Patents by Inventor Ludmila Pavlova

Ludmila Pavlova has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8349550
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Grant
    Filed: December 2, 2010
    Date of Patent: January 8, 2013
    Assignees: Cytosorbents, Inc.
    Inventors: James A Brady, James F Winchester, Vadim Davankov, Maria Tsvurupa, Ludmila Pavlova, Frank M Norris, Peter J Quartararo, Jr., Jamie A Salsberg
  • Patent number: 8334094
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Grant
    Filed: May 20, 2010
    Date of Patent: December 18, 2012
    Assignees: Cytosorbents, Inc.
    Inventors: James A Brady, James F Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M Norris, Peter Quartararo, Jr., Jamie A Salsberg
  • Patent number: 8329388
    Abstract: Devices, systems, and methods reduce levels of proinflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among proinflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of proinflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among proinflammatory or anti-inflammatory stimulators or mediators.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: December 11, 2012
    Assignees: Cytosorbents, Inc.
    Inventors: James A Brady, James F Winchester, Vadim Davankov, Maria Tsvurupa, Ludmila Pavlova, Frank M Norris, Peter J Quartararo, Jr., Jamie A Salsberg
  • Publication number: 20110097700
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: December 2, 2010
    Publication date: April 28, 2011
    Inventors: James A. Brady, James F. Winchester, Vadim Davankov, Maria Tsvurupa, Ludmila Pavlova, Frank M. Norris, Peter J. Quartararo, JR., Jamie A. Salsberg
  • Publication number: 20110004152
    Abstract: Devices, systems, and methods reduce levels of proinflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among proinflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of proinflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among proinflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: September 9, 2010
    Publication date: January 6, 2011
    Inventors: James A. Brady, James F. Winchester, Vadim Davankov, Maria Tsvurupa, Ludmila Pavlova, Frank M. Norris, Peter J. Quartararo, JR., Jamie A. Salsberg
  • Patent number: 7846650
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Grant
    Filed: December 18, 2007
    Date of Patent: December 7, 2010
    Assignees: Cytosorbents, Inc.
    Inventors: James A Brady, James F Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M Norris, Peter J Quartararo, Jr., Jamie A Salsberg
  • Publication number: 20100233673
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems; and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: May 20, 2010
    Publication date: September 16, 2010
    Inventors: James A Brady, James F Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M Norris, Peter Quartararo, JR., Jamie A Salsberg
  • Publication number: 20100069816
    Abstract: Devices, systems, and methods reduce levels of proinflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among proinflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of proinflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among proinflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: July 6, 2009
    Publication date: March 18, 2010
    Inventors: James A. Brady, James F. Winchester, Vadim Davankov, Maria Tsyunupa, Ludmila Pavlova, Frank M. Norris, Peter J. Quartararo, JR., Jamie A. Salsberg
  • Patent number: 7556768
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Grant
    Filed: April 4, 2007
    Date of Patent: July 7, 2009
    Assignees: MedaSorb Corporation
    Inventors: James A Brady, James F Winchester, Vadim Davankov, Maria Tsyuruoa, Ludmila Pavlova, Frank M Norris, Peter J Quartararo, Jr., Jamie A Salsberg
  • Publication number: 20080138434
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: December 18, 2007
    Publication date: June 12, 2008
    Inventors: James A. Brady, James F. Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M. Norris, Peter J. Quartararo, Jamie A. Salsberg
  • Patent number: 7312023
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Grant
    Filed: November 3, 2004
    Date of Patent: December 25, 2007
    Assignee: RenalTech International, LLC
    Inventors: James A Brady, James F Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M Norris, Peter J Quartararo, Jr., Jamie A Salsberg
  • Publication number: 20070292429
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: April 4, 2007
    Publication date: December 20, 2007
    Inventors: James Brady, James Winchester, Vadim Davankov, Maria Tsyuruoa, Ludmila Pavlova, Frank Norris, Peter Quartararo, Jamie Salsberg
  • Publication number: 20070258983
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: November 3, 2004
