Publication number: 20080124344
Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising disruptions in PRO226, PRO257, PRO268, PRO290, PRO36006, PRO363, PRO365, PRO382, PRO444, PRO705, PRO1071, PRO1125, PRO1134, PRO1155, PRO1281, PRO1343, PRO1379, PRO1380, PRO1387, PRO1419, PRO1433, PRO1474, PRO1550, PRO1571, PRO1572, PRO1759, PRO1904, PRO35193, PRO4341, PRO4348, PRO4369, PRO4381, PRO4407, PRO4425, PRO4985, PRO4989, PRO5737, PRO5800, PRO5993, PRO6017, PRO7174, PRO9744, PRO9821, PRO9852, PRO9873, PRO10196, PRO34778, PRO20233, PRO21956, PRO57290, PRO38465, PRO38683 or PRO85161 genes.
Type:
Application
Filed:
July 18, 2006
Publication date:
May 29, 2008
Applicant:
Genentech, Inc.
Inventors:
Katherin E. Combs, Ling Ling Culbertson, Juan Delmas-Mata, Frederic de Sauvage, Liangfen Fan, Gretchen Frantz, Leslie Jane Green, Erin Marie Massey, Dina Rebecca McLain, Charles Montgomery, Bobby Joe Payne, Franklin Peale, Heidi Phillips, Michelle Rohrer, Tracy E.W. Sevaux, Zheng-Zheng Shi, Mary Jean Sparks, Joy Anne Stala, Tracy Tzu-Ling Tang, Ching-Yun Wang, Wen Xiong, Peter Vogel