Patents by Inventor Luis G. Cascao-Pereira

Luis G. Cascao-Pereira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TS-23 alpha-amylase variants with altered properties
    Patent number: 8962283
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: February 24, 2015
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, Claudine Chang, Clement Choy, James T. Kellis, Jr., Brian E. Jones, Melodie Estabrook, Marc Kolkman, Chris Leeflang, Casper Vroemen, Walter Weyler
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20150031589
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: July 21, 2014
    Publication date: January 29, 2015
    Applicant: DANISCO US INC.
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulose, Brian F. Schmidt
  • PROTEASES COMPRISING ONE OR MORE COMBINABLE MUTATIONS
    Publication number: 20140308736
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Application
    Filed: May 2, 2014
    Publication date: October 16, 2014
    Applicant: DANISCO US INC.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.
  • Variant Maltohexaose-Forming Alpha-Amylase Variants
    Publication number: 20140287477
    Abstract: Disclosed are compositions and methods relating to variant maltohexaose-forming alpha-amylases. The variant alpha-amylases are useful, for example, for starch liquefaction and saccharification, for cleaning starchy stains in laundry, dishwashing, and other applications, for textile processing (e.g., desizing), in animal feed for improving digestibility, and for baking and brewing.
    Type: Application
    Filed: October 26, 2012
    Publication date: September 25, 2014
    Applicant: DANISCO US INC.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, Marc Kolkman, Harm Mulder
  • Protease comprising one or more combinable mutations
    Patent number: 8753861
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: June 17, 2014
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, Jr.
  • Compositions and Methods Comprising Serine Protease Variants
    Publication number: 20140154782
    Abstract: The present invention provides serine protease variants, more specifically subtilisin variants produced there from. Specifically, the present invention provides serine protease variants, more specifically subtilisin variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants, more specifically subtilisin variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants, more specifically subtilisin variants.
    Type: Application
    Filed: May 4, 2012
    Publication date: June 5, 2014
    Applicant: DANISCO US INC.
    Inventors: Neelam S. Amin, Katherine Augustyn, Joshua R. Basler, Luis G. Cascao-Pereira, Katherine D. Collier, Edward M. Concar, David A. Estell, James T. Kellis, JR., Euan John Magennis, Alexander Pisarchik, Ayrookaran J. Poulose, Philip Frank Souter, Glenn Steven Ward, Jian Yao
  • Compositions and methods comprising protease variants
    Patent number: 8728790
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Grant
    Filed: December 9, 2010
    Date of Patent: May 20, 2014
    Assignee: Danisco US Inc.
    Inventors: Joshua R Basler, Luis G Cascão-Pereira, David A Estell, James T Kellis, Jr., Alexander Pisarchik, Ayrookaran J. Poulose, Daniel E. Torres Pazmino
  • TS-23 Alpha-Amylase Variants With Altered Properties
    Publication number: 20130344542
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Application
    Filed: May 21, 2013
    Publication date: December 26, 2013
    Inventors: Luis G. Cascao-Pereira, Claudine Chang, Clement Choy, James T. Kellis, JR., Brian E. Jones, Melodie Estabrook, Marc Kolkman, Chris Leeflang, Casper Vroemen, Walter Weyler
  • TS-23 alpha-amylase variants with altered properties
    Patent number: 8460916
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Grant
    Filed: July 2, 2012
    Date of Patent: June 11, 2013
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, Claudine Chang, Clement Choy, James T. Kellis, Jr., Brian E. Jones, Melodie Estabrook, Marc Koklman, Chris Leeflang, Casper Vroeman, Walter Weyler
  • ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES
    Publication number: 20130011882
    Abstract: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and which exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions comprise an additional enzyme such as a phytase. Also disclosed are methods of using the compositions, and kits related thereto.
    Type: Application
    Filed: May 15, 2012
    Publication date: January 10, 2013
    Applicant: DANISCO US INC.
