Abstract: Disclosed are a crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form, and a preparation method and a use thereof. In an X-ray powder diffraction pattern using Cu-K? as a source of radiation, the crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form has characteristic peaks at positions where diffraction angles 2? are equal to 12.3°±0.2°, 17.6°±0.2°, 21.4°±0.2°, 24.7°±0.2°, 25.3°±0.2° and 27.8°±0.2°. The crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form of the present invention has a high purity, and good stability; the preparation method is simple and convenient, has good reproducibility, and is easy to industrially popularize and apply.

Abstract: The present invention relates to TrkB binding agonists, and to the use of such agonists in the treatment of neurological disorders and other disorders. The present invention also relates to specific TrkB binding agonists comprising CDRs, variable regions, heavy and light chains, and variant sequences thereof.

Abstract: Disclosed are a crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form, and a preparation method and a use thereof. In an X-ray powder diffraction pattern using Cu-K? as a source of radiation, the crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form has characteristic peaks at positions where diffraction angles 2? are equal to 12.3°±0.2°, 17.6°±0.2°, 21.4°±0.2°, 24.7°±0.2°, 25.3°±0.2° and 27.8°±0.2°. The crystallization water-free calcium dibutyryladenosine cyclophosphate crystal form of the present invention has a high purity, and good stability; the preparation method is simple and convenient, has good reproducibility, and is easy to industrially popularize and apply.

Abstract: A power converter can include an electrical isolation circuit between input and output nodes. An input signal monitor node can be provided, such as on a converter output side of the isolation circuit. In an example, a peak detection circuit can be coupled to the input signal monitor node. The output node of the power converter can be configured to supply an output power signal that is a function of an input signal at the input node. The power converter can include multiple, independently-switchable switches at one or more of the input and output sides of the isolation circuit. In an example, the power converter with the input signal monitor node can be configured as a bias supply to provide power, at the output node, to a controller circuit for a main stage power converter circuit.

Abstract: A fold back ring for a swell packer is disclosed. A swell packer has a support member, a swellable element coupled to the support member, and a fold back ring coupled to the support member and engaging the swellable element. The fold back ring is sized and positioned such that when the swellable element swells, the fold back ring flexes outwardly and is caught between the swellable element and the interior surface of the well. The fold back ring therefore forms a barrier against extrusion of the swellable element.

Abstract: The present invention discloses an oil-in-water emulsion containing no surfactant, which comprises a metabolizable oil phase, an aqueous phase and oil-water amphipathic solid particles dispersed in the aqueous phase and having biocompatibility, wherein the oil phase comprises squalene or/and tocol; the aqueous phase is any one selected from the group consisting of purified water, water for injection, glycerine aqueous solution, buffering salts aqueous solution or clinically usable transfusion, or the combination of at least two selected therefrom; the solid particles have an average particle size in a scale of from nanometer to micrometer. The emulsion of the present invention can be used as vaccine adjuvant, drug delivery carrier or sustained/controlled-release carrier, and have the controllable properties. The resultant emulsion is stable, avoids the use of surfactants and can reduce the human poisoning and environmental pollution.

Abstract: A packer that is usable with a well includes a tubular inner core and a swellable body that is mounted to the core and is adapted to swell in the presence of a triggering agent to form an annular seal in the well. The swellable body longitudinally extends between first and second ends of the body and includes a first region that is located between the first and second ends of the swellable body to swell at a first rate and at least a second region that is located closer to one of the first and second ends than the first region to swell at a second rate less than the first rate.

Abstract: A fold back ring for a swell packer is disclosed. A swell packer has a support member, a swellable element coupled to the support member, and a fold back ring coupled to the support member and engaging the swellable element. The fold back ring is sized and positioned such that when the swellable element swells, the fold back ring flexes outwardly and is caught between the swellable element and the interior surface of the well. The fold back ring therefore forms a barrier against extrusion of the swellable element.

Abstract: A power converter can include an electrical isolation circuit between input and output nodes. An input signal monitor node can be provided, such as on a converter output side of the isolation circuit. In an example, a peak detection circuit can be coupled to the input signal monitor node. The output node of the power converter can be configured to supply an output power signal that is a function of an input signal at the input node. The power converter can include multiple, independently-switchable switches at one or more of the input and output sides of the isolation circuit. In an example, the power converter with the input signal monitor node can be configured as a bias supply to provide power, at the output node, to a controller circuit for a main stage power converter circuit.

Abstract: A packer that is usable with a well includes a tubular inner core and a swellable body that is mounted to the core and is adapted to swell in the presence of a triggering agent to form an annular seal in the well. The swellable body longitudinally extends between first and second ends of the body and includes a first region that is located between the first and second ends of the swellable body to swell at a first rate and at least a second region that is located closer to one of the first and second ends than the first region to swell at a second rate less than the first rate.

Abstract: Embodiments of a white space identifier are provided. According to one embodiment, the active channel information of a cable TV can be obtained through receiving and decoding a channel changing operation command from a remote control. The active channel information can then be transmitted to white space devices located within an interference range using a wireless transmitter. The wireless transmitter can be set to utilize a narrow fixed bandwidth.

Abstract: Embodiments of a white space identifier are provided. According to one embodiment, the active channel information of a cable TV can be obtained through receiving and decoding a channel changing operation command from a remote control. The active channel information can then be transmitted to white space devices located within an interference range using a wireless transmitter. The wireless transmitter can be set to utilize a narrow fixed bandwidth.

