Patents by Inventor Linheng Li

Linheng Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12186332
    Abstract: The present disclosure provides, inter alia, methods for treating cancers including leukemia using low doses of an anthracycline such as doxorubicin.
    Type: Grant
    Filed: June 26, 2020
    Date of Patent: January 7, 2025
    Assignees: Stowers Institute for Medical Research, The Children's Mercy Hospital, University of Kansas
    Inventors: Linheng Li, John M. Perry, Fang Tao, Xi C. He, Anuradha Roy, Scott J. Weir, Tara Lin
  • Publication number: 20240409114
    Abstract: Provided herein is technology relating to a function allocation system (FAS) that deploys artificial intelligence models for a connected automated highway (CAH) system and a connected automated vehicle (CAV) system to distribute driving intelligence between the CAV system and the CAH system. The FAS comprises a communication module, a data module, and a computing module. The computing module is configured to analyse scenes using sensing data, determine automated driving function requirements, deploy function allocation methods, and analyse CAH system and CAV system functions. The function allocation methods provide analysis, guidance, and optimization capabilities for sensing, decision-making, and control functions. The FAS allocates automated driving functions to the CAV system and the CAH system based on their respective intelligence levels.
    Type: Application
    Filed: August 20, 2024
    Publication date: December 12, 2024
    Inventors: Bin Ran, Peipei Mao, Jingwen Zhu, Wenqi Lu, Ziwei Yi, Linheng Li, Yang Cheng, Yuan Zheng, Keshu Wu, Linghui Xu, Tianyi Chen, Haotian Shi
  • Publication number: 20240359708
    Abstract: Provided herein is an artificial intelligence-based mobile roadside intelligent unit (MRIU) for providing, supplementing, and/or enhancing the control and operation of autonomous vehicles in normal and long-tail scenarios. The MRIU comprises a computing module configured to provide supplemental computation capability for autonomous driving. The MRIU comprises a communication module to communicate and exchange data with a vehicle or a cloud. The MRIU provides prediction, decision-making, and/or control functions for autonomous driving. The MRIU provides edge computing capability for autonomous vehicles to train and operate artificial intelligence-based intelligent driving models in a distributed fashion. Specifically, an edge computing unit conducts data fusion and data feature extraction, provides prediction, formulates control strategies, generates vehicle control instructions, and/or distributes vehicle control information and/or instructions for an autonomous vehicle.
    Type: Application
    Filed: July 10, 2024
    Publication date: October 31, 2024
    Inventors: Bin Ran, Wenqi Lu, Bingjie Liang, Linheng Li, Ziwei Yi, Tianyi Chen, Yang Cheng, Yifan Yao, Keshu Wu, Kunsong Shi
  • Publication number: 20240343269
    Abstract: This technology relates to autonomous vehicle (AV) control systems tailored for critical points of a partially instrumented infrastructure. The first system integrates an onboard unit (OBU) and communication modules to interact with roadside units (RSUs) or a cloud platform, delivering time-sensitive control instructions to vehicles at critical points. The OBUs execute these instructions for driving tasks. The second system combines an OBU with a cloud platform, leveraging cloud services for enhanced functionality like storage and computing. It adapts to diverse critical point scenarios, employing proactive incident prediction and rapid detection methods for optimized performance.
    Type: Application
    Filed: April 8, 2024
    Publication date: October 17, 2024
    Inventors: Bin Ran, Peipei Mao, Linheng Li, Yang Cheng, Tianyi Chen, Yang Zhou, Zhen Zhang, Xiaotian Li, Shen Li, Shuoxuan Dong, Kunsong Shi
  • Patent number: 12077175
    Abstract: Provided herein is technology relating to intelligent transportation systems and automated vehicles and particularly, but not exclusively, to function allocation systems and methods for a connected automated vehicle highway system that provides transportation management and operations and vehicle control for connected and automated vehicles.
    Type: Grant
    Filed: October 12, 2021
    Date of Patent: September 3, 2024
    Assignee: CAVH LLC
    Inventors: Bin Ran, Peipei Mao, Wenqi Lu, Ziwei Yi, Linheng Li, Yang Cheng, Linghui Xu, Yuan Zheng, Tianyi Chen, Haotian Shi, Keshu Wu
  • Patent number: 12043288
    Abstract: Provided herein is technology relating to automated driving and particularly, but not exclusively, to a mobile intelligent road infrastructure technology configured to serve automated driving systems by providing, supplementing, and/or enhancing autonomous driving functions for connected automated vehicles under common and unusual driving scenarios.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: July 23, 2024
    Assignee: CAVH LLC
    Inventors: Bin Ran, Wenqi Lu, Tianyi Chen, Yang Cheng, Linheng Li, Bingjie Liang, Yifan Yao, Kunsong Shi, Keshu Wu
  • Publication number: 20220281484
    Abstract: Provided herein is technology relating to automated driving and particularly, but not exclusively, to a mobile intelligent road infrastructure technology configured to serve automated driving systems by providing, supplementing, and/or enhancing autonomous driving functions for connected automated vehicles under common and unusual driving scenarios.
    Type: Application
    Filed: February 18, 2022
    Publication date: September 8, 2022
    Inventors: Bin Ran, Wenqi Lu, Tianyi Chen, Yang Cheng, Linheng Li, Bingjie Liang, Yifan Yao, Kunsong Shi, Keshu Wu
  • Publication number: 20220171400
    Abstract: The technology relates to a systematic intelligent system (SIS) configured to share data and allocate computing resources among automated driving systems (ADS), e.g., using unified data specifications and interfaces. The SIS comprises systematic intelligent units (STU) that serve components of ADS, including vehicle intelligent units (VIU) and roadside intelligent units (RIU), and is configured to perform methods to serve an entire trip.
