Abstract: Disclosed are compositions and methods for treating or preventing the formation of drusen in a patient in need thereof. The compositions include an effective amount of at least one polypeptide present in drusen, or an immunogenic fragment or variant thereof that induces an immune response against the polypeptide, together with a pharmaceutical carrier, excipient, or diluent. The compositions are suitable as vaccines for treating or preventing drusen and diseases associated with drusen.

Abstract: A driving method of pixels of a display panel is provided, which is adapted to drive a pixel of the display panel corresponding to a target grey-level of a display frame. In this method, a first pixel voltage is applied to the pixel during a first display period. At least one second pixel voltage is applied to the pixel during a second display period. The first and second display periods correspond to the display frame, and an enabling duration of the second display period is longer than the enabling duration of the first display period. When the target grey-level is not equal to a limit grey-level, the grey-level corresponding to the pixel voltage is different from the grey-level corresponding to the second pixel voltages. A sum of optical effects of the pixel during the first and second display periods is equal to the optical effect of the target grey-level.

Abstract: The present invention relates to novel synthetic substituted heterocyclic compounds and pharmaceutical compositions containing the same that are capable of inhibiting or antagonizing a family of receptor tyrosine kinases, Tropomysosin Related Kinases (Trk), in particular the nerve growth factor (NGF) receptor, TrkA. The invention further concerns the use of such compounds in the treatment and/or prevention of pain, cancer, restenosis, atherosclerosis, psoriasis, thrombosis, or a disease, disorder or injury relating to dysmyelination or demyelination or the disease or disorder associated with abnormal activities of NGF receptor TrkA.

Abstract: An LED light string includes a socket, electrical wires, and an LED-based luminous element. The LED luminous element has two conductive terminals respectively set in abutting contact with or to pierce through the electrical wires. The socket is composed of two unsymmetrical casing members. The electrical wires and the luminous element are first placed in the first casing member and then, the second casing member is fit to and attached to the first casing member. Ultrasonic wave is then applied to achieve secure coupling of the light string.

Abstract: A method for manufacturing a light guide apparatus includes the following steps. A first mold and a second mold are provided. The first mold and the second mold respectively include a first molding surface and a second molding surface facing each other. A protrusion is disposed at the first or second molding surfaces. Sheet materials are provided. Each sheet material includes an opening corresponding to the protrusion, a first surface and a circuit layer disposed on the first surface. One of the sheet materials is disposed on the first mold with first surface facing the first mold. The first mold and the second mold are closed. An optical plastic material is injected into the space between the first and second molding surfaces to form a light guide plate having a via corresponding to the protrusion for embedding a light source. The sheet material is laminated on the light guide plate.

Abstract: Terminal devices and methods for designing a network application product are provided. The terminal device includes a task starting interface, a graphical displaying interface, an inputting interface. The task starting interface is configured to receive a task starting instruction to obtain a plurality of first type e-cards having at least one dimensionality type. Each first type e-card contains graphic information corresponding to a dimensionality type and text information corresponding to the graphic information. The graphical displaying interface is configured to display the plurality of first type e-cards. The inputting interface is configured to receive an inputting instruction to select at least two first type e-cards from the plurality of first type e-cards. The inputting interface is further configured to receive context information generated by correlating information including the graphic information and the text information on the at least two first type e-cards.

Abstract: A tunnel magnetoresistance (TMR) read sensor having a tabbed AFM layer and an extended pinned layer and methods for making the same are provided. The TMR read sensor has an AFM layer recessed from the air bearing surface, providing a reduced shield-to-shield distance.

Abstract: System and methods are provided for the manufacture of a magnetic write head including a pole and yoke region, and a nose shape transition region connecting the yoke to the pole having very small minimum radius of curvature, providing for a sharp transition. A double mask technique is used providing for the adjustment of an offset and illumination conditions between the first and second mask, which provides the capability of tuning the shape of the transition region, and achieving features that would otherwise not be achievable due to distortions caused by optical proximity effect.

Abstract: The invention relates to various polymorphic forms and amorphous form of sodium 4-((3-(4-cyclohexylpiperazin-1-yl)-6-oxo-6H-anthra[1,9-cd]isoxazol-5-yl)amino)benzate, including the polymorphic form A, mixtures of the polymorphs, process for the preparation thereof and the use thereof in a pharmaceutical composition containing thereof.

Abstract: The present invention relates to a method for synthesizing water-soluble particles, the method includes providing a solution including a lanthanide compound, a halide compound, and a first solvent; introducing a capping agent into the solution to form a mixture; heating the mixture under pressure to produce the particles; and recovering the particles from the mixture. The present invention also relates to a water-soluble particle having a surface functional group. The particles exhibit up-conversion luminescence utilizing NIR excitation, wherein the particles are synthesized in a one-pot process.

