Patents by Inventor Liuqing Yang

Liuqing Yang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210101984
    Abstract: A B7-H3 antibody, an antigen-binding fragment thereof and a medical use thereof are provided. Furthermore, a pharmaceutical composition containing the B7-H3 antibody or antigen-binding fragment thereof, and the use thereof as a medicament are provided. In particular, a use of a human B7-H3 antibody or antigen-binding fragment thereof for the manufacture of a medicament for the treatment of a B7-H3-associated disease or condition are described.
    Type: Application
    Filed: December 15, 2020
    Publication date: April 8, 2021
    Inventors: Jinming GU, Xiaohua WANG, Xin YE, Liuqing YANG, Ting ZHANG, Weikang TAO, Lianshan ZHANG
  • Patent number: 10899837
    Abstract: A B7-H3 antibody, an antigen-binding fragment thereof and a medical use thereof are provided. Furthermore, a pharmaceutical composition containing the B7-H3 antibody or antigen-binding fragment thereof, and the use thereof as a medicament are provided. In particular, a use of a human B7-H3 antibody or antigen-binding fragment thereof for the manufacture of a medicament for the treatment of a B7-H3-associated disease or condition are described.
    Type: Grant
    Filed: March 30, 2018
    Date of Patent: January 26, 2021
    Assignees: Jiangsu Hengrui Medicine Co., Ltd., Shanghai Hengrui Pharmaceutical Co., Ltd.
    Inventors: Jinming Gu, Xiaohua Wang, Xin Ye, Liuqing Yang, Ting Zhang, Weikang Tao, Lianshan Zhang
  • Publication number: 20200378825
    Abstract: A transfer impedance calibration device for transducers based on spatial frequency domain smoothing technology is provided. The calibration device comprises a signal transmitter, a power amplifier, a transducer pair, a measurement amplifier, a signal collector, a measurement processor and a current sampler. The device extracts acoustic channel information through the sound filed spatial information or measurement method to design a spatial domain smoothing filter, and then comprehensively processes the transmitted current signal and the received signal through the spatial frequency domain smoothing technology to obtain the transfer impedance of the transducer pair.
    Type: Application
    Filed: April 29, 2020
    Publication date: December 3, 2020
    Inventors: Yi CHEN, Liuqing YANG, Xiaofeng JIN, Guanghui JIA, Han ZHAO
  • Publication number: 20200355843
    Abstract: A method of free-field broadband calibration of hydrophone sensitivity based on pink noise, relating to the field of free-field underwater acoustic measurement, and is mainly used for broadband measurements of hydrophone sensitivity in free-field. The method of the present disclosure is to transmit a broadband pink noise signal by controlling the signal source, and to perform the synchronous processing and FFT to the transmitted current signal and the received voltage signal, such as interception and zero padding, and finally obtain the transfer function in the frequency domain; by analyzing the direct wave and the reflected wave in the water tank, the transfer function is averaged by a rectangular window to eliminate the influence of the reverberation of the reflected wave in the water tank, so as to obtain the broadband transfer function of the free-field between the transmitting transducer and the hydrophone.
    Type: Application
    Filed: April 29, 2020
    Publication date: November 12, 2020
    Inventors: Yi CHEN, Guanghui JIA, Xiaofeng JIN, Liuqing YANG, Han ZHAO
  • Patent number: 10811185
    Abstract: The subject disclosure provides for utilizing pulse width modulation (PWM) signaling to influence a closed loop of a shunt boost controller and reduce an imbalance of a load. The imbalance reduction helps reduce remanence of a current transformer (CT) and thereby prevent saturation of the CT. A shunt boost controller provides the control signal to control flow of current to the load. A feedback network provides a feedback signal to the shunt boost controller based on a direct current (DC) voltage and causes a power switch circuit to turn on when a magnitude of the feedback signal exceeds a threshold magnitude. The PWM generator supplies a PWM signal to cause the control signal to be provided more symmetrical to the power switch circuit and causes the power switch circuit to turn on more frequently with the control signal to reduce the imbalance of the load.
    Type: Grant
    Filed: September 13, 2018
    Date of Patent: October 20, 2020
    Assignee: Analog Devices Global Unlimited Company
    Inventors: Liuqing Yang, Jian Ye, Zhijie Zhu
  • Publication number: 20200165345
    Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.
    Type: Application
    Filed: November 15, 2016
    Publication date: May 28, 2020
    Inventors: Tejinder Kaur BHINDER, Chong DING, Xu FENG, Wenqing JIANG, Alan Peter LEWIS, Yingli MA, Guhan NAGAPPAN, Radha Shah PARMAR, Yangsheng QIU, Liuqing YANG, Qing ZHANG, Yanjiao ZHOU
  • Publication number: 20200090861
    Abstract: The subject disclosure provides for utilizing pulse width modulation (PWM) signaling to influence a closed loop of a shunt boost controller and reduce an imbalance of a load. The imbalance reduction helps reduce remanence of a current transformer (CT) and thereby prevent saturation of the CT. A shunt boost controller provides the control signal to control flow of current to the load. A feedback network provides a feedback signal to the shunt boost controller based on a direct current (DC) voltage and causes a power switch circuit to turn on when a magnitude of the feedback signal exceeds a threshold magnitude. The PWM generator supplies a PWM signal to cause the control signal to be provided more symmetrical to the power switch circuit and causes the power switch circuit to turn on more frequently with the control signal to reduce the imbalance of the load.