    Publication date: November 8, 2007
    Inventors: James Brady, James Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank Norris, Peter Quartararo, Jamie Salsberg
  • Publication number: 20070093739
    Abstract: Intravenous, or indwelling, or integratedmulti-functional devices and systems reduce levels of a targeted compound in blood by selective adsorption. The devices and systems can be used, e.g., to reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices and systems are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices and systems serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: December 5, 2006
    Publication date: April 26, 2007
    Inventors: James Brady, James Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank Norris, Peter Quartararo, Jamie Salsberg
  • Publication number: 20060057142
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: October 19, 2005
    Publication date: March 16, 2006
    Inventors: James Brady, James Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank Norris, Peter Quartararo, Jamie Salsberg
  • Publication number: 20050239041
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: April 13, 2005
    Publication date: October 27, 2005
    Inventors: James Brady, James Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank Norris, Peter Quartararo, Jamie Salsberg
  • Patent number: 6878127
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in blood by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Grant
    Filed: December 21, 2001
    Date of Patent: April 12, 2005
    Assignee: RenalTech International, LLC
    Inventors: James A Brady, James F Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank M Norris, Peter J Quartararo, Jr., Jamie A Salsberg
  • Publication number: 20050061742
    Abstract: Devices, systems, and methods reduce levels of pro-inflammatory or anti-inflammatory stimulators or mediators in physiologic fluid by selective adsorption. The devices, systems, and methods are useful in situations where abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators occur, or during events that do induce or have the potential for inducing abnormal production of pro-inflammatory or anti-inflammatory stimulators or mediators. The devices, systems, and methods serve to prevent, control, reduce, or alleviate the severity of the inflammatory response and disease states that are associated with abnormal levels of or unregulated or excessive interaction among pro-inflammatory or anti-inflammatory stimulators or mediators.
    Type: Application
    Filed: November 4, 2004
    Publication date: March 24, 2005
    Inventors: James Brady, James Winchester, Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Frank Norris, Peter Quartararo, Jamie Salsberg
  • Publication number: 20040001800
    Abstract: A hemo- and biocompatible polymeric adsorbing material for purification of physiological fluids of organism has a plurality of beads each having a generally hydrophobic core provided with a plurality of pores, and a hydrophilic hemo- and biocompatible coating which coats at least a part of a surface of the core, wherein a thickness of the hemo- and biocompatible coating is selected between about 20 angstrom and about 1 micron. A method of producing the material includes the new coating of the surface of the core. A device for and a method of purification of physiological fluids of organism includes the use of the new material.
    Type: Application
    Filed: September 24, 2001
    Publication date: January 1, 2004
    Inventors: Vadlm Davankov, Ludmila Pavlova, Peter Quartararo, Maria Tsyurupa
  • Publication number: 20030125656
    Abstract: A hemo-and bio compatible beaded polymeric adsorbing material for purification of physiological fluids of organism has a plurality of beads each having a core with a hydrophobic core surface, and a hydrophilic, hemo-and biocompatible coating applied on the core surface of the core, so that the hemo-and biocompatible coating is applied non-continuously so as to leave on the core surface of the core such areas which are not covered with the hemo-and biocompatible coating and therefore remain hydrophobic, with the areas having a size which is substantially smaller than a size of an individual cell of the physiological fluid, so that when the physiological fluid passes through the material the individual cell of the physiological fluid can substantially be in contact only with the hemo-and biocompatible coating and can not contact the hydrophobic core surface of the core because the corresponding areas of the core surface which are exposed between parts of the hemo-and biocompatible hydrophilic coating have a sma
    Type: Application
    Filed: December 31, 2001
    Publication date: July 3, 2003
    Inventors: Vadim Davankov, Maria Tsyurupa, Ludmila Pavlova, Ilya Zborovsky