Abstract: Innovative techniques are disclosed for fabricating microelectronic devices using an alternating phase shift mask. Some embodiments of the invention encompass a double exposure technique that utilize high resolution line patterning such that two opaque lines intersect at an angle. After development, substantially circular images may be formed. In certain embodiments, high resolution disk imaging as small as 60 nm is possible.

Abstract: A folding ball trolley has a frame and a bag. The frame has two main rod assemblies and two connecting rod assemblies. When the folding ball trolley is expanded, the main rods and the connecting rods lean outward under gravity until the main rods brace the bag. The bag holds the main rods at a specific angle, and the main rods hold the connecting rods at a specific angle. The main rod assemblies and the connecting rod assemblies are connected into a rectangle, such that the frame is expanded horizontally when the rods are leant outward. Thus, the folding ball trolley can achieve auto expansion without any resilient element, and therefore a user does not have to resist the resilient force when folding. Besides, the amount of the rods is reduced to eight (four main rods and four connecting rods), which reduces the manufacturing cost and facilitates ease of assembly.

Abstract: An approach is provided distributing content to multiple devices. Specifically, a distribution module causes, at least in part, a rendering of at least one user interface for distributing content among at least one device and one or more other devices with connectivity to the at least one device. The distribution module then causes, at least in part, one or more segmentations of the at least one user interface, wherein the one or more segmentations are associated with the at least one device, respective one or more of the one or more other devices, or a combination thereof. Next, the distribution module determines one or more interactions with the at least one user interface, the one or more segmentations, or a combination thereof to cause, at least in part, a distribution of the content.

Abstract: An optical image stabilizer includes a magnetic element, a moving platform, at least one first sensor and at least one second sensor. The magnetic element is fixed on a main body. The moving platform is movably disposed on the main body. The first and the second sensors are fixed on the moving platform. When the moving platform moves relatively to the main body, the first sensor senses a variation of a magnetic force applied to the first sensor by the magnetic element for calculating a displacement of the moving platform along a first direction, and the second sensor senses a variation of a magnetic force applied to the second sensor by the magnetic element for calculating a displacement of the moving platform along a second direction. The first direction is perpendicular to the second direction. In addition, an image capturing device having the optical image stabilizer is also provided.

Abstract: A digital decoder, used in a reconfigurable circuit, for decoding digital pulses includes a phase indicator module having inputs coupled to a reference pulse input and a data pulse input. The phase indicator module has timing information outputs that provide logic values indicative of rising and falling edges of pulses occurring on the reference pulse input and the data pulse input. A phase decoder module has inputs coupled to the timing information outputs, and outputs decoded binary data values. In operation, the phase decoder module compares at least two of the logic values at the timing information outputs with a signal representative leading and trailing edges of a pulse applied to one of the phase inputs to determine a pulse arrival order sequence on the phase inputs and thereby provide the decoded binary data values.

Abstract: A golf putter grip comprises a main tubular body having a non-circular cross-section being symmetrical and remaining similar throughout its axial length, and a flat front area also along and throughout its axial length. The non-circular cross-section and the flat front area respectively have a width dimension sufficient to have two hands cupped together at the same height and two thumbs placed side by side on the flat front area to hold the putter grip comfortably with minimal wrist breaking-down. The main tubular body has flat-topped arch cross-section and is reversely tapered, and its reverse taper is sufficient in certain degrees to accommodate different finger lengths of two hands for reducing the gripping pressure, so as to make the gripping comfortable.

Abstract: In certain embodiments of the invention, a serializer has a transfer stage that transfers N-bit parallel data from a relatively slow timing domain to a relatively fast timing domain and a serializing stage that converts the parallel data into serialized data. Between the transfer stage and the serializing stage is an update stage that buffers the data and can be used to toggle the serializer between an N?1 operating mode and an N+1 operating mode.

Abstract: A method and an information inquiring apparatus is provided. The method includes: acquiring facial image of a target user to be inquired when receiving query information request; querying social network service information of the target user matching with the facial image, based on the facial image of the target user; and outputting social network service information of the target user. The method and the information inquiring apparatus are configured to increase efficiency of information queries and improve intelligence of the SNS application.

Abstract: A socket is provided for an LED light string and is formed by jointing two unsymmetrical casing members through thermal fusion by application of ultrasonic wave to thereby securely combine with electrical wires and a luminous element. The first and second casing members are provided with raised-and-recessed inter-engageable structures including holes and protrusions and multiple tiny bosses that is thermally fusible through application of ultrasonic wave for adhesion purposes. The first casing member includes a receiving channel for receiving electrical wires therein and the second casing member includes hold-down blocks and holding blocks for holding the electrical wires in position.

Abstract: An LED light string includes a socket, electrical wires, and an LED-based luminous element. The LED luminous element has two conductive terminals respectively set in abutting contact with or to pierce through the electrical wires. The socket is composed of two unsymmetrical casing members. The electrical wires and the luminous element are first placed in the first casing member and then, the second casing member is fit to and attached to the first casing member. Ultrasonic wave is then applied to achieve secure coupling of the light string.