Abstract: Methods and systems for key generation and device management are disclosed. A root key can be stored on a component which can be integrated with a device, and the component can store a product class identifier. The product class identifier can define a class of products, devices, features, hardware components, or other entities. One or more keys can be generated and stored on the devices based on the product class identifier and the root key. A network operator or service provider can then provide services to a class of devices that includes the device, or perform and manage other functions. The services can be authorized or otherwise implemented based on the one or more new keys stored at the devices within the class of devices.

Abstract: The present invention provides a compound of formula (1) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: A thermoformable biaxially oriented coextruded polyester film comprising a copolyester base layer B, a first polyester outer layer A1 and a second polyester outer layer A2, wherein said outer layers are disposed on opposite surfaces of said base layer, and wherein: (i) said base layer B comprises a copolyester derived from terephthalic acid (TA) and a second aromatic dicarboxylic acid and one or more diol(s), wherein said second aromatic dicarboxylic acid is present in the copolyester in an amount of from about 5 to about 20 mol % of the acid fraction of the copolyester; (ii) the polyester of each of said outer layers A1 and A2 is selected from polyethylene terephthalate (PET); and (iii) the thickness of the base layer constitutes at least 90% of the total thickness of the coextruded multi-layer polyester film.

Abstract: A thermoformable biaxially oriented coextruded polyester film comprising a copolyester base layer B, a first polyester outer layer A1 and a second polyester outer layer A2, wherein said outer layers are disposed on opposite surfaces of said base layer, and wherein: (i) said base layer B comprises a copolyester derived from terephthalic acid (TA) and a second aromatic dicarboxylic acid and one or more diol(s), wherein said second aromatic dicarboxylic acid is present in the copolyester in an amount of from about to 5 about 20 mol % of the acid fraction of the copolyester; (ii) the polyester of each of said outer layers A1 and A2 is selected from polyethylene terephthalate (PET); and (iii) the thickness of the base layer constitutes at least 90% of the total thickness of the coextruded multi-layer polyester film.

Abstract: The present invention relates to urinary catheters, in particular indwelling urinary catheters, with self-sterilising capabilities. There is disclosed a catheter for insertion into the bladder of a patient, the catheter comprising an elongate body having a distal portion configured to reside in the patient's body, and a proximal portion configured to be left outside of the body of the patient. The catheter may further comprise at least one light generator provided within the distal portion of the elongate body so as to emit light, wherein said light comprises sterilising light.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: A thermoformable biaxially oriented coextruded polyester film comprising a copolyester base layer B, a first polyester outer layer A1 and a second polyester outer layer A2, wherein said outer layers are disposed on opposite surfaces of said base layer, and wherein: (i) said base layer B comprises a copolyester derived from terephthalic acid (TA) and a second aromatic dicarboxylic acid and one or more diol(s), wherein said second aromatic dicarboxylic acid is present in the copolyester in an amount of from about to 5 about 20 mol % of the acid fraction of the copolyester; (ii) the polyester of each of said outer layers A1 and A2 is selected from polyethylene terephthalate (PET); and (iii) the thickness of the base layer constitutes at least 90% of the total thickness of the coextruded multi-layer polyester film.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: A container includes a movable cover for an opening of the container. The cover can be attached to the container to rotate from a first position to a second position to be disposed over the opening in the container. When the cover is in the first position, the opening is at least substantially uncovered, and when the cover is in the second position, the opening is at least substantially covered.

Abstract: The present invention provides a compound of formula I The compounds of formula I demonstrate properties as Smurf-1 inhibitors and are thus useful in the treatment of a range of disorders, particularly pulmonary arterial hypertension.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

Abstract: A container includes a movable cover for an opening of the container. The cover can be attached to the container to rotate from a first position to a second position to be disposed over the opening in the container. When the cover is in the first position, the opening is at least substantially uncovered, and when the cover is in the second position, the opening is at least substantially covered.