle, and controlling the bidirectional power tube, so that a duty cycle of the bidirectional power tube is between the first duty cycle and the second duty cycle.

Abstract: Disclosed are a M-cell targeting and pH-responsive starch-based carrier material, and a preparation method and application thereof. The starch-based carrier material has a molecular structure as follows, a molecular weight of 7.04×104 to 2.11×106 g/mol, a degree of substitution of carboxymethyl groups of 0.04 to 0.28, and a grafting amount of targeting peptide GRGDS of 0.01% to 1.12% (calculated based on the content of N). The material is not dissolved in water when protonated at pH (pH=1.2) of the stomach, and is slowly dissolved in water when deprotonated at pH (pH=6.8) of the small intestine, therefore it has good responsiveness to pH of the gastrointestinal tract. The material can efficiently encapsulate a positively charged active substance by means of electrostatic interaction, therefore it can protect the active substances from being destroyed and inactivated in the gastrointestinal tract.

Abstract: A semiconductor connection structure and its manufacturing method are provided. The semiconductor connection structure includes a substrate with an array area, a first trench, a metal line, a work function layer and a contact structure. The array area includes a central region and an edge region surrounding the central region. The first trench is formed in the substrate and extends from the central region to the edge region along a first direction. The first trench has a first portion in the central region and a wider second portion in the edge region. The metal line and the work function layer are formed in the first trench. The contact structure is formed in the first trench within the edge region. The contact structure is located on the metal line and in direct contact with the metal line. The bottom portion of the contact structure is surrounded by the work function layer.

Abstract: A memory device includes a substrate and an eFuse structure. The substrate includes an array region and an eFuse region and the eFuse region of the substrate has an eFuse trench. The eFuse structure includes a first gate oxide layer, a plurality of doped regions, a dummy buried word line, and an eFuse gate electrode. The first gate oxide layer is conformally formed on a surface of the eFuse trench. The doped regions are respectively formed in the substrate on opposite sides outside the eFuse trench, and in contact with the first gate oxide layer. The dummy buried word line is formed on the first gate oxide layer. The eFuse gate electrode is formed on the dummy buried word line and in contact with the first gate oxide layer. The dummy buried word line is electrically isolated from the eFuse gate electrode.

Abstract: A method, an apparatus, device, and a computer-readable storage medium for processing information are provided. The method is used in a first network device, and includes receiving information related to a second network device, determining a first resource configuration corresponding to a coverage classification related to the second network device based on the information, and transmitting the first resource configuration to the second network device. The method may obtain the first resource configuration through making prediction and calculation analysis based on the information, which may achieve dynamic configurations of different coverage classifications, save energy consumption, and improve system capacity and performance at the same time.

Abstract: A system and method is provided for monitoring the fetal position and/or orientation of the fetus of an expectant mother. An acoustic sensor array is positioned over the belly. The pattern of acoustic sensor signals is processed to determine a fetal orientation and/or to determine movement over time of the fetus.