Abstract: A pixel circuit includes a data writing sub-circuit inputs a signal input via a second signal terminal to a compensating sub-circuit and a driving sub-circuit under control of a signal from a first signal terminal, the compensating sub-circuit compensates a threshold voltage of the driving sub-circuit according to a signal output from the data writing sub-circuit under control of a signal from a third signal terminal, a light-emitting control sub-circuit inputs a signal from a first voltage terminal to the driving sub-circuit and the compensating sub-circuit under control of a signal from a fourth signal terminal, the driving sub-circuit configured to generate and input a driving current to a light-emitting sub-circuit according to a signal output from the light-emitting control sub-circuit and a signal output from the data writing sub-circuit, and the light-emitting sub-circuit configured to emit light according to the driving current under control of a second voltage terminal.

Abstract: The present disclosure provides peptides comprising a motif having four amino acids, wherein each of the amino acids at N-terminus and C-terminus of the sequence independently has a same or different positively charged side chain, and each of the amino acids between the N-terminal and C-terminal of the motif independently has a same or different uncharged side chain. The present disclosure surprisingly found that these peptides have advantageous effects in inhibiting or decreasing collagen breakdown, increasing production of collagen, elastin and/or hyaluronic acid, retarding aging, improving skin and inhibiting inflammation.

Abstract: A display panel, a display device and a compensation method are provided. The display panel includes at least one pixel unit group, at least one sensing line, a plurality of gate lines, a plurality of first data lines and a plurality of second data lines. Each pixel unit group includes a plurality of pixel units arranged in two rows and a plurality of columns, the plurality of pixel units in each pixel unit group are connected to a same one of the gate lines, one of two pixel units in each column of each pixel unit group is connected to one of the first data lines corresponding thereto, other one is connected to one of the second data lines corresponding thereto, the plurality of pixel units in each pixel unit group are connected to a same sensing line.

Abstract: Disclosed are a display panel and a display device. The display panel includes a base substrate; a plurality of data signal lines on the base substrate, and a plurality of pixel units; and each pixel unit has a transparent area and a non-transparent area; the pixel unit includes a plurality of sub-pixels in the non-transparent area.

Abstract: Disclosed are a pixel array substrate and a driving method thereof, a display panel, and a display device. The pixel array substrate includes a plurality of pixel units arranged in a plurality of pixel rows, and common electrodes distributed in the plurality of pixel rows. Each of the plurality of pixel units includes a light emitting element, first electrodes of light emitting elements of a plurality of pixel units in each of the plurality of pixel rows are electrically connected with each other to form a common electrode in the each of the plurality of pixel rows, and the common electrodes in the plurality of pixel rows are insulated from each other.

Abstract: A method for repairing a display substrate includes detecting whether there is a fault point on signal lines. If a fault point is detected on a signal line, short-circuiting is performed of two sides of the at least one fault point through line portions of two drive power lines respectively located at two sides of the at least one fault point and perpendicular to the signal line where the at least one fault point is located and a line portion of a drive power line located at one side of the at least one fault point and parallel to the signal line where the at least one fault point is located.

Abstract: The disclosure relates to a data transmission interface for use in a first integrated circuit (IC) for encoding and sending a data packet from the first IC to a second IC via a data bus having four data wires, the data transmission interface arranged to generate four time-dependent binary signals which jointly encode the data packet in signal edges thereof, each of the signals being associated with a unique wire of the data bus and spanning a temporal cycle T within which are defined four consecutive time stamps T1 . . . T4 at which edges can occur in the signals, the data transmission interface further arranged to transmit the signals to the second IC substantially in parallel on their respective data wires, wherein: irrespective of the data packet content, at each time stamp T1 . . . T4 at least one of the four signals has an edge to enable clock recovery at the second IC.

Abstract: The present disclosure provides a display substrate, including: a base substrate, which includes a display region and a driving region arranged on at least one side of the display region; a first electrode layer disposed in the display region; a signal output part disposed in the driving region, the first electrode layer is electrically coupled to the signal output part, the first electrode layer comprises a plurality of electrode regions each having a same area; and a plurality of auxiliary electrodes, which are in one-to-one correspondence with the plurality of electrode regions and configured to be coupled in parallel with the first electrode layer, a resistance of each auxiliary electrode is inversely correlated with a minimum distance from the electrode region corresponding to said each auxiliary electrode to the signal output part. The present disclosure further provides a display panel and a manufacturing method thereof and a display device.

