Patents by Inventor Lisa Collins
Lisa Collins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20090209601Abstract: Disclosed herein are methods of preventing and treating osteoarthritis through the use of RXR agonists.Type: ApplicationFiled: February 11, 2009Publication date: August 20, 2009Applicant: WyethInventors: Sunil Nagpal, Zhiyong Yang, Elisabeth Morris, Edward R. Lavallie, Lisa A. Collins-Racie
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Publication number: 20090202474Abstract: Methods of screening for agents for treating inflammatory diseases are provided. The methods involve screening for agents that modulate the activity or expression of GPR64, which has been discovered herein to play a role in inflammatory diseases. Methods for treating an inflammatory disease, as well as methods of modulating the activity or expression of GPR64, methods of screening for an inflammatory disease in a subject, pharmaceutical compositions, a nucleic acid variant, and antibodies are also provided.Type: ApplicationFiled: November 19, 2008Publication date: August 13, 2009Applicant: WYETHInventors: Priya CHOCKALINGAM, Manas K. MAJUMDAR, Debra D. PITTMAN, Julia BILLIARD, Edward Roland LAVALLIE, Jeffrey L. FELDMAN, Lisa COLLINS-RACIE, Vishnuvardhan DAESETY, Robert MORAN, Elisabeth A. MORRIS, Paul YAWORSKY
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Publication number: 20090012053Abstract: Disclosed herein are methods of preventing and treating osteoarthritis through the use of LXR agonists.Type: ApplicationFiled: September 18, 2007Publication date: January 8, 2009Applicant: WyethInventors: Sunil Nagpal, Zhiyong Yang, Elisabeth Morris, Edward R. LaVallie, Lisa A. Collins-Racie
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Publication number: 20080302347Abstract: An apparatus for one-handed operation of archery equipment may facilitate drawing and firing of an arrow from a bow. The apparatus may comprise a release aid having jaws for selective engagement and disengagement of a bowstring and a trigger mechanism operable to open and close the jaws. Head gear may be configured for attachment to the head of an archer and may be coupled to the release aid with a connection mechanism such that the archer may resist a tension in the bowstring with the headgear. An alternative apparatus comprises an automatic drawbar and engagement head such that an archer may manipulate drawbar controls to draw and release an arrow from a bow.Type: ApplicationFiled: June 5, 2008Publication date: December 11, 2008Inventors: Daniel Immesberger, Lisa Collins
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Publication number: 20080139452Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.Type: ApplicationFiled: December 13, 2007Publication date: June 12, 2008Applicant: ONO PHARMACEUTICAL CO., LTD.Inventors: Kenneth Jacobs, John M. McCoy, Edward R. LaVallie, Lisa A. Collins-Racie, David Merberg, Michael J. Agostino, Robert Steininger, Vikki Spaulding, Gordon G. Wong, Hilary F. Clark, Kim Fechtel, Cheryl Evans, Maurice Treacy
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Patent number: 7344861Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.Type: GrantFiled: April 3, 2006Date of Patent: March 18, 2008Assignee: Ono Pharmaceutical Co., Ltd.Inventors: Kenneth Jacobs, John M. McCoy, Edward R. LaVallie, Lisa A. Collins-Racie, David Merberg, Michael J. Agostino, Robert J. Steininger, II, Vikki Spaulding, Gordon G. Wong, Hilary F. Clark, Kim Fechtel, Cheryl Evans, Maurice Treacy
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Publication number: 20070191268Abstract: Recombinant lubricin molecules and uses thereof Novel recombinant lubricin molecules and their uses as lubricants anti-adhesive agents and/or intra-articular supplements for, e.g., synvial joints, meniscus, tendon, peritoneum, pericardium and pleura are provided.Type: ApplicationFiled: August 13, 2004Publication date: August 16, 2007Applicant: WYETHInventors: Carl Flannery, Christopher Corcoran, Bethany Freeman, Lisa Collins-Racie
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Publication number: 20070181521Abstract: This invention is a towel that attaches onto a drinking bottle and allows a person to quickly wipe and absorb fluids off their body. It acts as a guard against spills by the person drinking. The towel is made of lightweight, soft, and absorbent materials, which may be disposable or washable. An alternative embodiment can be attached to a canteen, to provide an emergency filed dressing kit.Type: ApplicationFiled: February 3, 2006Publication date: August 9, 2007Inventor: Lisa Collins
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Publication number: 20070178574Abstract: This invention relates to aggrecanase polypeptides and aggrecanase polypeptide/ligand complexes, crystals of aggrecanase and aggrecanase polypeptide/ligand complexes, and related methods and software systems.Type: ApplicationFiled: August 24, 2006Publication date: August 2, 2007Applicant: WYETHInventors: Lydia Mosyak, Thomas Rush, Xiaotian Zhong, Thomas McDonagh, Katy Georgiadis, Phaik-Eng Sum, Edward LaVallie, Lisa Collins-Racie, Christopher Corcoran, Ravindra Kumar, Tracy Hebert, Stephane Olland, Stewart Mackie
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Publication number: 20070161046Abstract: Truncated aggrecanase proteins and nucleotides sequences encoding them as well as processes for producing them are disclosed. Additionally, aggrecanases with amino acid mutations that lead to increased stability and expression levels in comparison with wild-type or native aggrecanases are also disclosed. Aggrecanases of the invention are especially useful for development of compositions for treatment of diseases such as osteoarthritis. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.Type: ApplicationFiled: December 15, 2006Publication date: July 12, 2007Applicant: WyethInventors: Katy Georgiadis, Tara Crawford, Kathleen Tomkinson, Lisa Collins-Racie, Christopher Corcoran, Bethany Freeman, Edward LaVallie
