Abstract: The present invention relates to a novel RNA picornavirus that is called Seneca Valley virus (“SVV”). The invention provides isolated SVV nucleic acids and proteins encoded by these nucleic acids. Further, the invention provides antibodies that are raised against the SVV proteins. Because SVV has the ability to selectively kill some types of tumors, the invention provides methods of using SVV and SVV polypeptides to treat cancer. Because SVV specifically targets certain tumors, the invention provides methods of using SVV nucleic acids and proteins to detect cancer. Additionally, due to the information provided by the tumor-specific mechanisms of SVV, the invention provides methods of making new oncolytic virus derivatives and of altering viruses to have tumor-specific tropisms.

Abstract: A connector plug arrangement (330, 600, 700) includes a connector body (334, 610, 720); and an indication component (335, 650, 750). The indication component (335, 650, 750) includes a first portion (337, 653, 751) that is disposed at a rear end of the connector body and a second portion (339, 654, 753) that extends outwardly from the first portion (337, 653, 751). The first portion (337, 653, 751) is configured to extend along a circumferential perimeter of the connector body (334, 610, 720). The second portion (339, 654, 753) is configured to extend along the longitudinal axis of the connector body (334, 610, 720).

Abstract: The disclosure provides a method and a system for processing an authenticator relocation request. When detecting that initial authentication, re-authentication or authenticator relocation is being performed for a terminal, a network side refuses a new authenticator relocation request from the terminal. When detecting that no initial authentication, re-authentication or authenticator relocation is being performed for the terminal, the network side accepts the new authenticator relocation request from the terminal. Further, when detecting that the initial authentication, the re-authentication or the authenticator relocation is being performed for the terminal, the network side refuses a new re-authentication request from the terminal. According to the technical solution of the disclosure, the complexity of network element processing is reduced and potential safety hazard is avoided.

Abstract: Isolated immunogens including a HIV-1 gp120 polypeptide or immunogenic fragment thereof stabilized in a CD4 bound confirmation by crosslinked cysteines, and methods of their use are disclosed. The immunogens are useful, for example, for generating an immune response to HIV-1 gp120 in a subject.

Abstract: A method for updating a connection relationship of a wireless relay station, comprises the following steps of: (a) a wireless relay station RS1 already connecting to a wireless communication network group comprising a base station and wireless relay stations subjected to the base station, and if determining that the connection relationship of RS1 needs to be changed, selecting a target node; (b) instructing RS1 to update the connection to the target node, and after receiving the instructions, RS1 starting a connection update, establishing a wireless link to a new node and releasing no longer used resource in an existing data tunnel. The present invention can fulfill the update of the connection relationship of a wireless relay station, and can take steps to further guarantee the service suspension time of the terminals and RSs subjected to the wireless relay station is the shortest.

Abstract: The present invention discloses a method for scheduling wireless resources of a multi-base station MBS and a method for sending occupation information. The scheduling method comprises: dividing wireless resources of downlink sub-frames of all base stations in an MBS Zone into two parts, local service schedulers on the base stations scheduling one part for local services, and a multi-base station MBS resource scheduler in the MBS Zone scheduling the other part for the multi-base station MBS. The sending method comprises: a sender informing a receiver of multi-base station MBS wireless resource occupation situation through a message carrying multi-base station MBS wireless resource occupation information; the occupation information including configuration information and a scheduling result. When supporting the macro diversity multi-base station MBS, the present invention not only can avoid the conflict of unicast and MBS scheduling, but also can fully utilize the limited wireless resources of the system.

Abstract: Wireless communication relay networks and techniques for providing data synchronization in Multicast Broadcast Services (MBS).

Abstract: A method for entering an idle mode, which is used in a Worldwide Interoperability for Microwave Access system, comprising: during the procedure of a terminal enter to idle mode from active mode, an paging agent of the terminal sending mobility restriction parameters of the terminal to a mobility restriction parameter storage network element; the mobility restriction parameter storage network element saving the mobility restriction parameters; the mobility restriction parameter storage network element being an anchor paging controller, or an anchor authenticator, or a function entity including a function of the anchor paging controller and a function of the anchor authenticator.

Abstract: A method for treating highly concentrated resin-desorption liquid generated from wastewater deep purification, including channeling the highly concentrated desorption liquid generated from anion exchange resin treatment through a nanofiltration membrane, the liquid being separated into nanofiltration permeate that can be reused as the desorption agent and highly concentrated nanofiltration retentate; adding a coagulating agent to the highly concentrated nanofiltration retentate to generate coagulation-precipitation; subjecting the supernatant formed after the coagulation-precipitation process to Fenton oxidation or ozone oxidation; after the reaction, adding to the liquid an alkali solution for further coagulation-precipitation; then channeling the liquid so treated back to the biochemical system of biochemical effluent treatment for further biodegradation is provided.

Abstract: A circuit for preheating filaments may include: a transistor; a first winding, one terminal of which being electrically connected with a collector of the transistor, and the other terminal being connected to an input of a power source; a second winding, one terminal of which being electrically connected with an emitter of the transistor, the other terminal being electrically connected with a base of the transistor, and the second winding being coupled with the first winding in a self-excitation mode; one or more load windings respectively connected with the filaments in series, and each of which being coupled with the first winding in a flyback mode; and a delay switch, configured to change into an on state from an off state when a trigger signal with a predetermined delay is received, so as to turn off the transistor.

