Patents by Inventor Ling Chen

Ling Chen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260145158
    Abstract: Disclosed is an application of a magnetic carboxyl-functionalized covalent organic framework composite as a magnetic solid-phase extraction adsorbent. The preparation method for this composite comprises the following steps: (1) firstly, taking dopamine hydrochloride as a coordinating stabilizer, and synthesizing surface-aminated magnetic iron oxide particles by coprecipitating iron (III) chloride and iron (II) chloride; and (2) then activating the surface-aminated magnetic iron oxide particles, and performing covalent cross-linking on the surfaces of the aminated magnetic iron oxide particles by taking 1, 3, 5-triformylphloroglucinol (Tp) and 4, 4?-diamino-biphenyl-2, 2?-dicarboxylic acid as building blocks, acting under the reversible catalytic action of acetic acid and using a solvothermal synthesis method, so as to prepare the magnetic carboxyl-functionalized covalent organic framework composite.
    Type: Application
    Filed: November 4, 2022
    Publication date: May 28, 2026
    Applicants: SOUTH CHINA UNIVERSITY OF TECHNOLOGY, SCUT-ZHONGSHAN INSTITUTE OF MODERN INDUSTRIAL TECHNOLOGY
    Inventors: Xiaoxi LI, Tianxing WANG, Wei LIU, Ling CHEN, Bing LI
  • Publication number: 20260028256
    Abstract: A treatment agent for water quenching and slag flushing of a yellow phosphorus slag using reverse osmosis concentrate (ROC) and a preparation method thereof are provided. The treatment agent for water quenching and slag flushing of the yellow phosphorus slag using ROC includes the following components in mass percentage: 3% to 10% of a dispersant, 1% to 3% of a wetting agent, 3% to 10% of a scale inhibitor, 3% to 8% of a carbon steel corrosion inhibitor, 0.5% to 1% of a copper corrosion inhibitor, 5% to 25% of a complex cleaning agent, and water as a balance.
    Type: Application
    Filed: November 21, 2024
    Publication date: January 29, 2026
    Applicant: Guizhou Education University
    Inventors: Mingsen DENG, Hengxiu YANG, Hujun SHEN, Xuefeng ZOU, Fushao LI, Qingqing WU, Ling CHEN
  • Patent number: 12516131
    Abstract: The present invention provides a method of preventing, reducing or attenuating acute kidney injury in a subject at risk of experiencing a transient increase in kidney ischemia or hypoxia, comprising administering to the subject an effective amount of an agent that binds to and neutralizes endogenous ouabain (EO).
    Type: Grant
    Filed: December 4, 2020
    Date of Patent: January 6, 2026
    Assignee: UNIVERSITY OF MARYLAND, BALTIMORE
    Inventors: Mordecai P. Blaustein, John Hamlyn, Stephen Gottlieb, Ling Chen
  • Patent number: 12481210
    Abstract: The disclosure provides a new field sequential single LCD projector, includes an LED light source, a collecting and collimating device, a light-combining and color-filtering device, an intermediate reflector, a focusing device, a light-homogenizing device, an outgoing lens, a LCD light valve, a field lens, an imaging reflector and a projection lens which are arranged in sequence according to the light traveling direction. The LED light source includes a red light source, a green light source and a blue light source. Compared with the existing full-color light valve technology, under the same technical condition, the efficiency of the light valve is greatly improved, the power of the light source is greatly reduced, and the image color gamut is greatly improved, so that the projector can output higher brightness and has vast market adaptability.
    Type: Grant
    Filed: November 30, 2022
    Date of Patent: November 25, 2025
    Assignee: Changsha Pujiade Photoelectric Technology Co., Ltd
    Inventor: Ling Chen
  • Patent number: 12447212
    Abstract: Disclosed are a M-cell targeting and pH-responsive starch-based carrier material, and a preparation method and application thereof. The starch-based carrier material has a molecular structure as follows, a molecular weight of 7.04×104 to 2.11×106 g/mol, a degree of substitution of carboxymethyl groups of 0.04 to 0.28, and a grafting amount of targeting peptide GRGDS of 0.01% to 1.12% (calculated based on the content of N). The material is not dissolved in water when protonated at pH (pH=1.2) of the stomach, and is slowly dissolved in water when deprotonated at pH (pH=6.8) of the small intestine, therefore it has good responsiveness to pH of the gastrointestinal tract. The material can efficiently encapsulate a positively charged active substance by means of electrostatic interaction, therefore it can protect the active substances from being destroyed and inactivated in the gastrointestinal tract.
    Type: Grant
    Filed: November 28, 2019
    Date of Patent: October 21, 2025
    Assignee: SOUTH CHINA UNIVERSITY OF TECHNOLOGY
    Inventors: Xiaoxi Li, Yiping Zhang, Ling Chen, Lin Li
  • Publication number: 20250304555
    Abstract: Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFN?, by acting on Tyk-2 to cause signal transduction inhibition.
