Patents by Inventor Liping Zhang

Liping Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10442904
    Abstract: A method for preparing a chitosan complex film comprises: (1) reacting polyvinyl alcohol-124 with butanedioic anhydride to obtain a modified polyvinyl alcohol; (2) formulating the modified polyvinyl alcohol-124 into a 0.4 wt % aqueous solution, then adding the aqueous solution containing 0.4 wt % of modified polyvinyl alcohol-124 dropwise into an acetic acid solution at a concentration of 0.4 wt % chitosan to obtain a mixed solution; (3) adjusting the pH value of the mixed solution with a 0.01 wt % NaOH solution to pH 5.5, and removing surface bubbles after standing for one hour to obtain a casting solution; (4) pouring the casting solution into a culture dish, placing the culture dish into an oven at 60° C. and drying to a constant weight to obtain the chitosan complex film. The materials used in the method are inexpensive, and the reaction is not complicated, so the cost of the product is not high.
    Type: Grant
    Filed: May 27, 2015
    Date of Patent: October 15, 2019
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Caihua Ni, Lei Tao, Liping Zhang
  • Patent number: 10378147
    Abstract: The present invention provides a novel pretreating agent to improve the effect of ink-jet printing on polyester fabric and its application, and this invention belongs to the field of digital ink-jet printing. Stirring the dispersing agent, which includes many procedures of wetting agent and deionized water in a stirrer, adding nano-porous oxide dispersoid. Furthermore, keep stirring for 30 min and put the mixture in a sand mill to grinded for 2 h, then nano-porous oxide dispersoid is eventually got. The nano-porous oxide dispersoid work as pretreating agent, which used in the polyester fabric, is treated like pretreating agent during the padding process. By applying this technique into double-sided permeation ink-jet printing and direct-injection ink-jet printing, its pattern's definition, color depth and color saturation could be remarkable enhanced.
    Type: Grant
    Filed: November 2, 2017
    Date of Patent: August 13, 2019
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Shaohai Fu, Min Li, Liping Zhang, Ying Zhao, Ying Tan, Anli Tian
  • Publication number: 20190194471
    Abstract: Disclosed is a method for preparing self-dispersing nano carbon black based on a thiol-ene click reaction. A sol-gel technique is used to graft a coupling agent containing a carbon-carbon double bond onto the surface of the carbon black, and a functional molecular chain is grafted onto the surface of the carbon black by a thiol-ene click reaction with a mercapto compound. The self-dispersing nano carbon black is obtained after centrifugation, washing and drying. The method is simple and easy to operate, has a high grafting rate, and can prepare self-dispersing nano carbon black adaptable to different systems by selecting mercapto compounds with different functional groups.
    Type: Application
    Filed: November 1, 2018
    Publication date: June 27, 2019
    Applicant: Jiangnan University
    Inventors: Shaohai Fu, Liping Zhang, Liangan Wang, Chunxia Wang, Min Li
  • Publication number: 20190144417
    Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
    Type: Application
    Filed: May 4, 2017
    Publication date: May 16, 2019
    Inventors: David K. WILLIAMS, Weifanq SHAN, Liping ZHANG, Emily Charlotte CHERNEY, James Aaron BALOG
  • Publication number: 20190135758
    Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
    Type: Application
    Filed: May 4, 2017
    Publication date: May 9, 2019
    Inventors: Emily Charlotte CHERNEY, Weifang SHAN, Liping ZHANG, David K. WILLIAMS, Weiwei GUO, Audris HUANG, James Aaron BALOG
  • Publication number: 20190140126
    Abstract: A light reflective film, a processing method and a photovoltaic cell module. The vertex height of a prism and/or the bottom width of the prism change periodically to form a polyhedral structure, and the adjacent faces can present a mirror structure, so that the entire prism can reflect both morning and afternoon sunlight, which leads to improved reflection efficiency throughout the work period. In the prior art, the reflective surface of the straight triangular prism has a constant angle with respect to the axis of the working plane of a photovoltaic cell module, therefore, it only has high reflection efficiency for the sunlight at a certain time; the granular reflective micro-structure, such as a triangular pyramid, can be aligned with the sunlight on two sides thereof to reflect the sunlight in the morning and afternoon, but there are many blank areas between the granules.
