Abstract: Devices, systems, and methods for treating defects in anatomical structures are disclosed. A device may include a stent having a tubular member with a first end, a second end, and a lumen between the first end and the second end. A wire having a first end and a second end may form a plurality of annular rows between the first end and the second end, where the rows may define the lumen. The wire of the stent may define a plurality of turns in each row of the plurality of annular rows and may have no overlapping portions along the rows. A gap may extend between consecutive rows of the plurality of rows and a connecting segment may span across the gap to interconnect two rows of the plurality of rows. The connecting segment may be the only portion of the wire that spans across the gap.

Abstract: A device for occluding flow of materials is formed as a simple structure permitting a compact delivery configuration which may shift to an expanded deployment configuration. The device has at least one expandable portion formed of a plurality of elongated longitudinally extending frame elements. The frame elements may be spaced apart to define spaces therebetween, and a flexible occlusive material may be provided to block flow of material through such spaces. A flexible occlusive material may form one of two expandable portions of the device without the need for frame elements.

Abstract: Devices, systems, and methods for treating wounds in endoluminal spaces of a patient are disclosed. A device may include an elongate tube defining a proximal end, a distal end, and a lumen, an expandable component adjustably positioned at the distal end of the elongate tube, and a tether coupled to the expandable component and extending proximal from the expandable component through the lumen to a location exterior of the elongate tube. The expandable component may be adjustable between a delivery position within the elongate tube and a fully deployed position at least partially exterior of the elongate tube. The expandable member may be absorbent. A proximal end of the elongate tube may couple to a vacuum source to apply a negative pressure at or proximate the expandable component. An inner member may extend through the elongate tube and be configured to adjustably engage the expandable component.

Abstract: An illustrative stent includes an elongated tubular member comprising at least one strut forming a tubular wall having a plurality of cells extending through a thickness of the tubular wall. The elongated tubular member may be configured to move between a radially collapsed configuration and a radially expanded configuration. A coating may be disposed on the elongated tubular member and spanning at least some of the plurality of cells. One or more magnetic components may be disposed on or within the coating.

Abstract: A medical system includes a porous body positioned at a target site within a subject, a tube including a wall defining a tube lumen, where the tube is connected to the porous body at a first end of the tube, and a sealing device to seal the target site from a body lumen. When the sealing device seals the target site from the body lumen, the tube extends from the target site into the body lumen.

Abstract: A medical device includes a wire or tube, and a porous body coupled a distal portion of the wire or tube. The wire or tube is configured to be transitioned from a first configuration to a second configuration. In the first configuration, the wire or tube is in a flat or straight configuration. In the second configuration, the wire or tube is expanded to a curved or helical shape.

Abstract: A medical system includes a porous body positioned at a target site within a subject, a tube including a wall defining a tube lumen, where the tube is connected to the porous body at a first end of the tube, and a sealing device to seal the target site from a body lumen. When the sealing device seals the target site from the body lumen, the tube extends from the target site into the body lumen.

Abstract: The present disclosure relates to the field of medical devices. Specifically, the present disclosure relates to devices, systems and methods for extending a working channel of an endoscope, such as for delivery of a stent.

Abstract: The present disclosure relates generally to the field of medical devices for accessing body lumens. In particular, the present disclosure relates to medical devices, systems and methods for enlarging an opening of a body lumen. In an embodiment, a device may include a flexible elongate tube. A distal end of the tube may be configured to access an opening of a body lumen. A plurality of wire lumens may extend from the distal end of the tube toward a proximal end of the tube that are radially offset from and substantially parallel with a longitudinal axis. At least a portion of the plurality of wire lumens may be exposed to an outer surface of the tube along a distal portion. A plurality of wires may each extend along a respective wire lumen. A portion of each wire may extend externally to the wire lumens exposed to the outer surface.

Abstract: A system for maintaining patency of a body lumen may include a first endoprosthesis configured to shift from a straightened configuration to a helical configuration defining a plurality of loops, and a second endoprosthesis configured to shift from a radially collapsed configuration toward a radially expanded configuration. The plurality of loops defines a passage having an inner diameter. At least a portion of the second endoprosthesis is disposed within the passage in the radially expanded configuration. A method of maintaining patency of a body lumen may include advancing a first endoprosthesis into a first body lumen in a straightened configuration, deploying the first endoprosthesis within the first body lumen in a helical configuration defining a plurality of loops, advancing a second endoprosthesis into the first body lumen in a radially collapsed configuration, and shifting the second endoprosthesis to a radially expanded configuration within the plurality of loops.

