Patents by Inventor Linheng Li

Linheng Li has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MOBILE INTELLIGENT ROAD INFRASTRUCTURE SYSTEM
    Publication number: 20220281484
    Abstract: Provided herein is technology relating to automated driving and particularly, but not exclusively, to a mobile intelligent road infrastructure technology configured to serve automated driving systems by providing, supplementing, and/or enhancing autonomous driving functions for connected automated vehicles under common and unusual driving scenarios.
    Type: Application
    Filed: February 18, 2022
    Publication date: September 8, 2022
    Inventors: Bin Ran, Wenqi Lu, Tianyi Chen, Yang Cheng, Linheng Li, Bingjie Liang, Yifan Yao, Kunsong Shi, Keshu Wu
  • SYSTEMATIC INTELLIGENT SYSTEM
    Publication number: 20220171400
    Abstract: The technology relates to a systematic intelligent system (SIS) configured to share data and allocate computing resources among automated driving systems (ADS), e.g., using unified data specifications and interfaces. The SIS comprises systematic intelligent units (STU) that serve components of ADS, including vehicle intelligent units (VIU) and roadside intelligent units (RIU), and is configured to perform methods to serve an entire trip.
    Type: Application
    Filed: November 30, 2021
    Publication date: June 2, 2022
    Inventors: Tianyi Chen, Bin Ran, Shuoxuan Dong, Keshu Wu, Yang Cheng, Linheng Li, Shen Li, Xiaotian Li, Yanghui Mo, Yifan Yao, Kunsong Shi, Haotian Shi, Hanchu Li
  • FUNCTION ALLOCATION FOR AUTOMATED DRIVING SYSTEMS
    Publication number: 20220111858
    Abstract: Provided herein is technology relating to intelligent transportation systems and automated vehicles and particularly, but not exclusively, to function allocation systems and methods for a connected automated vehicle highway system that provides transportation management and operations and vehicle control for connected and automated vehicles.
    Type: Application
    Filed: October 12, 2021
    Publication date: April 14, 2022
    Inventors: Bin Ran, Peipei Mao, Wenqi Lu, Ziwei Yi, Linheng Li, Yang Cheng, Linghui Xu, Yuan Zheng, Tianyi Chen, Haotian Shi, Keshu Wu
  • Methods for treating chemoresistant cancer-initiating cells
    Patent number: 11173173
    Abstract: The disclosure provides methods of treating cancer by selectively inhibiting p-S552-?-catenin, p-T217-?-catenin, p-T332-?-catenin, and/or p-S675-?-catenin production and/or activity. Such methods also and/or limit cancer-initiating cells.
    Type: Grant
    Filed: July 28, 2016
    Date of Patent: November 16, 2021
    Assignees: UNIVERSITY OF CONNECTICUT, UNIVERSITY OF KANSAS, STOWERS INSTITUTE FOR MEDICAL RESEARCH
    Inventors: Rajeswari Kasi, Linheng Li, Xiuling Lu, John M. Perry, Gurusingham Sitta Sittampalam, Anuradha Roy, Xi C. He
  • METHODS FOR OVERCOMING WNT/BETA-CATENIN ANTI-CANCER RESISTANCE IN LEUKEMIA STEM CELLS
    Publication number: 20210113597
    Abstract: The present disclosure provides, inter alia, methods for treating cancers including leukemia using low doses of an anthracycline such as doxorubicin.
    Type: Application
    Filed: June 26, 2020
    Publication date: April 22, 2021
    Inventors: Linheng Li, John M. Perry, Fang Tao, Xi C. He, Anuradha Roy, Scott J. Weir, Tara Lin
  • METHODS AND COMPOSITIONS FOR EXPANSION OF CELL POPULATION
    Publication number: 20200370044
    Abstract: The present invention relates to methods for expanding a stem cell population, as well as other cell populations. More particularly, the invention relates, inter alia, to methods and compositions for expanding a stem cell and/or other cell population, particularly a hematopoietic stem cell population.
    Type: Application
    Filed: October 9, 2018
    Publication date: November 26, 2020
    Inventors: Zhenrui Li, Pengxu Qian, Linheng Li, Chuan He
  • Methods, kits, and compositions for stem cell self-renewal
    Patent number: 10787643
    Abstract: The present invention relates to methods and kits for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods, kits, and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: September 29, 2020
    Assignee: STOWERS INSTITUTE FOR MEDICAL RESEARCH
    Inventors: John M. Perry, Linheng Li, Justin C. Grindley
  • METHODS AND COMPOSITIONS FOR STEM CELL SELF-RENEWAL
    Publication number: 20180072991
    Abstract: The present invention relates to methods for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Application
    Filed: August 22, 2017
    Publication date: March 15, 2018
    Inventors: John M. PERRY, Linheng LI, Justin C. GRINDLEY
  • Methods, kits, and compositions for stem cell self-renewal
    Patent number: 9896659
    Abstract: Methods and kits for expanding a stem cell population, particularly a hematopoietic stem cell population, in the presence of a DNA methyltransferase modulator and a Wnt pathway modulator are disclosed.