    Type: Application
    Filed: June 13, 2018
    Publication date: May 9, 2019
    Inventors: Liping ZHANG, Rui GAO, Jing DING
  • Publication number: 20190130040
    Abstract: Embodiments described herein provide a solution for optimizing a generating of query search results. A filtering search term (e.g., a search term that is used in a query to perform filtering aggregations of the query search results) is identified. A filtering bitmap that has a plurality of mapped locations corresponding to data values for the filtering search term is created. As a data value in the filtering search term is encountered during a scan of the query search results, the corresponding mapped location is updated. Each mapped location in the filtering bitmap is read to determine whether the value corresponding to the mapped location satisfies the filtering aggregation. The filtering aggregation can then be performed (e.g., prior to any grouping aggregation) by removing any of the query search results determined, based on the filtering bitmap, as having data values for which the filtering aggregation is not satisfied.
    Type: Application
    Filed: November 1, 2017
    Publication date: May 2, 2019
    Inventors: Wenbin Ma, Liping Zhang, Calisto Zuzarte
  • Publication number: 20190119216
    Abstract: There are disclosed compounds that modulate or inhibit the enzymatic activity of indoleamine 2,3-dioxygenase (IDO), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders, such as cancer, viral infections and/or inflammatory disorders utilizing the compounds of the invention.
    Type: Application
    Filed: May 4, 2017
    Publication date: April 25, 2019
    Inventors: Emily Charlotte CHERNEY, Liping ZHANG, David K. WILLIAMS, James Aaron BALOG
  • Publication number: 20190110987
    Abstract: Hybrid amphiphilic star copolymer nano micelles are prepared in the invention. Cage shaped octa(?-aminopropyl) silsesquioxanes is selected as the inorganic part, and L-glutamic benzyl ester-five membered ring anhydride is ring-opening polymerized by the initiation of amino groups on the surface of cage shaped octa(?-aminopropyl) silsesquioxanes, producing copolymers with cage shaped octa(?-aminopropyl) silsesquioxanes as nucleus and poly (L-glutamic-benzyl ester) as arms. The copolymers reacts with monomethoxy poly (ethylene glycol) carboxylic acid by condensation. Finally, the benzyl groups in the side chains of poly (L-glutamic acid-benzyl ester) are converted into hydrazine groups by acylhydrazination to obtain hybrid amphiphilic star copolymer nano micelles. The micelles can load doxorubicin, they are safe to human body and have good application prospects.
    Type: Application
    Filed: October 12, 2018
    Publication date: April 18, 2019
    Inventors: Liping ZHANG, Caihua NI, Ren LIU, He LIU, Xinyi DONG
  • Publication number: 20190091147
    Abstract: Disclosed is a preparation method for charge reversal and reversibly crosslinked redox-sensitive nanomicelles, falling within the technical field of biomedical materials. The method comprises: synthesizing thiocinamide from lipoic acid and ethylenediamine under an N,N?-carbonyl diimidazole catalyst; and polymerizing thiocinamide, polyethylene glycol diglycidyl ether and lysine through a nucleophilic addition mechanism to prepare a poly(lysine-co-polyethylene glycol diglycidyl ether-co-thiocinamide) terpolymer. The micelle is endowed with excellent anti-protein nonspecific adsorption and enhanced cell uptake property through a self-assembly and protonation/deprotonation action; and a disulfide bond in lipoyl may form a linear polydisulfide structure under the action of 1,4-dithiothreitol, so that a micelle core is crosslinked, and a crosslinked structure is destroyed in the cell under a redox condition, and controlled release of a drug can be achieved.
