Patents by Inventor Long Liu

Long Liu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250253261
    Abstract: An electronic package and a manufacturing method thereof are provided, in which the electronic package includes: a first circuit module including a dielectric material, a first circuit layer, a second circuit layer, a third circuit layer and a fourth circuit layer; a first electronic element embedded in the first circuit module and electrically connected to the fourth circuit layer; a second circuit module electrically connected to the first circuit layer; and a second electronic element located between the first circuit layer and the second circuit module. Accordingly, the overall thickness of the electronic package can be greatly reduced to save space; the heat dissipation effect of the electronic elements can also be improved to extend their service life; and the manufacturing process can also be effectively simplified to improve yield and production rate and reduce manufacturing costs.
    Type: Application
    Filed: January 17, 2025
    Publication date: August 7, 2025
    Inventors: Yin-Ju CHEN, Jiun-Hua CHIUE, Min-Yao CHEN, De-Long LIU, Andrew C. CHANG, Chung-Hsien YANG, Zhen-Hu CHANG
  • Patent number: 12365926
    Abstract: The invention provides a Saccharomyces cerevisiae strain for producing a human milk lipid substitute. By integrating a heterologous lysophosphatidic acid acyltransferase into Saccharomyces cerevisiae and knocking out its own natural lysophosphatidic acid acyltransferase, the content of palmitic acid (C16:0) at Sn-2 position of triacylglycerol produced by Saccharomyces cerevisiae is increased, to synthesize a human milk lipid substitute. On this basis, a metabolic pathway related gene is knocked out, to further increase the content of human milk lipid substitute in the product. In the present invention, a human milk lipid substitute is de novo synthesized by Saccharomyces cerevisiae for the first time, in which the total fatty acid is 15% or more, and the relative content of C16:0 at Sn-2 position reaches about 60%.
    Type: Grant
    Filed: November 1, 2023
    Date of Patent: July 22, 2025
    Assignees: JIANGNAN UNIVERSITY, INNER MONGOLIA MENGNIU DAIRY (GROUP) COMPANY LIMITED
    Inventors: Long Liu, Jian Chen, Xueqin Lv, Wenyang Wu, Guocheng Du, Jianghua Li, Guolin Zhou, Yanfeng Liu, Chenyang Zhang
  • Publication number: 20250215193
    Abstract: The present disclosure relates to the technical field of organic polymer compounds, in particular to chromatography media for removal of polyphenol substances and a preparation method thereof. A method for preparing chromatography media for the removal of polyphenol substances includes: obtaining an aqueous phase by mixing a water-soluble inorganic salt, a dispersing agent and water; obtaining an oil phase by mixing N-vinyl pyrrolidone, a first crosslinking agent, a second crosslinking agent, a third crosslinking agent, an initiator and a pore-forming agent; and preparing the chromatography media for the removal of the polyphenol substances by adding the oil phase into the aqueous phase for suspension polymerization. The chromatography media of the present disclosure has an effective binding ability for the polyphenol substances in fermented beverages, and an adsorption rate of the polyphenol substances is in a range from 40% to 46%.
    Type: Application
    Filed: December 4, 2024
    Publication date: July 3, 2025
    Applicant: SUNRESIN NEW MATERIALS CO. LTD.
    Inventors: Chenhui LI, Yanjun LI, Long LIU, Kai WANG, Mingxi WANG
  • Publication number: 20250204264
    Abstract: The present disclosure provides a skyrmion transistor and a method of controlling a skyrmion transistor. The transistor includes: a ferromagnetic nanotube; a writing magnetic tunnel junction and a reading magnetic tunnel junction surrounding both ends of the ferromagnetic nanotube respectively; and a ferroelectric ring surrounding an outer side of the ferromagnetic nanotube and located between the writing magnetic tunnel junction and the reading magnetic tunnel junction, where the ferromagnetic nanotube and the ferroelectric ring form a ferromagnetic/ferroelectric heterojunction.
    Type: Application
    Filed: April 20, 2022
    Publication date: June 19, 2025
    Inventors: Guozhong XING, Hao ZHANG, Xuefeng ZHAO, Long LIU, Di WANG, Huai LIN, Ziwei WANG
  • Publication number: 20250188134
    Abstract: The present invention relates to the technical field of protein biological functions, in particular to a polypeptide, a fusion type multimeric protein and use thereof, the polypeptide is selected from: (1), a polypeptide having a substitution mutation in at least one position selected from the group consisting of positions 16, 25, 29, 49 and 58, as compared with a natural C structural domain of a protein A as shown in SEQ ID NO.
