Patents by Inventor Ling Tong

Ling Tong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20090156586
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-? or combinations thereof.
    Type: Application
    Filed: February 3, 2009
    Publication date: June 18, 2009
    Inventors: Brian J. Lavey, Joseph A. Kozlowski, Guowei Zhou, Ling Tong, Wensheng Yu, Michael K. C. Wong, Bandarpalle B. Shankar, Neng-Yang Shih, M. Arshad Siddiqui, Kristin E. Rosner, Chaoyang Dai, Janeta Popovici-Muller, Vinay M. Girijavallabhan, Dansu Li, Razia Rizvi, Lei Chen, De-Yi Yang, Robert Feltz, Seong Heon Kim
  • COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20090137586
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
    Type: Application
    Filed: December 18, 2008
    Publication date: May 28, 2009
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph A. Kozlowski, Brian J. Lavey, Neng-Yang Shih, Vincent S. Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael K.C. Wong, De-Yi Yang, Seong Heon Kim, Bandarpalle B. Shankar, M. Arshad Siddiqui, Kristin E. Rosner, Chaoyang Dai, Janeta Popovici-Muller, Vinay M. Girijavallabhan, Dansu Li, Razia Rizvi, Aneta M. Micula, Robert Feltz
  • COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20090111803
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, TNF—or combinations thereof.
    Type: Application
    Filed: December 18, 2008
    Publication date: April 30, 2009
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph A. Kozlowski, Brian J. Lavey, Neng-Yang Shih, Vincent S. Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael K.C. Wong, De-Yi Yang, Seong Heon Kim, Bandarpalle B. Shankat
  • Compounds for the treatment of inflammatory disorders
    Patent number: 7524842
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-? or combinations thereof.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: April 28, 2009
    Assignee: Schering Corporation
    Inventors: Brian J. Lavey, Joseph A. Kozlowski, Guowei Zhou, Ling Tong, Wensheng Yu, Michael K. C. Wong, Bandarpalle B. Shankar, Neng-Yang Shih, M. Arshad Siddiqui, Kristin E. Rosner, Chaoyang Dai, Janeta Popovici-Muller, Vinay M. Girijavallabhan, Dansu Li, Razia Rizvi, Lei Chen, De-Yi Yang, Robert Feltz, Seong Heon Kim
  • Cannabinoid receptor ligands
    Patent number: 7507767
    Abstract: There are disclosed compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds and methods of using the compounds for the treatment of various diseases and conditions.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: March 24, 2009
    Assignee: Schering Corporation
    Inventors: Joseph A. Kozlowski, Neng-Yang Shih, Brian J. Lavey, Razia K. Rizvi, Bandarpalle B. Shankar, James M. Spitler, Ling Tong, Ronald L. Wolin, Michael K. Wong
  • Compounds for the treatment of inflammatory disorders
    Patent number: 7504424
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
    Type: Grant
    Filed: January 17, 2006
    Date of Patent: March 17, 2009
    Assignee: Schering Corporation
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph A. Kozlowski, Brian J. Lavey, Neng-Yang Shih, Vincent S. Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael K. C. Wong, De-Yi Yang, Seong Heon Kim, Bandarpalle B. Shankar, M. Arshad Siddiqui, Kristin E. Rosner, Chaoyang Dai, Umar Faruk Mansoor, Janeta Popovici-Muller, Vinay M. Girijavallabhan, Dansu Li
  • Compounds for the treatment of inflammatory disorders
    Patent number: 7488745
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
    Type: Grant
    Filed: January 16, 2007
    Date of Patent: February 10, 2009
    Assignee: Schering Corporation
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph A. Kozlowski, Brian J. Lavey, Neng-Yang Shih, Vincent S. Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael K. C. Wong, De-Yi Yang, Seong Heon Kim, Bandarpalle B. Shankar, M. Arshad Siddiqui, Kristin E. Rosner, Chaoyang Dai, Janeta Popovici-Muller, Vinay M. Girijavallabhan, Dansu Li, Razia Rizvi, Aneta M. Micula, Robert Feltz
  • Compounds for the treatment of inflammatory disorders
    Patent number: 7482370
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, TNF- or combinations thereof.