    Type: Grant
    Filed: October 17, 2012
    Date of Patent: February 20, 2018
    Assignee: STOWERS INSTITUTE FOR MEDICAL RESEARCH
    Inventors: John M Perry, Linheng Li, Aparna Venkatraman, Xi He
  • Methods and compositions for stem cell self-renewal
    Patent number: 9771559
    Abstract: The present invention relates to methods for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Grant
    Filed: May 20, 2013
    Date of Patent: September 26, 2017
    Assignee: Stowers Institute for Medical Research
    Inventors: John M. Perry, Linheng Li, Justin C. Grindley
  • Methods, Kits, and Compositions for Stem Cell Self-Renewal
    Publication number: 20160355784
    Abstract: The present invention relates to methods and kits for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods, kits, and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Application
    Filed: May 17, 2016
    Publication date: December 8, 2016
    Inventors: John M. Perry, Linheng Li, Justin C. Grindley
  • Method of detecting phosphorylation state of beta-catenin
    Patent number: 9334315
    Abstract: The present invention relates to a purified molecules, including antibodies, that bind specifically to murine ?-catenin phosphorylated at amino acid position Serine552 and to orthologs thereof, such as mammalian orthologs, including human orthologs. Methods of making and using such purified molecules are also provided. Kits containing such purified molecules are further provided.
    Type: Grant
    Filed: December 15, 2011
    Date of Patent: May 10, 2016
    Assignees: Stowers Institute for Medical Research, Institute For Systems Biology
    Inventors: Xi He, Tong Yin, Qiang Tian, Weiguo Tao, Leroy Hood, Linheng Li
  • METHODS, KITS, AND COMPOSITIONS FOR STEM CELL SELF-RENEWAL
    Publication number: 20150344845
    Abstract: The present invention relates to methods and kits for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods, kits, and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Application
    Filed: February 27, 2015
    Publication date: December 3, 2015
    Inventors: John M. Perry, Linheng Li, Justin Campos Grindley
  • METHODS, KITS, AND COMPOSITIONS FOR STEM CELL SELF-RENEWAL
    Publication number: 20140255359
    Abstract: Methods and kits for expanding a stem cell population, particularly a hematopoietic stem cell population, in the presence of a DNA methyltransferase modulator and a Wnt pathway modulator are disclosed.
    Type: Application
    Filed: October 17, 2012
    Publication date: September 11, 2014
    Inventors: John M. Perry, Linheng Li, Aparna Venkatraman, Xi He
  • METHODS AND COMPOSITIONS FOR STEM CELL SELF-RENEWAL
    Publication number: 20130252338
    Abstract: The present invention relates to methods for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Application
    Filed: May 20, 2013
    Publication date: September 26, 2013
    Applicant: Stowers Institute for Medical Research
    Inventors: John M. PERRY, Linheng LI, Justin C. GRINDLEY
  • Methods and compositions for stem cell self-renewal
    Patent number: 8476071
    Abstract: The present invention relates to methods for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Grant
    Filed: August 9, 2012
    Date of Patent: July 2, 2013
    Assignee: Stowers Institute for Medical Research
    Inventors: John M. Perry, Linheng Li, Justin C. Grindley
  • METHODS AND COMPOSITIONS FOR STEM CELL SELF-RENEWAL
    Publication number: 20120309088
    Abstract: The present invention relates to methods for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Application
    Filed: August 9, 2012
    Publication date: December 6, 2012
    Inventors: John M. Perry, Linheng Li, Justin C. Grindley
  • Methods and compositions for stem cell self-renewal
    Patent number: 8263403
    Abstract: The present invention relates to methods for expanding a stem cell population. More particularly, the invention relates, inter alia, to methods and compositions for expanding a stem cell population, particularly a hematopoietic stem cell population.
    Type: Grant
    Filed: April 23, 2008
    Date of Patent: September 11, 2012
    Assignee: Stowers Institute for Medical Research
    Inventors: John M. Perry, Linheng Li, Justin C. Grindley
  • PTEN/AKT METHODS AND COMPOSITIONS RELATING TO BMP
    Publication number: 20120115172
    Abstract: The present invention relates to a purified molecules, including antibodies, that bind specifically to murine ?-catenin phosphorylated at amino acid position Serine552 and to orthologs thereof, such as mammalian orthologs, including human orthologs. Methods of making and using such purified molecules are also provided. Kits containing such purified molecules are further provided.
    Type: Application
    Filed: December 15, 2011
    Publication date: May 10, 2012
    Inventors: Xi HE, Tong Yin, Qiang Tian, Weiguo Tao, Leroy Hood, Linheng Li
  • Antibodies that bind specifically to phosphorylated ?-catenin
    Patent number: 8106166
    Abstract: The present invention relates to a purified molecules, including antibodies, that bind specifically to murine ?-catenin phosphorylated at amino acid position Serine552 and to orthologs thereof, such as mammalian orthologs, including human orthologs. Methods of making and using such purified molecules are also provided. Kits containing such purified molecules are further provided.
    Type: Grant
    Filed: March 17, 2008
    Date of Patent: January 31, 2012
    Assignee: Stowers Institute for Medical Research
    Inventors: Xi He, Tong Yin, Qiang Tian, Weiguo Tao, Leroy Hood, Linheng Li