    Type: Application
    Filed: December 21, 2022
    Publication date: June 12, 2025
    Inventors: Yanjun LI, Gang LI, Tongnian GU, Jiantao ZHANG, Long LIU, Xiaoju LEI, Qiong LIU
  • Publication number: 20250146393
    Abstract: A method for implementing enhanced oil recovery includes receiving a model of a subterranean volume of at least a portion of an oilfield and measurements collected for the subterranean volume, determining a model confidence index based at least in part on the model and the measurements, selecting one or more physical parameters for candidate pilot tests based at least in part on the model, the measurements, and the model confidence index, designing pilot tests for the individual candidate pilot tests based at least in part on one or more pilot test objectives, the model, and the model confidence index, selecting one or more pilot tests from among the designed pilot tests, and generating a pilot test implementation plan for the selected one or more pilot tests.
    Type: Application
    Filed: August 18, 2022
    Publication date: May 8, 2025
    Inventors: Omer Gurpinar, Jaime Eduardo Moreno Ortiz, Yun Long Liu
  • Patent number: 12293781
    Abstract: The three-state spintronic device includes: a bottom electrode, a magnetic tunnel junction and a top electrode from bottom to top. The magnetic tunnel junction includes: a spin-orbit coupling layer, a ferromagnetic free layer, a barrier tunneling layer, a ferromagnetic reference layer, three local magnetic domain wall pinning centers and domain wall nucleation centers. An antisymmetric exchange interaction is modulated, and the magnetic domain wall pinning centers are embedded in an interface between a heavy metal and the ferromagnetic free layer. The magnetic domain wall nucleation centers are at two ends of the ferromagnetic free layer. A current pulse flows through the spin-orbit coupling layer to generate a spin current and the spin current is injected into the ferromagnetic free layer. Under a control of all-electrical controlled, an effective field of a spin-orbit torque drives domain wall to move and displace.
    Type: Grant
    Filed: January 21, 2021
    Date of Patent: May 6, 2025
    Assignee: INSTITUTE OF MICROELECTRONICS, CHINESE ACADEMY OF SCIENCES
    Inventors: Huai Lin, Guozhong Xing, Zuheng Wu, Long Liu, Di Wang, Cheng Lu, Peiwen Zhang, Changqing Xie, Ling Li, Ming Liu
  • Publication number: 20250131157
    Abstract: A method for creating an artificial intelligence (AI) model is applied to an intelligence processing unit (IPU). The IPU includes a computing circuit and a memory. The AI model includes a plurality of operators. The computing circuit generates an intermediate tensor in the process of executing each operator. The method includes the following steps: (A) dividing the operators according to a batch threshold, life cycles of the intermediate tensors, sizes of the intermediate tensors, and a capacity of the memory; (B) calculating a bandwidth requirement of the IPU for an external memory when executing the AI model; and (C) storing a relationship between the batch threshold and the bandwidth requirement. The AI model performs an operation of the same operator on N batches of input data substantially at the same time, and N is a positive integer.
    Type: Application
    Filed: August 29, 2024
    Publication date: April 24, 2025
    Inventor: Xiao Long Liu
  • Patent number: 12275763
    Abstract: The present invention discloses a RamA transcription factor mutant for promoting the production of N-acetylglucosamine and use thereof. The mutant is obtained by mutating lysine at position 90 to asparagine and serine at position 92 to lysine in a parent having an amino acid sequence as shown in SEQ ID NO: 2. The present invention provides a genetically engineered strain that overexpresses the RamA transcription factor mutant and increases the production of N-acetylglucosamine. By overexpressing the transcription factor RamA that is involved in the regulation of carbon metabolism, the extracellular accumulation of N-acetylglucosamine is increased, with a maximum concentration reaching 31.5 g/L, which lays a foundation for further metabolic engineering of Corynebacterium glutamicum to produce glucosamine. The method for constructing recombinant Corynebacterium glutamicum of the invention is simple, and convenient in use, and thus has good application prospects.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: April 15, 2025
    Assignees: JIANGNAN UNIVERSITY, SHANDONG RUNDE BIOTECHNOLOGY CO., LTD.
    Inventors: Long Liu, Jian Chen, Xueqin Lv, Jianxing Lu, Changfeng Liu, Guocheng Du, Jianghua Li, Chen Deng, Jiangong Lu
  • Publication number: 20250060140
    Abstract: An ice making method for a refrigerator and a refrigerator. The ice making method for a refrigerator comprises: enabling the temperature in an ice making compartment to be higher than or equal to a first preset value; filling an ice making container in the ice making compartment with water; providing cold energy to the ice making compartment according to a first refrigeration capacity, enabling the temperature in the ice making compartment to sequentially drop to reach multiple first preset temperatures, and when the temperature in the ice making compartment drops to reach each first preset temperature, maintaining the temperature in the ice making compartment at the first preset temperature for a corresponding first preset duration, among two adjacent first preset temperatures, the first preset duration corresponding to the lower first preset temperature being shorter than the first preset duration corresponding to the higher first preset temperature.