    Type: Grant
    Filed: July 13, 2005
    Date of Patent: January 27, 2009
    Assignee: Schering Corporation
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph A. Kozlowski, Brian J. Lavey, Neng-Yang Shih, Vincent S. Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael K. C. Wong, De-Yi Yang, Seong Heon Kim, Bandarpalle B. Shankar
  • Compounds for the treatment of inflammatory disorders
    Publication number: 20070265299
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPS, ADAMs, TACE, aggrecanase, TNF-? or combinations thereof.
    Type: Application
    Filed: January 16, 2007
    Publication date: November 15, 2007
    Inventors: Brian Lavey, Joseph Kozlowski, Guowei Zhou, Ling Tong, Wensheng Yu, Michael Wong, Bandarpalle Shankar, Neng-Yang Shih, M. Siddiqui, Kristin Rosner, Chaoyang Dai, Janeta Popovici-Muller, Vinay Girijavallabhan, Dansu Li, Aneta Micula, Seong-Heon Kim, De-Yi Yang, Razia Rizvi
  • Compounds for the treatment of inflammatory disorders
    Publication number: 20070219218
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
    Type: Application
    Filed: January 16, 2007
    Publication date: September 20, 2007
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph Kozlowski, Brian Lavey, Neng-Yang Shih, Vincent Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael Wong, De-Yi Yang, Seong Kim, Bandarpalle Shankar, M. Siddiqui, Kristin Rosner, Chaoyang Dai, Janeta Popovici-Muller, Vinay Girijavallabhan, Dansu Li, Razia Rizvi, Aneta Micula, Robert Feltz
  • Compounds for the treatment of inflammatory disorders
    Publication number: 20070197564
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF-? or combinations thereof.
    Type: Application
    Filed: January 16, 2007
    Publication date: August 23, 2007
    Inventors: Brian Lavey, Joseph Kozlowski, Guowei Zhou, Ling Tong, Wensheng Yu, Michael Wong, Bandarpalle Shankar, Neng-Yang Shih, M. Siddiqui, Kristin Rosner, Chaoyang Dai, Janeta Popovici-Muller, Vinay Girijavallabhan, Dansu Li, Razia Rizvi, Lei Chen, De-Yi Yang, Robert Feltz, Seong-Heon Kim
  • Cannabinoid receptor ligands
    Patent number: 7253189
    Abstract: A compound of the formula or a pharmaceutically acceptable salt or solvate thereof, wherein: R1, R2, L1, L2, M1, M2, n, p, q, A, D, X, Y and Z are as described in the specification; pharmaceutical compositions thereof, methods of making said pharmaceutical compositions; and methods of use thereof.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: August 7, 2007
    Assignee: Schering Corporation
    Inventors: Ling Tong, Lei Chen, Bandarpalle B. Shankar, Joseph A. Kozlowski, Neng-Yang Shih
  • Cannabinoid receptor agonists
    Patent number: 7217732
    Abstract: A compound of the formula or a pharmaceutically acceptable salt thereof, wherein: R1, R2, R3, R4, R5, R6, L1, L2, M, n, p, X, Y and Z are as described in the specification; pharmaceutical compositions thereof, methods of making said pharmaceutical compositions; and methods of use thereof.
    Type: Grant
    Filed: June 17, 2003
    Date of Patent: May 15, 2007
    Assignee: Schering Corporation
    Inventors: Joseph A. Kozlowski, Bandarpalle B. Shankar, Neng-Yang Shih, Ling Tong
  • Compounds for the treatment of inflammatory disorders
    Publication number: 20060276506
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, aggrecanase, TNF- or combinations thereof.