Abstract: Techniques are described that provide noncoherent demodulation via correlating “dirty” templates in wireless communication systems. In particular, the described techniques cross-correlate dirty templates that are adjacent symbol-long segments of the received noisy waveform. Unlike transmitted reference (TR) and differential templates that are noisy, i.e., propagate through the wireless communication channel, these dirty templates are both noisy and offset in time and, thus, are dirty. As a result, the described techniques enable noncoherent demodulation without timing synchronization and channel estimation. Symbol demodulation may be performed utilizing a maximum likelihood (ML) sequence detector or, alternatively, conditional ML demodulation may be performed to reduce receiver complexity. The described techniques may also be applied to a TR scheme to improve performance in the presence of mistiming.

Abstract: The invention provides an ultra-wideband (UWB) transmitter and various techniques for generating digitally filtered UWB pulses that substantially maximize power and bandwidth in one or more frequency bands while allowing narrow-band interference (NBI) to be avoided, e.g. interference to and from wireless local area networks (WLANs). In particular, the UWB transmitter utilizes a digital filter to generate digitally filtered UWB pulses to substantially maximize power and bandwidth in the Federal Communications Commission (FCC) spectral mask for UWB communications. In one embodiment, the invention provides a method comprising generating digitally filtered ultra-wide band (UWB) pulses to substantially maximize power in one or more frequency bands of a UWB spectrum and to substantially reduce power in one or more NBI frequency bands of the UWB spectrum. The invention may be implemented without modifying the analog components of existing UWB transmitters.

Abstract: Techniques are described for generating digital carrier multi-band user codes for a baseband ultra-wideband (UWB) signal. The digital carrier multi-band user codes comprise spreading codes that enable multiple access in a UWB system. The user codes are digital, lead to baseband operation, and provide flexibility in handling narrow band interference (NBI) within the UWB system. In one embodiment, the invention provides a method comprising generating digital carrier multi-band user codes for a baseband ultra-wideband (UWB) signal of a user in an UWB system.

Abstract: Techniques are described for maintaining the orthogonality of waveforms transmitted in ultra wideband (UWB) multi-user wireless communication systems. The multi-stage block-spreading (MS-BS) techniques described herein deterministically eliminate multiple user interference (MUI) in the presence of frequency-selective fading channels. A transmitter includes a block-spreading unit to generate a stream of frames from a block of information bearing symbols by applying an orthogonal set of spreading codes, such as direct sequence cod& division multiple access (CDMA) codes or digital carrier frequency multiple access codes, such that the frames corresponding to different blocks of the symbols are interleaved. The transmitter further includes a time-hopping spreading unit to generate a stream of chips from the stream of frames by applying an orthogonal set of time-hopping (TH) spreading codes such that chips corresponding to different frames are interleaved.

Abstract: Techniques are described for synchronizing the timing of the receiver with the received waveform in ultra wideband (UWB) communication systems. The described techniques correlate the received waveform with dirty templates, i.e. segments of the received waveform, with the received waveform to estimate the timing offset. The described techniques include receiving an ultra wideband (UWB) waveform through a wireless communication channel, wherein the received UWB waveform comprises bursts of information-bearing symbols. A template is selected to be used for estimating the timing offset of a burst of the received UWB waveform, wherein the template comprises a segment of a burst of the received UWB waveform, and the template is correlated with a segment of a burst of the received waveform so as to form an estimate of the timing offset of the received UWB waveform. A stream of symbol estimates is output in accordance with the estimated timing offset.

Abstract: Space-time (ST) coding techniques are described for multi-antenna transmissions in ultra-wideband (UWB) communication systems. The ST coding schemes may, therefore, be tailored for dense multipath channels. The techniques may be applied with linear and nonlinear modulation, coherent and noncoherent reception, and block interleaving of symbols. An UWB communication system is described that includes an ST encoder at the transmitter, multiple transmit and receive antennas, and two-step maximum ratio combining (MRC) at the receiver. The two-step MRC enables the receiver to collect full spatial and multipath diversity from a transmission. Two coding schemes for an UWB system with two transmit antennas and one receive antenna are described. Multiple antenna transmissions of ST encoded symbols increase the amount of diversity a receiver is able to collect without increasing the complexity of the receiver.

Abstract: Techniques are described that provide noncoherent demodulation via correlating “dirty” templates in wireless communication systems. In particular, the described techniques cross-correlate dirty templates that are adjacent symbol-long segments of the received noisy waveform. Unlike transmitted reference (TR) and differential templates that are noisy, i.e., propagate through the wireless communication channel, these dirty templates are both noisy and offset in time and, thus, are dirty. As a result, the described techniques enable noncoherent demodulation without timing synchronization and channel estimation. Symbol demodulation may be performed utilizing a maximum likelihood (ML) sequence detector or, alternatively, conditional ML demodulation may be performed to reduce receiver complexity. The described techniques may also be applied to a TR scheme to improve performance in the presence of mistiming.

Abstract: The invention provides an ultra-wideband (UWB) transmitter and various techniques for generating digitally filtered UWB pulses that substantially maximize power and bandwidth in one or more frequency bands while allowing narrow-band interference (NBI) to be avoided, e.g. interference to and from wireless local area networks (WLANs). In particular, the UWB transmitter utilizes a digital filter to generate digitally filtered UWB pulses to substantially maximize power and bandwidth in the Federal Communications Commission (FCC) spectral mask for UWB communications. In one embodiment, the invention provides a method comprising generating digitally filtered ultra-wide band (UWB) pulses to substantially maximize power in one or more frequency bands of a UWB spectrum and to substantially reduce power in one or more NBI frequency bands of the UWB spectrum. The invention may be implemented without modifying the analog components of existing UWB transmitters.