Abstract: The present invention provides methods of treating gastrointestinal disorders with modulators of the WNT signaling pathway. Also provided are methods of dosing and pharmaceutical compositions.

Abstract: Embodiments of the disclosure provide an optical sensing system, an integrated transmitter module for the optical sensing system, and an optical sensing method performed using the optical sensing system. The exemplary optical sensing system includes an integrated transmitter module configured to emit an optical signal into an environment surrounding the optical sensing system. The integrated transmitter module includes a laser emitter, one or more driving integrated circuits, and one or more optics integrated into a chamber that is hermetically sealed. The optical sensing system further includes a photodetector configured to receive the optical signal reflected from the environment and convert the received optical signal to an electrical signal. The optical sensing system additionally includes a readout circuit configured to convert the electrical signal to a digital signal. The photodetector and the readout circuit are located outside the chamber enclosing the integrated transmitter module.

Abstract: An optical element drive mechanism is provided. The optical element drive mechanism includes an immovable part, a movable part, a drive assembly, and a strengthening assembly. The movable part is connected to an optical element. The movable part is movable relative to the immovable part. The drive assembly drives the movable part to move relative to the immovable part. The strengthening assembly strengthens the driving force of the drive assembly. The strengthening assembly is close to the drive assembly.

Abstract: The present disclosure provides an unmanned aerial vehicle platform based vision measurement method for a static rigid object. Aiming at the problem of high professionality but poor versatility of existing vision measurement methods, the present disclosure uses a method combining object detection and three-dimensional reconstruction to mark an object to be measured, and uses a three-dimensional point cloud processing method to further mark a size to be measured and calculate its length, which takes full advantage of the convenience of data collection by an unmanned aerial vehicle platform (UAV), and its global navigation satellite system (GNSS), an inertial measurement unit (IMU) and the like to assist measurement. There is no need to use common auxiliary devices such as a light pen and a marker, which can improve the versatility of vision measurement.

Abstract: The present invention relates to a WEE1 inhibitor, and the preparation and use thereof. The WEE1 inhibitor of the present invention is a compound of Formula I or a compound of Formula II, or a pharmaceutically acceptable salt, solvate, polymorph or tautomer thereof. The present invention also provides use of the WEE1 inhibitor in the manufacture of a medicament for the treatment of a disease associated with WEE1 activity. The WEE1 inhibitor provided by the present invention can effectively treat the disease associated with WEE1 activity.

Abstract: Methods and apparatus are provided for unified significance map coding. An apparatus includes a video encoder (400) for encoding transform coefficients for at least a portion of a picture. The transform coefficients are obtained using a plurality of transforms. One or more context sharing maps are generated for the transform coefficients based on a unified rule. The one or more context sharing maps are for providing at least one context that is shared among at least some of the transform coefficients obtained from at least two different ones of the plurality of transforms.

Abstract: A display panel and a display device. The display panel includes a first display area, a second display area and a transition display area between the first display area and the second display area. A light transmittance of the first display area is greater than a light transmittance of the second display area. The display panel includes a plurality of columns of first sub-pixels disposed in the transition display area arranged in a first direction, and each column of sub-pixels includes a plurality of first sub-pixels arranged in a second direction which intersects the first direction. A plurality of first pixel circuits corresponding to at least one column of first sub-pixels are distributed on a same column.

Abstract: A calibration system and related methods for optical phased array chips. The calibration system includes an adjustable mount module, an infrared microscopic observation module, an arrayed driver module, a two-dimensional laser beam scanning module, a photoelectric conversion module and an upper computer, and utilizes computer-vision-enabled positioning and phase error compensation algorithms as software components. Collimated laser is emitted from the target beamforming angle and aimed at the emission aperture of the chip, and is subsequently sampled by the array elements in a reversed injection manner. Based on the reciprocity of light propagation, by maximizing the power reversely output from the bus waveguide of the optical phased array chip, beamforming at the target angle is achieved supported by software implementations of optimization algorithms.

Abstract: Provided are a display substrate, a tiled display panel and a display device, relating to the field of display technology. The display substrate comprises a base substrate, and a plurality of light-emitting units, a protective layer and a connecting wire which are sequentially stacked in a direction away from the base substrate. One end of the connecting wire is connected to the plurality of light-emitting units through a via hole provided in the protective layer, and the other end is used for connecting a drive circuit, that is, the drive circuit can be directly provided at a side of the protective layer away from the base substrate. When a plurality of display substrates are tiled to form a tiled display panel, there is no need to bend a flexible circuit board at sides of each display substrate, and therefore, the gap between every two adjacent display substrates is small, and the display effect is good.

Abstract: A smoking substitute apparatus is disclosed, having: an air inlet; an outlet; and a flow passage formed between the air inlet and the outlet. A vaporization chamber is in communication with the flow passage, the vaporization chamber having an aerosol generator configured to generate an aerosol from an aerosol precursor by heating. The aerosol generator comprises a vaporizer element loaded with aerosol precursor, the vaporizer element being heatable by a heater and presenting a vaporizer element surface to air in the vaporization chamber. The air inlet, flow passage, outlet and the vaporization chamber are configured so that the cooling rate of the vapor is such that the time taken to cool to 50° C. is not less than 16 ms under certain conditions.