    Type: Application
    Filed: January 17, 2006
    Publication date: December 7, 2006
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph Kozlowski, Brian Lavey, Neng-Yang Shih, Vincent Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael Wong, De-Yi Yang, Seong Kim, Bandarpalle Shankar, M. Siddiqui, Kristin Rosner, Chaoyang Dai, Umar Mansoor, Janeta Popovici-Muller, Vinay Girijavallabhan, Dansu Li
  • Compounds for the treatment of inflammatory disorders
    Publication number: 20060205797
    Abstract: This invention relates to compounds of the Formula (I): or a pharmaceutically acceptable salt, solvate or isomer thereof, which can be useful for the treatment of diseases or conditions mediated by MMPs, ADAMs, TACE, TNF—combinations thereof.
    Type: Application
    Filed: July 13, 2005
    Publication date: September 14, 2006
    Inventors: Wensheng Yu, Ling Tong, Lei Chen, Joseph Kozlowski, Brian Lavey, Neng-Yang Shih, Vincent Madison, Guowei Zhou, Peter Orth, Zhuyan Guo, Michael Wong, De-Yi Yang, Seong Kim, Bandarpalle Shankar
  • Cannabinoid receptor ligands
    Patent number: 7071213
    Abstract: There are disclosed compounds of the formula I: or a pharmaceutically acceptable salt of the compound, which exhibit anti-inflammatory and immunomodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: July 4, 2006
    Assignee: Schering Corporation
    Inventors: Richard J. Friary, Joseph A. Kozlowski, Bandarpalle B. Shankar, Michael K. C. Wong, Guowei Zhou, Brian J. Lavey, Neng-Yang Shih, Ling Tong, Lei Chen, Youheng Shu
  • Cannabinoid receptor ligands
    Patent number: 7067539
    Abstract: The invention relates to compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds and methods of using the compounds for the treatment of various diseases and conditions.
    Type: Grant
    Filed: August 7, 2002
    Date of Patent: June 27, 2006
    Assignee: Schering Corporation
    Inventors: Joseph A. Kozlowski, Neng-Yang Shih, Brian J. Lavey, Razia K. Rizvi, Bandarpalle B. Shankar, James M. Spitler, Ling Tong, Ronald L. Wolin, Michael K. Wong
  • Cannabinoid receptor ligands
    Publication number: 20060009528
    Abstract: There are disclosed compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds and methods of using the compounds for the treatment of various diseases and conditions.
    Type: Application
    Filed: August 15, 2005
    Publication date: January 12, 2006
    Inventors: Joseph Kozlowski, Neng-Yang Shih, Brian Lavey, Razia Rizvi, Bandarpalle Shankar, James Spitler, Ling Tong, Ronald Wolin, Michael Wong
  • Cannabinoid receptor ligands
    Publication number: 20050282861
    Abstract: There are disclosed compounds of the formula I: or a pharmaceutically acceptable salt of the compound, which exhibit anti-inflammatory and immunomodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds.
    Type: Application
    Filed: August 5, 2005
    Publication date: December 22, 2005
    Inventors: Richard Friary, Joseph Kozlowski, Bandarpalle Shankar, Michael Wong, Guowei Zhou, Brian Lavey, Neng-Yang Shih, Ling Tong, Lei Chen, Youhen Shu
  • Process for homogenizing polyolefin drag reducing agents
    Patent number: 6894088
    Abstract: A process for producing polymer drag reducing agent (DRA) slurries without cryogenic temperatures or conventional grinding is described. The homogenizing or size reduction of polymer, such as poly(alpha-olefins), may be achieved by the use of granulated polymer and at least one liquid, non-solvent for the polymer DRA. In one non-limiting embodiment of the invention, the homogenizing is conducted at ambient temperature. Examples of suitable non-solvents include water and non-aqueous non-solvents including, but not necessarily limited to, alcohols, glycols, glycol ethers, ketones, and esters; having from 2-6 carbon atoms, and combinations thereof. The polymeric DRA may be homogenized to an average particle size of about 600 microns or less.
    Type: Grant
    Filed: March 24, 2003
    Date of Patent: May 17, 2005
    Assignee: Baker Hughes Incorporated
    Inventors: John F. Motier, Lo-Chien Chou, Chee Ling Tong