Patents by Inventor Lucien Nedelec

Lucien Nedelec has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4154852
    Abstract: Novel 7-aminobenzocycloheptenes of the formula ##STR1## wherein X is selected from the group consisting of --NO.sub.2, --NH.sub.2, CH.sub.3 O-- and --OH, R.sub.1 is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms, R.sub.2 is alkyl of 1 to 5 carbon atoms and R.sub.1 and R.sub.2 together with the nitrogen atom to which they are attached form a saturated heterocycle of 4 to 6 ring carbon atoms optionally containing a second heteroatom in the ring and optionally substituted with an alkyl of 1 to 5 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts in optically active or racemic mixture form having antidepressant activity and a process for their preparation.
    Type: Grant
    Filed: September 20, 1977
    Date of Patent: May 15, 1979
    Assignee: Roussel Uclaf
    Inventors: Lucien Nedelec, Daniel Frechet, Claude Dumont
  • Patent number: 4148919
    Abstract: 7-AMINO-6,7-DIHYDRO [5H] benzocycloheptenes of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, chlorine, bromine and iodine in 2- or 4- position of the ring when halogen and R is selected from the group consisting of hydrogen and phenyl alkyl of 7 to 10 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having antidepressive activity and a process for their preparation and novel intermediates.
    Type: Grant
    Filed: July 26, 1976
    Date of Patent: April 10, 1979
    Assignee: Roussel Uclaf
    Inventors: Lucien Nedelec, Andre Pierdet, Claude Dumont, Marie-Helene Kannengiesser
  • Patent number: 4136179
    Abstract: 2,2-DIMETHYL-19-NOR-STEROIDS OF THE FORMULA ##STR1## wherein R.sub.1 is selected from the group consisting of hydrogen, ##STR2## and R.sub.2 is selected from the group consisting of hydrogen and hydrocarbon of 1 to 17 carbon atoms and the dotted lines indicate the optional presence of a double bond in 9(10) and 11(12) positions having antialdosteronic activity and an increased sodium diuresis with conservation of organic potassium and their preparation and novel intermediates.
    Type: Grant
    Filed: September 7, 1977
    Date of Patent: January 23, 1979
    Assignee: Roussel Uclaf
    Inventors: Lucien Nedelec, Vesperto Torelli, Robert Fournex
  • Patent number: 4130658
    Abstract: Novel phenethylamines of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, acyl of an aliphatic carboxylic acid of 2 to 6 carbon atoms and benzoyl and Y is selected from the group consisting of hydrogen and --OX and their non-toxic, pharmaceutically acceptable acid addition salts having dopaminergic stimulating activity and their preparation and novel intermediates.
    Type: Grant
    Filed: June 24, 1977
    Date of Patent: December 19, 1978
    Assignee: Roussel Uclaf
    Inventors: Lucien Nedelec, Daniel Frechet, Claude Dumont
  • Patent number: 4117164
    Abstract: Novel 7-aminomethyl-benzocycloheptenes of the formula ##STR1## wherein X is selected from the group consisting of nitro, amino, methoxy and hydroxy, R.sub.1 is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms and R.sub.2 is alkyl of 1 to 5 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having antidepressant activity and their preparation.
    Type: Grant
    Filed: November 10, 1977
    Date of Patent: September 26, 1978
    Assignee: Roussel Uclaf
    Inventors: Lucien Nedelec, Daniel Frechet, Claude Dumont
  • Patent number: 4100278
    Abstract: Novel benzazepines of the formula ##STR1## wherein n is 0 or 1 and R and R.sub.1 are individually selected from the group consisting of hydrogen and methyl with the proviso that when R.sub.1 is methyl, R is also methyl and their non-toxic, pharmaceutically acceptable acid addition salts having antidepressive activity and novel intermediates and processes for the preparation of the said compounds.
    Type: Grant
    Filed: March 30, 1977
    Date of Patent: July 11, 1978
    Assignee: Roussel Uclaf
    Inventors: Lucien Nedelec, Daniel Frechet, Claude Dumont, Marie-Helene Kannengiesser
  • Patent number: 4091115
    Abstract: Novel 7-amino-benzocycloheptenes of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, chlorine, bromine and iodine in the 2- or 4-position when a halogen, Y and Z are hydrogen or together form a double bond, R is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms and phenyl optionally substituted with fluorine, chlorine, methyl or methoxy, R.sub.1 is selected from the group consisting of hydrogen, alkyl of 1 to 5 carbon atoms and alkenyl of 2 to 5 carbon atoms and R.sub.2 is selected from the group consisting of alkyl of 1 to 5 carbon atoms and alkenyl of 2 to 5 carbon atoms and R.sub.1 and R.sub.