Abstract: A laser package is mounted on the printed circuit board. At least one thermal via extends through the printed circuit board, coupled to the laser package. A thermal bridge is coupled to the at least one thermal via on the bottom of the printed circuit board. A thermal paste connects the thermal bridge to a conductive ground plane on the bottom of the printed circuit board, and to a mechanical housing.

Abstract: An electronic device has pixels that form an active area of a display for displaying images for a user. A layer of black ink or other opaque material may be formed on an inner surface of a display cover layer in an inactive area of the display that does not overlap pixels. The housing may have sidewalls such as a rear housing wall that faces away from the display. Ambient light sensor windows may be formed from tapered holes or other holes. The tapered holes may be formed in the opaque material on the display cover layer, may be formed in a rear housing wall or other hosing structure, or may be formed in other portions of the electronic device. Non-tapered holes may also form windows. Tapered holes may have sidewalls with portions that run parallel to their longitudinal axes and portions that are angled relative to their longitudinal axes.

Abstract: The disclosure provides an electronic device and a display method thereof. The electronic device includes a display panel and a light source module. The light source module is disposed at a side of the display panel. The light source module includes a first group of light-emitting units and a second group of light-emitting units that are alternately arranged, wherein the first group of light-emitting units and the second group of light-emitting units emit a light alternately, and each of a plurality of display pixels is adapted to alternately receive the light from the first group of light-emitting units and the second group of light-emitting units.

Abstract: Methods, systems, and computer-readable media for adjustment of display of applications on an endpoint device are presented. A computing device may receive coordinates for an endpoint device. The coordinates may be representative of dimensions of a canvas on which to render an image for display on a screen of the endpoint device. Subsequently, the computing device may provide an image of a remote application to the endpoint device. Then, the computing device may provide information to the endpoint device in response to receipt of input by the endpoint device. The input by the endpoint device may be an input received on the image of the remote application and may be indicative of an editable area of the canvas. The information provided by the computing device may enable adjustment of a size or location of an input area of the canvas.

Abstract: A computerized system for verifiably pairing financial events including a loan with a digital representation and a check cashing transaction with a digital representation comprising: a kiosk and controller in communication with a persistent storage; a sensor assembly in communications with the controller wherein the sensor assembly is adapted for sensing a borrower application as the loan origination location; a set of non-transitory computer readable instructions included in controller adapted for: determining the location of the kiosk, retrieving, from the persistent storage, a loan record representing loan from a lender to a borrower, creating a payment record including payment information captured by the sensor assembly representing a payment according to the loan record from the borrower wherein the payment record includes the date, time, payor, amount, location and any combination, associating the payment record with the loan record and storing the payment record on the persistent storage.

Abstract: A method for detecting groceries in corridor is provided, this method includes: obtaining an image collected from a corridor, performing pedestrian detection and grocery detection on the image collected from the corridor to obtain a pedestrian detection result and a grocery detection result; performing, if there is a pedestrian image in the pedestrian detection result, an image processing on the image collected from the corridor according to the pedestrian image; comparing the image that is collected from the corridor and has been processed with a preset corridor image to obtain an image similarity; generating, if there is a grocery image in the grocery detection result, or if the image similarity is less than or equal to a similarity threshold, a grocery cleaning instruction according to an identifier of corridor in the image collected from the corridor; and sending a grocery cleaning prompt according to the grocery cleaning instruction.

Abstract: This disclosure relates to a signal generating circuit and an audio processing device. The circuit includes a switch module, a voltage producing module, and a signal generating module; the switch module is connected to the voltage producing module, including at least one control switch, and is used for receiving a frequency division signal. Based on the frequency division signal, the at least one control switch is turned on or turned off; the voltage producing module is separately connected to the switch module and the signal generating module and used for producing a first voltage and a second voltage. The at least one control switch controls the first voltage and the second voltage to change. The signal generating module is connected to the voltage producing module and used for generating a carrier signal with the same frequency as the frequency division signal according to the received first and second voltages.

Abstract: An optoelectronic structure includes a substrate, an electronic die and a photonic die. The electronic die is disposed on the substrate and includes a first surface, wherein the first surface is configured to support an optical component. The photonic die is disposed on the first surface of the electronic die and has an active surface toward the first surface of the electronic die and a side surface facing the optical component.

Abstract: The present disclosure provides a method and device in nodes used for wireless communication. A first node receives a first signaling, the first signaling is used to indicate a first symbol set; and then operates a first radio signal in only a first symbol group in the first symbol set. The first signaling is used to indicate scheduling information of the first radio signal; any multicarrier symbol in the first symbol group belongs to the first symbol set, and a number of multicarrier symbol(s) comprised in the first symbol group is not greater than a number of multicarrier symbol(s) comprised in the first symbol set; a target TDD configuration is used to determine a type of each multicarrier symbol in the first symbol set, the target TDD configuration is used to determine the first symbol group out of the first symbol set.

Abstract: A semiconductor device package and a method for manufacturing a semiconductor device package are provided. The semiconductor device package includes a carrier, a sensor module, a connector, and a stress buffer structure. The sensor module is disposed on the carrier. The connector is connected to the carrier. The stress buffer structure connects the connector to the sensor module.