Abstract: The present disclosure provides compositions for eliciting an immune response, including a prophylactic immune response, against human immunodeficiency virus. The composition includes nucleic acid constructs encoding HIV antigenic polypeptides of multiple clades or strains. Methods for eliciting an immune response by administering the composition to a subject are also provided.

Abstract: The present invention relates to methods, kits, probes, and systems for distinguishing between nucleotide variants that are close in proximity on a gene. The methods, kits, probes, and systems can include the use of a small amplicon assay in combination with two unlabeled probes in a high resolution thermal melting analysis of a biological sample containing a locus of interest in order to discern between disease-causing and benign variants that are close in proximity on a gene within the biological sample. The present invention also relates to method of detecting a disease in a patient based on the patient's genotype by determining whether the patient has a disease-causing variant at a locus of interest. The signature melt curves produced by the unlabeled probe tests can be analyzed using HRMA software to distinguish between disease-causing and benign variants that are close in proximity on a gene within the biological sample.

Abstract: A process for the preparation of ranolazine comprises the step of condensing N-(2,6-dimethylphenyl)-1-piperazinyl acetamide with a compound of formula (I) to obtain ranolazine, in which X is chlorine or bromine Ranolazine is prepared by condensing ring-opening halide which replaces epoxide in this process.

Abstract: The disclosure provides an anchor authenticator relocation method and system. The method includes: after an old authenticator accepts an anchor authenticator relocation request of a Mobile Station (MS), a new authenticator sends an authenticator relocation request to an AAA server; when the AAA server's verification on the new authenticator is passed and the old authenticator confirms that the new authenticator is trusted, the anchor authenticator is relocated to the new authenticator. The disclosure provides a detailed solution to perform anchor authenticator relocation without re-authentication.

Abstract: The disclosure provides a method and a system for processing an authenticator relocation request. When detecting that initial authentication, re-authentication or authenticator relocation is being performed for a terminal, a network side refuses a new authenticator relocation request from the terminal. When detecting that no initial authentication, re-authentication or authenticator relocation is being performed for the terminal, the network side accepts the new authenticator relocation request from the terminal. Further, when detecting that the initial authentication, the re-authentication or the authenticator relocation is being performed for the terminal, the network side refuses a new re-authentication request from the terminal. According to the technical solution of the disclosure, the complexity of network element processing is reduced and potential safety hazard is avoided.

Abstract: The disclosure discloses a method for managing network topology structure of a Machine to Machine (M2M) network. The method mainly includes: a control station of the M2M network obtains wireless link information of the M2M network; the control station completes establishment and/or adjustment of the network topology structure of the M2M network according to the obtained wireless link information. The disclosure also provides a device for managing network topology structure of an M2M network. By the disclosure, performing self-adaptive management on numerous terminals can be realized by the M2M network; by applying the disclosure to the wireless network management of the M2M network, manpower cost is saved and working efficiency is improved, and also it is of important significance to the smooth development of the telecom operation.

Abstract: A method for improving transmission efficiency of physical layer attributes in a wireless communication system is proposed, and the method comprises the following steps of: (a) defining one or more sets of physical layer channel basic attributes that must be supported, and each set being respectively represented by a value of a domain of attributes, that is, a value of Profile; (b) a transmitting apparatus sending a physical layer channel description information, wherein the value of Profile is used to represent the physical layer channel basic attributes supported by the apparatus; (c) after receiving the channel description information, based on the value of Profile within the information, a receiving apparatus judging whether a set of physical layer channel basic attributes corresponding to the value is supported.

Abstract: Stabilized forms of gp120 polypeptide, nucleic acids encoding these stabilized forms, vectors comprising these nucleic acids, and methods of using these polypeptides, nucleic acids, vectors and host cells are disclosed. Crystal structures and computer systems including atomic coordinates for stabilized forms of gp120, and gp120 with an extended V3 loop, and methods of using these structures and computer systems are also disclosed.

Abstract: A method for accelerating network accessing of a terminal in a wireless communication system, comprises: a wireless terminal receiving system parameter information, and after obtaining system information of a base station identifier (BS ID) and a network access provider identifier (NAP ID), immediately judging validity of the NAP ID, or validity of both the NAP ID and the BS ID; if a result of the judgment is “valid”, the terminal proceeding to a subsequent procedure of the network discovery and selection according to information stored in the terminal, otherwise, carrying out a new procedure of network discovery and selection. The method avoids continuing to perform processes such as message receiving and decoding in the case that a NAP ID or a BS ID is invalid according to a procedure in the current protocol, thereby increasing the speed of network accessing of a terminal.

Abstract: The disclosure discloses a method for positioning a mobile terminal, which comprises: a server sends a push notification to a mobile terminal; the mobile terminal performs self-positioning after receiving the push notification, to acquire geographical position information regarding the mobile terminal, and sends the geographical position information to the server; the server receives and displays the geographical position information sent by the mobile terminal. The disclosure also discloses a system for positioning a mobile terminal for implementing the method for positioning a mobile terminal and a mobile terminal. With such method and device, the server can be used to send a push notification to the mobile terminal after a user finds that the mobile terminal is lost. The mobile terminal positions geographical position information thereof and sends the geographical position information to the server to help the user retrieve the mobile terminal.