Abstract: A charge/discharge test apparatus includes a temperature control box having a test chamber provided inside and provided with an opening communicated with the test chamber and configured for extraction or insertion of a battery, and a rack connected to the temperature control box. The rack and the opening are located at different sides of the temperature control box, and the rack has an accommodating cavity inside. The charge/discharge test apparatus further includes a charge/discharge module located in the accommodating cavity and configured to charge/discharge a battery in the corresponding test chamber.

Abstract: The present disclosure belongs to the technical field of wastewater treatment, and discloses an electrochemical nitrogen and phosphorus removal device and a method.

Abstract: Provided is a fusion protein dimer using an antibody Fc region as the backbone, comprising a first and a second polypeptide chain. The first polypeptide chain comprises a first antibody Fc region and one or more single-domain antibodies fused to the first antibody Fc region. The second polypeptide chain comprises a second antibody Fc region and one or more single domain antibodies fused to the second antibody Fc region. The first polypeptide chain and/or the second polypeptide chain further comprise a cytokine fused to the Fc region of the respective antibody. Further provided is use of the fusion protein dimer in preparing an immunotherapeutic drug for treating tumors. The Fc fusion protein heterodimer not only increases the activity of a single domain antibody, but also significantly improves the biological activity of a cytokine.

Abstract: The present application provides spirocyclic lactam compounds that modulate the activity of the V617F variant of JAK2, which are useful in the treatment of various diseases, including cancer.

Abstract: An application of a prokaryotic Argonaute protein with only a cleavage activity of a target ribonucleic acid (RNA) in RNA editing is provided. The Argonaute protein is derived from a mesophilic prokaryotes Verrucomimicrobia bacterium, and its amino acid sequence is shown in SEQ ID NO: 1 or a protein with high similarity to SEQ ID NO: 1 and the same function. This protein has binding activity to a single-stranded guide DNA and nuclease activity only to the target RNA complementarily paired with the single-stranded guide DNA. Therefore, the protein can be utilized for in vitro and in vivo targeted RNA editing, providing a new powerful tool for RNA editing.

Abstract: Provided by the present application are a method and a device for constructing integrated space-terrestrial network, the method including: obtaining a target constellation and standardizing a relative motion between each target satellite in the target constellation and earth's surface according to a principle of making a satellite running in a recursive earth-repeat orbit have fixed satellite subpoint trajectories; obtaining a recursively extended topological structure according to the target constellation; according to the extended topological structure, dividing geographical cells and obtaining a mapping relationship between the geographical cells and the satellite subpoint trajectories to facilitate network addressing and networking management based on geographical location; and performing, based on a deployment rule, a recursive incremental deployment according to the extended satellite network topological structure, and realizing integrated space-terrestrial network.

Abstract: Systems, computing platforms, and methods for sampling and analyzing common mode noise on electrocardiogram signals to help to minimize the interference to the electrocardiogram signals are disclosed. Exemplary implementations may: obtain electrocardiogram signals from one or more sensors configured to be attached to a patient and communicatively connected to a patient monitor; receive the electrocardiogram signals from one or more sensors by the patient monitor; display the electrocardiogram signals on one or more displays of the patient monitor; sample and analyze a direct current range and an alternating current spectrum to identify common mode interference levels within the obtained electrocardiogram signals; display the direct current range and the alternating current spectrum via the one or more displays of the patient monitor; and update the display of the direct current range and the alternating current spectrum in real time to identify sources of common mode interference.

Abstract: A fully automated towing, alignment and hangar system suitable for an offshore operation helicopter includes a quick mooring device, a wide-angle camera installed on a rear wall of the quick mooring device, a longitudinal towing device, a DSP control unit, an MCU control unit, a helicopter and a mooring bar thereof. An alignment method based on above system includes following steps of acquiring an attitude image of a steering wheel, calculating a helicopter yaw angle and a steering wheel deflection angle, calculating position coordinates of the steering wheel, a first wheel and a second wheel in a deck coordinate system, judging boundaries relative to a towing indication line, extracting an optimal path suitable for the movement of the helicopter, calculating lateral and longitudinal movement position control commands, driving the movement of the helicopter, and repeating the above operations until the automated towing, alignment and hangar are completed.

Abstract: A patient monitoring system includes a patient monitor and an ECG lead set coupled thereto. The patient monitor may be programmed to periodically issue interrogation signals to the ECG lead set to determine the type and connection status of the ECG lead set. The interrogation signals may be issued via a communication bus. The patient monitor may time the issuance of interrogation signals to the ECG lead set to correspond to non-critical ECG intervals, such that interference with the ECG signals by the communication bus is minimized.

