Patents by Inventor Ling Tong

Ling Tong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170165128
    Abstract: The present disclosure relates to wearable articles having an elastic belt having arrays of elastic bodies.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 15, 2017
    Inventors: Koichi MORIMOTO, Ling TONG, Chunmin CHENG
  • Publication number: 20170165127
    Abstract: Disclosed is a wearable article comprising a main body and a ring-like elastic belt comprising a front belt and a back belt. At least some of the elastic bodies may be arranged in at least 2 sets of a concentrated array defined as meeting: a) one concentrated array is formed by 2-4 elastic bodies; b) each elastic body within one concentrated array is disposed in an inner-interval between each elastic body of 2-4 mm; and c) one specific concentrated array disposed in an extra-interval between at least one neighboring elastic body outside the specific concentrated array of less than 8 mm. The entirety of the length of the belt side edge of the front belt may be seamed with a certain length of the belt side edge of the back belt to define a seam length LS. The front and back belts may each divided into 4 zones wherein at least 2 concentrated arrays are disposed on each of the front waist zone, the back waist zone, and the front leg zone.
    Type: Application
    Filed: February 27, 2017
    Publication date: June 15, 2017
    Inventors: Koichi MORIMOTO, Ling TONG, Chunmin CHENG
  • Publication number: 20170143560
    Abstract: Disclosed is a wearable article comprising a main body and a ring-like elastic belt comprising a front belt and a back belt. The entirety of the length of the belt side edge of the front belt may be seamed with a certain length of the belt side edge of the back belt to define a seam length LS. The front and back belts may each be divided into 4 zones extending in the transverse direction and defined by its location from the distal edge to the proximal edge relative to the percentage of the seam length LS where: 0-25% is the waist zone, 25-50% is the distal tummy zone, 50-85% is the proximal tummy zone, and 85-100% is the leg zone. The tensile stress of the front leg zone may be no more than 50% of the tensile stress of the front proximal tummy zone, and the tensile stress of the back leg zone may be no more than 100% of the tensile stress of the back proximal tummy zone.
    Type: Application
    Filed: February 3, 2017
    Publication date: May 25, 2017
    Inventors: Koichi MORIMOTO, Ling TONG, Chunmin CHENG
  • Patent number: 9555038
    Abstract: The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A?, R2 R3, R4 and R are as defined herein. The present invention also relates to compositions comprising at least one Heterocycle-Substituted Tetracyclic Compound, and methods of using the Heterocycle-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.
    Type: Grant
    Filed: December 31, 2013
    Date of Patent: January 31, 2017
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Wensheng Yu, Ling Tong, Joseph A. Kozlowski, Oleg Selyutin, Lei Chen, Jae-Hun Kim, Deyou Sha, Razia Rizvi, Bandarpalle Shankar
  • Publication number: 20160379053
    Abstract: A method and apparatus for identifying an object are disclosed. The method includes: performing linear feature detection on an image to be identified by using a linear feature detecting method to obtain detected linear features, wherein the linear feature detection method transforms detection of linear features in an image space to detection of extremal points in another space and assigns larger weights to continuous image points than to discrete image points during the transformation by using a continuous cluster factor; and identifying an object to be identified from the detected linear features by considering characteristics of the object to be identified. The method and apparatus for identifying an object of the invention, when used to detect and identify weak linear objects in high resolution remote sensing images, can effectively suppress the system noise and ambient noise, thereby successfully identifying the interested object and avoiding false alarms.
    Type: Application
    Filed: December 3, 2015
    Publication date: December 29, 2016
    Inventors: Yunping CHEN, Ling TONG, Weihong HAN
  • Patent number: 9527803
    Abstract: The present invention provides a new crystalline form VII of agomelatine, its method of preparation, application and pharmaceutical composition. This new crystalline form offers high purity, a stable crystalline structure and good reproducibility, while its method of production lends itself well to large scale production. In terms of stability and purity, it is superior to the numerous crystalline forms which have hitherto been reported. As a result, the crystalline form VII of the present invention possesses advantages in pharmaceutical preparation.
