Patents by Inventor Lu Huang-An

Lu Huang-An has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200105020
    Abstract: A method of spectral analyzing with a color camera is provided, and the method includes: calibrating a color camera to obtain a quantum efficiency database of the color camera; shooting a detection area with the color camera, the detection area including at least one object, to obtain the color content data of the at least one object; and comparing the color content data to the quantum efficiency database to analyze the at least one object.
    Type: Application
    Filed: October 1, 2019
    Publication date: April 2, 2020
    Inventors: Chi-Yuan LIN, Cheng-En CHIANG, Hung Chun LO, Chun Pin HSU, Chi Lu HUANG, Chao-Yu HUANG, Cheng-Tao TSAI
  • Patent number: 10525083
    Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD20 or CD22. The invention also relates to chimeric antigen receptor (CAR) specific to CD20 or CD22, vectors encoding the same, and recombinant T or natural killer (NK) cells comprising the CD20 CAR or CD22 CAR. The invention also includes methods of administering a genetically modified T cell or NK cell expressing a CAR that comprises a CD20 or CD22 binding domain.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: January 7, 2020
    Assignees: Novartis AG, The Trustees of the University of Pennsylvania
    Inventors: Barbara Brannetti, Jennifer Brogdon, Boris Engels, Brian Granda, Lu Huang, Ming Lei, Na Li, Jimin Zhang, Carla Guimaraes
  • Publication number: 20190382500
    Abstract: The invention provides compositions and methods for treating diseases associated with expression of BCMA. The invention also relates to chimeric antigen receptor (CAR) specific to BCMA, vectors encoding the same, and recombinant T cells comprising the BCMA CAR. The invention also includes methods of administering a genetically modified T cell expressing a CAR that comprises a BCMA binding domain.
    Type: Application
    Filed: June 12, 2019
    Publication date: December 19, 2019
    Inventors: Aida Abujoub, John Blankenship, Dexiu Bu, Tony Fleming, Brian Holmberg, Connie Hong, Lu Huang, Chonghui Zhang
  • Publication number: 20190375756
    Abstract: Disclosed in the present invention are a salt type and crystal type of 4H-pyrazolo[1, 5-alpha]benzimidazole compound and the preparation method and intermediate thereof.
    Type: Application
    Filed: August 22, 2019
    Publication date: December 12, 2019
    Inventors: Xuehai WANG, Charles Z. DING, Jie SHEN, Shuhui CHEN, Lie LI, Gang LI, Yong XU, Cailin WANG, Ronghua TU, Jimeng WANG, Yang YUE, Biao DENG, Hailiang CHEN, Hui LIU, Wenjie SUN, Cong WANG, Lu HUANG, Zheng WANG, Weidong LI
  • Publication number: 20190367628
    Abstract: The present disclosure provides BCMA binding molecules that specifically bind to human BCMA, conjugates comprising the BCMA binding molecules, and pharmaceutical compositions comprising the BCMA binding molecules and the conjugates. The disclosure further provides methods of using the BCMA binding molecules to treat cancers that express cell surface BCMA. The disclosure yet further provides recombinant host cells engineered to express the BCMA binding molecules and methods of producing the BCMA binding molecules by culturing the host cells under conditions in which the BCMA binding molecules are expressed.
    Type: Application
    Filed: May 30, 2019
    Publication date: December 5, 2019
    Inventors: Aida ABUJOUB, John BLANKENSHIP, Tony FLEMING, Brian HOLMBERG, Connie HONG, Lu HUANG, Haihui LU
  • Patent number: 10428073
    Abstract: Disclosed in the present invention are a salt type and crystal type of 4H-pyrazolo[1,5-alpha]benzimidazole compound and a preparation method and intermediate thereof.
    Type: Grant
    Filed: September 29, 2016
    Date of Patent: October 1, 2019
    Assignees: Hubei Bio-Pharmaceutical Industrial Technological Institute Inc., Humanwell Healthcare (Group) Co., Ltd.
    Inventors: Xuehai Wang, Charles Z. Ding, Jie Shen, Shuhui Chen, Lie Li, Gang Li, Yong Xu, Cailin Wang, Ronghua Tu, Jimeng Wang, Yang Yue, Biao Deng, Hailiang Chen, Hui Liu, Wenjie Sun, Cong Wang, Lu Huang, Zheng Wang, Weidong Li
  • Publication number: 20190292238
    Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD19, e.g., by administering a recombinant T cell comprising the CD19 CAR as described herein, in combination with one or more B-cell inhibitors, e.g., inhibitors of one or more of CD10, CD20, CD22, CD34, CD123, FLT-3, ROR1, CD79b, CD179b, or CD79a. The disclosure additionally features novel antigen binding domains and CAR molecules directed to CD20 and CD22, and uses, e.g., as monotherapies or in combination therapies. The invention also provides kits and compositions described herein.