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Publication number: 20070128616Abstract: Novel aggrecanase proteins and the nucleotide sequences encoding them as well as processes for producing them are disclosed. Methods of identifying and developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.Type: ApplicationFiled: May 22, 2006Publication date: June 7, 2007Applicant: WyethInventors: Christopher Corcoran, Michael Agostino, Edward LaVallie, Carl Flannery, Weilan Zeng, Lisa Collins-Racie, Bethany Freeman
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Patent number: 7223858Abstract: Truncated aggrecanase proteins and nucleotides sequences encoding them as well as processes for producing them are disclosed. Additionally, aggrecanases with amino acid mutations that lead to increased stability and expression levels in comparison with wild-type or native aggrecanases are also disclosed. Aggrecanases of the invention are especially useful for development of compositions for treatment of diseases such as osteoarthritis. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.Type: GrantFiled: July 18, 2006Date of Patent: May 29, 2007Assignee: WyethInventors: Katy E. Georgiadis, Tara K. Crawford, Kathleen N. Tomkinson, Lisa A. Collins-Racie, Christopher J. Corcoran, Bethany A. Freeman, Edward R. LaVallie
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Publication number: 20070105207Abstract: This invention relates to aggrecanase polypeptides and aggrecanase polypeptide/ligand complexes, crystals of aggrecanase and aggrecanase polypeptide/ligand complexes, and related methods and software systems.Type: ApplicationFiled: August 24, 2006Publication date: May 10, 2007Applicant: WYETHInventors: Lydia Mosyak, Thomas Rush, Stephane Olland, Edward LaVallie, Lisa Collins-Racie, Christopher Corcoran, Stewart Mackie
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Patent number: 7150983Abstract: Truncated aggrecanase proteins and nucleotides sequences encoding them as well as processes for producing them are disclosed. Additionally, aggrecanases with amino acid mutations that lead to increased stability and expression levels in comparison with wild-type or native aggrecanases are also disclosed. Aggrecanases of the invention are especially useful for development of compositions for treatment of diseases such as osteoarthritis. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.Type: GrantFiled: February 5, 2003Date of Patent: December 19, 2006Assignee: WyethInventors: Katy E. Georgiadis, Tara K. Crawford, Kathleen N. Tomkinson, Lisa A. Collins-Racie, Christopher J. Corcoran, Bethany A. Freeman, Edward R. Lavallie
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Publication number: 20060269957Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.Type: ApplicationFiled: July 12, 2006Publication date: November 30, 2006Applicant: Ono Pharmaceutical Co. Ltd.Inventors: Kenneth Jacobs, John McCoy, Edward LaVallie, Lisa Collins-Racie, Cheryl Evans, David Merberg, Maurice Treacy, Michael Bowman, Vikki Spaulding, McKeough Carlin-Duckett, Kerry Kelleher
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Publication number: 20060257989Abstract: Truncated aggrecanase proteins and nucleotides sequences encoding them as well as processes for producing them are disclosed. Additionally, aggrecanases with amino acid mutations that lead to increased stability and expression levels in comparison with wild-type or native aggrecanases are also disclosed. Aggrecanases of the invention are especially useful for development of compositions for treatment of diseases such as osteoarthritis. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.Type: ApplicationFiled: July 18, 2006Publication date: November 16, 2006Applicant: WyethInventors: Katy Georgiadis, Tara Crawford, Kathleen Tomkinson, Lisa Collins-Racie, Christopher Corcoran, Bethany Freeman, Edward LaVallie
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Publication number: 20060177904Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.Type: ApplicationFiled: April 3, 2006Publication date: August 10, 2006Applicant: ONO PHARMACEUTICAL CO., LTD.Inventors: Kenneth Jacobs, John McCoy, Edward LaVallie, Lisa Collins-Racie, David Merberg, Michael Agostino, Robert Steininger, Vikki Spaulding, Gordon Wong, Hilary Clark, Kim Fechtel, Cheryl Evans, Maurice Treacy
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Patent number: 7078217Abstract: Novel aggrecanase proteins and the nucleotide sequences encoding them as well as processes for producing them are disclosed. Methods of identifying and developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.Type: GrantFiled: January 31, 2003Date of Patent: July 18, 2006Assignee: WyethInventors: Christopher J. Corcoran, Michael J. Agostino, Edward R. LaVallie, Carl R. Flannery, Lisa A. Collins-Racie
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Publication number: 20060063227Abstract: Novel polynucleotides and the proteins encoded thereby are disclosed.Type: ApplicationFiled: December 14, 2004Publication date: March 23, 2006Inventors: Kenneth Jacobs, John McCoy, Edward LaVallie, Lisa Collins-Racie, Cheryl Evans, David Merberg, Maurice Treacy, Michael Bowman, Vikki Spaulding, Michael Agostino
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Publication number: 20050277175Abstract: The invention provides truncated biologically active ADAMTS polypeptides, particularly those with hyalectenase activity, and more particularly those with aggrecanase activity, that exhibit greater stability and homogeneity and higher expression yields than their full-length counterparts. The invention also provides nucleic acid molecules encoding such truncated biologically active ADAMTS polypeptides and methods for producing the truncated biologically active ADAMTS polypeptides. In addition, the invention provides methods for identifying compounds capable of modulating biologically active ADAMTS polypeptides, particularly those compounds that inhibit aggrecanase activity.Type: ApplicationFiled: April 18, 2005Publication date: December 15, 2005Applicant: WYETHInventors: Edward LaVallie, Lisa Collins-Racie, Christopher Corcoran, Natalie Twine, Michael Agostino