Abstract: Provided are an antibody and an antigen-binding fragment that specifically bind to Nectin-4, and a test kit containing the antibody or the antigen-binding fragment. Also provided are a nucleic acid encoding the antibody, a host cell containing the nucleic acid, and a method for preparing the antibody. Also provided are uses of the antibody specifically binding to Nectin-4 in diagnosis and prognosis.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for generating images. For example, the system can perform low-latency on-device image generation using a generator neural network.

Abstract: An injectable formulation, comprising: poly(lactic-co-glycolic (PLGA) microsphere encapsulating siltuximab, wherein microspheres are sized to release siltuximab over a period of hours, days and weeks, where the biocompatible polymer releases antibody at an absorption rate which is characterized by an absorption rate constant (Ka (h?1) in the range of (0.001 to 2.048)+/?20%, or +/?10%, or +/?5% . . . for use and treating human patients with infections. The invention includes treating patients with viral infections of SARS-Cov-2 using siltuximab.

Abstract: A light-adjusting structure includes a first base layer and a second base layer, a first conductive layer and a second conductive layer sandwiched between the first base layer and the second base layer, the first conductive layer being attached to the first base layer and the second conductive layer being attached to the second base layer; and a light-adjusting layer sandwiched between the first conductive layer and the second conductive layer; wherein the light-adjusting structure is provided with an edge-sealing area which penetrates through at least a part of the first base layer, the first conductive layer, the light-adjusting layer and/or at least a part of the second base layer, the second conductive layer and the light-adjusting layer, and the edge-sealing area is configured to be matched with a first edge-sealing material or provided with the first edge-sealing material.

Abstract: A multi-level conversion circuit and a cycle-by-cycle protection method therefor are provided. The cycle-by-cycle protection method includes steps of: (a) determining main switches and synchronous rectification switches; (b) controlling the main switches to operate in a normal mode; (c) detecting a current flowing through the inductor, and determining whether the current exceeds a threshold; (d) when the current exceeds the threshold, defining the main switch in an on state and having shortest turn-on duration as a target main switch, switching the target main switch to a current limiting mode for turning it off; and (e) after switching the target main switch to the current limiting mode, if the current is lower than the threshold, at a moment when a falling edge of control signals in a reference mode for the main switches first appears, switching the target main switch to a state in the reference mode corresponding to the moment.

Abstract: The disclosure provides a display panel, a manufacturing method thereof and a display device, relating to a field of display technology. The display panel includes a base substrate, a driving layer and a light-emitting layer. The light-emitting units formed by the light-emitting layer includes a first electrode layer, a first insulating layer, a control electrode layer, a second insulating layer, an active layer, a second electrode layer, and an organic light-emitting layer sequentially distributed. In the embodiments of the present disclosure, the second insulating layer is configured to separate the control electrode layer from the organic light-emitting layer and the active layer.

Abstract: A computerized method determines erasure coding (EC) formats for data extents in storage systems. Traffic history data of a data extent to be stored in the storage system is obtained. Estimated future traffic data is generated using a traffic estimation model, wherein the traffic history data is provided to the model as input. A current storage system constraint is calculated using the obtained traffic history data, and a constraint adjustment value is determined using a proportional, integral, derivative (PID) controller based on the current storage system constraint. An EC format for the data extent is determined using the estimated future traffic data and the determined constraint adjustment value and the data extent is stored in the storage system using the determined EC format. Use of the model and the PID controller balances optimized storage use with efficient data traffic handling.

Abstract: A computer-implemented method of fusing multiple images, where the multiple images are taken at different focal planes on a same field of view (FOV). The method includes the steps of a) to each one of the multiple images, performing Laplacian pyramid decomposition to generate a first pyramid; b) fusing the first pyramids of the multiple images to obtain a fused pyramid under guidance of energy maps respectively corresponding to each one of the multiple mages; c) performing a dynamic weighting of the fused pyramid to generate a weighted pyramid; and d) reconstructing a fusion image of the FOV from the weighted pyramid. The invention provides further a computer-implemented method of generating a depth map based on multiple images.

Abstract: A glass assembly includes a first glass layer including a first surface facing an exterior of a vehicle and a second surface opposite to the first surface; a second glass layer including a third surface and a fourth surface opposite to the third surface, the fourth surface facing an interior of the vehicle, and a light-adjusting layer between the first glass layer and the second glass layer, wherein the glass assembly further includes a light-emitting structure on the third surface or the fourth surface of the second glass layer, and wherein the second glass layer is used for reflecting incident light emitted by a light source and emitting the light into the interior of the vehicle through the light-emitting structure.

Abstract: A display panel includes a transparent substrate layer, a thin film transistor layer on a side of the transparent substrate layer, a first pixel defining layer on a side of the thin film transistor layer away from the transparent substrate layer and having a plurality of first openings, a plurality of bottom emitting type light emitting devices arranged in an array in the plurality of first openings and on the side of the thin film transistor layer away from the transparent substrate layer, a second pixel defining layer on a side of the transparent substrate layer away from the thin film transistor layer and having a plurality of second openings, and a wavelength converting layer having a plurality of wavelength converting units, each of the wavelength converting units being disposed in one of the second openings and in contact with the transparent substrate layer.

