Patents by Inventor Luis G. Cascao-Pereira

Luis G. Cascao-Pereira has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions And Methods Comprising Variant Microbial Proteases
    Publication number: 20110251073
    Abstract: The present invention provides methods for protein engineering. Specifically, the invention provides methods utilizing site evaluation libraries to design libraries that optimize two or more properties of a protein. The present invention also provides variant subtilisins suitable for various uses.
    Type: Application
    Filed: June 3, 2009
    Publication date: October 13, 2011
    Inventors: Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR.
  • COMPOSITIONS AND METHODS COMPRISING SERINE PROTEASE VARIANTS
    Publication number: 20100192985
    Abstract: The present invention provides methods for protein engineering and serine protease variants produced there from. Specifically, the present invention provides serine protease variants having one or more substitutions as compared to a reference serine protease. In addition, the present invention provides compositions comprising these serine protease variants. In some embodiments, the present invention provides cleaning compositions comprising at least one of these serine protease variants.
    Type: Application
    Filed: November 10, 2009
    Publication date: August 5, 2010
    Inventors: Wolfgang Aehle, Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulose, Brian F. Schmidt
  • COMPOSITIONS AND METHODS COMPRISING A SUBTILISIN VARIANT
    Publication number: 20100152087
    Abstract: The present invention provides a subtilisin variant that is particularly well suited to cleaning applications. In particular, the present invention provides a Bacillus sp. subtilisin variant and cleaning compositions comprising this variant.
    Type: Application
    Filed: November 10, 2009
    Publication date: June 17, 2010
    Inventors: Luis G. Cascao-Pereira, David A. Estell, Frits Goedegebuur, James T. Kellis, JR., Ayrookaran J. Poulise
  • TS23 Alpha-Amylase Variants With Altered Properties
    Publication number: 20100048446
    Abstract: Described are variants (mutants) of a parent alpha-amylase having alpha-amylase activity and exhibiting altered properties relative to the parent alpha-amylase, and methods of use, thereof.
    Type: Application
    Filed: February 4, 2009
    Publication date: February 25, 2010
    Applicant: DANISCO US INC., GENENCOR DIVISION
    Inventors: Luis G. Cascao-Pereira, Claudine Chang, Clement Choy, James T. Kellis, JR., Brian E. Jones, Melodie Estabrook, Marc Kolkman, Chris Leeflang, Casper Vroemen, Walter Weyler
  • Compositions and Methods Comprising Cellulase Variants with Reduced Affinity to Non-Cellulosic Materials
    Publication number: 20100041104
    Abstract: The present disclosure relates to cellulase variants. In particular the present disclosure relates to cellulase variants having reduced binding to non-cellulosic materials. Also described are nucleic acids encoding the cellulase, compositions comprising said cellulase, methods of identifying cellulose variants and methods of using the compositions.
    Type: Application
    Filed: June 3, 2009
    Publication date: February 18, 2010
    Applicant: Danisco US Inc.
    Inventors: Luis G. Cascao-Pereira, Thijs Kaper, Bradley R. Kelemen, Amy D. Liu
  • Variant Alpha-Amylases from Bacillus Subtilis and Methods of Uses, Thereof
    Publication number: 20100015686
    Abstract: Alpha-amylases from Bacillus subtilis (AmyE), variants thereof, nucleic acids encoding the same, and host cells comprising the nucleic acids are provided. Methods of using AmyE or variants thereof are disclosed, including liquefaction and/or saccharification of starch. Such methods may yield sugars useful for ethanol production or high fructose corn syrup production. In some cases, the amylases can be used at low pH, in the absence of calcium, and/or in the absence of a glucoamylase.
    Type: Application
    Filed: June 5, 2009
    Publication date: January 21, 2010
    Applicant: Danisco US Inc., Genencor Division
    Inventors: Luis G. Cascao-Pereira, William A. Cuevas, David A. Estell, Sang-Kyu Lee, Scott D. Power, Sandra W. Ramer, Amr Toppozada, Louise Wallace
  • PRODUCTION OF GLUCOSE FROM STARCH USING ALPHA-AMYLASES FROM BACILLUS SUBTILIS
    Publication number: 20090305935
    Abstract: An ?-amylase from Bacillus subtilis (AmyE) produces significant amounts of glucose from various carbohydrate substrates, including vegetable starch, maltoheptaose, and maltotriose. Among other things, this advantageous property allows AmyE or variants thereof to be used in a saccharification reaction having a reduced or eliminated requirement for glucoamylase. The reduction or elimination of the glucoamylase requirement significantly improves the efficiency of the production of ethanol or high fructose corn syrup, for example.
    Type: Application
    Filed: June 4, 2009
    Publication date: December 10, 2009
    Inventors: Luis G. CASCAO-PEREIRA, Regina CHIN, William A. CUEVAS, David A. ESTELL, Sang-Kyu LEE, Michael J. PEPSIN, Scott D. POWER, Sandra W. RAMER, Carol A. REQUADT, Andrew SHAW, Amr R. TOPPOZADA, Louise WALLACE
  • ALPHA-AMYLASE VARIANTS WITH ALTERED PROPERTIES
    Publication number: 20090252828
    Abstract: Disclosed are compositions comprising variants of alpha-amylase that have alpha-amylase activity and which exhibit altered properties relative to a parent AmyS-like alpha-amylase from which they are derived. The compositions comprise an additional enzyme such as a phytase. Also disclosed are methods of using the compositions, and kits related thereto.
    Type: Application
    Filed: November 3, 2008
    Publication date: October 8, 2009
    Applicant: Danisco US Inc., Genencor Division
    Inventors: Luis G. Cascao-Pereira, James T. Kellis, JR., Bradley A. Paulson, Scott D. Power, Sandra W. Ramer, Vivek Sharma, Andrew Shaw, Jayarama K. Shetty, Donald E. Ward