    Type: Application
    Filed: January 24, 2019
    Publication date: September 26, 2019
    Inventors: Hans Bitter, Jennifer Mary Bordeaux, Barbara Brannetti, Jennifer Brogdon, Naveen Kumar Dakappagari, Saar Gill, Steven Highfill, Lu Huang, Carl H. June, Ju Young Kim, Ming Lei, Na Li, Andreas Loew, Elena Orlando, Marco Ruella, Thai Tran, Jimin Zhang, Li Zhou
  • Publication number: 20190209638
    Abstract: A natural composition that includes C. osmophloeum and C. pinnatifida. The C. osmophloeum is an aqueous extract of Cinnamomum osmophloeum leaves. The Crataegus pinnatifida is an aqueous extract of C. pinnatifida fruit. The weight ratio of the C. osmophloeum to the C. pinnatifida is 1:0.05-2, the preferred ratio is 1:0.5-1.5, and the optimal ratio is 1:0.9-1.1. The pharmaceutical composition has an ?-glucosidase inhibition effect. The natural composition can further inhibit ?-amylase to regulate the absorption of blood glucose and carbohydrate.
    Type: Application
    Filed: January 5, 2018
    Publication date: July 11, 2019
    Inventors: Hsiu-Man Lien, Chia-Chang Chen, Sheau-Jiun Chang, Chao-Lu Huang, Jui-Ting Hsu
  • Patent number: 10344401
    Abstract: A method for manufacturing a nylon 66 hollow fiber includes steps as follows. A plurality of nylon 66 particles are provided. A melting step is provided, wherein the nylon 66 particles are melted so as to form a spun liquid. A fiber spitting step is provided, wherein the spun liquid goes through a hollow spinneret plate so as to form hollow nascent fibers. An evacuating step is provided, wherein the hollow nascent fibers are preliminarily solidified so as to form hollow half-solidified fibers. A cooling step is provided, wherein the hollow half-solidified fibers are cooled and solidified so as to form solidified fibers. A collecting and oiling step is provided. A drawing step is provided. A winding step is provided so as to obtain the nylon 66 hollow fiber.
    Type: Grant
    Filed: January 10, 2016
    Date of Patent: July 9, 2019
    Assignee: CHAIN YARN CO., LTD.
    Inventors: Yen-Hsiao Chen, Chung-Chen Wu, Chi-Lu Huang, Chuan-Shing Lin
  • Publication number: 20190157692
    Abstract: A modular apparatus of fuel cell system includes a start burner, a reformer, an after-burner, and a heat exchanger. The start burner, the reformer, the after-burner, and the heat exchanger are disposed in a chamber. The start burner is surrounded by the reformer, and the after-burner is disposed on the start burner and surrounds the reformer. The heat exchanger surrounds the after-burner and the reformer.
    Type: Application
    Filed: November 20, 2017
    Publication date: May 23, 2019
    Applicant: Industrial Technology Research Institute
    Inventors: Cheng-Hao Yang, Heng-Ju Lin, Fu-Pin Ting, Jar-Lu Huang, Jia-Syun Lyu
  • Publication number: 20190147153
    Abstract: A mechanism is provided for enhancing security access to a data processing system. Responsive to authenticating a first factor of the multi-factor authentication by matching a scanned fingerprint/thumbprint of a user to at least one previously scanned fingerprint/thumbprint in a set of previously scanned fingerprints/thumbprints, a determination is made as to whether a touch pressure level exerted by the user on a touch pressure sensor associated with the data processing system matches at least one previously stored touch pressure level in a set of previously stored touch pressure levels. Responsive to matching the touch pressure level exerted by the user to a previously stored touch pressure level in the set of previously stored touch pressure levels, a second factor of the multi-factor authentication is authenticated. Access is then granted for the user to the data processing system.
    Type: Application
    Filed: November 16, 2017
    Publication date: May 16, 2019
    Inventors: Song Bai, Xiang Cai, Xue Mei Deng, Lu Huang, Yang Liang, Yin Qian
  • Publication number: 20190148746
    Abstract: A hydrogen circulation system for fuel cell includes a hydrogen supply pipeline, a return pipeline, a buffer tank, an ejector, a differential pressure valve, a solenoid valve, and a controller. The return pipeline connects a hydrogen outlet of a fuel cell stack and the hydrogen supply pipeline. The buffer tank is installed at the return pipeline. The ejector is installed at the hydrogen supply pipeline for connecting the buffer tank. The differential pressure valve is between a hydrogen source and the ejector for adjusting a pressure in the hydrogen supply pipeline based on a pressure difference between an anode inlet and a cathode inlet of the fuel cell stack. The solenoid valve is installed at the return pipeline between the buffer tank and the hydrogen outlet. According to an output voltage or a load of the fuel cell stack, a switch of the solenoid valve is controlled by the controller.
