Abstract: The present disclosure provides an antibody-drug conjugate and use thereof. The antibody-drug conjugate has a structure represented by formula I, namely Ab-(L-D) p, wherein Ab is an anti-GPC3 antibody, L is a linker, and D is a cytotoxin. The antibody-drug conjugate of the present disclosure has good activity in inhibiting tumor cell growth in vivo and in vitro, and has relatively low cytotoxicity.

Abstract: An example method in this application is provided, which includes: receiving a first parameter sent by a first network device, where the first parameter is determined based on first configuration information, the first configuration information is used to configure a synchronization signal block (SSB) index of a second network device in at least one area, and the at least one area includes a coverage area of the second network device; calculating a measurement start time based on the first parameter, where the measurement start time indicates a time at which user equipment starts measuring a to-be-measured SSB of the second network device; and measuring, by the user equipment, the to-be-measured SSB of the second network device based on the measurement start time.

Abstract: The application provides a display panel and display device; in the display panel, by having the gate driving circuit comprise a plurality of stages of first gate driving units in a cascaded configuration and at least one stage of second gate driving unit, the first gate driving unit is configured to output a scanning signal, the second gate driving unit is configured to output a stage transmission signal to a corresponding one or more first gate driving units. In a direction perpendicular to the arrangement direction of each of the stages of the first gate driving units, a width of the second gate driving unit is less than a width of the corresponding one or more of first gate driving units.

Abstract: A communication method and a related apparatus, where the method includes: receiving first indication information, where the first indication information indicates an index of a first geographical area to which first location information belongs, and the first location information is location information of a terminal device; and determining a first paging occasion (PO) based on the index of the first geographical area. The first geographical area is smaller than a spatial coverage area of a synchronization signal block (SSB) beam.

Abstract: Uplink interference measurement methods, devices, and systems are provided. An example network device sends first information to a terminal device. The first information indicates at least one time-frequency resource. I time-frequency resources in the at least one time-frequency resource occupy M consecutive slots in time domain and occupy N consecutive RBs in frequency domain and each of the I time-frequency resources includes K measurement resource blocks, K?M*N. Each measurement resource block occupies one slot in time domain and occupies one RB in frequency domain. A quantity of REs for uplink interference measurement in each measurement resource block is less than a total quantity of REs included in each measurement resource block. The network device measures an uplink interference signal on the resource element for uplink interference measurement in each measurement resource block.

Abstract: A communication method and a communication apparatus. A network device determines first configuration information, where the first configuration information is used to configure, after a terminal device camps on a target cell through a cell reselection process and before the terminal device retrieves a system information block SIB1 message of the target cell, a configuration parameter of paging and/or a configuration parameter of random access of the terminal device in the target cell; the network device sends the first configuration information to the terminal device; after the terminal device camps on the target cell through the cell reselection process and before the terminal device retrieves the system information block SIB1 message of the target cell, based on the first configuration information, the terminal device receives paging of the terminal device in the target cell and/or initiates random access of the terminal device in the target cell.

Abstract: An artificial valve and a valve delivery system are provided. The artificial valve includes a top stent, a middle stent and a bottom stent. The top stent, the middle stent and the bottom stent are connected in sequence; the top stent is circumferentially provided with at least three locking stents; each locking stent has a locking end at the top; the middle stent is provided with at least three valve leaflet fixing parts; in the unlocked state of each locking end, the diameter of the circumference where the uppermost edges of the three valve leaflet fixing parts are located is ?1, and in the locked state of each locking end, the diameter of the circumference where the uppermost edges of the three valve leaflet fixing parts are located is ?2, which is larger than or equal to 74% of ?1.

Abstract: Provided herein are lipid nanoparticles comprising cationic steroid compound, as well as the preparation and uses of such lipid nanoparticles. Such lipid nanoparticles are useful in the delivery of payloads, such as nucleic acids, in vivo to non-hepatic organs (e.g., lung) for the treatment or prevention of certain diseases or disorders, particularly lung diseases.

Abstract: Methods provided herein may include illuminating a region on a wafer within a semiconductor processing tool, the wafer having a layer of a material that is at least semi-transparent to light and has a measurable extinction coefficient, and the region being a first fraction of the wafer's surface, detecting light reflected off the material and off a surface underneath the material using one or more detectors and generating optical data corresponding to the detected light, generating a metric associated with a property of the material on the wafer by applying the optical data to a transfer function that relates the optical data to the metric associated with the property of the material on the wafer, determining an adjustment to one or more processing parameters for a processing module, and performing or modifying a processing operation in the processing module according to the adjusted one or more processing parameters.

