Abstract: The present disclosure provides a pharmaceutical composition comprising a Bcl-2/Bcl-xL inhibitor, a chemotherapeutic agent, and a pharmaceutically acceptable carrier. The present disclosure also provides a method of treating cancer, comprising administering to a subject in need thereof a therapeutically effective amount of a Bcl-2/Bcl-xL inhibitor and a therapeutically effective amount of a chemotherapeutic agent. The present disclosure also provides use of a combination of a Bcl-2/Bcl-xL inhibitor and a chemotherapeutic agent in the manufacture of an anti-tumor medicament. In the present disclosure, a significantly enhanced anti-tumor effect can be achieved by administration of a Bcl-2/Bcl-xL inhibitor in combination with a chemotherapeutic agent.

Abstract: Disclosed is a steering wheel torque feedback optimization control method for a differential braking system, including: estimating a tire lateral force of a vehicle; predicting a state of the vehicle at a next moment under a non-differential torque condition; predicting a state of the vehicle at the next moment under a differential torque condition with an additional yaw moment; calculating tire lateral forces at the next moment under the differential torque condition and the non-differential torque condition separately based on the predicted states of the vehicle at the next moment under the differential torque condition and the non-differential torque condition, and obtaining a predicted one-step change value of a front tire lateral force by performing subtraction; performing integral calculation based on time, and obtaining a continuous change amount of the tire lateral force; and correcting a desired moment of a steering power motor.

Abstract: A method for smelting low-phosphorus high-manganese steel based on reduction dephosphorization of ferromanganese is provided in the present application, relating to the technical field of high-manganese steel smelting, where the dephosphorization of ferromanganese is carried out under reducing atmosphere conditions through mediate-frequency induction furnace to obtain molten ferromanganese with lower phosphorus content, which is subsequently mixed with low phosphorus molten steel obtained by smelting in oxidative period of electric arc furnace in LF ladle refining furnace to make the Mn content of steel reach the requirement of high-manganese steel, and smelting is carried out under the condition of reducing atmosphere by adjusting the composition and temperature of the molten steel to meet the requirements of the target composition of the steel grade before tapping the steel.

Abstract: Embodiments herein provide methods of monitoring temperatures of fluid delivery conduits for delivering fluids to, and other components external to, a processing volume of a processing chamber used in electronic device fabrication manufacturing, and monitoring systems related thereto. In one embodiment, a method of monitoring a processing system includes receiving, through a data acquisition device, temperature information from one or more temperature sensors and receiving context information from a system controller coupled to a processing system comprising the processing chamber. Here, the one or more temperature sensors are disposed in one or more locations external to a processing volume of a processing chamber. The context information relates to instructions executed by the system controller to control one or more operations of the processing system.

Abstract: A coordinated control method for electric vehicles having independent four-wheel driving and steering, comprising the steps of: calculating to obtain a desired value of yaw velocity according to the steering angle and the current vehicle driving speed, and limiting the desired value of yaw velocity according to the current road adhesion condition; constructing an optimization problem according to the current vehicle motion state and the desired value of yaw velocity, and solving the optimization problem to obtain a desired active rear wheel steering angle control variable and a desired additional yaw moment control variable; calculating to obtain an additional torque of each wheel according to a desired additional yaw moment control variable, obtaining a desired active rear wheel steering angle, and sending the additional torque of each wheel and the desired active rear wheel steering angle to an executor of the vehicle for performing a coordinated control.

Abstract: In a method of manufacturing a lithographic mask of an integrated circuit for semiconductor device manufacturing an optical proximity correction (OPC) process to a layout pattern of the integrated circuit is performed to produce a corrected layout pattern. An inverse lithographic technology (ILT) process to the corrected layout pattern is also performed to enhance the corrected layout pattern to produce an OPC-ILT-enhanced layout pattern of the lithographic mask. A first contour image associated with the OPC-ILT-enhanced layout pattern is generated when the OPC-ILT-enhanced layout pattern of the lithographic mask is projected on a wafer. The features of the generated first contour image are extracted. And a second contour image of a developed photo resist pattern on the wafer associated with the OPC-ILT-enhanced layout pattern as an output of a deep neural network is generated.

Abstract: Methods and systems are provided for differentiating an XR device from other devices when initiating communications with an Internet gateway. Initially the XR device sends a probe request to the Internet gateway, where the probe request includes an identifier of the device type and network requirements of the XR device. It is determined that the particular device type and network requirements in the probe request are supported by the Internet gateway, and is communicated to the XR device in the form of a probe response. A communication session is set up between the XR device, the Internet gateway, and a network, the communication session including QoS control based on the device type and network requirements of the XR device.

Abstract: This disclosure relates to a lipid-based topical injection formulation containing a Long-Acting SusTained delivering lipid, a structured lipid, a polymer-conjugated lipid and an ionizable lipid, and optionally a neutral phospholipid. The lipid-based topical injection formulation enables enriched delivery of drugs at an injection site and efficient expression of proteins for a prolonged period of time. This disclosure also relates to a method of preparing the lipid-based topical injection formulation, and use of the lipid-based topical injection formulation in the delivery of biologically active substances such as nucleic acids (e.g., mRNA, miRNA, siRNA, saRNA, ASO, DNA, etc.).