    Type: Application
    Filed: June 11, 2025
    Publication date: October 2, 2025
    Applicant: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Chunjian LIU, Michael G. YANG, Zili XIAO, Ling CHEN, Ryan M MOSLIN, John S TOKARSKI, David S WEINSTEIN, Stephen T WROBLESKI
  • Patent number: 12422737
    Abstract: The present invention discloses a heat reflection light valve of an LCD (Liquid Crystal Display) projector and a projector. The heat reflection light valve comprises an upper glass substrate, a lower glass substrate and a liquid crystal box clamped between the upper glass substrate and the lower glass substrate, and a TFT (Thin Film Transistor) array is produced on the lower glass substrate; and a CF (Color Filter), a BM (Black Matrix), an OC (Over Coater), a transparent electrode and a post spacer are produced on the upper glass substrate. A layer of reflection film for reflecting blue light is produced on the inner surface of the upper glass substrate, and the reflection film is not produced in a region corresponding to a blue filter matrix of the CF.
    Type: Grant
    Filed: October 21, 2022
    Date of Patent: September 23, 2025
    Assignee: Changsha Pujiade Photoelectric Technology Co., Ltd
    Inventor: Ling Chen
  • Patent number: 12422740
    Abstract: A projector with a thermal superconducting material for heat dissipation is disclosed. The projector includes a projector housing, and an optical machine shell, a thermal superconducting material heat dissipation apparatus, an outer fan, an inner circulation fan, a projection light source and an LCD light valve. The thermal superconducting material heat dissipation apparatus includes a light source radiator and an optical machine heat exchanger. The outer fan performs air draft for the light source radiator. An inner circulation air duct is arranged inside the optical machine shell. The inner circulation fan, the LCD light valve and a heat absorption fin set are arranged in the inner circulation air duct. A heat dissipation ventilation duct is defined between an inner wall of the projector housing and an outer wall of the optical machine shell.
    Type: Grant
    Filed: November 17, 2022
    Date of Patent: September 23, 2025
    Assignee: Changsha Pujiade Photoelectric Technology Co., Ltd
    Inventor: Ling Chen
  • Patent number: 12406026
    Abstract: The embodiments of the present disclosure disclose a computer-implemented method, computer system and a computer program product for detecting and predicting an abnormal log event. In the method, a current event cluster from a plurality of event clusters for a log line in a log file is determined. The plurality of event clusters include at least one abnormal event cluster. Then, a time of event transition from the current event cluster to at least one abnormal event cluster is predicted.
    Type: Grant
    Filed: June 30, 2021
    Date of Patent: September 2, 2025
    Assignee: International Business Machines Corporation
    Inventors: Yi Ming Wang, Hui Dong, Zhong Fang Yuan, Tong Liu, Yan Fen Liu, Ling Chen
  • Patent number: 12365667
    Abstract: Compounds having the following formula I: or a stereoisomer or pharmaceutically-acceptable salt thereof, where R1, R2, R3, R4, and R5 are as defined herein, are useful in the modulation of IL-12, IL-23 and/or IFN?, by acting on Tyk-2 to cause signal transduction inhibition.
    Type: Grant
    Filed: September 5, 2023
    Date of Patent: July 22, 2025
    Assignee: Bristol-Myers Squibb Company
    Inventors: Chunjian Liu, Michael G. Yang, Zili Xiao, Ling Chen, Ryan M. Moslin, John S. Tokarski, David S. Weinstein, Stephen T. Wrobleski
  • Patent number: 12325872
    Abstract: This invention provides acid decarboxylase-prion subunit fusion polypeptides, nucleic acid sequences, expression vectors, and host cells expression such fusion polypeptides to produce various amino acids and derivatives of the amino acids such as polyamines.
    Type: Grant
    Filed: April 13, 2023
    Date of Patent: June 10, 2025
    Assignees: CATHAY BIOTECH INC., CIBT America Inc.
    Inventors: Howard Chou, Ling Chen, Wenqiang Lu, Xiucai Liu
  • Patent number: 12313963
    Abstract: The present disclose discloses a micro-display optical engine including a micro-LED panel, a coolant, a thin lens, a metal frame, a connecting pillar and a projection lens; the micro-LED panel comprises a substrate, a number of pixel light-emitting micro-LED grains, a glass plate, a metal bracket, a sealing frame, a radiator, a filling adhesive and a transparent heat-conducting adhesive. The present disclose also discloses a single-engine, dual-engine and three-engine full-color projector. The present disclose has remarkable features such as relatively simple production, the ability to achieve preliminary productization, excellent thermal stability of heat dissipation, high contrast and color gamut, laying a certain foundation for the actual productization of the new micro-LED micro-display projection technology.