Abstract: A example method provided in this application includes: receiving first ephemeris information of a serving satellite sent by a network device, where the first ephemeris information includes first indication information, and the first indication information is used to indicate a threshold for an coverage edge footprint of the serving satellite; and determining, based on the first ephemeris information, whether to start obtaining other system information (OSI) broadcast by the network device at the coverage edge footprint, where the OSI is related to mobility management.

Abstract: A terminal receives resource configuration information and first information from a first satellite, where the resource configuration information is used to configure an uplink resource, and the first information is used to determine whether the terminal is located within a first area. When the terminal enters a coverage area of a second satellite, it may send an RRC request to the second satellite through the uplink resource if the terminal is located within the first area. According to the method, the terminal can send, based on the uplink resource configured by the resource configuration information, an RRC request to the second satellite immediately when it enters the coverage area of the second satellite.

Abstract: In this disclosure, methods are provided. In an example method, system information and a synchronization sequence are sent in a same information block for a terminal device initiating random access, where the system information comprises position information of a network device and random access configuration information.

Abstract: The purpose is to determine a more accurate region of interest. An image processing system 1 comprises a landmark detector that detects, in a joint image which is an in vivo image of a human joint, two or more joint landmarks, each of which is a landmark for the joint, and a ROI1 determinator that determines, in the joint image, a region of interest for the joint based on the two or more joint landmarks detected. The landmark detector may perform detection using a landmark detection model which, upon input of the joint image, detects two or more joint landmarks in the joint image. The landmark detection model may be a model trained based on training data comprising a pair of a joint image and an image in which two or more joint landmarks in the joint image are annotated.

Abstract: The anti-PTK7 (protein tyrosine kinase 7) antibodies, antigen-binding fragments thereof, and antibody-drug conjugate (ADC) derived therefrom; anti-TROP2 (trophoblast cell surface antigen 2) antibodies, antigen-binding fragments thereof, and antibody-drug conjugate (ADC) derived therefrom; and anti-PTK7/TROP2 (e. g., multispecific or bispecific) antibodies or antigen-binding fragments thereof, and antibody-drug conjugate (ADC) derived therefrom and uses thereof are disclosed.

Abstract: A communication method includes receiving first information indicating whether a region or a beam in a cell allows access or camping; and determining, based on the first information, whether to access or camp on the cell.

Abstract: Provided are an interleukin 29 (IL29) mutant protein, and a fusion protein, a conjugate, a pharmaceutical composition, a product and a kit which comprises the mutant protein. The provided IL29 mutant protein has good activity and stability, and can effectively prevent and/or treat viral infectious diseases, tumors and other diseases needing to regulate the body immune function.

Abstract: A spectrum resource determining method, apparatus, and system, and a storage medium are provided. A server configures at least one of a first spectrum resource, a second spectrum resource that corresponds to a first network and that is in the first spectrum resource, a third spectrum resource that corresponds to a second network and that is in the first spectrum resource, a spectrum boundary between the second spectrum resource and the third spectrum resource, a minimum Doppler shift, and a maximum Doppler shift, so that the second network can accurately determine, based on the configuration, a spectrum boundary corresponding to the second network. In this way, a guard band is configured, so that spectrum overlapping caused by a Doppler shift can be avoided, thereby avoiding interference between the first network and the second network.

Abstract: A communication method, an apparatus, a system, a chip, a chip module, and a storage medium are provided. A network device, such as a satellite base station, pairs a plurality of terminals based on weight vectors corresponding to main transmission directions of the plurality of terminals, configures a matrix of a group of shared reference signal weights for the paired terminals, and transmits a reference signal to the paired terminals on a reference signal port group at a plurality of time instances based on the reference signal weight matrix.

Abstract: A locking spring piece for use with a sliding rail includes a connection hole having an inner wall, and a first toothed portion disposed at the inner wall of the connection hole, the first toothed portion comprising at least one tooth, and the at least one tooth of the first toothed portion protruding from the inner wall of the connection hole. The connection hole is configured to allow a connecting member of the sliding rail to pass through, and enable the connecting member to abut against the first toothed portion.

Abstract: A communication method and apparatus are provided. The method includes: A terminal device receives from a network device configuration information of a time-frequency resource, the configuration information includes configuration information of a first time-frequency resource and configuration information of a second time-frequency resource. The first time-frequency resource is used for an interference measurement for a first geographic coverage area, the second time-frequency resource is used for an interference measurement for a second geographic coverage area, and the second geographic coverage area is a part of the first geographic coverage area. The terminal device performs an interference measurement based on the configuration information of the time-frequency resource. According to the method, interference measurement can be effectively implemented, to resolve interference problem in communications, and overheads of resources occupied during an interference measurement can be reduced.