    Type: Grant
    Filed: March 22, 2012
    Date of Patent: December 27, 2016
    Assignees: LES LABORATOIRES SERVIER, SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY
    Inventors: Yu Huang, Ling Tong, Xueyan Zhu, Hanbin Shan, Zhedong Yuan, Xiong Yu
  • Publication number: 20160257697
    Abstract: Thiophene-substituted tetracyclic compounds of formula (I) and pharmaceutically acceptable salts thereof, wherein A, A?, R2, R3, R4 and R5 are as defined herein. The compositions comprising at least one thiophene-substituted tetracyclic compound, and methods of using the thiophene-substituted tetracyclic compounds for treating or preventing HCV infection in a patient are also provided.
    Type: Application
    Filed: December 31, 2013
    Publication date: September 8, 2016
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Ling Tong, Wensheng Yu, Joseph A. Kozlowski, Lei Chen, Oleg Selyutin, Seong Heon Kim, Michael Dwyer, Bin Hu, Bin Zhong, Dahai Wang, Jinglai Hao, Changmao Shen, Zhixin Lei, Weijun Wang
  • Patent number: 9433621
    Abstract: The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.
    Type: Grant
    Filed: February 18, 2011
    Date of Patent: September 6, 2016
    Assignees: Merck Sharp & Dohme Corp., Southern Research Institute
    Inventors: Ashok Arasappan, F. George Njoroge, Cecil D. Kwong, Subramaniam Ananthan, Frank Bennett, Francisco Velazquez, Vinay M. Girijavallabhan, Yuhua Huang, Hollis S. Kezar, III, Joseph A. Maddry, Robert C. Reynolds, Abhijit Roychowdhury, Anita T. Fowler, John A. Secrist, III, Joseph A. Kozlowski, Bandarpalle B. Shankar, Ling Tong, Seong Heon Kim, Malcolm MacCoss, Srikanth Venkatraman, Vishal Verma
  • Patent number: 9401008
    Abstract: A method for identifying and extracting a linear object from an image is disclosed. The method comprises: acquiring an original image to be processed, wherein the original image is taken by a camera, received through network transmission or copied from a compact disc or a removable disk; preprocessing the original image to obtain an enhanced image; extracting an edge information image from the enhanced image; then extracting linear features by performing, on the edge information image, a linear feature extracting transform improved with a cluster operator; finally; identifying and extracting the linear object by distinguishing the linear object from other linear features by considering characteristics of the linear object to be identified and extracted.
    Type: Grant
    Filed: January 16, 2015
    Date of Patent: July 26, 2016
    Assignee: UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY CHINA
    Inventors: Yunping Chen, Ling Tong, Yan Chen, Bo Gao, Yu Tian, Yuxia Li, Weihong Han, Yang Li
  • Publication number: 20160058628
    Abstract: A wearable article comprising: a main body comprising an outer cover layer and a backsheet attached to the skin-facing surface of the outer cover layer; and a ring-like elastic belt comprising a front belt and a back belt; the backsheet comprising a printed main artwork observable from the garment-facing side of the article. The main artwork exists in the vicinity of the proximal edge of the central panel of at least one of the front and back belts, extends from at least one of the front and back central panels into the crotch panel; and comprises a belt area artwork displayed on the central panel and a crotch area artwork displayed on the crotch panel. The relationship of the opacity of the outer cover layer to the opacity of the central panel overlayed on the garment facing side of the backsheet is defined herein.
    Type: Application
    Filed: August 26, 2015
    Publication date: March 3, 2016
    Inventors: Kouichi Morimoto, Ling Tong, Chunmin Cheng, Hui Liu
  • Patent number: 9233979
    Abstract: Disclosed are the ERK inhibitors of formula (1): and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1).