    Type: Application
    Filed: September 13, 2018
    Publication date: March 19, 2020
    Inventors: Liuqing YANG, Jian YE, Zhijie ZHU
  • Publication number: 20200031934
    Abstract: A B7-H3 antibody, an antigen-binding fragment thereof and a medical use thereof are provided. Furthermore, a pharmaceutical composition containing the B7-H3 antibody or antigen-binding fragment thereof, and the use thereof as a medicament are provided. In particular, a use of a human B7-H3 antibody or antigen-binding fragment thereof for the manufacture of a medicament for the treatment of a B7-H3-associated disease or condition are described.
    Type: Application
    Filed: March 30, 2018
    Publication date: January 30, 2020
    Inventors: Jinming GU, Xiaohua WANG, Xin YE, Liuqing YANG, Ting ZHANG, Weikang TAO, Lianshan ZHANG
  • Patent number: 10420787
    Abstract: Disclosed are a crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form, and a preparation method and a use thereof. In an X-ray powder diffraction pattern using Cu-K? as a source of radiation, the crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form has characteristic peaks at positions where diffraction angles 2? are equal to 12.3°±0.2°, 17.6°±0.2°, 21.4°±0.2°, 24.7°±0.2°, 25.3°±0.2° and 27.8°±0.2°. The crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form of the present invention has a high purity, and good stability; the preparation method is simple and convenient, has good reproducibility, and is easy to industrially popularize and apply.
    Type: Grant
    Filed: March 5, 2015
    Date of Patent: September 24, 2019
    Assignees: SPH NO.1 BIOCHEMICAL & PHARMACEUTICAL CO., LTD., SHANGHAI ZIYUAN PHARMACEUTICAL CO., LTD.
    Inventors: Zhenhui Huang, Liuqing Yang, Jianli Huo, Xinlei Zhu, Jinguo Ding, Zhigang Zhang
  • Patent number: 9914781
    Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.
    Type: Grant
    Filed: November 15, 2016
    Date of Patent: March 13, 2018
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED
    Inventors: Tejinder Kaur Bhinder, Chong Ding, Xu Feng, Wenqing Jiang, Alan Peter Lewis, Yingli Ma, Guhan Nagappan, Radha Shah Parmar, Yangsheng Qiu, Liuqing Yang, Qing Zhang, Yanjiao Zhou
  • Publication number: 20180050057
    Abstract: Disclosed are a crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form, and a preparation method and a use thereof. In an X-ray powder diffraction pattern using Cu-K? as a source of radiation, the crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form has characteristic peaks at positions where diffraction angles 2? are equal to 12.3°±0.2°, 17.6°±0.2°, 21.4°±0.2°, 24.7°±0.2°, 25.3°±0.2° and 27.8°±0.2°. The crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form of the present invention has a high purity, and good stability; the preparation method is simple and convenient, has good reproducibility, and is easy to industrially popularize and apply.
    Type: Application
    Filed: March 5, 2015
    Publication date: February 22, 2018
    Inventors: Zhenhui HUANG, Liuqing YANG, Jianli HUO, Xinlei ZHU, Jinguo DING, Zhigang ZHANG
  • Patent number: 9866136
    Abstract: A power converter can include an electrical isolation circuit between input and output nodes. An input signal monitor node can be provided, such as on a converter output side of the isolation circuit. In an example, a peak detection circuit can be coupled to the input signal monitor node. The output node of the power converter can be configured to supply an output power signal that is a function of an input signal at the input node. The power converter can include multiple, independently-switchable switches at one or more of the input and output sides of the isolation circuit. In an example, the power converter with the input signal monitor node can be configured as a bias supply to provide power, at the output node, to a controller circuit for a main stage power converter circuit.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: January 9, 2018
    Assignee: Analog Devices Global
    Inventors: Jun Duan, Liuqing Yang, Xudong Huang, Zhijie Zhu, Renjian Xie
  • Patent number: 9523256
    Abstract: A fold back ring for a swell packer is disclosed. A swell packer has a support member, a swellable element coupled to the support member, and a fold back ring coupled to the support member and engaging the swellable element. The fold back ring is sized and positioned such that when the swellable element swells, the fold back ring flexes outwardly and is caught between the swellable element and the interior surface of the well. The fold back ring therefore forms a barrier against extrusion of the swellable element.