    Type: Application
    Filed: April 28, 2022
    Publication date: February 20, 2025
    Inventors: Long LIU, Ming WANG, Bintang ZHAO
  • Patent number: 12221640
    Abstract: The present invention provides a method for promoting N-acetylglucosamine synthesis by using the GlcN6P responsive element. In the present invention, Bacillus subtilis BSGNY-Pveg-glmS-P43-GNA1 is used as a starting strain, in which a CRISPRi system regulated by GlcN6P responsive element is integrated into the genome to dynamically weaken the N-acetylglucosamine synthesis competitive pathway; a GlcN6P responsive promoter is used to regulate the expression of GNA1 on the plasmid to dynamically regulate the N-acetylglucosamine synthesis pathway; and the key gene alsSD involved in the acetoin synthesis pathway is knocked out. During fed-batch fermentation with this strain in a 15 L fermenter, the production of N-acetylglucosamine reaches 131.6 g/L and no by-product acetoin is accumulated, which lays a foundation for the production of GlcNAc by industrial fermentation.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: February 11, 2025
    Assignee: JIANGNAN UNIVERSITY
    Inventors: Long Liu, Jian Chen, Guocheng Du, Yaokang Wu, Taichi Chen, Jianghua Li
  • Patent number: 12209549
    Abstract: Disclosed is a combustion system design method based on a target heat release rate, which belongs to the technical field of diesel engine combustion chamber design. The method includes: obtaining an ideal heat release rate based on Sabathe-Miller cycle; simulating the ideal heat release rate based on a double-Wiebe function and obtaining the target heat release rate; constructing a mapping relation among the heat release rate, piston geometric parameters and fuel injection parameters, which includes target start of combustion being an function of fuel injection timing and ignition delay, premixed combustion parameters being functions of throat radius, injection pressure and nozzle diameter, and diffusion combustion being a function of piston pit depth; solving target piston geometric parameters and target fuel injection parameters based on the mapping relation; and then designing a combustion system.
    Type: Grant
    Filed: December 21, 2022
    Date of Patent: January 28, 2025
    Assignee: Harbin Engineering University
    Inventors: Long Liu, Yan Peng, Changfu Han, Haicheng Qi, Li Huang, Wenzheng Zhang
  • Patent number: 12160529
    Abstract: A reconfigurable PUF device based on fully electric field-controlled domain wall motion includes a voltage control layer, upper electrodes, a lower electrode, antiferromagnetic pinning layers, and a magnetic tunnel junction (MTJ). The MTJ includes, from bottom to top, a ferromagnetic reference layer, a potential barrier tunneling layer and a ferromagnetic free layer. In the device, an energy potential well is formed in a middle portion of the ferromagnetic free layer by applying a voltage to the voltage control layer to control magnetic anisotropy, and a current is fed into either of the upper electrodes to drive generation of the magnetic domain walls and pin the magnetic domain walls to the potential well. After the voltage is removed, the potential well is lowered so that the magnetic domain walls are in a metastable state, thereby either a high resistance state or a low resistance state is randomly obtained.
    Type: Grant
    Filed: December 5, 2022
    Date of Patent: December 3, 2024
    Assignee: INSTITUTE OF MICROELECTRONICS OF THE CHINESE ACADEMY OF SCIENCES
    Inventors: Guozhong Xing, Huai Lin, Di Wang, Long Liu, Kaiping Zhang, Guanya Wang, Yan Wang, Xiaoxin Xu, Ming Liu
  • Patent number: 12154609
    Abstract: A magnetoresistive memory cell includes a first magnetic tunnel junction, a second magnetic tunnel junction and a metal layer. The first magnetic tunnel junction and the second magnetic tunnel junction each are disposed on the metal layer; the metal layer is configured to pass write current, a projection line of an easy axis of the first magnetic tunnel junction on a plane where the metal layer is located forms a first angle against a direction of the write current, and a projection line of an easy axis of the second magnetic tunnel junction on the plane where the metal layer is located forms a second angle against a direction opposite to the direction of the write current; the first angle and the second angle are all less than 90°; the first magnetic tunnel junction and the second magnetic tunnel junction are configured to pass read current.