    Inventors: LUIS G. CASCÃO-PEREIRA, JAMES T. KELLIS, JR., BRADLEY A. PAULSON, SCOTT D. POWER, SANDRA W. RAMER, VIVEK SHARMA, ANDREW SHAW, JAYARAMA K. SHETTY, DONALD E. WARD
  • TS-23 ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES
    Publication number: 20130005029
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Application
    Filed: July 2, 2012
    Publication date: January 3, 2013
    Applicant: Danisco US Inc., Genencor Division
    Inventors: Luis G. CASCAO-PEREIRA, Claudine Chang, Clement Choy, James T. Kellis, JR., Brain E. Jones, Melodie Estabrook, Marc Kolkman, Chris Leeflang, Casper Vroemen, Walter Weyler
  • Variant alpha-amylases from and methods of uses, thereof
    Patent number: 8323945
    Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.
    Type: Grant
    Filed: June 5, 2009
    Date of Patent: December 4, 2012
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, William A. Cuevas, David A. Estell, Sang-Kyu Lee, Scott D. Power, Sandra W. Ramer, Amr Toppozada, Louise Wallace
  • COMPOSITIONS AND METHODS COMPRISING CELLULASE VARIANTS WITH REDUCED AFFINITY TO NON-CELLULOSIC MATERIALS
    Publication number: 20120276595
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.
    Type: Application
    Filed: July 6, 2012
    Publication date: November 1, 2012
    Applicant: DANISCO US INC.
    Inventors: Luis G. Cascao-Pereira, Thijs Kaper, Bradley R. Kelemen, Amy D. Liu
  • TS23 alpha-amylase variants with altered properties
    Patent number: 8236545
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Grant
    Filed: February 4, 2009
    Date of Patent: August 7, 2012
    Assignee: Danisco US Inc., Genencor Division
    Inventors: Luis G. Cascao-Pereira, Claudine Chang, Clement Choy, James T. Kellis, Jr., Brian E Jones, Melodie Estabrook, Marc Kolkman, Chris Leeflang, Casper Vroemen, Walter Weyler
  • Compositions and methods comprising cellulase variants with reduced affinity to non-cellulosic materials
    Patent number: 8236542
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.
    Type: Grant
    Filed: June 3, 2009
    Date of Patent: August 7, 2012
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, Thijs Kaper, Bradley R Kelemen, Amy D. Liu
  • Compositions and methods comprising a subtilisin variant
    Patent number: 8183024
    Abstract: The present invention provides a subtilisin variant that is particularly well suited to cleaning applications. In particular, the present invention provides a Bacillus sp. subtilisin variant and cleaning compositions comprising this variant.
    Type: Grant
    Filed: November 10, 2009
    Date of Patent: May 22, 2012
    Assignee: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, Jr., Ayrookaran J. Poulise
  • Protease Comprising One Or More Combinable Mutations
    Publication number: 20120003718
    Abstract: The present invention provides engineered protease variants. In particular, the protease variants comprise combinable mutations at selected surface positions that affect the charge and/or hydrophobicity of the enzyme to enhance at least one desired property of the resulting variant enzyme in a chosen application. Compositions comprising the protease variants, and methods for using the same are also provided.
    Type: Application
    Filed: November 10, 2009
    Publication date: January 5, 2012
    Applicant: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.
  • Compositions and Methods Comprising Protease Variants
    Publication number: 20110262999
    Abstract: The present invention provides protease variants, compositions comprising protease variants, and methods of using such protease variants and compositions.
    Type: Application
    Filed: December 9, 2010
    Publication date: October 27, 2011
    Applicant: Danisco US Inc.
    Inventors: Joshua R. Basler, Luis G. Cascão-Pereira, David A. Estell, James T. Kellis, JR., Alexander Pisarchik, Ayrookaran J. Poulose, Daniel Torres Pazmino
  • Compositions And Methods Comprising Variant Microbial Proteases
    Publication number: 20110256610
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant proteases suitable for laundry cleaning applications.
    Type: Application
    Filed: June 3, 2009
    Publication date: October 20, 2011
    Inventors: Viktor Yuryevich Alekseyev, Luis G. Cascao-Pereira, James T. Kellis, JR., Alexander Pisarchik
  • Compositions And Methods Comprising Variant Microbial Proteases
    Publication number: 20110256609
    Abstract: The present invention provides variant subtilisins and compositions comprising at least one variant subtilisin set forth herein, as well as methods for using these variants and compositions. In some embodiments, the present invention provides variant subtilisins suitable for laundry cleaning applications.
    Type: Application
    Filed: June 3, 2009
    Publication date: October 20, 2011
    Inventors: Joshua R. Basler, Luis G. Cascao-Pereira, David A. Estell, James T. Kellis, JR.