    Type: Grant
    Filed: December 4, 2013
    Date of Patent: December 20, 2016
    Assignee: SCHLUMBERGER TECHNOLOGY CORPORATION
    Inventors: Erik Bilansky, Jeff Maynard, Liuqing Yang
  • Publication number: 20160175432
    Abstract: The present invention discloses an oil-in-water emulsion containing no surfactant, which comprises a metabolizable oil phase, an aqueous phase and oil-water amphipathic solid particles dispersed in the aqueous phase and having biocompatibility, wherein the oil phase comprises squalene or/and tocol; the aqueous phase is any one selected from the group consisting of purified water, water for injection, glycerine aqueous solution, buffering salts aqueous solution or clinically usable transfusion, or the combination of at least two selected therefrom; the solid particles have an average particle size in a scale of from nanometer to micrometer. The emulsion of the present invention can be used as vaccine adjuvant, drug delivery carrier or sustained/controlled-release carrier, and have the controllable properties. The resultant emulsion is stable, avoids the use of surfactants and can reduce the human poisoning and environmental pollution.
    Type: Application
    Filed: November 26, 2014
    Publication date: June 23, 2016
    Applicant: Institute of Process Engineering, Chinese Academy of Sciences
    Inventors: Guanghui MA, Jie WU, Liuqing YANG, Yufei XIA, Feng QI, Qingze FAN
  • Patent number: 9243473
    Abstract: A packer that is usable with a well includes a tubular inner core and a swellable body that is mounted to the core and is adapted to swell in the presence of a triggering agent to form an annular seal in the well. The swellable body longitudinally extends between first and second ends of the body and includes a first region that is located between the first and second ends of the swellable body to swell at a first rate and at least a second region that is located closer to one of the first and second ends than the first region to swell at a second rate less than the first rate.
    Type: Grant
    Filed: July 10, 2012
    Date of Patent: January 26, 2016
    Assignee: Schlumberger Technology Corporation
    Inventors: Liuqing Yang, Xiaohong Ren, Camilla Werningsen
  • Publication number: 20150308214
    Abstract: A fold back ring for a swell packer is disclosed. A swell packer has a support member, a swellable element coupled to the support member, and a fold back ring coupled to the support member and engaging the swellable element. The fold back ring is sized and positioned such that when the swellable element swells, the fold back ring flexes outwardly and is caught between the swellable element and the interior surface of the well. The fold back ring therefore forms a barrier against extrusion of the swellable element.
    Type: Application
    Filed: December 4, 2013
    Publication date: October 29, 2015
    Applicant: Schlumberger Technology Corporation
    Inventors: Erik Bilansky, Jeff Maynard, Liuqing Yang
  • Publication number: 20150162837
    Abstract: A power converter can include an electrical isolation circuit between input and output nodes. An input signal monitor node can be provided, such as on a converter output side of the isolation circuit. In an example, a peak detection circuit can be coupled to the input signal monitor node. The output node of the power converter can be configured to supply an output power signal that is a function of an input signal at the input node. The power converter can include multiple, independently-switchable switches at one or more of the input and output sides of the isolation circuit. In an example, the power converter with the input signal monitor node can be configured as a bias supply to provide power, at the output node, to a controller circuit for a main stage power converter circuit.
    Type: Application
    Filed: December 9, 2013
    Publication date: June 11, 2015
    Applicant: Analog Devices Technology
    Inventors: Jun Duan, Liuqing Yang, Xudong Huang, Zhijie Zhu, Renjian Xie
  • Publication number: 20140014374
    Abstract: A packer that is usable with a well includes a tubular inner core and a swellable body that is mounted to the core and is adapted to swell in the presence of a triggering agent to form an annular seal in the well. The swellable body longitudinally extends between first and second ends of the body and includes a first region that is located between the first and second ends of the swellable body to swell at a first rate and at least a second region that is located closer to one of the first and second ends than the first region to swell at a second rate less than the first rate.
    Type: Application
    Filed: July 10, 2012
    Publication date: January 16, 2014
    Inventors: Liuqing Yang, Xiaohong Ren, Camilla Werningsen
  • Patent number: 8627401
    Abstract: Embodiments of a white space identifier are provided. According to one embodiment, the active channel information of a cable TV can be obtained through receiving and decoding a channel changing operation command from a remote control. The active channel information can then be transmitted to white space devices located within an interference range using a wireless transmitter. The wireless transmitter can be set to utilize a narrow fixed bandwidth.
    Type: Grant
    Filed: April 2, 2010
    Date of Patent: January 7, 2014
    Assignee: University of Florida Research Foundation, Incorporated
    Inventor: Liuqing Yang
  • Publication number: 20120017256
    Abstract: Embodiments of a white space identifier are provided. According to one embodiment, the active channel information of a cable TV can be obtained through receiving and decoding a channel changing operation command from a remote control. The active channel information can then be transmitted to white space devices located within an interference range using a wireless transmitter. The wireless transmitter can be set to utilize a narrow fixed bandwidth.
    Type: Application
    Filed: April 2, 2010
    Publication date: January 19, 2012
    Inventor: Liuqing Yang