    Type: Application
    Filed: April 27, 2017
    Publication date: March 28, 2019
    Inventors: Liping ZHANG, Ren LIU, Caihua NI, Yuanyuan Ding, Gang SHI, Xinxin Sang
  • Patent number: 10236162
    Abstract: A method of etching a porous film is provided. The method includes supplying a first gas into a processing chamber of a plasma processing apparatus in which an object to be processed including a porous film is accommodated, and generating a plasma of a second gas for etching the porous film in the processing chamber. The first gas is a processing gas having a saturated vapor pressure of less than or equal to 133.3 Pa at a temperature of a stage on which the object is mounted in the processing chamber, or includes the processing gas. In the step of supplying the first gas, no plasma is generated, and a partial pressure of the processing gas which is supplied into the processing chamber is set to be greater than or equal to 20% of the saturated vapor pressure.
    Type: Grant
    Filed: November 29, 2017
    Date of Patent: March 19, 2019
    Assignee: TOKYO ELECTRON LIMITED
    Inventors: Shigeru Tahara, Eiichi Nishimura, Mikhail Baklanov, Liping Zhang, Jean-Francois de Marneffe
  • Patent number: 10206893
    Abstract: Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
    Type: Grant
    Filed: February 1, 2017
    Date of Patent: February 19, 2019
    Assignee: Flexus Biosciences, Inc.
    Inventors: Hilary Plake Beck, Juan Carlos Jaen, Maksim Osipov, Jay Patrick Powers, Maureen Kay Reilly, Hunter Paul Shunatona, James Ross Walker, Mikhail Zibinsky, James Aaron Balog, David K. Williams, Jay A. Markwalder, Steven P. Seitz, Emily Charlotte Cherney, Liping Zhang, Weifang Shan, Weiwei Guo, Audris Huang
  • Publication number: 20190008775
    Abstract: The present invention relates to a preparation method for modified sodium alginate embolization microspheres and a method for carrying an anti-cancer drug doxorubicin by means of modified sodium alginate embolization microspheres. The preparation method includes the following steps: (1) sodium alginate is modified by using taurine, so that modified sodium alginate is synthesized; (2) with high-concentration aqueous modified sodium alginate solution as a water phase, mineral oil as an oil phase and polyaldehyde cellulose as a crosslinking agent, modified sodium alginate embolization microspheres are prepared by an inverse emulsification method.
    Type: Application
    Filed: January 13, 2017
    Publication date: January 10, 2019
    Inventors: Liping ZHANG, Ren LIU, Caihua NI, Xue BAI, Gang SHI
  • Patent number: 10176223
    Abstract: A computer-implemented method includes receiving a query plan. The method includes identifying a plurality of qualified relevant rows and one or more encoding candidate payload columns. The method includes analyzing the relevant rows in the encoding candidate payload columns to yield a count of distinct contents and a payload column width. The method includes estimating a cost and determining whether the cost is larger than an amount of available memory for on-the-fly encoding all of the plurality of encoding candidate payload columns. The method is responsive to the estimated cost being less than the amount of available memory, by on-the-fly encoding the encoding candidates and responsive to the estimated cost being greater than the amount of available memory by on-the-fly encoding fewer than all of the encoding candidates so as not to exceed the available memory, and leaving alone one or more remaining encoding candidate payload columns unencoded.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: January 8, 2019
    Assignee: International Business Machines Corporation
    Inventors: Gopi K. Attaluri, Vijayshankar Raman, David C. Sharpe, Richard S. Sidle, Liping Zhang
  • Patent number: 10176224
    Abstract: A computer-implemented method includes receiving a query plan. The method includes identifying a plurality of qualified relevant rows and one or more encoding candidate payload columns. The method includes analyzing the relevant rows in the encoding candidate payload columns to yield a count of distinct contents and a payload column width. The method includes estimating a cost and determining whether the cost is larger than an amount of available memory for on-the-fly encoding all of the plurality of encoding candidate payload columns. The method is responsive to the estimated cost being less than the amount of available memory, by on-the-fly encoding the encoding candidates and responsive to the estimated cost being greater than the amount of available memory by on-the-fly encoding fewer than all of the encoding candidates so as not to exceed the available memory, and leaving alone one or more remaining encoding candidate payload columns unencoded.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: January 8, 2019
    Assignee: International Business Machines Corporation
    Inventors: Gopi K. Attaluri, Vijayshankar Raman, David C. Sharpe, Richard S. Sidle, Liping Zhang
  • Publication number: 20180360753
    Abstract: Provided are a reducible degradable hyperbranched-polymer nanomicelle and a method for preparation thereof and an application thereof. Cystamine and polyethylene glycol diglycidyl ether are polymerized by means of a nucleophilic addition mechanism; in one step, a hyperbranched polymer alternatingly arising from cystamine and polyethylene glycol structural units is synthesized and obtained; then, a hyperbranched nanomicelle is formed by means of self-assembly during the process of dialysis. The hyperbranched-polymer chain segments contain both tertiary aminos and disulfide bond structural units and have pH- and reduction responsiveness, and the hyperbranched three-dimensional cavity structure imparts a drug-carrying ability to the nanomicelle.