    Type: Application
    Filed: December 20, 2017
    Publication date: May 16, 2019
    Applicant: Industrial Technology Research Institute
    Inventors: Chun-han Li, Reiko Ohara, Jar-Lu Huang, Ya-Yi Hsu, Ming-Tao Hu
  • Patent number: 10253086
    Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD19, e.g., by administering a recombinant T cell comprising the CD19 CAR as described herein, in combination with one or more B-cell inhibitors, e.g., inhibitors of one or more of CD10, CD20, CD22, CD34, CD123, FLT-3, ROR1, CD79b, CD179b, or CD79a. The disclosure additionally features novel antigen binding domains and CAR molecules directed to CD20 and CD22, and uses, e.g., as monotherapies or in combination therapies. The invention also provides kits and compositions described herein.
    Type: Grant
    Filed: April 8, 2016
    Date of Patent: April 9, 2019
    Assignees: Novartis AG, The Trustees of the University of Pennsylvania
    Inventors: Hans Bitter, Jennifer Mary Bordeaux, Barbara Brannetti, Jennifer Brogdon, Naveen Kumar Dakappagari, Saar Gill, Steven Highfill, Lu Huang, Carl H. June, Ju Young Kim, Ming Lei, Na Li, Andreas Loew, Elena Orlando, Marco Ruella, Thai Tran, Jimin Zhang, Li Zhou
  • Publication number: 20180338973
    Abstract: The present invention provides a pyrimidine derivative and a use thereof. The pyrimidine derivative is the compound shown in formula I or a pharmaceutically acceptable salt, hydrate, solvate, metabolite or prodrug thereof, wherein, R1, R2, R3, R4 and R5 are, for example, as defined in the specification. The compound can act as an ALK inhibitor, and is for preparing an anti-tumor medicament for suppressing an anaplastic lymphoma kinase.
    Type: Application
    Filed: November 4, 2016
    Publication date: November 29, 2018
    Inventors: Xuehai Wang, Yong Xu, Xijun Sheng, Xiaolin Zhang, Hangui Xia, Zhongwen Yang, Yang Yue, Lu Huang, Qiang Xiao
  • Publication number: 20180258093
    Abstract: Disclosed in the present invention are a salt type and crystal type of 4H-pyrazolo[1, 5-alpha]benzimidazole compound and the preparation method and intermediate thereof.
    Type: Application
    Filed: September 29, 2016
    Publication date: September 13, 2018
    Inventors: Xuehai WANG, Charles Z. DING, Jie SHEN, Shuhui CHEN, Lie LI, Gang LI, Yong XU, Cailin WANG, Ronghua TU, Jimeng WANG, Yang YUE, Biao DENG, Hailiang CHEN, Hui LIU, Wenjie SUN, Cong WANG, Lu HUANG, Zheng WANG, Weidong LI
  • Patent number: 9992104
    Abstract: The present disclosure provides a communication method, a communication system, a resource pool management system, a switch device and a control device in a Software-Defined Network (SDN).
    Type: Grant
    Filed: December 31, 2014
    Date of Patent: June 5, 2018
    Assignee: China Mobile Communications Corporation
    Inventors: Chen Li, Lu Huang, Zhiheng Liu
  • Publication number: 20180125892
    Abstract: The invention provides compositions and methods for treating diseases associated with expression of CD20 or CD22. The invention also relates to chimeric antigen receptor (CAR) specific to CD20 or CD22, vectors encoding the same, and recombinant T or natural killer (NK) cells comprising the CD20 CAR or CD22 CAR. The invention also includes methods of administering a genetically modified T cell or NK cell expressing a CAR that comprises a CD20 or CD22 binding domain.
    Type: Application
    Filed: October 6, 2017
    Publication date: May 10, 2018
    Inventors: Barbara Brannetti, Jennifer Brogdon, Boris Engels, Brian Granda, Lu Huang, Ming Lei, Na Li, Jimin Zhang, Carla Patricia Pinto Guimaraes
  • Patent number: 9856262
    Abstract: Disclosed is a series of analogs of 4H-pyrazolo[1,5-?]benzimidazole compound as PARP inhibitors. In particular, disclosed in the invention is a compound as shown by formula (I) or a pharmaceutically acceptable salt thereof as a PARP inhibitor.
    Type: Grant
    Filed: March 30, 2015
    Date of Patent: January 2, 2018
    Assignees: Hubei Bio-Pharmaceutical Industrial Technological Institute Inc., Humanwell Healthcare (Group) Co., Ltd., Medshine Discovery Inc.
    Inventors: Xuehai Wang, Zhaozhong Ding, Yong Xu, Shuhui Chen, Lie Li, Gang Li, Ronghua Tu, Cailin Wang, Yang Yue, Zhibo Zhang, Hailiang Chen, Wenjie Sun, Lu Huang
  • Patent number: D853980
    Type: Grant
    Filed: February 3, 2017
    Date of Patent: July 16, 2019
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Joon Suh Kim, Ting Xu, Zhenqi Tang, Lu Huang
  • Patent number: D864141
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: October 22, 2019
    Assignee: HUAWEI TECHNOLOGIES CO., LTD.
    Inventors: Joon Suh Kim, Ting Xu, Lu Huang, Jiaxi Wang, Qingmeng Li