    Type: Grant
    Filed: December 29, 2022
    Date of Patent: May 27, 2025
    Assignee: Changsha Pujiade Photoelectric Technology Co., Ltd
    Inventors: Ling Chen, Rao Chen, Yating Pan, Jie Wang
  • Publication number: 20250154049
    Abstract: Methods of forming a foldable apparatus can involve contacting an existing first major surface of a foldable substrate with an alkaline solution to remove an outer layer to form a new first major surface. In aspects, the alkaline solution comprises about 10 weight % or more of a hydroxide-containing base and/or a pH of about 14 or more. Methods of forming a foldable apparatus can comprise contacting a first major surface of a foldable substrate with a first alkaline detergent solution under sonication. Methods of forming a foldable apparatus can comprise contacting an existing first major surface of a foldable substrate with an acidic solution having a pH from about 3.3 to about 3.5 and a fluorine-containing compound. Methods of forming a foldable apparatus can comprise contacting an existing first major surface of a foldable substrate with a solution comprising fluorosilicic acid.
    Type: Application
    Filed: February 27, 2023
    Publication date: May 15, 2025
    Inventors: Indrani Bhattacharyya, Ling Chen, Wanghui Chen, Jiangwei Feng, Sushmit Sunil Kumar Goyal, Yuhui Jin, Peter Joseph Lezzi, Yousef Kayed Qaroush
  • Publication number: 20250144706
    Abstract: The invention provides a method of producing a cold compactible metallic powder, the method comprising: providing (i) a first metallic powder comprising large metal particles and (ii) a second metallic powder comprising small metal particles, wherein the d50 particle size of the second metallic powder is less than the d50 particle size of the first metallic powder; combining at least the first metallic powder and the second metallic powder to provide a precursor powder comprising the large metal particles and the small metal particles; and subjecting the precursor powder to an impact blending process to adhere the small metal particles to the large particles, thereby producing a cold compactible metallic powder comprising non-spherical particles, wherein the non-spherical particles comprise one of the large metal particles as a core and a plurality of the small metal particles as protrusions from the core.
    Type: Application
    Filed: December 20, 2022
    Publication date: May 8, 2025
    Applicant: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
    Inventors: Robert Wilson, Shiqin Yan, Kun Yang, Ling Chen
  • Patent number: 12287081
    Abstract: A light fixture (50), comprising: an electronics housing (51); first and second heat sink structures (52, 54, 56, 58, 60, 62) coupled to the electronics housing, wherein each heat sink structure of the first and second heat sink structures is defined at least in part by a heat sink outer arc (64) having first and second end points (72, 74), and wherein each heat sink structure is further defined at least in part by two heat sink radii (66, 68) extending from the first and second end points, respectively, to a center point (P) of the light fixture; first and second light sources (53); at least two lenses (106, 108, 110, 112, 114, 116) comprising a first lens attached to the first heat sink structure and covering the first light source and a second lens attached to the second heat sink structure and covering the second light source, wherein each lens of the first and second lenses is defined at least in part by a lens outer arc (120) having first and second end points (128, 130), wherein each lens is further de
    Type: Grant
    Filed: April 11, 2022
    Date of Patent: April 29, 2025
    Assignee: SIGNIFY HOLDING B.V.
    Inventor: Ling Chen
  • Publication number: 20250122191
    Abstract: Provided are certain BCL-2 inhibitors, pharmaceutical compositions thereof, and methods of use thereof.
    Type: Application
    Filed: November 10, 2022
    Publication date: April 17, 2025
    Inventors: Hongbin LIU, Hua XU, Weipeng ZHANG, Rui TAN, Jinhua YU, Yunling WANG, Yangli QI, Yue RONG, Zhuo HUANG, Ling CHEN, Chenglin ZHOU, Lihua JIANG, Shu LIN, Xingdong ZHAO, Weibo WANG
  • Patent number: 12252942
    Abstract: A rolling and sliding adaptive device for guiding and fixing a drill pipe includes a mounting platform, where the mounting platform is provided with a through hole for the drill pipe to pass through. Multiple rolling and sliding support mechanisms are arranged around the through hole. The rolling and sliding support mechanisms each include a support seat. The support seat is provided with a contact element telescopic and swingable on the support seat. A telescopic drive mechanism is provided between the contact element and the support seat. The contact elements on the multiple rolling and sliding support mechanisms form a funnel-shaped structure with a large upper part and a small lower part around the through hole. The rolling and sliding adaptive device is used on a deep in-situ high-fidelity coring calibration platform for accurate positioning of an assembly process of a multi-section drill pipe bin.
    Type: Grant
    Filed: September 23, 2022
    Date of Patent: March 18, 2025
    Assignee: SICHUAN UNIVERSITY
    Inventors: Zetian Zhang, Heping Xie, Ru Zhang, Ling Chen, Yihang Li, Heng Gao, Jianan Li, Wei Huang, Li Ren, Kun Xiao, Weiqiang Ling, Chendi Lou
  • Patent number: D1095538
    Type: Grant
    Filed: August 29, 2024
    Date of Patent: September 30, 2025
    Inventor: Ling Chen
  • Patent number: D1110329
    Type: Grant
    Filed: May 7, 2024
    Date of Patent: January 27, 2026
    Inventor: Ling Chen
  • Patent number: D1112232
    Type: Grant
    Filed: August 23, 2024
    Date of Patent: February 10, 2026
    Assignee: Dongguan Yihe Silicone Rubber Technology Co., Ltd.
    Inventor: Ling Chen