    Type: Grant
    Filed: September 26, 2013
    Date of Patent: January 12, 2016
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Kevin J. Wilson, David J. Witter, Phieng Siliphaivanh, Kathryn Lipford, David Sloman, Danielle Falcone, Brendan O'Boyle, Umar Faruk Mansoor, Jongwon Lim, Joey L. Methot, Christopher Boyce, Lei Chen, Matthew H. Daniels, Salem Fevrier, Xianhai Huang, Ravi Kurukulasuriya, Ling Tong, Wei Zhou, Joseph Kozlowski, Milana M. Maletic, Bidhan A. Shinkre, Jayanth Thiruvellore Thatai, Raman Kumar Bakshi, Ganesh Babu Karunakaran
  • Publication number: 20150335648
    Abstract: The present invention relates to novel Heterocycle-Substituted Tetracyclic Compounds of Formula (I): (I) and pharmaceutically acceptable salts thereof, wherein A, A?, R2 R3, R4 and R are as defined herein. The present invention also relates to compositions comprising at least one Heterocycle-Substituted Tetracyclic Compound, and methods of using the Heterocycle-Substituted Tetracyclic Compounds for treating or preventing HCV infection in a patient.
    Type: Application
    Filed: December 31, 2013
    Publication date: November 26, 2015
    Applicant: MERCK SHARP & DOHME CORP.
    Inventors: Wensheng Yu, Ling Tong, Joseph A. Kozlowski, Oleg Selyutin, Lei Chen, Jae-Hun Kim, Deyou Sha, Razia Rizvi, Bandarpalle Shankar, Bin Hu, Bin Zhong, Dahai Wang, Jinglai Hao, Wei Wei, Tao Ji, Shuai Zan
  • Publication number: 20150266895
    Abstract: Disclosed are the ERK inhibitors of formula (1): and the pharmaceutically acceptable salts thereof. Also disclosed are methods of treating cancer using the compounds of formula (1).
    Type: Application
    Filed: September 26, 2013
    Publication date: September 24, 2015
    Applicant: Merck Sharp & Dohme Corp.
    Inventors: Kevin J. Wilson, David J. Witter, Phieng Siliphaivanh, Kathryn Lipford, David Sloman, Danielle Falcone, Brendan O'Boyle, Umar Faruk Mansoor, Jongwon Lim, Joey L. Methot, Christopher Boyce, Lei Chen, Matthew H. Daniels, Salem Fevrier, Xianhai Huang, Ravi Kurukulasuriya, Ling Tong, Wei Zhou, Joseph Kozlowski, Milana M. Maletic, Bidhan A. Shinkre, Jayanth Thiruvellore Thatai, Raman Kumar Bakshi, Ganesh Babu Karunakaran
  • Publication number: 20150206025
    Abstract: A method for identifying and extracting a linear object from an image is disclosed. The method comprises: acquiring an original image to be processed, wherein the original image is taken by a camera, received through network transmission or copied from a compact disc or a removable disk; preprocessing the original image to obtain an enhanced image; extracting an edge information image from the enhanced image; then extracting linear features by performing, on the edge information image, a linear feature extracting transform improved with a cluster operator; finally; identifying and extracting the linear object by distinguishing the linear object from other linear features by considering characteristics of the linear object to be identified and extracted.
    Type: Application
    Filed: January 16, 2015
    Publication date: July 23, 2015
    Inventors: Yunping CHEN, Ling TONG, Yan CHEN, Bo GAO, Yu TIAN, Yuxia LI, Weihong HAN, Yang LI
  • Publication number: 20140378416
    Abstract: The present invention relates to novel Silyl-Containing Heterocyclic Compounds of Formula (I): and pharmaceutically acceptable salts thereof, wherein A, B, C, D, E, F and L are as defined herein. The present invention also relates to compositions comprising at least one Silyl-Containing Heterocyclic Compound, and methods of using the Silyl-Containing Heterocyclic Compounds for treating or preventing HCV infection in a patient.