Abstract: According to an aspect, there is provided an apparatus (10) for moderating a skin lesion detection model (30). The apparatus (10) comprising a processor (12) and a memory (11). The processor (12) is configured to: receive user data (13) associated with a user; receive an output of the skin lesion detection model (14); modify the output of the skin lesion detection model (14) in accordance with the user data (13) to provide a modified output (15) indicative of skin lesion detection for the user; and output the modified output (15).

Abstract: A knowledge graph-driven groundwater-oriented method for building risk warning includes: extracting a relationship quadruple between groundwater level change and building structure change based on collected groundwater level data and building data; creating a cross-domain knowledge graph based on the relationship quadruple, and associating two different fields; updating the cross-domain knowledge graph in real time to realize the building risk warning caused by groundwater level changes. The risk warning is based on the causal relationship reflected in the factual data, making the risk warning more accurate, which can effectively solve the problem of the lack of risk warning system for buildings due to groundwater level changes in the related art.

Abstract: A device and a method for evaluating cervical spine proprioception are provided. The method includes: taking a first head movement under a movement posture as a reference, calculating angle differences between multiple head movements under the same movement posture and the first head movement, and averaging the angle differences to obtain an average angle difference; then operating a data terminal to calculate average angle differences under multiple movement postures, and averaging the average angle differences to obtain a resultant average angle difference; comparing the resultant average angle difference with a standard value, thereby evaluating cervical spine proprioception of the subject based on a difference between the resultant average angle difference and the standard value. The disclosure can accurately evaluate position errors of a cervical spine under different postures, thereby avoiding errors caused by manual measurement.

Abstract: A computer-implemented system assists resolution of service cases for medical imaging devices by retrieving device and case data, estimating likelihoods and timeframes for multiple resolution pathways, and presenting results in a user interface. Input may include images of device error messages captured by a camera; optical character recognition extracts text, and language detection and translation normalize messages for analysis. Models leverage historical repair data, technician profiles, and part replacement indicators to score pathways and forecast durations. A cost metric can combine likelihood and timeframe with service and scheduling costs to recommend actions and trigger service calls. The approach reduces downtime and improves dispatch and repair efficiency across customer and provider personnel.

Abstract: Provided are a point cloud encoding method and decoding method, and an encoder and a decoder. The encoding method includes: processing attribute information of a target point in a point cloud, so as to obtain a predicted residual of the attribute information of the target point; quantizing the predicted residual on the basis of a quantized weight of the target point and a quantized stride of the target point, so as to obtain a quantized residual of the attribute information of the target point, wherein the quantized weight of the target point is the weight used when weighting the quantized stride of the target point; and encoding the quantized residual, so as to obtain a code stream.

Abstract: The present disclosure is directed to methods for making compounds of structural formula (I): (I), wherein PG is defined above herein, which are useful for making antibody-drug conjugates. The present disclosure is also directed to processes for making related payload compounds, related Linker-Payload compounds, and to compounds that are useful as synthetic intermediates for making the compounds of formula (I).

Abstract: Nutraceutical compositions and methods of their use in treating Caliciviridae family viruses are provided. The viruses can be norovirus or sapovirus. An exemplary nutraceutical composition includes Fagopyrum dibotrys extract. Another nutraceutical composition for treating viral gastroenteritis includes 5, 7, 3?, 4?-tetrahydroxyflavan-3-ol C4-C8 dimers, quercetin, rutin, or a combination thereof. The nutraceutical compositions inhibit or reduce entry of Caliciviridae family viruses into intestinal epithelial cells of the subject.

Abstract: A vehicle window glass adapted to be cooperated with a projection device to provide a projection function, wherein the vehicle window glass includes a first glass body, a second glass body, a haze adjusting layer sandwiched between the first glass body and the second glass body, and an imaging layer, and wherein the haze adjusting layer is configured to be capable of adjusting its haze to provide a projection effect and/or a privacy effect toward the outside and/or the inside of the vehicle on the imaging layer.

Abstract: The present application relates to a control method of an aerial vehicle. The aerial vehicle may comprise a propulsion structure for providing flight power and a spraying apparatus for spraying a material. The control method may comprise determining current target information of the aerial vehicle during a process of the aerial vehicle performing a spraying task, wherein the current target information indicates wind field strength of a downward pressure wind field generated by the propulsion structure; determining, based on the current target information, a desired relative flight altitude of the aerial vehicle corresponding to the current target information relative to the material being sprayed below the aerial vehicle; and controlling the aerial vehicle to fly toward the desired relative flight altitude.

Abstract: An organic light-emitting display panel and a preparation method therefor, and a display apparatus. The organic light-emitting display panel comprises: a substrate; a plurality of organic light-emitting diodes, wherein the plurality of organic light-emitting diodes are located on the substrate, and each of the organic light-emitting diodes is provided with a first electrode, a second electrode, and a light-emitting layer and a hole injection layer which are located between the first electrode and the second electrode; and anti-crosstalk isolation electrodes, wherein each of the anti-crosstalk isolation electrodes is located at a gap between two adjacent organic light-emitting diodes, the anti-crosstalk isolation electrodes are configured to connect to a fixed voltage, and a voltage difference between each anti-crosstalk isolation electrode and each second electrode is less than a voltage difference between each first electrode and each second electrode.