Abstract: This invention presents a solar light collecting and guiding system for stabilizing the output light intensity, wherein the system comprising an array of converging lenses and optical fibers for collecting light focused by converging lenses. The fibers and the lenses are in one-to-one correspondence wherein the input end of an optical fiber is located in the focus position of the corresponding converging lens, and the axis of the optical fiber overlaps with the principal axis of the corresponding converging lens. The system is equipped with a sunlight tracking positioning device for synchronized motion, wherein the device is applied to tracking the sun light ray vertical incident into the central converging lens. The system has the function of outputting stable light intensity, that is, it can effectively reduce the variation of the collecting efficiency caused by the positioning deviation between the incident angle of sunlight and the designed input angle.

Abstract: The present disclosure provides peptides comprising a motif having four amino acids, wherein each of the amino acids at N-terminus and C-terminus of the sequence independently has a same or different positively charged side chain, and each of the amino acids between the N-terminal and C-terminal of the motif independently has a same or different uncharged side chain. The present disclosure surprisingly found that these peptides have advantageous effects in inhibiting or decreasing collagen breakdown, increasing production of collagen, elastin and/or hyaluronic acid, retarding aging, improving skin and inhibiting inflammation.

Abstract: This disclosure is directed to methods, compounds and compositions for delivering nucleic acids to a cell of interest. In particular, it provides salts that are particularly effective in delivering nucleic acids to cells in the lung for disorders such as cystic fibrosis (CF).

Abstract: The present invention relates to a bifunctional angiogenesis inhibitor, which has VEGF inhibitory activity and FGF inhibitory activity, and can inhibit VEGF and FGF dual factors-induced or high glucose-induced cell proliferation, cell migration, and/or lumen formation. The present invention also relates to the use of the bifunctional angiogenesis inhibitor in inhibiting retinal angiogenesis, such as diabetic retinopathy, age-related macular degeneration and the like.

Abstract: The present invention relates to anti-IL-23p19 binding compounds, in particular new humanized anti-IL-23p19 antibodies, pharmaceutical compositions and therapeutic and diagnostic methods and compositions for using the same.

Abstract: An OLED display substrate, a manufacturing method thereof, and a display device are provided. The manufacturing method includes forming a PIN photodiode on a base substrate, forming an insulative protection layer covering the PIN photodiode, and forming an oxide TFT. The PIN photodiode is formed prior to the formation of an active layer of the oxide TFT, and the insulative protection layer covering the PIN photodiode is formed prior to the formation of a source electrode and a drain electrode of the oxide TFT.

Abstract: A thin film transistor includes: a substrate base; a first gate electrode at a side of the substrate base; an active layer at a side of the first gate electrode away from the substrate base; a second gate electrode at a side of the active layer away from the substrate base; and a source/drain electrode at a side of the second gate electrode away from the substrate base. An orthographic projection of the source/drain electrode on the substrate base is at least partially overlapped with an orthographic projection of the second gate electrode on the substrate base.

Abstract: A pixel circuit includes a first transistor having a bottom gate and a top gate, a drain supplied with a high-level power-supply voltage, and a source coupled to a light-emitting diode (LED). The bottom gate is provided with a first voltage signal and the source is provided with a second voltage signal in a compensation period during which a present value of a threshold voltage of the first transistor is sensed at the source and a third voltage signal is determined based on the present value of the threshold voltage. The top gate is configured to be provided with the third voltage signal in an emission period to reduce the present value of the threshold voltage.

Abstract: Provided are a display substrate, a manufacturing method thereof and a display device. The display substrate includes a base and a plurality of subpixels arranged on the base in an array form. Each subpixel includes a light-emitting element, a subpixel driving circuitry coupled to the light-emitting element, and a light-emission detection circuitry configured to detect luminescence of light emitted by the light-emitting element. The light-emission detection circuitry includes a first control transistor and a PIN-type photodiode laminated in that order in a direction away from the base, a first electrode of the first control transistor is coupled to a cathode of the PIN-type photodiode, and an orthogonal projection of the first control transistor onto the base at least partially overlaps an orthogonal projection of the PIN-type photodiode onto the base.

Abstract: Provided herein are KRAS G12C inhibitors, composition of the same, and methods of using the same. These inhibitors are useful for treating a number of disorders, including pancreatic, colorectal, and lung cancers.

Abstract: The present invention relates to anti-IL-23p19 binding compounds, in particular new humanized anti-IL-23p19 antibodies, pharmaceutical compositions and therapeutic and diagnostic methods and compositions for using the same.

Abstract: The embodiment of the present disclosure discloses an array substrate, a fabrication method thereof, and a display device. The array substrate includes: a base substrate and a plurality of pixel units on the base substrate, wherein the pixel unit includes a plurality of sub-pixels; and the sub-pixel includes an electroluminescent component, a pixel circuit and a photo detection circuit; the pixel circuit includes a drive transistor for driving the electroluminescent component to emit light, and the drive transistor is a low temperature poly-si thin film transistor; and the photo detection circuit includes a detection switch transistor and a PIN-type photodiode, and the detection switch transistor is a metal oxide transistor.