Abstract: An endoprosthesis includes an elongated tubular member including a filament forming circumferential rows having a plurality of knitted loops and intermediate rungs extending between adjacent knitted loops. The tubular member includes at least one window and may include a plurality of anti-migration loops adjacent the at least one window and configured to shift between first and second positions when unconstrained. Making the endoprosthesis includes forming the plurality of knitted loops and intermediate rungs in a first row of loops and rungs, extending the filament to form a second row of loops and rungs interwoven with the first row, and forming the at least one window without cutting the filament. Placing the endoprosthesis includes positioning the endoprosthesis within a body lumen adjacent a branch lumen, expanding the tubular member to span the branch lumen, and shifting at least some anti-migration loops toward the second position and into the branch lumen.

Abstract: An esophageal atresia bridge device including a proximal anchor, a distal anchor, and a brace extending between the proximal anchor and the distal anchor. The brace permits the proximal anchor to move toward the distal anchor to apply a controlled tension that pulls the esophagus together and stretches the esophagus over time. A method of treating esophageal atresia may include inserting an elongate member of an esophageal atresia device into a mouth of a patient, the esophageal atresia device including a rotatable member including a threaded region, and rotating the rotatable member relative to the elongate member to longitudinally move the distal end of the elongate member relative to the rotatable member in order to apply a force to a proximal pouch of the patient's esophagus.

Abstract: A stent may include a radially expandable tubular framework includes a first end region, a second end region, a medial region positioned between the first end region and the second end region, and a lumen extending therethrough. The radially expandable tubular framework is configured to expand from a radially collapsed configuration to a radially expanded configuration. A plurality of covering strips are positioned along at least one of the first end region, the medial region, and the second end region. The plurality of covering strips fully covering the radially expandable tubular framework in the radially collapsed configuration, and the plurality of covering strips are configured to separate from one another in the radially expanded configuration to expose portions of the radially expandable tubular framework therebetween.

Abstract: The present disclosure relates to the field of medical devices. Specifically, the present disclosure relates to devices, systems and methods for extending a working channel of an endoscope, such as for delivery of a stent.

Abstract: A system for maintaining patency of a body lumen may include a first endoprosthesis configured to shift from a straightened configuration to a helical configuration defining a plurality of loops, and a second endoprosthesis configured to shift from a radially collapsed configuration toward a radially expanded configuration. The plurality of loops defines a passage having an inner diameter. At least a portion of the second endoprosthesis is disposed within the passage in the radially expanded configuration. A method of maintaining patency of a body lumen may include advancing a first endoprosthesis into a first body lumen in a straightened configuration, deploying the first endoprosthesis within the first body lumen in a helical configuration defining a plurality of loops, advancing a second endoprosthesis into the first body lumen in a radially collapsed configuration, and shifting the second endoprosthesis to a radially expanded configuration within the plurality of loops.

Abstract: The present disclosure relates generally to the field of medical devices for accessing body lumens. In particular, the present disclosure relates to medical devices, systems and methods for enlarging an opening of a body lumen. In an embodiment, a device may include a flexible elongate tube. A distal end of the tube may be configured to access an opening of a body lumen. A plurality of wire lumens may extend from the distal end of the tube toward a proximal end of the tube that are radially offset from and substantially parallel with a longitudinal axis. At least a portion of the plurality of wire lumens may be exposed to an outer surface of the tube along a distal portion. A plurality of wires may each extend along a respective wire lumen. A portion of each wire may extend externally to the wire lumens exposed to the outer surface.

Abstract: A lumen-apposing access system may include a catheter and a cauterization tip. The cauterization tip may include a biasing member and a cautery element. The cauterization tip may move relative to the catheter between a first position in which the cautery element is electrically inactive, and a second position in which the cautery element is electrically active. The biasing member biases the cautery element in the first position.

Abstract: An esophageal stent may include an expandable framework having a first end, a second end, and a central longitudinal axis extending from the first end to the second end, the expandable framework being configured to expand from a radially collapsed configuration to a radially expanded configuration, and a polymeric outer sleeve disposed radially outward of and spaced apart from a body region of the expandable framework. The expandable framework may include a plurality of anti-migration supports extending radially outward from the body region of the expandable framework toward the polymeric outer sleeve.

Abstract: An illustrative stent includes an elongated tubular member comprising at least one strut or filament forming a tubular wall having a plurality of cells extending through a thickness of the tubular wall. The elongated tubular member may be configured to move between a radially collapsed configuration and a radially expanded configuration. A coating is disposed on the elongated tubular member and spanning the plurality of cells. The coating forms a pocket within at least some of the cells of the plurality of cells and extends radially inward of the tubular wall to define a void. In some instances, a partition or wall is positioned within at least some of the pockets and transects the void.

Abstract: A lumen-apposing access system may include a catheter and a cauterization tip. The cauterization tip may include a biasing member and a cautery element. The cauterization tip may move relative to the catheter between a first position in which the cautery element is electrically inactive, and a second position in which the cautery element is electrically active. The biasing member biases the cautery element in the first position.