Abstract: There are disclosed compounds that are inhibitors of EZH2, pharmaceutical compositions containing said compounds and methods of treating hyperproliferative, inflammatory, infectious, and immunoregulatory disorders and diseases, utilizing the compounds of the invention.

Abstract: Methods of preparing a second high-efficiency, rhenium-promoted silver catalyst for producing alkylene oxide from an alkylene based on a first catalyst are disclosed and described. In accordance with the disclosed methods, the first and second catalysts include at least one promoter that includes a rhenium promoter. The target catalyst concentrations of one or more promoters of the at least one promoter on the second catalyst are determined based on the values of a catalyst reference property for the two catalysts and the concentration of the one or more promoters of the at least one promoter on the first catalyst. Suitable catalyst reference properties include carrier specific surface area and silver specific surface area. Reaction systems utilizing the first and second catalysts are also described.

Abstract: The invention relates generally to compounds that modulate the activity of TGF?R-1 and TGF?R-2, pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

Abstract: Embodiments relate to payload storage format for storing data in support of an aggregation function. As an input is subject to aggregation, the input is evaluated to ascertain a payload format for the aggregation. It is understood that there is more than one payload format. An evaluation of the aggregation key is a factor in the initial payload format. If the key is an addition to an existing aggregation, the evaluation considers changing the format of the payload to address processing and/or memory efficiency for the aggregation. The evaluation and the format change takes place dynamically so that the aggregation may continue.

Abstract: A method for the production of ethylene oxide wherein the partial pressure of water vapor at the inlet of the reactor is at least about 8 kPa using a high purity carrier comprising alpha-alumina, a promoting amount of at least one Group IA metal, and a promoting amount of rhenium.

Abstract: Embodiments of the invention relate to payload storage format for storing data in support of an aggregation function. As an input is subject to aggregation, the input is evaluated to ascertain a payload format for the aggregation. It is understood that there is more than one payload format. An evaluation of the aggregation key is a factor in the initial payload format. If the key is an addition to an existing aggregation, the evaluation considers changing the format of the payload to address processing and/or memory efficiency for the aggregation. The evaluation and the format change takes place dynamically so that the aggregation may continue.

Abstract: Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.

Abstract: A first query is detected. The first query is for a storage device, and pulls a result set from the storage device using a set of predicates. The first query satisfies a size criterion. A new set of predicates of the result set is identified. The new set of predicates does not include any predicates of the original set of predicates. A second query which is the same as the first query is detected. The new set of predicates is used to determine the result set.

Abstract: A first query is detected. The first query is for a storage device, and pulls a result set from the storage device using a set of predicates. The first query satisfies a size criterion. A new set of predicates of the result set is identified. The new set of predicates does not include any predicates of the original set of predicates. A second query which is the same as the first query is detected. The new set of predicates is used to determine the result set.

Abstract: Methods of preparing a second high-efficiency, rhenium-promoted silver catalyst for producing alkylene oxide from an alkylene based on a first catalyst are disclosed and described. In accordance with the disclosed methods, the first and second catalysts include at least one promoter that includes a rhenium promoter. The target catalyst concentrations of one or more promoters of the at least one promoter on the second catalyst are determined based on the values of a catalyst reference property for the two catalysts and the concentration of the one or more promoters of the at least one promoter on the first catalyst. Suitable catalyst reference properties include carrier specific surface area and silver specific surface area. Reaction systems utilizing the first and second catalysts are also described.

Abstract: A method for preparing a chitosan complex film comprises: (1) reacting polyvinyl alcohol-124 with butanedioic anhydride to obtain a modified polyvinyl alcohol; (2) formulating the modified polyvinyl alcohol-124 into a 0.4 wt % aqueous solution, then adding the aqueous solution containing 0.4 wt % of modified polyvinyl alcohol-124 dropwise into an acetic acid solution at a concentration of 0.4 wt % chitosan to obtain a mixed solution; (3) adjusting the pH value of the mixed solution with a 0.01 wt % NaOH solution to pH 5.5, and removing surface bubbles after standing for one hour to obtain a casting solution; (4) pouring the casting solution into a culture dish, placing the culture dish into an oven at 60° C. and drying to a constant weight to obtain the chitosan complex film. The materials used in the method are inexpensive, and the reaction is not complicated, so the cost of the product is not high.

Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

Abstract: Compounds that modulate the oxidoreductase enzyme indoleamine 2,3-dioxygenase, and compositions containing the compounds, are described herein. The use of such compounds and compositions for the treatment and/or prevention of a diverse array of diseases, disorders and conditions, including cancer- and immune-related disorders, that are mediated by indoleamine 2,3-dioxygenase is also provided.

Abstract: The disclosed technology generally relates to semiconductor fabrication, and more particularly to plasma etching of dielectric materials having pores. In one aspect, a method for etching a porous material in an environment includes contacting the porous material with an organic gas at a pressure and a temperature. The organic gas is such that at the pressure and the temperature, the organic gas remains in a gas state when outside of the porous material, while the organic gas condenses into an organic liquid upon contacting the porous material. Upon contacting the porous material, the organic gas thereby fills the pores of the porous material with the organic liquid. Subsequent to contacting the porous material, the method additionally includes plasma etch-treating of the porous material having filled pores, thereby evaporating a fraction of the organic liquid filling the pores of the porous material.

Abstract: A method for the production of ethylene oxide wherein the partial pressure of water vapor at the inlet of the reactor is at least about 8 kPa using a high purity carrier comprising alpha-alumina, a promoting amount of at least one Group IA metal, and a promoting amount of rhenium.

Abstract: The embodiment of the invention discloses a channel estimation method for a TD-SCDMA system. The channel estimation method comprises steps of: obtaining a coarse channel estimation of a channel 1 of an intra-frequency cell set by a single cell channel estimation algorithm; performing an interference cancellation on the coarse channel estimation to obtain a channel estimation; determining a channel environment according to the channel estimation; and determining a stop strategy for the interference cancellation according to the channel environment and controlling performing the interference cancellation according to the stop strategy. The embodiment of the invention also discloses a channel estimation apparatus for a TD-SCDMA system, a communication device and a computer program executing the channel estimation method.

Abstract: Embodiments of the invention relate to payload storage format for storing data in support of an aggregation function. As an input is subject to aggregation, the input is evaluated to ascertain a payload format for the aggregation. It is understood that there is more than one payload format. An evaluation of the aggregation key is a factor in the initial payload format. If the key is an addition to an existing aggregation, the evaluation considers changing the format of the payload to address processing and/or memory efficiency for the aggregation. The evaluation and the format change takes place dynamically so that the aggregation may continue.

Abstract: There are disclosed compounds that modulate the activity of inhibitors of apoptosis (IAPs), pharmaceutical compositions containing said compounds and methods of treating proliferative disorders and disorders of dysregulated apoptosis, such as cancer, utilizing the compounds of the invention.

Abstract: A method for use in processing database queries performed on a database, having tables made up of outer table data and corresponding inner table data, distributed among storage associated with multiple nodes of a multi-threaded cluster of computers is described. The method involves, on each node, constructing a Bloom filter by writing a local portion of the complete Bloom filter and then receiving and merging Bloom filter components sent from each node using different startingOffset positions and then, once the Bloom filter is complete at a node, using the complete Bloom filter as a join filter in a table join operation, without regard to Bloom filter construction occurring at other nodes.