    Type: Application
    Filed: July 29, 2016
    Publication date: December 20, 2018
    Inventors: Caihua NI, Yamin ZHOU, Liping ZHANG, Gang SHI
  • Publication number: 20180325889
    Abstract: Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.
    Type: Application
    Filed: November 5, 2015
    Publication date: November 15, 2018
    Inventors: Hilary Plake BECK, Juan Carlos JAEN, Maksim OSIPOV, Jay Patrick POWERS, Maureen Kay REILLY, Hunter Paul SHUNATONA, James Ross WALKER, Mikhail ZIBINSKY, James Aaron BALOG, David K. Williams, Jay A. MARKWALDER, Steven P. SEITZ, Emily Charlotte CHERNEY, Liping ZHANG, Weifang SHAN, Weiwei GUO, Audris HUANG
  • Patent number: 10108667
    Abstract: A computer-implemented method includes receiving a query plan. The method includes identifying a plurality of qualified relevant rows and one or more encoding candidate payload columns. The method includes analyzing the relevant rows in the encoding candidate payload columns to yield a count of distinct contents and a payload column width. The method includes estimating a cost and determining whether the cost is larger than an amount of available memory for on-the-fly encoding all of the plurality of encoding candidate payload columns. The method is responsive to the estimated cost being less than the amount of available memory, by on-the-fly encoding the encoding candidates and responsive to the estimated cost being greater than the amount of available memory by on-the-fly encoding fewer than all of the encoding candidates so as not to exceed the available memory, and leaving alone one or more remaining encoding candidate payload columns unencoded.
    Type: Grant
    Filed: March 7, 2016
    Date of Patent: October 23, 2018
    Assignee: International Business Machines Corporation
    Inventors: Gopi K. Attaluri, Vijayshankar Raman, David C. Sharpe, Richard S. Sidle, Liping Zhang
  • Publication number: 20180276289
    Abstract: Provided herein are techniques for processing a database query aggregating data. Data tuples of a database object each including a grouping element and a data element are analyzed to determine a length of the data element for each data tuple. A plurality of tables each accommodate a successively greater length for the data element. A corresponding table of the plurality of tables to store each data tuple is determined based on the length of the data element of that data tuple relative to the accommodated lengths of the plurality of tables. Each data tuple in the determined corresponding table is stored to group the data tuples within each of the plurality of tables based on the grouping element, and an indication of corresponding tables containing members for each group is provided. The groups are combined across the plurality of tables to aggregate the data tuples for a database query.
    Type: Application
    Filed: March 22, 2017
    Publication date: September 27, 2018
    Inventors: Joshua D. Gross, Vincent Kulandaisamy, Wenbin Ma, Liping Zhang, Calisto P. Zuzarte
  • Publication number: 20180246806
    Abstract: To manage memory in a multi-processing system, a memory budget is assigned to each of a number of agents within the multi-processing system. A portion of memory is allocated to each the agents within the memory budget. Metrics are collected for each agent during processing of data by the agents; the metrics include an amount of data processed and an amount of memory used for each agent. Memory efficiency is determined for each agent based on the collected metrics and another memory budget is determined based on the memory efficiency. The portion of the memory is reallocated to the agents within the other memory budget in response to data stored in the memory relative to the assigned memory budget meeting a criterion.
    Type: Application
    Filed: February 28, 2017
    Publication date: August 30, 2018
    Inventors: Gopi K. Attaluri, Ronald J. Barber, Vijayshankar Raman, Liping Zhang