Abstract: An aluminum alloy metro vehicle body section bar capable of matching and combining includes a roof section bar, an upper edge beam section bar, a side wall section bar, a lower edge beam section bar and a floor section bar, wherein the roof section bar comprises roof edge section bars of two widths; the upper edge beam section bar comprises an upper edge beam of a drum-shaped vehicle and an upper edge beam 4b of the trapezoidal vehicle; the side wall section bar comprises a side wall middle section bar of the drum-shaped vehicle and a side wall middle section bar of the trapezoidal vehicle; the lower edge beam section bar comprises a lower edge beam of the drum-shaped vehicle and a lower edge beam of the trapezoidal vehicle; and the floor section bar comprises underframe edge section bars of two widths.

Abstract: Provided herein is a class of ionizable lipid compounds represented by formula ((IV?), or pharmaceutically acceptable salts, isotopic variants, tautomers or stereoisomers thereof. Also provided is a nanoparticle pharmaceutical composition comprising said compound, and the application of said compound and its composition in the delivery of nucleic acids.

Abstract: A tamper-proof screw includes a main body, a pin body, a ball, and at least one abutting member. A through hole is provided in the main body. The pin body is movably disposed in the through hole. The ball is located in the through hole. The abutting member is located in the through hole and has a connecting end and a free end opposite to each other. The connecting end is disposed on an inner wall of the main body and located between the ball and the free end. The ball is located between the pin body and the abutting member. When the pin body moves in the through hole to push the ball to press against the connecting end of the abutting member, the abutting member pivots around the connecting end to allow the free end to extend outwards from the main body.

Abstract: A batching system for producing special cables includes a motor, a loading plate, wire pulling rollers, a transmission steel pipe and a batching motor; the transmission steel pipe is rotatably connected to an upper end surface of the loading plate by a bracket; the motor is fixedly arranged on a side wall of a mounting bracket; the wire pulling rollers are rotatably connected to an upper end surface of the loading plate; the system further includes: a wiring mechanism, a replacing mechanism and a driving mechanism; the wiring mechanism is coaxially and fixedly connected with an outer end surface of the transmission steel pipe; the replacing mechanism is sleeved on the outer end surface of the transmission steel pipe; the driving mechanism is fixedly mounted on a lower end surface of the loading plate; a winding mechanism for winding wires is coaxially and fixedly arranged on the transmission steel pipe.

Abstract: A user equipment (UE) configured to provide a service type indicator in a user assistance information (UAI) message to a base station of a telecommunication network is described herein. The service type indicator indicates a type of a network-using service active on the UE. A base station, as also described herein, then takes action based on resources available to the base station and on the service type indicator received from the UE in the UAI message.

Abstract: The present disclosure relates to an information transmission method, a sharing end, a server and an electronic apparatus. The method includes: obtaining target transmitted information of a target webpage; modifying first description information of the target webpage into target description information according to the target transmitted information, wherein the target description information includes the target transmitted information and the first description information; controlling a target application to read the target transmitted information through a system application program interface API to obtain target information.

Abstract: The disclosure provides a method for delivering an agent to posterior segment of an eye comprising administrating a pharmaceutical composition comprising the agent and mesoporous silica nanoparticles to the eye. An eye drop and a method for treating an ocular disease in a subject in need of such treatment are also provided.

Abstract: A display panel including pixel circuits each including a drive transistor and a first reset transistor; first signal line including an indirect-connection signal line and a direct-connection signal line; connection signal lines, at least part of which is electrically connected to the indirect-connection signal lines; anodes; a pixel circuit group including two pixel circuits at least partially symmetric and adjacent, the first reset transistors of two pixel circuits being adjacent to each other, and adjacent first reset transistors being connected through a first semiconductor connection line, which is connected to the reset signal line; and pixel columns, two sides of the drive transistors in a pixel column being provided with two first signal lines and two second connection signal lines. At least part of the anodes overlaps with adjacent first signal lines and/or two adjacent second connection signal lines.

Abstract: A method for cultivating a Tung tree seedling through hypocotyle grafting includes selection of a sand storage time of a rootstock (Vernicia montana Lour.) seed, seedbed construction, scion collection, scion cutting, rootstock cutting, bandaging, transplantation and management, and the like. A grafted plant obtained by a traditional grafting method (bud grafting) for Tung tree is easy to break at a grafting interface; and when the stem grafting is conducted, because a scion is thick, a rootstock for grafting must be cultivated one year in advance. These grafting methods have production problems such as long cycle and high cost, which can be solved by the present disclosure. The present disclosure has a short rootstock cultivation time, simple grafting operations, a high grafting efficiency, and a high survival rate, greatly shortens a cycle of asexual propagation-based seedling cultivation for Tung tree.

Abstract: Embodiments herein provide methods of monitoring temperatures of fluid delivery conduits for delivering fluids to, and other components external to, a processing volume of a processing chamber used in electronic device fabrication manufacturing, and monitoring systems related thereto. In one embodiment, a method includes receiving, at the temperature monitoring system (TMS) controller, information from a first plurality of temperature sensors and a second plurality of temperature sensors, comparing, using the TMS controller, the temperature information to one or more pre-determined control limits, and communicating, using the TMS controller, an out-of-control event to a user. Generally, the temperature monitoring system features the first and second pluralities of temperature sensors, the TMS controller, a first connection module, and a second connection module.