Abstract: The present invention belongs to the technical field of nanomedicine, and relates to a method for preparing a therapeutic protein-loaded nanoparticle, as well as a therapeutic protein-loaded nanoparticle, a suspension and a pharmaceutical composition comprising the nanoparticle, and a pharmaceutical preparation comprising the nanoparticle, the suspension or the pharmaceutical composition. The present invention further relates to a use of the nanoparticle in manufacture of a pharmaceutical composition, wherein the pharmaceutical composition is useful in prevention or treatment of a disease that can be prevented or treated by the therapeutic protein comprised in the nanoparticle.

Abstract: An aerial system, including a processing system, an optical system, an actuation system and a lift mechanism, includes an autonomous photography and/or videography system 70, implemented, at least in part, by the processing system 22, the optical system 26, the actuation system 28 and the lift mechanism 32. The autonomous photograph and/or videography system performs the steps of establishing a desired flight trajectory, detecting a target, controlling the flight of the aerial system as a function of the desired flight trajectory relative to the target using the lift mechanism and controlling the camera to capture pictures and/or video.

Abstract: The present invention provides a multi-connecting rod linkage angle attachment head, including: a casing, a drive mechanism, and a spindle. The drive mechanism includes: a power mechanism, a connecting rod mechanism, and a fixing frame. The fixing frame is fixedly connected to an inner wall of the casing, and the power mechanism is fixedly connected to the fixing frame. The connecting rod mechanism includes: a first connecting rod, a second connecting rod and a third connecting rod. An end of the first connecting rod is rotatably connected to the fixing frame, and is fixedly connected to an output end of the power mechanism. The other end of the first connecting rod is rotatably connected to an end of the third connecting rod via a first pin. The other end of the third connecting rod is rotatably connected to an end of the second connecting rod via a second pin. The other end of the second connecting rod is fixed on a side wall of the spindle.

Abstract: The present invention discloses a multi-degree-of-freedom numerical control turntable including: a B-shaft rotating assembly; a C1-shaft workbench swing assembly; a C2-shaft workbench rotating assembly; and an S-shaft workbench movement assembly. The B-shaft rotating assembly includes a rotating connection land and a B-shaft power control mechanism; the C2-shaft workbench rotating assembly includes a movement base, a workbench and a C2-shaft power control mechanism; the S-shaft workbench movement assembly includes a swing base and an S-shaft power control mechanism; and the C1-shaft workbench swing assembly includes a swing arm and a C1-shaft power control mechanism, with the C1-shaft line intersecting the B-shaft line. The S-shaft power control mechanism can drive the movement base to move along an S-shaft line on the swing base to cause a region to be machined of a workpiece to approach the intersection point of the C1-shaft line and the B-shaft line.

Abstract: Systems, computing platforms, and methods for sampling and analyzing common mode noise on electrocardiogram signals to help to minimize the interference to the electrocardiogram signals are disclosed. Exemplary implementations may: obtain electrocardiogram signals from one or more sensors configured to be attached to a patient and communicatively connected to a patient monitor; receive the electrocardiogram signals from one or more sensors by the patient monitor; display the electrocardiogram signals on one or more displays of the patient monitor; sample and analyze a direct current range and an alternating current spectrum to identify common mode interference levels within the obtained electrocardiogram signals; display the direct current range and the alternating current spectrum via the one or more displays of the patient monitor; and update the display of the direct current range and the alternating current spectrum in real time to identify sources of common mode interference.

Abstract: Nanoparticle are described comprising a tannic acid, a trivalent metal ion, and a pharmaceutical agent comprising a water-soluble biologically active agent, such as a protein, a water-soluble peptide, small molecule or a combination thereof and methods of making and using the nanoparticles. Some nanoparticles of the present invention include 30-60% (w/w) of a tannic acid, 0.1-20% (w/w) of a trivalent metal ion, and 1-50% (w/w) of a pharmaceutical agent.

Abstract: System and method for controlling an aerial system, without physical interaction with a separate remote device, based on sensed user expressions. User expressions may include thought, voice, facial expressions, and/gestures. User expressions may be sensed by sensors associated with the aerial device or a remote device.

Abstract: An aerial system, including a processing system, an optical system, an actuation system and a lift mechanism, includes an autonomous photography and/or videography system 70, implemented, at least in part, by the processing system 22, the optical system 26, the actuation system 28 and the lift mechanism 32. The autonomous photograph and/or videography system performs the steps of establishing a desired flight trajectory, detecting a target, controlling the flight of the aerial system as a function of the desired flight trajectory relative to the target using the lift mechanism and controlling the camera to capture pictures and/or video.

Abstract: A power distribution box assembly can include a power distribution box housing, a fuse block, and a plurality of eyelet terminals. The fuse block can include a stamped busbar assembly, a plurality of studs, and a housing. The stamped busbar assembly can include a main power supply portion, a plurality of fuse elements, and a plurality of terminal connecting portions coupled to the plurality of fuse elements. Each of the plurality of terminal connecting portions can: (i) extend from its respective fuse element in a terminal direction that is orthogonal to both directions that the main power supply portion and the fuse elements extend.