    Type: Application
    Filed: September 11, 2012
    Publication date: December 25, 2014
    Inventors: Michael P. Dwyer, Kartik M. Keertikar, Qingbei Zeng, Robert D. Mazzola, JR., Wensheng Yu, Haiqun Tang, Seong Heon Kim, Ling Tong, Stuart B. Rosenblum, Joseph A. Kozlowski, Anilkumar Gopinadhan Nair
  • Patent number: 8859529
    Abstract: This invention relates to compounds of the Formula (I) as described herein, or a pharmaceutically acceptable salt, solvate or ester thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: October 14, 2014
    Assignee: Merck Sharp & Dohme Corp.
    Inventors: Bandarpalle B. Shankar, Seong Heon Kim, Wensheng Yu, Ling Tong, Michael K. C. Wong, Brian J. Lavey, Joseph A. Kozlowski, Lei Chen, Razia K. Rizvi, Aneta Maria Kosinski, De-Yi Yang, Guowei Zhou, Kristen E. Rosner, Luke Fire, Judson E. Richard, Dansu Li
  • Publication number: 20140242027
    Abstract: The present invention provides compounds of Formula (I): and tautomers, isomers, and esters of said compounds, and pharmaceutically acceptable salts, solvates, and prodrugs of said compounds, wherein each of R, R1, X, Y, Z, R2, R3, R4, R5, R6, R7, R8, R9, R18, R19 and n is selected independently and as defined herein. Compositions comprising such compounds are also provided. The compounds of the invention are effective as inhibitors of HCV, and are useful, alone and together with other therapeutic agents, in treating or preventing diseases or disorders such as viral infections and virus-related disorders.
    Type: Application
    Filed: February 18, 2011
    Publication date: August 28, 2014
    Applicants: Southern Research Institute, Merck Sharp & Dohne Corp.
    Inventors: Ashok Arasappan, F. George Njoroge, Cecil D. Kwong, Subramaniam Ananthan, Frank Bennett, Francisco Velazquez, Vinay Girijavallabhan, Yuhua Huang, Hollis S. Kezer, Joseph Maddry, Robert C. REynold, Abhijit Roychowdhury, Anita T. Fowler, John A. Secrist, III, Ling Tong, Seong Heon Kim, Malcolm MacCoss, Srikanth Venkatraman, vishal Verma
  • Patent number: 8772488
    Abstract: The present application discloses crystals of 2-acetoxy-5-(?-cyclopropylcarbonyl-2-fluorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine hydrobromate, crystal compositions and pharmaceutical compositions comprising them and their use. The crystals of prasugrel hydrobromate of the present application possess excellent stability and solubility.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: July 8, 2014
    Assignees: Shanghai Institute of Pharmaceutical Industry, Chia Tai Tianqing Pharmaceutical Group Co., Ltd
    Inventors: Zhedong Yuan, Xingdong Cheng, Yulei Yang, Ling Tong, Xiong Yu, Laifang Zhang, Wenliang Zhou
  • Publication number: 20140011883
    Abstract: The present invention provides a new crystalline form VII of agomelatine, its method of preparation, application and pharmaceutical composition. This new crystalline form offers high purity, a stable crystalline structure and good reproducibility, while its method of production lends itself well to large scale production. In terms of stability and purity, it is superior to the numerous crystalline forms which have hitherto been reported. As a result, the crystalline form VII of the present invention possesses advantages in pharmaceutical preparation.
    Type: Application
    Filed: March 22, 2012
    Publication date: January 9, 2014
    Applicants: SHANGHAI INSTITUTE OF PHARMACEUTICAL INDUSTRY, LES LABORATOIRES SERVIER
    Inventors: Yu Huang, Ling Tong, Xueyan Zhu, Hanbin Shan, Zhedong Yuan, Xiong Yu
  • Patent number: D782663
    Type: Grant
    Filed: August 27, 2014
    Date of Patent: March 28, 2017
    Assignee: The Procter and Gamble Company
    Inventors: Koichi Morimoto, Ling Tong, Li Yu, Chunmin Cheng