Abstract: Compounds obtained from the associative synthesis of sulfur-containing or sulfur-free amino acids with derivatives of .DELTA.-4-pregnene-3,20-dione or with derivatives of .DELTA.-1,4-pregnadiene-3,20-dione of the general formulas (I), (II) and (III), having glucocorticoidal and anti-inflammatory properties have been prepared and tested. Pharmaceutical compositions, medicaments containing them as well as their applications are claimed, particularly in the cutaneous and ophthalmic fields.

Abstract: Levorotatory enantiomers of the derivatives of 5,6,13,13a-tetrahydro-8H-dibenzo-[a,g]-quinolizine of formula III ##STR1## wherein R'.sub.3 is hydrogen, an aryl or alkyl group or a --OR or --SR moiety wherein R is hydrogen, an aryl or alkyl group or a group of formula: ##STR2## wherein R" is an aryl or alkyl group, R'.sub.10 and R'.sub.11 which are identical or different, represent hydrogen, an aryloxy, alkoxy or hydroxy group or R'.sub.10 and R'.sub.11 taken together form a --O--(CH.sub.2).sub.n --O-- group in which n is 1 to 3.Application to treatment of cardiovascular disorders.