    Type: Application
    Filed: November 30, 2021
    Publication date: June 2, 2022
    Inventors: Tianyi Chen, Bin Ran, Shuoxuan Dong, Keshu Wu, Yang Cheng, Linheng Li, Shen Li, Xiaotian Li, Yanghui Mo, Yifan Yao, Kunsong Shi, Haotian Shi, Hanchu Li
  • Publication number: 20220111858
    Abstract: Provided herein is technology relating to intelligent transportation systems and automated vehicles and particularly, but not exclusively, to function allocation systems and methods for a connected automated vehicle highway system that provides transportation management and operations and vehicle control for connected and automated vehicles.
    Type: Application
    Filed: October 12, 2021
    Publication date: April 14, 2022
    Inventors: Bin Ran, Peipei Mao, Wenqi Lu, Ziwei Yi, Linheng Li, Yang Cheng, Linghui Xu, Yuan Zheng, Tianyi Chen, Haotian Shi, Keshu Wu
  • Patent number: 11173173
    Abstract: The disclosure provides methods of treating cancer by selectively inhibiting p-S552-?-catenin, p-T217-?-catenin, p-T332-?-catenin, and/or p-S675-?-catenin production and/or activity. Such methods also and/or limit cancer-initiating cells.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: November 16, 2021
    Assignees: UNIVERSITY OF CONNECTICUT, UNIVERSITY OF KANSAS, STOWERS INSTITUTE FOR MEDICAL RESEARCH
    Inventors: Rajeswari Kasi, Linheng Li, Xiuling Lu, John M. Perry, Gurusingham Sitta Sittampalam, Anuradha Roy, Xi C. He
  • Publication number: 20210113597
    Abstract: The present disclosure provides, inter alia, methods for treating cancers including leukemia using low doses of an anthracycline such as doxorubicin.
    Type: Application
    Filed: June 26, 2020
    Publication date: April 22, 2021
    Inventors: Linheng Li, John M. Perry, Fang Tao, Xi C. He, Anuradha Roy, Scott J. Weir, Tara Lin
  • Publication number: 20200370044
    Abstract: The present invention relates to methods for expanding a stem cell population, as well as other cell populations. More particularly, the invention relates, inter alia, to methods and compositions for expanding a stem cell and/or other cell population, particularly a hematopoietic stem cell population.
    Type: Application
    Filed: October 9, 2018
    Publication date: November 26, 2020
    Inventors: Zhenrui Li, Pengxu Qian, Linheng Li, Chuan He
  • Patent number: 10787643
    Abstract: The present invention relates to methods and kits for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods, kits, and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: September 29, 2020
    Assignee: STOWERS INSTITUTE FOR MEDICAL RESEARCH
    Inventors: John M. Perry, Linheng Li, Justin C. Grindley
  • Publication number: 20180072991
    Abstract: The present invention relates to methods for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Application
    Filed: August 22, 2017
    Publication date: March 15, 2018
    Inventors: John M. PERRY, Linheng LI, Justin C. GRINDLEY
  • Patent number: 9896659
    Abstract: Methods and kits for expanding a stem cell population, particularly a hematopoietic stem cell population, in the presence of a DNA methyltransferase modulator and a Wnt pathway modulator are disclosed.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: February 20, 2018
    Assignee: STOWERS INSTITUTE FOR MEDICAL RESEARCH
    Inventors: John M Perry, Linheng Li, Aparna Venkatraman, Xi He
  • Patent number: 9771559
    Abstract: The present invention relates to methods for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Grant
    Filed: May 20, 2013
    Date of Patent: September 26, 2017
    Assignee: Stowers Institute for Medical Research
    Inventors: John M. Perry, Linheng Li, Justin C. Grindley
  • Publication number: 20160355784
    Abstract: The present invention relates to methods and kits for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods, kits, and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Application
    Filed: May 17, 2016
    Publication date: December 8, 2016
    Inventors: John M. Perry, Linheng Li, Justin C. Grindley
  • Patent number: 9334315
    Abstract: The present invention relates to a purified molecules, including antibodies, that bind specifically to murine ?-catenin phosphorylated at amino acid position Serine552 and to orthologs thereof, such as mammalian orthologs, including human orthologs. Methods of making and using such purified molecules are also provided. Kits containing such purified molecules are further provided.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: May 10, 2016
    Assignees: Stowers Institute for Medical Research, Institute For Systems Biology
    Inventors: Xi He, Tong Yin, Qiang Tian, Weiguo Tao, Leroy Hood, Linheng Li
  • Publication number: 20150344845
    Abstract: The present invention relates to methods and kits for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods, kits, and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Application
    Filed: February 27, 2015
    Publication date: December 3, 2015
    Inventors: John M. Perry, Linheng Li, Justin Campos Grindley
  • Publication number: 20140255359
    Abstract: Methods and kits for expanding a stem cell population, particularly a hematopoietic stem cell population, in the presence of a DNA methyltransferase modulator and a Wnt pathway modulator are disclosed.
    Type: Application
    Filed: October 17, 2012
    Publication date: September 11, 2014
    Inventors: John M. Perry, Linheng Li, Aparna Venkatraman, Xi He