    Type: Grant
    Filed: August 23, 2022
    Date of Patent: November 26, 2024
    Assignee: INSTITUTE OF MICROELECTRONICS OF THE CHINESE ACADEMY OF SCIENCES
    Inventors: Guozhong Xing, Long Liu, Di Wang, Huai Lin, Ming Liu
  • Publication number: 20240374882
    Abstract: A device and methods for producing microneedles includes a microneedle female mold, a vacuum chamber, a filling mechanism and an evacuation mechanism. The vacuum chamber includes a feeding cavity, a filling cavity and a discharging cavity, which are independent of one another. The feeding cavity receives the microneedle female mold therein in non-negative pressure state, and the evacuation mechanism evacuates the feeding cavity that has received the microneedle female mold therein. The filling cavity receives, in negative pressure state, the microneedle female mold transported from the feeding cavity in negative pressure state. The discharging cavity receives, in negative pressure state, the microneedle female mold transported from the filling cavity in negative pressure state and to undergo vacuum destruction after the microneedle female mold is received therein. The device and methods more efficiently produces microneedles in large batches and ensuring formation quality of the produced microneedles.
    Type: Application
    Filed: July 30, 2021
    Publication date: November 14, 2024
    Inventors: Binwen CHEN, Ping YAN, Yuan HUANG, Long LIU, Qiuyu QU
  • Publication number: 20240361102
    Abstract: A front infrared thermal imager includes a user operation module and a front infrared module, where the front infrared module is configured to be arranged at a front end of a daylight scope; and the user operation module is detachably mounted on the front infrared module. In both cases that the user operation module is mounted on and detached from the front infrared module, the user operation module is communicatively connected with the front infrared module, to enable the user operation module to transmit a received user operation instruction to the front infrared module. A detachable remote control module, a front infrared thermal imager and a dual optical scope are further provided.
    Type: Application
    Filed: July 10, 2024
    Publication date: October 31, 2024
    Inventors: Long LIU, Xiaoyu LIU, Youliang ZHAO, Rui GONG
  • Publication number: 20240352972
    Abstract: A method for fabricating the three-dimensional comb-tooth-shaped groove array surface, the surface of the bearing is first etched with grooves having a certain depth by means of femtosecond lase, then a PTFE film is impressed and attached to the surface of the inner ring of the bearing, the position of a laser focus is adjusted to focus on the lower surface of the PTFE film, the same pit is scanned repeatedly, ripple characteristic stripes occur on the surface of the inner ring of the bearing while the film gasifies instantly under the action of laser ablation heating, a part of polymer material in the gasified part is adsorbed to a mechanical surface in each pit under the action of mechanical interlocking, and a super-oleophobic PTFE surface is obtained in each groove.
    Type: Application
    Filed: May 18, 2022
    Publication date: October 24, 2024
    Inventors: Cheng Long LIU, Feng GUO, Bin JU, Xin Ming LI, Qing Hua BAI, Shu Yi LI
  • Publication number: 20240332014
    Abstract: Molecular layer deposition (MLD) is used to provide conformal and uniform doping technology for HAR and reentrant structures. MLD is used to deposit a conformal carbon-based film that contains a doping element. Thermal annealing is then used to make the doping element diffuse into the semiconductor material. For HAR structures, a conformal layer is used with low temperature doping, precise control, and the carbon-based film can be easily removed during doping or after doping. The amount of doping can be controlled by changing the thickness of MLD carbon-based film.
    Type: Application
    Filed: March 22, 2024
    Publication date: October 3, 2024
    Applicants: Applied Materials, Inc., National University of Singapore
    Inventors: Xinke Wang, Long Liu, Mark Saly, Bhaskar Jyoti Bhuyan, Jiecong Tang, John Sudijono
  • Publication number: 20240334838
    Abstract: The present disclosure provides an SOT-MRAM memory cell, including: a bottom electrode; a magnetic tunnel junction layer located on the bottom electrode; an orbital Hall effect layer located on the magnetic tunnel junction layer; a first transistor, a drain of which is connected to the orbital Hall effect layer; and a second transistor, a drain of which is connected to the bottom electrode. The present disclosure further provides an SOT-MRAM memory, an operation method, and an SOT-MRAM memory array.
    Type: Application
    Filed: March 2, 2022
    Publication date: October 3, 2024
    Inventors: Guozhong Xing, Long Liu, Xuefeng Zhao, Di Wang, Huai Lin, Hao Zhang, Ziwei Wang
  • Publication number: 20240302945
    Abstract: Methods, systems, and techniques are provided for displaying objects in virtual network computing (VNC). For example, a VNC connection may be established between a first device and a second device, where the VNC connection enables a synchronization of an interactive display layout from the first device to the second device. Subsequently, after the VNC connection is established, a page structure of the first device may be retrieved based on an application programming interface (API) on the second device. In some embodiments, based on the retrieved page structure, one or more non-interactive objects on the second device may be displayed, where the one or more non-interactive objects are displayed on top of at least a portion of the interactive display layout at the second device.
    Type: Application
    Filed: March 7, 2023
    Publication date: September 12, 2024
    Applicant: MICRO FOCUS LLC
    Inventors: Mingxiang Zhao, Xiao Long Liu, YangHua Hu, Songpei Jin