    Type: Grant
    Filed: July 26, 1976
    Date of Patent: May 23, 1978
    Assignee: Roussel Uclaf
    Inventors: Lucien Nedelec, Andre Pierdet, Claude Dumont, Marie-Helene Kannengiesser
  • Patent number: 4078059
    Abstract: Novel 2,2-dimethyl steroids of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, --OH and ##STR2## R.sub.1 is selected from the group consisting of hydrogen and hydrocarbon of 1 to 17 carbon atoms Z is selected from the group consisting of hydrogen and ##STR3## in the .alpha.-position, R.sub.2 is alkyl of 1 to 4 carbon atoms and the dotted line in the B ring indicates the optional presence of a double bond in the 6(7) position having antialdosterone activity and increasing sodium diuresis while conserving organic potassium.
    Type: Grant
    Filed: August 31, 1976
    Date of Patent: March 7, 1978
    Assignee: Roussel UCLAF
    Inventors: Lucien Nedelec, Vesperto Torelli, Robert Fournex
  • Patent number: 4072685
    Abstract: Novel phenyl piperidines of the formula ##STR1## wherein X is selected from the group consisting of hydrogen and acyl of an aliphatic carboxylic acid of 2 to 6 carbon atoms and R is selected from the group consisting of alkyl of 1 to 5 carbon atoms, alkenyl of 2 to 5 carbon atoms and phenyl alkyl of 1 to 3 alkyl carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having dopaminergic properties and certain of the compounds possess hypotensive properties.
    Type: Grant
    Filed: May 13, 1976
    Date of Patent: February 7, 1978
    Assignee: Roussel Uclaf
    Inventors: Lucien Nedelec, Jacques Guillaume, Claude Dumont
  • Patent number: 4046901
    Abstract: Novel compounds selected from the group consisting of phenylpiperidines of the formula ##STR1## wherein X is selected from the group consisting of hydrogen and an acyl of aliphatic carboxylic acid of 2 to 6 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts possessing dopaminergic properties and some of which possess hypotensive properties and their preparation.
    Type: Grant
    Filed: May 13, 1976
    Date of Patent: September 6, 1977
    Assignee: Roussel-UCLAF
    Inventors: Lucien Nedelec, Jacques Guillaume, Claude Dumont
  • Patent number: 4009273
    Abstract: Racemates and optically active isomers of a compound selected from the group consisting of a compound of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, lower alkyl optionally substituted with a member of the group consisting of hydroxy and halogen, lower alkenyl, lower alkynyl, --(CH.sub.2).sub.n -- COCH.sub.3 where n is 0 or 1, ##STR2## wherein X is selected from the group consisting of lower alkyl and optionally substituted phenyl, aralkyl or 7 to 8 carbon atoms, acyl of an organic carboxylic acid of 1 to 6 carbon atoms optionally substituted with ##STR3## where m is an integer from 0 to 6 and X.sub.1 is selected from the group consisting of hydrogen and lower alkyl, ##STR4## where p is an integer from 1 to 6 and X.sub.1 is as before and ##STR5## wherein X.sub.2 is lower alkyl and R.sub.1 and R.sub.
    Type: Grant
    Filed: April 14, 1975
    Date of Patent: February 22, 1977
    Assignee: Roussel-UCLAF
    Inventors: Lucien Nedelec, Daniel Frechet
  • Patent number: 3931151
    Abstract: Novel dibenzo (b,f) azepines of the formula ##SPC1##Wherein R is alkyl of 1 to 4 carbon atoms, R.sub.1 is selected from the group consisting of hydrogen and alkyl of 1 to 4 carbon atoms, n is 0, 1 or 2 and AlK is alkyl of 1 to 2 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having antidepressant and neurosedative activity.
    Type: Grant
    Filed: October 3, 1973
    Date of Patent: January 6, 1976
    Assignee: Roussel-UCLAF
    Inventors: Lucien Nedelec, Jacques Guillaume, Andre Allais